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| 1 | Contrast-enhanced 3D ultrasound in the radiofrequency ablation of liver tumors显示文摘Liver metastases and hepatocellular carcinomas are two of the most common causes of cancer deaths in the world.Radiofrequency ablation(RFA) is a well recognized,effective and minimally invasive means of treating malignant hepatic tumors.This article describes the use of contrast-enhanced 3D ultrasound(CE-3DUS) in the staging,targeting and follow-up of patients with liver tumors undergoing RFA.In particular,its value in the management of large hepatic lesions will be illustrated.Current limitations of CE-3DUS and future developments in the technique will also be discussed.In summary,CE-3DUS is useful in the RFA of liver tumors with improved detection and display of occult lesions and recurrence,in the assessment of lesional geometry and orientation for a more accurate planning and guidance of multiple RFA needle electrodes in large tumors and in the evaluation of residual or recurrent disease within the immediate and/or subsequent follow-up periods. | Edward Leen Senthil Kumar Shahid A Khan Gavin Low Keh Oon Ong Paul Tait Mike Averkiou | 2009 | World Journal of Gastroenterology2009，15，3： | 19 |
| 2 | Intestinal stem cells and the colorectal cancer microenvironment显示文摘Colorectal cancer(CRC)remains a highly fatal condition in part due to its resilience to treatment and its propensity to spread beyond the site of primary occurrence.One possible avenue for cancer to escape eradication is via stem-like cancer cells that,through phenotypic heterogeneity,are more resilient than other tumor constituents and are key contributors to cancer growth and metastasis.These proliferative tumor cells are theorized to possess many properties akin to normal intestinal stem cells.Not only do these CRC'stem'cells demonstrate similar restorative ability,they also share many cell pathways and surface markers in common,as well as respond to the same key niche stimuli.With the improvement of techniques for epithelial stem cell identification,our understanding of CRC behavior is also evolving.Emerging evidence about cellular plasticity and epithelial mesenchymal transition are shedding light onto metastatic CRC processes and are also challenging fundamental concepts about unidirectional epithelial proliferation.This review aims to reappraise evidence supporting the existence and behavior of CRC stem cells,their relationship to normal stem cells,and their possible dependence on the stem cell niche. | Bryan A Ong Kenneth J Vega Courtney W Houchen | 2014 | World Journal of Gastroenterology2014，20，8： | 2 |
| 3 | Dictation as a technique for teaching composition显示文摘 | Ong K A | | 0，，： | 2 |
| 4 | Interoperability of Design Intent in Integrated Product and Process Design显示文摘Concurrent engineering is currently an overwhelming t rend in product development since it takes the down-stream product development issues and product life-cycle issues into consideration in up-front design pro cess. At this stage, evaluation, verification and validation of design concepts and design schemes is critical to the right-to-market product development. I dentification and extraction of design intent from the part digital mock-ups in different data formats and created in different CAD systems for DFX considerati on, evaluation, verification, and validation is crucial too. Traditionally, fro m manufacturing point of view, feature identification and extraction is to get t he features and feature-related information for manufacturing planning and inte gration. Presently, from the viewpoint of product development and product servi ce life cycle, design intent identification and extraction is to get all the des ign-related information for DFX consideration in early design stage, such as de sign for assembly, design for service, design for tooling, design for functional ity and design for environment etc. Therefore, how to successfully extract desi gn intent such as design and machining features and design-related information from the prototyping digital mock-ups created by different CAD systems for DFX consideration in upstream design stage is a very useful topic in integrated prod uct and process design and development. Presently, there are heterogeneous CAD systems in the market and the interoperat ion among the different CAD systems is indispensable. The interoperability of d ifferent CAD systems is by way of data exchanged technology such as STEP and IGE S. The critical weakness of this interoperation technology is that much of the design intent is lost in the interoperation process. Once the product digital m ock-ups is exchanged via data exchange technology such as IGES or STEP, the des ign intent including the dimension-driven design features and other attributes embedded in the part model are lost in the data translation process. Models rea d out of CAD systems come into other systems as featureless chunks of geometry e ntities. Obviously, the interoperation technology does not satisfy the industry