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| 1 | Oxygen radical formation does not have an impact in the treatment of severe acute experimental pancreatitis using free cellular hemoglobin显示文摘瞄准:Microcirculatory 机能障碍和免费的氧激进分子是在严重尖锐胰腺炎的致病的重要因素。另外的氧交货可能每氧化提高类脂化合物,但是可以也改进胰腺的微循环。这研究在严重尖锐胰腺炎的一个啮齿类动物模型在氧激进分子和微循环的形成上估计免费细胞的牛的血红素的效果。方法:在尖锐胰腺炎 Wistar 老鼠的正式就职以后的十五分钟收到了任何一个 0.8 mL 牛的血红素(HBOC-200 ) , hydroxyethyl 淀粉(HES ) 或保证血量正常替换的生理盐水的 2.4 mL。在检查的 6 h 以后,胰每氧化产品 malondialdehyde (MDA ) 为类脂化合物的间接测量被切除并且很快处理了并且在胰腺的织物减少了谷胱甘肽(GSH ) 。结果:HBOC-200 的单个申请改进了胰腺的微循环并且显著地减少了组织病理学说的织物损坏。MDA 的织物集中没在这些组之间不同。另外,在 GSH 层次的差别都没被检测。结论:不过 HBOC-200 和 HES 的单个申请改进胰腺的微循环,在类脂化合物的没有差别每氧化,产品被检测。另外的氧供应(HBOC-200 ) 的有益的效果不每氧化导致提高的类脂化合物。 | Helge Kleinhans Oliver Mann Paulus G Schurr Jussuf T Kaifi Bente Hansen Jakob R Izbicki Tim Strate | 2006 | World Journal of Gastroenterology2006，12，18： | 6 |
| 2 | Strong prognostic value of nodal and bone marrow micro-involvement in patients with pancreatic ductal carcinoma receiving no adjuvant chemotherapy显示文摘AIM: To study the prognostic value of adjuvant chemo-therapy in patients with pancreatic, ductal adenocar-cinoma.METHODS: Lymph nodes from 106 patients with resectable pancreatic ductal adenocarcinoma were systematically sampled. A total of 318 lymph nodes classified histopathologically as tumor-free were examined using sensitive immunohistochemical assays. Forty-three (41%) of the 106 patients were staged as pT1/2, 63 (59%) as pT3/4, 51 (48%) as pN0, and 55 (52%) as pN1. The study population included 59 (56%) patients exhibiting G1/2, and 47 (44%) patients with G3 tumors. Patients received no adjuvant chemo- or radiation therapy and were followed up for a median of 12 (range: 3.5 to 139) mo.RESULTS: Immunostaining with Ber-EP4 revealed nodal microinvolvement in lymph nodes classified as “tumor free” by conventional histopathology in 73 (69%) out of the 106 patients. Twenty-nine (57%)of 51 patients staged histopathologically as pN0 had nodal microinvolvement. The five-year survival probability for pN0-patients was 54% for those without nodal microinvolvement and 0% for those with nodal microinvolvement. Cox-regression modeling revealed the independent prognostic effect of nodal microinvolvement on recurrence-free (relative risk 2.92, P = 0.005) and overall (relative risk 2.49, P = 0.009) survival.CONCLUSION: The study reveals strong and independent prognostic significance of nodal microinvolvement in patients with pancreatic ductal adenocarcinoma who have received no adjuvant therapy. The addition of immunohistochemical findings to histopathology reports may help to improve risk stratification of patients with pancreatic cancer. | Emre F Yekebas Dean Bogoevski Michael Bubenheim Bjrn-Christian Link Jussuf T Kaifi Robin Wachowiak Oliver Mann Asad Kutup Guellue Cataldegirmen Lars Wolfram Andreas Erbersdobler Christoph Klein Klaus Pantel Jakob R Izbicki | 2006 | World Journal of Gastroenterology2006，12，40： | 3 |
| 3 | Epidemiology of extended-spectrum beta-lactamase-producing Enterobacter isolates in a Spanish hospital during a 12-year period 显示文摘 | Canton R Oliver A Coque T M | 2002 | J Clin Microbiol2002，40，： | 3 |
| 4 | Hot Spares for DoS Attacks 显示文摘 | T Darmohray R Oliver | 2000 | The Magazine of USENIX and SAGE2000，25，4： | 1 |
