|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Efficacy of peroral endoscopic myotomy vs other achalasia treatments in improving esophageal function显示文摘AIM: To assess and compare the esophageal function after peroral endoscopic myotomy(POEM) vs other conventional treatments in achalasia.METHODS: Chart review of all achalasia patients who underwent POEM, laparoscopic Heller myotomy(LHM) or pneumatic dilation(PD) at our institution between January 2012 and March 2015 was performed. Patient demographics, type of achalasia, prior treatments, pre- and post-treatment timed barium swallow(TBE) and high-resolution esophageal manometry(HREM) findings were compared between the three treatment groups. Patients who had both pre- and 2 mo posttreatment TBE or HREM were included in the final analysis. TBE parameters compared were barium column height, width and volume of barium remaining at 1 and 5 min. HREM parameters compared were basal lower esophageal sphincter(LES) pressures and LES-integrated relaxation pressures(IRP). Data are presented as mean ± SD, median [25th, 75 th percentiles] or frequency(percent). Analysis of variance, KruskalWallis test, Pearsons χ~2 test and Fishers Exact tests were used for analysis.RESULTS: A total of 200 achalasia patients were included of which 36 underwent POEM, 22 underwent PD and 142 underwent LHM. POEM patients were older(55.4 ± 16.8 years vs 46.5 ± 15.7 years, P = 0.013) and had higher BMI than LHM(29.1 ± 5.9 kg/m^2 vs 26 ± 5.1 kg/m^2, P = 0.012). More number of patients in POEM and PD groups had undergone prior treatments compared to LHM group(72.2% vs 68.2% vs 44.3% respectively, P = 0.003). At 2 mo post-treatment, all TBE parameters including barium column height, width and volume remaining at 1 and 5 min improved significantly in all three treatment groups(P = 0.01 to P < 0.001) except the column height at 1 min in PD group(P = 0.11). At 2 mo post-treatment, there was significant improvement in basal LES pressure and LES-IRP in both LHM(40.5 mm Hg vs 14.5 mm Hg and 24 mm Hg vs 7.1 mm Hg respectively, P < 0.001) and POEM groups(38.7 mm Hg vs 11.4 mm Hg and 23.6 mm Hg vs 6.6 mm Hg respectively, P < 0.001). However, when the efficacy of three treatments were compared to each other in terms of improvement in TBE or HREM parameters at 2 mo, there was no significant difference(P > 0.05).CONCLUSION: POEM, PD and LHM were all effective in improving esophageal function in achalasia at shortterm. There was no difference in efficacy between the three treatments. | Madhusudhan R Sanaka Umar Hayat Prashanthi N Thota Ramprasad Jegadeesan Monica Ray Scott L Gabbard Neha Wadhwa Rocio Lopez Mark E Baker Sudish Murthy Siva Raja | 2016 | World Journal of Gastroenterology2016，22，20： | 7 |
| 2 | The six minute walk test accurately estimates mean peak oxy- gen uptake显示文摘 | ROSS R M MURTHY J N WOLLAK I D | 2010 | BMC Pulm Med2010，10，31： | 1 |
| 3 | Clinico- pathologic study of dextran sulfate sodium experimental mu- rine colitis显示文摘 | COPPER H S MURTHY S N SHAH R S | 1993 | Lab Invest1993，69，： | 1 |
| 4 | Catalytic Vapor Phase Reduction of Nitrobenzene to Aniline in Fluidized Beds显示文摘 | Deshpande P K Kuloor N R | 1963 | Chemical Age of India1963，14，： | 1 |
| 5 | pH-sensitive polymers that enhance intracellular drug delivery in vivo显示文摘 | Kyriakides T R Cheung C Y Murthy N | 2002 | J Control Release2002，78，13： | 1 |
| 6 | Hollow self-inducing impellers for gas-liquid-solid dispersion: Experimental and computational study显示文摘 | Murthy B N Kasundra R B Joshi J B | 2008 | Chemical Engineering Journal2008，141，1： | 1 |
| 7 | Extraction of molybdenum from spent catalyst by salt-roasting 显示文摘 | Kar B B Murthy B V R Misra V N | 2005 | In- ternational Journal of Mineral Processing2005，76，3： | 1 |
| 8 | Hollow self-inducing impellers for gas-liquid-solid dispersion: Experimental and computational study显示文摘 | Murthy B N Kasundra R B Joshi J B | 2008 | Chemical Engineering Journal2008，141，13： | 1 |
| 9 | External Prestressing Technique for Strengthening of Prestressed Concrete Structural Components显示文摘 | SAIBABU S LAKSHMANAN N MURTHY A R C | | 0，，02： | 1 |
| 10 | Studies on the antioxidant activity of pomegranate peel and seed ex tracts using in vitro modes 显示文摘 | Singh R P Chidambara Murthy K N Jaya-prkasha G K | 2002 | Journal of Agricuhural and Food Chemistry2002，，50： | 1 |
| 11 | Managed care, deficit financing, and agegate health care expenditure in the United States: a cointegration analysis 显示文摘 | MURTHY N R OKUNADE A A | 2000 | Health Care Manag Sci2000，3，4： | 1 |
| 12 | Studies on the antioxidant activity of pomegranate (Punica granatum) peel and seed extracts using in vitro models显示文摘 | SINGH R P CHIDAMBARA MURTHY K N JAYAPRAKASHA G K | 2002 | Journal of Agricultural and Food Chemistry2002，50，1： | 1 |
| 13 | Clinicopathologic study of dextran sulfate sodium experimental murine colitis显示文摘 | Cooper H S Murthy S N Shah R S | 1993 | Lab Invest1993，69，2： | 1 |
| 14 | Synthesis of copper sulphide and copper nanopartic1es with microemulsion method显示文摘 | SOLANKI J N SENGUPTA R MURTHY Z V P | 2010 | Solid State Sciences2010，12，： | 1 |
| 15 | Adaptive stick-slip friction and backlash compensation using dynamic fuzzy logic system显示文摘 | Suraneni S Kar I N Murthy O V R | 2005 | Applied Soft Computing2005，6，1： | 1 |
| 16 | Clinicopathologic study of dextran sulfate sodium experimental murine colitis显示文摘 | Cooper H S Murthy S N Shah R S | 1993 | Laboratory Investigation1993，69，2： | 1 |
| 17 | Studies on the antioxidant activity of pomegranate (Punica granatum)peel and seed extracts using in vitro models显示文摘 | Singh R P Chidambara Murthy K N Jayaprakasha G K | 2002 | Journal of Agicultural and Food Chemistry2002，50，1： | 1 |
| 18 | Stress sensitivity of inductance in NiCuZn ferrites 显示文摘 | REDDY N R RAMANA M V RAJITHA G RAJAGOPAL E SICAKUMAR K V MURTHY V R K | 2005 | J Magn Magn Mater2005，292，： | 1 |
| 19 | Aggregate health care expenditure in the United States:Evidence from cointegration tests显示文摘 | Murthy N R V Ukpolo V | | 0，，08： | 1 |
| 20 | Product warranty man- agement - I : A taxonomy for warranty policies 显示文摘 | BLISCHKE W R MURTHY D N P | 1992 | European Journal of Operational Research1992，62，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员