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| 1 | Update on Anti-Saccharomyces cerevisiae antibodies, anti-nuclear associated anti-neutrophil antibodies and antibodies to exocrine pancreas detected by indirect immunofluorescence as biomarkers in chronic inflammatory bowel diseases: Results of a multicent显示文摘AIM: Anti-Saccharomyces cerevisiae antibodies (ASCA), anti-nuclear associated anti-neutrophil antibodies (NANA) and antibodies to exocrine pancreas (PAB), are serological tools for discriminating Crohn’s disease (CrD) and ulcerative colitis (UC). Like CrD, coeliac disease (CoD) is an inflammatory bowel disease (IBD) associated with (auto) antibodies. Performing a multicenter study we primarily aimed to determine the performance of ASCA, NANA and PAB tests for IBD diagnosis in children and adults, and secondarily to evaluate the prevalence of these markers in CoD. METHODS: Sera of 109 patients with CrD, 78 with UC, 45 with CoD and 50 healthy blood donors were retrospectively included. ASCA, NANA and PAB were detected by indirect immunofluorescence (IIF). RESULTS: ASCA+/NANA- profile displayed a positive predictive value of 94.2% for CrD. Detection of ASCA was correlated with a more severe clinical profile of CrD and treatment of the disease did not influence their serum levels. ASCA positivity was found in 37.9% of active CoD.PAB were found in 36.7% CrD and 13.3% CoD patients and were not correlated with clinical features of CrD, except with an early onset of the disease. Fifteen CrD patients were ASCA negative and PAB positive. CONCLUSION: ASCA and PAB detected by IIF are specific markers for CrD although their presence does not rule out a possible active CoD. The combination of ASCA, NANA and PAB tests improves the sensitivity of immunological markers for CrD. Repeating ASCA, NANA, and PAB testing during the course of CrD has no clinical value. | S Desplat-Jégo C Johanet A Escande J Goetz N Fabien N Olsson E Ballot J Sarles JJ Baudon JC Grimaud M Veyrac P Chamouard RL Humbel | 2007 | World Journal of Gastroenterology2007，13，16： | 24 |
| 2 | 心房颤动——当今面临的挑战显示文摘在过去数年里,临床和科撞方面对心房颤动(房颤)的关注明显增加,有关这一论题的出版物数量迅速、稳定的增长就是证明。虽然已有一些新方法治疗遮一心律失常一但大多数房颤患者仍然不得不忍受这一心律失常,包括其不良后果和症状,房颤无疑是虽迫切需要有更好治疗方法的一种心律失常。为了达到这一目的,就需要更深刻地认识房颤的机制.以便开发直接影响这一基础病理生理机制的治疗措施。 | Olsson SB Hansson A Hedin E Holm M Ingemansson M Johansson R Meurling C Pehrson S Roijer A Yuan S 方丕华 | 1997 | 中华心律失常学杂志1997，1，1： | 3 |
| 3 | Lipopmtein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simavastatin Survival Study(4s)显示文摘 | Pederson J R Olsson A G Faergeman V | 1998 | Circulation1998，97，15： | 1 |
| 4 | Fundamental pathological lesions in vascular dementia显示文摘 | Brun A Engiuund E | 1996 | Acta Neurol Suppl1996，168，： | 1 |
| 5 | Intestinal colonization potential of Turbot ( Scophthalmus maximus ) and Dab (Limanda limanda )-associated bacteria with inhibitory effects against Vibrio anguillarum 显示文摘 | OLSSON J C WESTERDAHL A CONWAY P | 1992 | Appl Environ Microbiol1992，58，2： | 1 |
| 6 | The use of prostate specific antigen density to enhance the predictive value of intermediate levels of serum prostate specific antigen显示文摘 | BENSON M C WHANG I S OLSSON C A | 1992 | J Urol1992，147，： | 1 |
| 7 | Antisense oligodeoxynucleotide inhibition as a potent strategy in plant biology :identification of SUSIBA2 as a transcriptional activator in plant sugar signaling显示文摘 | SUN C X HOGLUND A S OLSSON H | 2005 | Plant J2005，44，1： | 1 |
| 8 | Wear behaviour of some low alloyed steels under combined impact/abrasion contact conditions显示文摘 | Sundstrom A Rendon J Olsson M | 2001 | Wear2001，250，1： | 1 |
| 9 | Wear behavior of some low alloyed steels under combined impact/abrasion contact conditions显示文摘 | SUNDSTROM A RENDON J OLSSON M | 2001 | Wear2001，，1： | 1 |
| 10 | Uptake of oxidized LDL by macrophages results in partial lysosomal enzyme inactivation and relocation显示文摘 | Li W Yuan X M Olsson A G | 1998 | Arterioscler Thromb Vasc Biol1998，18，2： | 1 |
| 11 | 显示文摘 | Sodergren S Hagfeldt A Olsson J | 1994 | Journal of Physical Chemistry1994，98，21： | 1 |
| 12 | Clinical severity of Mycoplasma pneumoniae(MP) infection is associated with bacterial load in oropharyngeal secretions but not with MP genotype显示文摘 | Nilsson A C Bjrkman P welinder - Olsson C | 2010 | BMC Infect Dis2010，10，： | 1 |
| 13 | 查看详情显示文摘 | Evilevitch A Rescic J J?nsson B Olsson U | | 0，，45： | 1 |
| 14 | Thoracic aortic aneurysm and dissection:increasing prevalence and improved outcomes reported in a nationwide population-based study of more than 14,000 cases from 1987 to 2002显示文摘 | Olsson C Thelin S St(a)hle E | | 0，，： | 1 |
| 15 | Eacteri- al colonization on titanium, hydroxyapatite, and amal- gam surface in vivo显示文摘 | LEONHARDT A OLSSON J DAHLEN G | 1995 | Dent Res1995，74，： | 1 |
| 16 | Fundamental pathological lesions in vascular dementia显示文摘 | Olsson Y Brun A Engiuund E | 1996 | Acta Neurol Scand Suppl1996，168，： | 1 |
| 17 | Intestinal colonization potential of turbot (Scophthalmus maximus) and dab (Limanda limanda) - associated bacteria with inhibitory effects against Vibrio anguillarum显示文摘 | Olsson J C Westerdahl A Conway P | 1992 | Applied and Environmental Microbiology1992，58，2： | 1 |
| 18 | The Hospital Anxiety and Depression Rating Scale: a cross-sectional study of psycho-metrics and case finding abilities in general practice显示文摘 | OlssOn I Mykletun A Dahl AA | 2005 | BMC Psychiatry2005，5，： | 1 |
| 19 | Reduced transforming growth factor betal production by mononuclear cells from patientswith active chronic idiopathic thrombocytopenic purpura显示文摘 | Andersson PO Olsson A Wadenvik H | 2002 | BrHaematol2002，116，4： | 1 |
| 20 | Charlson Comorbidity Index can add prognostic information to Rapid Emergency Medicine Score as a predictor of long-term mortality显示文摘 | Olsson T Terent A Lind L | 2005 | Eur J Emerg Med2005，12，5： | 1 |
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