| 5 | Deciphering the biology of My cobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole S T Brosch R Parkhill J Gamier T Churcher C Harris D Gordon S V Eiglmeier K Gas S Barry C E Tekaia F Badcock K Basham D Brown D Chillingworth T Cormor R Davies R Devlin K FeltweU T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Kroghs A McLean J Moule S Murphy L Oliver K Osborne J Quail M A Rafandream M A Rogers J Rutter S Seeger K Skelton J Squaraes R Squares S Sulston J E Taylo K Whitehead S Barrell B G | 1998 | Nature1998，393，： | 1 |
| 6 | Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells 显示文摘 | KUBO T HATTON R D OLIVER J | 2004 | J Immunol2004，173，12： | 1 |
| 7 | OMEGA EP high-energy petawatt laser: progress and prospects显示文摘 | D N Maywar J H Kelly L J Waxer S F B Morse I A Begishev J Bromage C Dorrer J L Edwards L Folnsbee M J Guardalben S D Jacobs R Jungquist T J Kessler R W Kidder B E Kruschwitz S J Loucks J R Marciante R L McCrory D D Meyerhofer A V Okishev J B Oliver G Pien | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 8 | Forest management effects on carabid beetle communities in coniferous and broadleaved forests: implications for conservation显示文摘 | Fuller R J Oliver T H Leather H R | 2008 | Insect Conservation and Diversity2008，1，： | 1 |
| 9 | Should We Delight the Customer 显示文摘 | Rust R T Oliver R L | 2000 | Journal of the Academy of Marketing Science2000，28，1： | 1 |
| 10 | Introducing muhicomponent reactions to polymer science:Passerini reactions of renewable monomers 显示文摘 | Oliver K Tommy T Michael A R M | 2011 | J Am Chem Soc2011，133，： | 1 |
| 11 | Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence 显示文摘 | Cole ST Brosch R Parkhill J Garnier T Churcher C Harris D Gordon SV Eiglmeier K Gas S Barry CE Tekaia F Badcock K Basham D Brown D Chillingworth T Connor R Davies R Devlin K Feltwell T Gentles S Hamlin N Holroyd S Hornsby T Jagels K Krogh A Mclean J Moule S Murphy L Oliver K Osborne J Quail MA Rajandream MA Rogers J Rutter S Seeger K Skelton J Squares R Squares S Sulston JE Taylor K Whitehead S Barrell BG | 1998 | Nature1998，393，6685： | 1 |
| 12 | Concurrent activation of highand low-level production processes in written composition显示文摘 | Olive T Kellogg R T | | 0，，04： | 1 |
| 13 | A new approach for measurement of cytotoxicity using colorimetric assay显示文摘 | Hussain R F Nouri A M Oliver R T | 1993 | J Immunol Methods1993，160，1： | 1 |
| 14 | Execution and pauses in writing narratives:Processing time,cognitive effort and typing skill显示文摘 | Alves R A Castro S L Olive T | | 0，，06： | 1 |
| 15 | Visible-light photoredox catalysis:dehalogenation of vicinal dibromo-,α-Halo-,andα,α-dibromocarbonyl compounds显示文摘 | Maji T Karmakar A Oliver R | 2011 | J Org Chem2011，76，： | 1 |
| 16 | Aggregate associated-C and physical protection in a tropical clayey soil under Malagasy conventional and no-tillage systems显示文摘 | Razafimbelo T M Albrecht A Oliver R | 2008 | Soil&Tillage Research2008，98，2： | 1 |
| 17 | A new approach for measurement of cytotoxicity using colorimetric assay 显示文摘 | Hussain R F Nouri A M Oliver R T | 1993 | J Immunol Methods1993，160，1： | 1 |
| 18 | Imaging and Analyzing in Response to New Product Advertising显示文摘 | OLIVER R L ROBERSON T S MITCHELL D J | 1993 | Journal of Advertising1993，，12： | 1 |
| 19 | Postoperative chemoradiotherapy for advanced squamous cell carcinoma of the head and neck:a systematic review with meta-analysis显示文摘 | Winquist E Oliver T Gilbert R | | 0，，01： | 1 |
| 20 | A gona-dotropin-releasing factor vaccine(Improvac)and porcine soma-totropin have synergistic and additive effects on growth performance in group-housed boars and gilts 显示文摘 | OLIVER W T M CCAULEY I HAR RELL R J | 2003 | Anita Sci2003，81，： | 1 |
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