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| 1 | Looking at sound: optoacoustics with all-optical ultrasound detection显示文摘Originally developed for diagnostic ultrasound imaging,piezoelectric transducers are the most widespread technology employed in optoacoustic(photoacoustic)signal detection.However,the detection requirements of optoacoustic sensing and imaging differ from those of conventional ultrasonography and lead to specifications not sufficiently addressed by piezoelectric detectors.Consequently,interest has shifted to utilizing entirely optical methods for measuring optoacoustic waves.All-optical sound detectors yield a higher signal-to-noise ratio per unit area than piezoelectric detectors and feature wide detection bandwidths that may be more appropriate for optoacoustic applications,enabling several biomedical or industrial applications.Additionally,optical sensing of sound is less sensitive to electromagnetic noise,making it appropriate for a greater spectrum of environments.In this review,we categorize different methods of optical ultrasound detection and discuss key technology trends geared towards the development of all-optical optoacoustic systems.We also review application areas that are enabled by all-optical sound detectors,including interventional imaging,non-contact measurements,magnetoacoustics,and nondestructive testing. | Georg Wissmeyer Miguel A.Pleitez Amir Rosenthal Vasilis Ntziachristos | 2018 | Light(Science & Applications)2018,7,1: | 9 |
| 2 | Transmission of vector vortex beams in dispersive media显示文摘Scattering phenomena affect light propagation through any kind of medium from free space to biological tissues.Finding appropriate strategies to increase the robustness to scattering is the common requirement in developing both communication protocols and imaging systems.Recently,structured light has attracted attention due to its seeming scattering resistance in terms of transmissivity and spatial behavior.Moreover,correlation between optical polarization and orbital angular momentum(OAM),which characterizes the so-called vector vortex beams(VVBs)states,seems to allow for the preservation of the polarization pattern.We extend the analysis by investigating both the spatial features and the polarization structure of vectorial optical vortexes propagating in scattering media with different concentrations.Among the observed features,we find a sudden swift decrease in contrast ratio for Gaussian,OAM,and VVB modes for concentrations of the adopted scattering media exceeding 0.09%.Our analysis provides a more general and complete study on the propagation of structured light in dispersive and scattering media. | Ilaria Gianani Alessia Suprano Taira Giordani NicolòSpagnolo Fabio Sciarrino Dimitris Gorpas Vasilis Ntziachristos Katja Pinker Netanel Biton Judy Kupferman Shlomi Arnong | 2020 | Advanced Photonics2020,2,3: | 7 |
| 3 | Functional optoacoustic neuro-tomography for scalable whole-brain monitoring of calcium indicators显示文摘Non-invasive observation of spatiotemporal activity of large neural populations distributed over entire brains is a longstanding goal of neuroscience.We developed a volumetric multispectral optoacoustic tomography platform for imaging neural activation deep in scattering brains.It can record 100 volumetric frames per second across scalable fields of view ranging between 50 and 1000 mm^(3) with respective spatial resolution of 35–200μm.Experiments performed in immobilized and freely swimming larvae and in adult zebrafish brains expressing the genetically encoded calcium indicator GCaMP5G demonstrate,for the first time,the fundamental ability to directly track neural dynamics using optoacoustics while overcoming the