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| 1 | Trans-arterial chemoperfusion for the treatment of liver metastases of breast cancer and colorectal cancer: Clinical results in palliative care patients显示文摘AIM To evaluate the clinical value and efficiency of transarterial chemoperfusion(TACP) in patients with liver metastases from breast cancer(BC) and colorectal cancer(CRC).METHODS We treated 36 patients with liver metastases of BC(n = 19, 19 females) and CRC(n = 17; 8 females, 9 males) with repeated TACP. The treatment interval was 4 wk. TACP was performed with gemcitabine(1000 mg/m2) and mitomycin(10 mg/m2), administered within 1 h after positioning the catheter tip in the hepatic artery. Before treatment, the size, location, tumour volume, vascularization and number of liver tumours were evaluated using magnetic resonance imaging(MRI). Tumour response was evaluated according to the Response Evaluation Criteria in Solid Tumors guidelines.RESULTS TACP using gemcitabine and mitomycin for metastases from CRC and BC was performed without any serious side effects. The follow-up MRI showed a therapeutic response in 84.2% of the BC patients-stable disease 47.4% and partial response 36.8%. A progression was seen in 15.8%.CRC patients showed a therapeutic response in 52.9% of cases. A progression of the disease was documented in 47.1% of the patients with CRC. These data show that TACP in patients with liver metastases of BC leads to a significantly better therapeutic response compared with CRC patients(P = 0.042). The median survival time was 13.2 mo for the BC patients, which is significantly longer than for CRC patients at 9.3 mo(P = 0.001).CONCLUSION TACP for liver metastases of BC appears to be a safe and effective palliative treatment with improved outcomes in comparison to patients with CRC. | Tatjana Gruber-Rouh Marcel Langenbach Nagy NN Naguib Nour-Eldin M Nour-Eldin Thomas J Vogl Stephan Zangos Martin Beeres | 2017 | World Journal of Clinical Oncology2017，8，4： | 7 |
| 2 | Predictive performance of three multivariate difficult tracheal intubation models:a double-blind,case-controlled study显示文摘 | Naguib M Scamman FL O'Sullivan C | 2006 | Anesth Analg2006，102，3： | 1 |
| 3 | Propofol: the challenges of formulation 显示文摘 | Baker MT Naguib M | 2005 | Anesthesiology2005，103，4： | 1 |
| 4 | Prevention of Paclitaxel-induced neuropathy through activation of the central cannabinoid type 2 receptor system显示文摘 | Naguib M Xu J J Diaz P | 2012 | Anesth Analg2012，114，5： | 1 |
| 5 | The effects of mela-tonin premedication on propofol and thiopental induction dose-re-sponse curves: a pospective, randomized, double blind study显示文摘 | Naguib M Samarkandi AH Moniem MA | 2006 | Anesth Analg2006，103，： | 1 |
| 6 | Adverse effects and drug interactions associated with local and regional anaesthesia显示文摘 | Naguib M Magboul MM Samarkandi AH | | 0，，04： | 1 |
| 7 | Chitosan Based Nanofibers, Review 显示文摘 | Elsabee M Z Naguib H F Morsi R E | 2012 | Materials Science and Engineering: C2012，32，7： | 1 |
| 8 | Prediction and char- acterization of MXene nanosheet anodes for non-lithium-ion batteries显示文摘 | Xie Y Dall'Agnese Y Naguib M | 2014 | ACS Nano2014，8，9： | 1 |
| 9 | From Theory to Practice AnOverview of MIMO Space-time coded wireless systems 显示文摘 | D Gesbert M Shafi D S Shiu P Smith A Naguib | 2003 | IEEE J Select Areas Communication2003，21，4： | 1 |
| 10 | Facial nerve neuromas:diagnosis and management显示文摘 | Saleh E Achilli V Naguib M | 1995 | Am J Otol1995，16，： | 1 |
| 11 | Large beamcolumn tests on concrete-filled composite tubes显示文摘 | Mirmian A Shahawy M Khoury C E and Naguib W | 2000 | ACI Structural Journal2000，97，2： | 1 |
| 12 | Prophylactic antiemetic therapy with ondansetron, tropiseton, granisetrom and metoclopramide in patients undergoing laparoscopic cholecystectomy: a randomized, double- blind comparison with placebo显示文摘 | Naguib M Bakry AKEL Khoshim MHB | 1996 | Can J Anaesth1996，43，3： | 1 |
| 13 | Sugammadex:another milestone in clinical neuromuscular pharmacology显示文摘 | Naguib M | | 0，，03： | 1 |
| 14 | Giant ceil tumor of the laterel skull base: a case report显示文摘 | Saleh EA Taibah AK Naguib M | 1994 | Otolaryngol Head Neck Surg1994，111，31： | 1 |
| 15 | Lower skullbase: anatomic study with surgical implications显示文摘 | Saleh E Naguib M Aristegui M | 1995 | Ann Otol Rhinol Laryngol1995，104，1： | 1 |
| 16 | Antinociceptive effects of spinal cholinesterase inhibition and isobolographic analysis of the interaction with mu and alpha 2 receptor systems显示文摘 | Naguib M Yaksh TL | 1994 | Anesthesiology1994，80，6： | 1 |
| 17 | Antioxodant activities of astaxanthin and related carotenoids显示文摘 | Naguib Y M A | 2000 | J Agric Food Chem2000，48，： | 1 |
| 18 | Lower skull base: An- atomic study with surgical implications 显示文摘 | Saleh E Naguib M Aristegui M | 1995 | Ann Otol Rhinol Laryngol1995，104，1： | 1 |
| 19 | Lower skull base:anatomic study with surgical implieations显示文摘 | Saleh E Naguib M Aristegui M | 1995 | Ann Otol Rhinol Laryngol1995，104，1： | 1 |
| 20 | Antioxidant activities of astaxanthin and related carotenoids显示文摘 | Naguib Y M A | 2000 | Journal of agricultural and food chemistry2000，48，4： | 1 |
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