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| 1 | Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer显示文摘Inflammatory bowel diseases are characterised by inflammation that compromises the integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has evolved complex mechanisms to control and regulate bacterial interactions with the mucosal surface. Apical tight junction proteins are critical in the maintenance of epithelial barrier function and control of paracellular permeability. The characterisation of alterations in tight junction proteins as key players in epithelial barrier function in inflammatory bowel diseases is rapidly enhancing our understanding of critical mechanisms in disease pathogenesis as well as novel therapeutic opportunities. Here we give an overview of recent literature focusing on the role of tight junction proteins, in particular claudins, in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer. | Jonathan Landy Emma Ronde Nick English Sue K Clark Ailsa L Hart Stella C Knight Paul J Ciclitira Hafid Omar Al-Hassi | 2016 | World Journal of Gastroenterology2016，22，11： | 39 |
| 2 | 新一代渴望导管: 在肺的栓塞的处理的可行性显示文摘 AIM: To report our preliminary experience with a new generation aspiration catheter in the treatment of symptomatic pulmonary embolism(PE). METHODS: A retrospective database search for pulmonary artery embolectomy since introduction of the Pronto.035' and XL extraction catheter(Vascular Solutions, Minneapolis, MN) at our institution in 10/2009 was performed. Ten consecutive patients were identified in which the Pronto.035' or XL catheter was used between 01/2010 and 03/2013. All patients were referred for catheter based embolectomy due to contraindications to systemic lysis, or for being in such a critical clinical condition that immediate percutaneous treatment deemed warranted. The computed tomography(CT) right to left heart ratio as predictor for the severity of the PE was retrospectively evaluated on standard axial views. The difference between pre- and post-procedure pulmonary pressure measures was taken to assess the procedural effect.RESULTS: Extensive PE was confirmed angiographically in all patients. Measured right- to left ventricle(RV/LV) ratios were elevated beyond one in seven of the eight available CTs. Acute procedural success defined as clinical removal of visible thrombus and improvement in mean pulmonary artery pressure was seen in all recorded patients(n = 8), the mean pulmonary pressures declined from a median(range) of 35.5(19-46) to 23(10-37, P = 0.008) mmHg. Neither death nor other complications occurred intra- or immediately periprocedural, yet short term mortality within 30 d was found in 6 out of 9 patients, one patient was lost in follow up. The cause of death within 30 d in the 6 patients was identified as: Circulatory failure in direct connection with the PE(n = 2), stroke, sepsis, or succumbing to malignancy in a hospice setting(n = 2). CONCLUSION: Success in thrombus removal with improved pulmonary hypertension and systemic hypotension suggests this aspiration technique to be effective. Aspiration catheters should be part of further trials. | Wolf E Heberlein Mollie E Meek Omar Saleh James C Meek Shelly Y Lensing William C Culp | 2013 | World Journal of Radiology2013，5，11： | 2 |
| 3 | Polyphasic study of the spatial distribution of microorganisms in Mexican Pozol, a fer- mented maize dough, demonstrates the need for cultivation-inde- pendent methods to investigate traditional fermentations显示文摘 | Ampe F Ben Omar N Moizan C | 1999 | Ap- plied and Environmental Microbiology1999，，65： | 1 |
| 4 | Novel benzothiazole-2- carbomates as potential anthelmintieagents显示文摘 | Omar A M M E Ahmed I C | 2007 | Alexandria J of Pharm Scien2007，21，2： | 1 |
| 5 | Polyphasic study of the spatial distribution of microorganisms in Mexican Pozol, a fermented maize dough, demonstrates the need for cultivation-independent methods to investigate traditional fermentations 显示文摘 | Ampe F Ben Omar N Moizan C | 1999 | Applied and Environ Microbiol1999，65，： | 1 |
| 6 | Protein kinase B activity is required for the effects of insulin on lipid metabolism in adipocytes 显示文摘 | Berggreen C Gormand A Omar B | 2009 | Am J Physiol Endocrinol Metab2009，296，4： | 1 |
| 7 | Systematic re- view of oncological outcomes following surgical man agement of localised renal cancer显示文摘 | MacLennan S Imanmra M Lapitan M C Omar M I Lain T B Hilvano-Cabungcal A M | 2012 | Eur Urol2012，61，97： | 1 |
| 8 | Polyphasic study of the spatial distribution of microorganisms in Mexican pozol, a fermented maize dough demonsWates the need for cultivation-independent methods to investigate traditional fermentations 显示文摘 | AMPE F OMAR B N MO IZAN C | 1999 | Applied Environmental Microbiology1999，65，： | 1 |
| 9 | Filter-antenna module using substrate integrated waveguide cavities显示文摘 | OMAR A N JUAN C | 2011 | IEEE Anten- nas Wireless Propagation Letters2011，10，： | 1 |
| 10 | Polyphasie Study of the Spatial Distribution of Microorganisms in Mexican Pozol, a Fermented Maize Dough, Demonstrates the Need for Cultivation-Independent Methods To Investigate Traditional Fermentations显示文摘 | Ampe F Omar N B Moizan C | 1999 | Appl Environ Microbiol1999，65，12： | 1 |
| 11 | Improved protection from velogenic Newcastle disease virus challenge following multiple immunizations with plasmid DNA encoding for F and HN genes显示文摘 | Loke C F Omar A R Rsha A R | 2005 | Vet Immunol Immunopathol2005，106，3： | 1 |
| 12 | Metal - organic frameworks: A new class of porous materials 显示文摘 | Jesse L C Rowsell Omar M Y | 2004 | Microporous and Mesoporous Materials2004，73，12： | 1 |
| 13 | Web services architecture for user control and management of optical internet networks显示文摘 | Bill S Andrew B Omar C | 2004 | IEEE2004，92，9： | 1 |
| 14 | Polyphasic study of the spatial distribution of microorganisms in Mexican pozol, a fermented maize dough, demonstrates the need for cultivation independent methods to investigate traditional fermentations显示文摘 | AMPE F BEN OMAR N MOIZAN C | 1999 | Appl Environ Microbiol1999，，65： | 1 |
| 15 | A laboratory scale bioremediation of Tapis crude oil contaminated soil by bioaugmentation of Aeinetobaeter baumannii T30C 显示文摘 | Chang L K Ibrahim D Omar I C | 2011 | African Journal Of Microbiology Research2011，9，5： | 1 |
| 16 | Polyphasic study ofthe spalial dislribulion of microorgan -isms in mexican pozol, afermented maize dough,demonstrates the need for cultivation -independent methods to investigate traditional fermentations 显示文摘 | Ampe b\ Ben Omar N Moizan C el al | 1999 | Applied and Environmental Microbiology1999，，65： | 1 |
| 17 | Physicochemical Chamcterizatio- nand Formation of Glyphosate-laden Nano-emulsion for Herbicide Formulation 显示文摘 | Lim C J Basri M Omar D | 2012 | Industrial Crops and Products2012，36，1： | 1 |
| 18 | Physicochemical characterization and formation of glyphosate - laden nano - emulsion for herbicide formulation 显示文摘 | LIM C J BASRI M OMAR D | 2012 | Industrial Crops and Products2012，36，1： | 1 |
| 19 | Polyphasic study of the spatial distribution of microorganisms in Mexican pozol, a fermented maize dough, demonstrates the'need for cultivation-independent methods to investigate traditional fermentations 显示文摘 | Ampe F Ben Omar N Moizan C | 1999 | Appl Environ Microbiol1999，65，： | 1 |
| 20 | International Deception显示文摘 | Bond C F Omar A | 2000 | Personality and Social Psychology Bulletin2000，26，3： | 1 |
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