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133篇 您的检索式:作者名="PARRELLA P"
    题名 作者 年代 出处 被引量
1一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P 2014中华神经外科疾病研究杂志2014,13,5:6
2An update of the host range of Tomato spotted wilt virus显示文摘Parrella G Gognalons P Gebre- Selassie K 2003Journal of Plant Pathology2003,85,4:1
3Biological studies of Liriomyza huidobrensis (Diptera:Agromyzidae) on chrysanthemum,aster,and pea显示文摘PARRELLA M P BETHKE J A 1984J Econ Entomol1984,77,:1
4Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspiratesl显示文摘Parrella P Xiao Y Fliss M 2001Cancer Res2001,61,20:1
5Intraoperative infusion of amino acids induces anabolism independent of the type of anesthesia显示文摘Donatelli F Schricker T Parrella P 2006Anesth Analg2006,103,:1
6Predatory mites help control thrips on floriculture crops显示文摘Hessein N A Parrella M P 1990California Agriculture1990,44,6:1
7Biology of Liriomyza显示文摘Parrella M P 1997Ann Rev Entomo11997,,32:1
8Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors显示文摘Sanchez-Cespedes M Parrella P Nomoto S 2001Cancer Res2001,61,19:1
9Detection of mitochondrial DNA mutations in primary, breast cancer and fine-needle aspirates显示文摘Parrella P Yan X Fliss M 2001Cancer Res2001,61,20:1
10The Sublethal Effects of Selected Insecticides on Life Table Parameters of Panonychus cirri ( Acari: Tetranychidae) 显示文摘JONES V P PARRELLA M P 1984Can Entomol1984,116,7:1
11Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung显示文摘Sanchez-Cespedes M Parrella P Esteller M 2002Cancer Res2002,62,13:1
12Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung显示文摘Sanchez-Cespedes M Parrella P Esteller M 2002Cancer Res2002,62,13:1
13Detection of c-myc amplification in uveal melanoma by fluorescent in situ hybridization 显示文摘Parrella P Caballero OL Sidransky D 2001Invest Ophthalmol Vis Sci2001,42,8:1
14Mutations of the D310 mito- chondrial mononucleotide repeat in primary tumors and cytological specimens显示文摘Parrella P Seripa D Matera MG 2003Cancer Lett2003,190,1:1
15Sensitive detection of transitional cell carcinoma of the bladder by microsatellite analysis of cells exfoliated in urine显示文摘 Parrella P Gallucci M 2001Int J Cancer2001,5,6:1
16Field evaluations of augmentative releases of Delphastus catalinae(Horn) (Coleoptera: Coccinellidae) for suppression of Bemisia argentifolii Bellows & Perring (Homoptera: Aleyrodidae)infesting cotton显示文摘HEINZ K M BRAZZLE J R PARRELLA M P 1999Biological Control1999,16,:1
17Lack of BRAF mutation in primary uveal melanoma 显示文摘Cohen Y Goldenberg-Cohen N Parrella P 2003Invest Ophthalmol Vis Sci2003,44,7:1
18Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates显示文摘Parrella P Xiao Y Fliss M 2001Cancer Res2001,61,20:1
19Nonrandom distri-bution of aberrant promoter methylation of cancer-relat-ed genes in sporadic breast tumors 显示文摘Parrella P Poeta ML Gallo AP 2004Clin CancerRes2004,10,16:1
20Loss ofGATA-1 full length as a cause of Diamond-Blackfan anemiaphenotype 显示文摘PARRELLAS ASPESI A QUARELLO P 2014Pediatr Blood Cancer2014,61,7:1
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