need. It has been reported that this poor interoperation technology, which pro vides poor CAD models in neutral-format geometry had cost the automobile indust ry alone $1 billon per year. Fortunately, some researchers have been aware of t he criticality of this since only the United States industry spends billons of d ollars as a result of poor interoperability between computer-aided engineering software tools. In the past, product development was often done within a single company by co-located design team. In more recent years, there has been a busi ness paradigm shift in product development as the product development is being d one more often by geographically and temporally distributed design teams. There is a high level of outsourcing, not only of manufacturing but also of actual pr oduct development effort. Besides, product development across companies, and ev en within a single company, is often done within a heterogeneous software tool e nvironment. How to improve the interoperability of design intent created in het erogeneous software tool environment geographically has become a critical issue in next-generation product development system. Design intent in this research is defined as the outcome of design process. Des ign process goes from the identification of needs to satisfaction of that needs. Design intent satisfies this kind of needs. In this research, design intent i s created in a CAD system and embedded in part CAD model. The detailed design i ntent here includes design and manufacturing features and the feature-relat ed information such as feature parameters, feature relationships and some relate d characteristics such as associativity. Interoperability refers to the ability to share and communicate in the heterogeneous environment or heterogeneous soft | M W Fu W F Lu A Y C Nee S K Ong | 2002 | 厦门大学学报(自然科学版)2002，41，S1： | 2 |
| 5 | Proteolytic pattern and organic acid profiles of probiotic Cheeddar cheese as influenced by probiotic strains of Lactobacillus acidophilus, LactobaciUus paracasei, Lactobacillus casei or Bifidobacterium sp 显示文摘 | ONG L HENRIKSSON A SHAH N P | 2007 | International Dairy Journal2007，17，1： | 1 |
| 6 | An evaluation ot the use ot two-dimensional gel electrophoresis in proteomics显示文摘 | Ong SE Pandey A | 2001 | Biomol Eng2001，18，5： | 1 |
| 7 | Vena caval transection during retroperioneo copic nephrectomy: report of the complication and review of the literature显示文摘 | McAllister M Bhayani S B Ong A | 2004 | J Urol2004，172，： | 1 |
| 8 | Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte-fibroblast coculture contributes to keloid pathogenesis 显示文摘 | Khoo YT Ong CT Mukhopadhyay A | 2006 | J Cell Physiol2006，208，2： | 1 |
| 9 | Synthesis, characterization and comparative study of nano- Ag--TiO2 against Gram- positive and Gram- negative bacteria under fluorescent light 显示文摘 | BARUDIN N H A SREEKANTAN S ONG M T | 2014 | Food Control2014，，46： | 1 |
| 10 | Thirty-day incidence and sixmonth clinical outcome of thrombotic stent occlusion after baremetal, sirolimus, or paclitaxel stent implantation 显示文摘 | Ong A T Hoye A Aoki J | 2005 | J Am Coll Cardiol2005，45，6： | 1 |
| 11 | Hybrid genetic algorithm and simulated annealing approach for the optimization of process plans for prismatic parts显示文摘 | LI W D ONG S K NEE A Y C | 2002 | International Journal of Product Research2002，40，8： | 1 |
| 12 | Preventing Mud Losses and Differential Sticking by Altering Effective Stress of Depleted Sands显示文摘 | Benaissa S Bachelor A Ong S | | SPE0，，： | 1 |
| 13 | Using real-time tissue elastography for breast lesion evaluation 显示文摘 | Raza S Odulate A Ong EM | 2010 | J Ultrasound Med2010，29，4： | 1 |
| 14 | Reactive pulsed laser deposition of CNx films 显示文摘 | Zhao X -A Ong C W Tsang Y C | 1995 | Appl Phys Lett1995，66，： | 1 |
| 15 | The B Subunit of Escherichia coli Heat-Labile Entero toxin Enhances CD8+ Cytotoxic-T-Lymphocyte Killing of Epstein-Barr Virus-Infected Cell Lines 显示文摘 | Ong Kong-Wee Wilson A Douglas Hirst | 2003 | Journal of Virology2003，77，7： | 1 |
| 16 | Thirty-day incidence and six-month clinical outcome of thrombotic stent occlusion after bare-metal, siroli- mus, or paclitaxel stent implantation显示文摘 | Ong AT Hoye A Aoki J | 2005 | J Am Coil Cardiol2005，45，6： | 1 |
| 17 | Water-to-air mass transfer of VOCs: Lahoratory-scale air sparging system显示文摘 | Chao K P Ong S K Protopapas A | 1998 | Journal of Envi?ronmental Engineering1998，124，11： | 1 |
| 18 | Long wave ultrasound may enhance bone regeneration by altering OPG/RANKL ratio in human osteo- blast-like cells显示文摘 | Maddi A Hal H Ong ST | 2006 | Bone2006，39，2： | 1 |
| 19 | Transepicondylar axes for femoral component rotation mighttproduce flexion asymmetry during total knee arthroplasty in knees with proximal tibia vara显示文摘 | Park IS Ong A Nam CH | | 0，，： | 1 |
| 20 | Orientation characterization and photoconductive properties of ethylenediamine bridged silicon phthalocyanine polymer thin film显示文摘 | SIM J H ONG B S REED C A | 1996 | Thin Solid Films1996，40，2： | 1 |
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