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| 1 | Conventional versus drug-eluting bead transarterial chemoembolization:A better option for treatment of unresectable hepatocellular carcinoma显示文摘Transarterial chemoembolization(TACE) is a minimally invasive procedure involving intra-arterial catheter-based chemotherapy to selectively administer high doses of cytotoxic drugs to the tumor bed along with ischemic necrosis induced by arterial embolization.Chemoembolization forms the essential core of management in patients with hepatocellular carcinoma(HCC) who are not suitable for curative therapies such as transplantation,resection,or percutaneous ablation.TACE of hepatic cancer(s) has proven to be helpful in achieving local tumor control,and has supported the ability to prevent tumor progression,prolong patient life,and manage patient symptoms.Recent data have demonstrated that,in patients with single-nodule HCC ≤3 cm without vascular invasion,the 5-year overall survival with TACE was found to be comparable with hepatic resection and radiofrequency ablation.Used for several years,Lipiodol continues to play a vital role as a tumor-seeking and radiopaque drug delivery vector in interventional oncology.Efforts have been made to enhance the administration of chemotherapeutic agents to tumors.Compared with conventional TACE,drug-eluting bead TACE is a fairly new drug delivery embolization technique that permits fixed dosing and has the ability to provide sustained release of anticancer agents over a period of time.The present review discusses the basic procedure of TACE and its properties,and the effectiveness of conventional and drug-eluting bead chemoembolization systems currently available or presently undergoing clinical evaluation. | Murtuza Razi Gu Jianping He Xu Mohammed Jameeluddin Ahmed | 2021 | Journal of Interventional Medicine2021，4，1： | 9 |
| 2 | Comparison of tumor response following conventional versus drug-eluting bead transarterial chemoembolization in early-and very early-stage hepatocellular carcinoma显示文摘Objective:To compare the safety of conventional transarterial chemoembolization(cTACE)vs drug-eluting bead TACE(DEB-TACE)in very early-and early-stage hepatocellular carcinoma(HCC).Methods:Data of patients with early-and very early-stage HCC treated with cTACE or DEB-TACE were evaluated retrospectively in this study.A total of 40 patients were included,20 treated with cTACE and 20 with DEB-TACE.The cTACE and DEB-TACE groups were comprised of 80%and 75%males,while there were 20%females in cTACE group and 25%in Deb-TACE group respectively.The mean age of patients in cTACE group was 57.43+5.6 years,while it was 56.4+5.5 years in DEB-TACE group.All patients had liver status of Child–Pugh Class A and a score≤7 in Child-Pugh class type B in very early-(stage 0)or early-phase(stage A)stages according to the Barcelona Clinic Liver Cancer(BCLC)system.Results:The Child-Pugh class degradation in the cTACE group was slightly higher than that in the DEB-TACE group.Serious complications like peritumoral parenchymal ischemia were observed in 4 patients in the cTACE group and 5 in the DEB-TACE group.Localized bile duct dilation was seen in 2 patients in the cTACE group and 6 in the DEB-TACE group.No significant variation in serious complications between the two groups was established in localized bile duct dilatation.Other minor complications noted were liver failure,liver abscess,liver infarction,acute cholecystitis,biliary tree necrosis,and mortality.Further,no substantial variation in tumor response between the groups was reported immediately and 1-year post-procedural assessment.Conversion rate to other treatment modalities such as surgical resection,radiofrequency ablation(RFA),or swap between cTACE and DEB-TACE was substantially higher in the DEB-TACE group(40%)than in the cTACE group(10%)at the 1-year completion period of the study.Conclusion:In terms of tumor response,the DEB-TACE group showed a better response,to some extent,as an initial therapy for HCC in the early stages as compared to the cTACE group,and DEB-TACE also exhibited better clinical efficacy in patients with HCC. | Murtuza Razi Syed Safiullah Jianping Gu Xu He Mustafa Razi Jie Kong | 2022 | Journal of Interventional Medicine2022，5，1： | 3 |
