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| 1 | Radial artery access site complications during cardiac procedures,clinical implications and potential solutions: The role of nitric oxide显示文摘Percutaneous coronary intervention for the treatment of coronary artery disease is most commonly performed in the UK through the radial artery,as this is considered to be safer than the femoral approach.However,despite improvements in technology and techniques,complications can occur.The most common complication,arterial spasm,can cause intense pain and,in some cases,procedural failure.The incidence of spasm is dependent on several variables,including operator experience,artery size,and equipment used.An antispasmolytic cocktail can be applied to reduce spasm,which usually includes an exogenous nitric oxide(NO)donor(glyceryl trinitrate).NO is an endogenous local vasodilator and therefore is a potential target for anti-spasm intervention.However,systemic administration can result in unwanted side-effects,such as hypotension.A method that adopts local delivery of NO might be advantageous.This review article describes the mechanisms involved in radial artery spasm,discusses the advantages and disadvantages of current strategies to reduce spasm,and highlight the potential of NO-loaded nanoporous materials for use in this setting. | Emma M Coghill Timothy Johnson Russell E Morris Ian L Megson Stephen J Leslie | 2020 | World Journal of Cardiology2020，12，1： | 4 |
| 2 | Regulation of Wnt/β-catenin signaling by herpesviruses显示文摘The Wnt/β-catenin signaling pathway is instrumental in successful differentiation and proliferation of mammalian cells. It is therefore not surprising that the herpesvirus family has developed mechanisms to interact with and manipulate this pathway. Successful coexistence with the host requires that herpesviruses establish a lifelong infection that includes periods of latency and reactivation or persistence. Many herpesviruses establish latency in progenitor cells and viral reactivation is linked to host-cell proliferation and differentiation status. Importantly, Wnt/β-catenin is tightly connected to stem/progenitor cell maintenance and differentiation. Numerous studies have linked Wnt/β-catenin signaling to a variety of cancers, emphasizing the importance of Wnt/β-catenin pathways in development, tissue homeostasis and disease. This review details how the alpha-, beta-, and gammaherpesviruses interact and manipulate the Wnt/β-catenin pathway to promote a virus-centric agenda. | Kevin J Zwezdaryk Joseph A Combs Cindy A Morris Deborah E Sullivan | 2016 | World Journal of Virology2016，5，4： | 2 |
| 3 | Early infant male circumcision:Systematic review,risk-benefit analysis,and progress in policy显示文摘AIM To determine whether recent evidence-based United States polices on male circumcision(MC) apply to comparable Anglophone countries,Australia and New Zealand.METHODS Articles in 2005 through 2015 were retrieved from PubM ed using the keyword 'circumcision' together with 36 relevant subtopics.A further PubM ed search was performed for articles published in 2016.Searches of the EMBASE and Cochrane databases did not yield additional citable articles.Articles were assessed for quality and those rated 2+ and above according to the Scottish Intercollegiate Grading System were studied further.The most relevant andrepresentative of the topic were included.Bibliographies were examined to retrieve further key references.Randomized controlled trials,recent high quality systematic reviews or meta-analyses(level 1++ or 1+ evidence) were prioritized for inclusion.A risk-benefit analysis of articles rated for quality was performed.For efficiency and reliability,recent randomized controlled trials,metaanalyses,high quality systematic reviews and large welldesigned studies were used if available.Internet searches were conducted for other relevant information,including policies and Australian data on claims under Medicare for MC.RESULTS Evidence-based policy statements by the American Academy of Pediatrics(AAP) and the Centers for Disease Control and Prevention(CDC) support infant and later age male circumcision(MC) as a desirable public health measure.Our systematic review of relevant literature over the past decade yielded 140 journal articles that met our inclusion criteria.Together,these showed that early infant MC confers immediate and lifelong benefits by protecting against urinary tract infections having potential adverse long-term renal effects,phimosis that causes difficult and painful erections and 'ballooning' during urination,inflammatory skin conditions,inferior