longstanding penetration barrier of optical imaging in scattering brains.The newly developed platform thus offers unprecedented capabilities for functional whole-brain observations of fast calcium dynamics;in combination with optoacoustics'well-established capacity for resolving vascular hemodynamics,it could open new vistas in the study of neural activity and neurovascular coupling in health and disease. | X Luís Deán-Ben Gali Sela Antonella Lauri Moritz Kneipp Vasilis Ntziachristos Gil G Westmeyer Shy Shoham Daniel Razansky | 2016 | Light(Science & Applications)2016,5,1: | 5 |
| 4 | Road vehicle emission factors development: A review显示文摘 | Vicente Franco Marina Kousoulidou Marilena Muntean Leonidas Ntziachristos Stefan Hausberger Panagiota Dilara | 2013 | Atmospheric Environment2013,,: | 2 |
| 5 | Effects of a catalysed and an additized particle filter on the emissions of a diesel passenger car operating on low sulphur fuels显示文摘 | Leonidas Ntziachristos Zissis Samaras Efthimios Zervas Pascal Dorlhène | 2005 | Atmospheric Environment2005,,27: | 1 |
| 6 | Looking and listening to light: the evolution of whole-body photonic imaging 显示文摘 | Ntziachristos V Ripoll J Wang LV | 2005 | Nature Biotechnology2005,23,3: | 1 |
| 7 | Looking and listening to light : The evolution of whole-body photonic imaging 显示文摘 | NTZIACHRISTOS V RIPOLL J WANG L H V | 2005 | Nature Biotechnology2005,23,3: | 1 |
| 8 | Frequency domain optoacoustic tomography using amplitudeand phase显示文摘 | MOHAJERANI P KELLNBERGER S NTZIACHRISTOS V | 2014 | Photoacoustics2014,2,3: | 1 |
| 9 | Imaging the Bio-Distribution of fluorescent probes using muhispectral Epi-Illumination cryoslicing imaging 显示文摘 | Sarantopoulos A Themelis G Ntziachristos V | 2011 | Molecular Imaging and Biology2011,13,5: | 1 |
| 10 | MRI-guided diffuse optical spectroscopy of malignant and benign breast lesions显示文摘 | Ntziachristos V Yodh AG Schnall MD | 2002 | Neo- plasia2002,4,4: | 1 |
| 11 | Charge-coupled-device based scanner for tomography of fluorescent near-infrared probes in turbid media 显示文摘 | Ntziachristos V Weissleder R | 2002 | Medical Physics2002,29,5: | 1 |
| 12 | Would near-infrared fluorescence signals propagate through large human organs for clinical studies 显示文摘 | Ntziachristos V Ripoll J Weissleder R | 2002 | Optics Letters2002,27,18: | 1 |
| 13 | Physicochemical and redox characteristics of particulate matter (PM) emitted from gasoline and diesel passenger cars显示文摘 | Michael D. Geller Leonidas Ntziachristos Athanasios Mamakos Zissis Samaras Debra A. Schmitz John R. Froines Constantinos Sioutas | 2006 | Atmospheric Environment2006,,36: | 1 |
| 14 | Looking and listening to light: the evolution of whole-body photonic imaging 显示文摘 | Ntziachristos V Ripoll J Wang LV | 2005 | Nat Biotechnol2005,23,3: | 1 |
| 15 | Shedding light ontolive molecular targets 显示文摘 | Weissleder R Ntziachristos V | 2003 | Nat Med2003,9,1: | 1 |
| 16 | Imager that combines near-infrared diffusive light and ultrasound 显示文摘 | Zhu Q Durduran T Ntziachristos V | 1999 | Optics Letters1999,24,15: | 1 |
| 17 | looking and listening to light: the evolution of whole-body photonic imaging 显示文摘 | Ntziachristos V Ripoll J Wang LV | 2005 | Nat Biotechnol2005,23,3: | 1 |
| 18 | Fluorescence molecular tomography resolves protease activity in vivo显示文摘 | Ntziachristos V Tung C H Bremer C | 2002 | Nat Med2002,22,8: | 1 |
| 19 | From Fly Wings to Targeted Cancer Therapies:A Centennial for Notch Signaling显示文摘 | Ntziachristos P Lim JS Sage J | 2014 | Cancer Cell2014,25,3: | 1 |
| 20 | Fluorescence imaging with near-infrared light:new technological advances that enable in vivo molecular imaging 显示文摘 | Ntziachristos V Bremer C Weissleder R | 2003 | Eur Radiol2003,13,1: | 1 |