| 3 | Online tuning of a steady state crude distillation unit model for real time applications显示文摘 | Dhaval J Dave Murtuza Z Dabhiya Satyadev S V K | 2003 | Journal of Process Control2003，13，3： | 1 |
| 4 | Cell transplantation for the treatment of acute myocardial infarction using vascular endothelial growth factor-expressing skeletal myoblasts显示文摘 | Suzuki K Murtuza B Smolenski RT | 2001 | Circulation2001，104，121： | 1 |
| 5 | 显示文摘 | Jiang Q Plew D V Murtuza S | 1996 | Tetrahedron Lett1996，37，6： | 1 |
| 6 | Enhanced effect of myocardial gene transfection by VP22-mediated intercellular protein transport显示文摘 | SUZUKI K MURTUZA B BRAND N J | 2004 | J Mol Cell Cardiol2004，36，4： | 1 |
| 7 | Intracoronary infusion of skeletal myoblasts improves cardiac function in doxorubicin-induced heart failure显示文摘 | Suzuki K Murtuza B Suzuki N | 2001 | Circulation2001，104，： | 1 |
| 8 | Cell transplantation for the treatment of acute myocardial infarction using vascular endothelial growth factor-expressing skeletal myoblasts显示文摘 | Suzuki K Murtuza B Smolenski RT | 2001 | Circulation2001，104，1： | 1 |
| 9 | Enhanced effect of myocardial gene transfection by VP22-mediated intercellular protein transport显示文摘 | Suzuki K Murtuza B Brand NJ | 2004 | J Mol Cell Cardiog2004，36，4： | 1 |
| 10 | Heat shock protein 72 enhances manganese superoxide dismutase activity during myocardial ischemia-reperfusion injury, associated with mitochondrial protection and apoptosis reduction 显示文摘 | Suzuki K Murtuza B Sammut IA | 2002 | Circulation2002，106，121： | 1 |
| 11 | New tantalum-based catalyst system for the selective trimerization of ethene to 1-hexene显示文摘 | ANDES C HARKINS S B MURTUZA S | 2001 | J Am Chem Soc2001，123，30： | 1 |
| 12 | Effect of tube size on performance of a fixed-film tubular bioreactor for conversion of hydrogen sulfide to elemental sulfur 显示文摘 | Murtuza A S Paul F H | 2003 | Water Research2003，37，： | 1 |
| 13 | Intracoronary infusion of skeletal myoblasts improves cardiac function in doxorubicin-induced heart failure 显示文摘 | Suzuki K Murtuza B Suzuki N | 2001 | Circulation2001，104，1： | 1 |
| 14 | Transplantation of skeletal myoblasts secreting an IL-1 inhibitor modulates adverse remodeling in infarcted murine myocardium显示文摘 | Murtuza B Suzuki K Bou-Gharios G | 2004 | Proc Natl Acad Sci USA2004，101，12： | 1 |
| 15 | Effect of tube size on performance of a fixed-fixed tubular bioreactor for conversion of hydrogen sulfide to elemental sulfur显示文摘 | Murtuza A Hen Shaw P F | 2003 | Water Research2003，37，： | 1 |
| 16 | Micro-and nanoscale control of the cardiac stem cell niche for tissue fabrication显示文摘 | Murtuza B Nichol JW Khademhosseini A | 2009 | Tissue Eng Part B Rev2009，15，4： | 1 |
| 17 | Pediatric heart transplanta- tion for congenital and restrictive cardiomyopathy 显示文摘 | Murtuza B Fenton M Bureh M | 2013 | Ann Thorac Surg2013，95，5： | 1 |
| 18 | Online tuning of a steady state crude distillation unit model for real time applications 显示文摘 | Dhaval J D Murtuza Z D Satydev S V K | 2003 | Journal of Process Control2003，，13： | 1 |
| 19 | Three- dimensional face recognition in the presence of facial expressions: An annotated deformable model approach 显示文摘 | Kakadiaris I Passalis G Toderici G Murtuza N | 2007 | IEEE Transactions on Pattern Analysis and Machine Intelligence (S0162-8828)2007，29，： | 1 |
| 20 | Cell transplantation for the treatment of acute myocardial infarction using vascular endothelial growth factor-expressing skeletal myoblasts显示文摘 | Suzuki K Murtuza B Smolenaki RT | 2001 | Circulation2001，104，121： | 1 |
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