penile hygiene,candidiasis,various sexually transmissible infections in both sexes,genital ulcers,and penile,prostate and cervical cancer.Our risk-benefit analysis showed that benefits exceeded procedural risks,which are predominantly minor,by up to 200 to 1.We estimated that more than 1 in 2 uncircumcised males will experience an adverse foreskin-related medical condition over their lifetime.Wide-ranging evidence from surveys,physiological measurements,and the anatomical location of penile sensory receptors responsible for sexual sensation strongly and consistently suggested that MC has no detrimental effect on sexual function,sensitivity or pleasure.United States studies showed that early infant MC is cost saving.The evidence supporting early infant MC has further strengthened since the positive AAP and CDC reviews.CONCLUSION Affirmative MC policies are needed in Australia and New Zealand.Routine provision of accurate,unbiased education,and access in public hospitals,will maximize health and financial benefits. | Brian J Morris Sean E Kennedy Alex D Wodak Adrian Mindel David Golovsky Leslie Schrieber Eugenie R Lumbers David J Handelsman John B Ziegler | 2017 | World Journal of Clinical Pediatrics2017，6，1： | 2 |
| 4 | Effect of small alloying additions on behavior of rapidly solidified Cu-Cr alloys 显示文摘 | BATAWI E MORRIS D G MORRIS M A | 1990 | Materials Science and Technology1990，6，： | 2 |
| 5 | Indolicidin,a novel bactericidal tridecapeptide amide from neutrophils显示文摘 | Selsted M E Novotny M J Morris W L | 1992 | J Biol Chem1992，267，： | 2 |
| 6 | Viral-mediated gene therapy for spinal cord injury(SCI) from a translational neuroanatomical perspective显示文摘Repairing spinal cord injury(SCI)is one of the most challenging endeavours currently faced by neuroscientists.One promising therapeutic avenue to reverse this once considered permanent condition is gene therapy,however progress has been hampered by the anatomica intricacy of the spinal cord itself as well as by the sheer complexity of the molecular cascades of events that take place in the injured cord. | Andrew P Tosolini Renée Morris | 2016 | Neural Regeneration Research2016，11，5： | 2 |
| 7 | Pathology grading of colon cancer surgical resection and its association with survival:a retrospective observational study显示文摘 | West NP Morris E J Rotimi O | | 0，，09： | 2 |
| 8 | Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress 显示文摘 | Park DS Morris E J Stefanis L | 1998 | J Neurosci1998，18，3： | 1 |
| 9 | Rehtionship between cellulolytic activity and adhesion to cellulose in Ruminococcus Atbus 显示文摘 | Morris E J Cole O J | 1987 | J Gen Microbiol1987，133，： | 1 |
| 10 | Fast Pattern Matching in String显示文摘 | Knuth D E Morris J H Pratt V R | 1977 | SIAM Journal on Computing1977，6，6： | 1 |
| 11 | Mycophenolic acid morphlinoethyester (RS- 61443) is a new immunosupperessant that prevents and halts heart allograft rejection by selective inhibition of T- and B- cell purine synthesis显示文摘 | Hoyt E G Murphy M P | 1990 | Transplantation Proc1990，22，6： | 1 |
| 12 | BBCA1:BARD1 induce the formation of conjugated ubiquitin structures,dependent on K6 of ubiquitin,in cells during DNA replication and repair显示文摘 | Solomon E | 2004 | Hum Molec Genet2004，13，8： | 1 |
| 13 | Nonrandom distribution of interspersed repeat elements in the BCR and ABL1 genes and its relation to breakpoint cluster regions 显示文摘 | Wells E Morris CM | 2001 | Genes Chromosomes Cancer2001，32，2： | 1 |
| 14 | Electrical conduction models for isotropically conductive adhesive joints显示文摘 | MORRIS J E | 1997 | IEEE Transactions on Components Package Manufacturing Technology1997，20，1： | 1 |
| 15 | Ventricular arrhythmia in patients with hypertensive left ventricular hypertrophy显示文摘 | McLenachan JM Hendeson E Morris KI | 1987 | N Engl med1987，317，13： | 1 |
| 16 | Formed and preformed metabolites: facts and comparisons 显示文摘 | Pang K S Morris M E Sun H F | 2008 | J Pharm Pharmacol2008，60，10： | 1 |
| 17 | 显示文摘 | Morris D E Chandrachood M R Sinha A P B | 1991 | Physica C1991，175，： | 1 |
| 18 | Electrical conduction models for isotropically conductive adhesive joints显示文摘 | Li Li James E Morris | 1997 | IEEE Trans Comp Packg Manuf Technol1997，，： | 1 |
| 19 | Molecular genetic analysis of FIH-1, FH, and SDHB candidate tumour suppressor genes in renal cell carcinoma显示文摘 | Morris MR Maina E Morgan NV | 2004 | J Clin Pathol2004，57，7： | 1 |
| 20 | Activity and structure of hydrotreating Ni,Mo,and Ni-Mo sulfide catalysts supported on γ-Al2O3-USY zeolite 显示文摘 | Dien L Nishijima A Morris D E | 1999 | J Catalysis1999，188，： | 1 |
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