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| 1 | Prognostic value of increased carbohydrate antigen in patients with heart failure显示文摘AIM:To study the prognostic value of carbohydrateantigen 125(CA125) and whether it adds prognostic information to N-terminal pro-brain natriuretic peptide(NT-proBNP) in stable heart failure(HF) patients.METHODS:The predictive value of CA125 was retrospectively assessed in 156 patients with stable HF remitted to the outpatient HF unit for monitoring from 2009 to 2011.Patients were included in the study if they had a previous documented episode of HF and received HF treatment.CA125 and NT-proBNP concentrations were measured.The independent association between NT-proBNP or CA125 and mortality was assessed with Cox regression analysis,and their combined predictive ability was tested by the integrated discrimination improvement(IDI) index.RESULTS:The mean age of the 156 patients was 72 ± 12 years.During follow-up(17 ± 8 mo),27 patients died,1 received an urgent heart transplantation and 106 required hospitalization for HF.Higher CA125 values were correlated with outcomes:58 ± 85 KU/L if hospitalized vs 34 ± 61 KU/L if not(P < 0.05),and 94 ± 121 KU/L in those who died or needed urgent heart transplantation vs 45 ± 78 KU/L in survivors(P < 0.01).After adjusting for propensity scores,the highest risk was observed when both biomarkers were elevated vs not elevated(HR = 8.95,95%CI:3.11-25.73; P < 0.001) and intermediate when only NT-proBNP was elevated vs not elevated(HR = 4.15,95%CI:1.41-12.24; P < 0.01).Moreover,when CA125 was added to the clinical model with NT-proBNP,a 4%(P < 0.05) improvement in the IDI was found.CONCLUSION:CA125 > 60 KU/L identified patients in stable HF with poor survival.Circulating CA125 level adds prognostic value to NT-proBNP level in predicting HF outcomes. | Ana B Méndez Jordi Ordonez-Llanos Andreu Ferrero Mariana Noguero Teresa Mir Josefina Mora Antoni Bayes-Genis Sònia Mirabet Juan Cinca Eulàlia Roig | 2014 | World Journal of Cardiology2014，6，4： | 13 |
| 2 | Gut homing receptors on CD8 T cells are retinoic acid dependent and not maintained by liver dendritic or stellate cells显示文摘 | Eksteen B Mora JR Haughton EL | 2009 | Gastroenterology2009，137，1： | 1 |
| 3 | Adoption and use of precision agriculture technologies in the sugarcane industry of Sao Paulo state,Brazil显示文摘 | SILVA C B DE MORAES A F D MOLIN J P | 2011 | Precision Agric2011，12，： | 1 |
| 4 | A randomized controlled trial comparing vaginal misoprostol versus Foley catheter plus oxytocin for labor induction 显示文摘 | MORAES FILHO O B ALBUQUERQUE R M CECATYI J G | 2010 | Acta Obstetricia et Gyriecologica Scandinavica2010，89，8： | 1 |
| 5 | Vertical root fractures and dentin defects: effects of root canal preparation, filling, and mechanical cycling显示文摘 | SANGOI B M MORAES R D A ROSA R A D | 2012 | J Endod2012，38，8： | 1 |
| 6 | Anisotropic wave propagation through finite-difference grids 显示文摘 | Igd H Mora P Riollet B | 1995 | Geophysics1995，60，4： | 1 |
| 7 | Clays and oxide minerals as catalysts and nanocatalysts in Fenton-like reactions -Areview显示文摘 | Garrido-Ramirez E G B K G Theng M L Mora | 2010 | Applied Clay Science2010，47，34： | 1 |
| 8 | A Revised Catalog of the Mite Family Phytoseiidae显示文摘 | De Moraes G J McMurtry J A Denmark H A & Campos C B | 2004 | Zootaxa2004，434，： | 1 |
| 9 | Association ofLDL cholesterol,non-HDL cholesterol,and apolipoprotein Blevels with risk of cardiovascular events among patients treatedwith statins:a meta-analysis显示文摘 | Boekholdt S M Arsenault B J Mora S | 2012 | JAMA2012，307，12： | 1 |
| 10 | Asso- ciation of LDL cholesterol, non- HDL cholesterol, and apoli- poprotein B levels with risk of cardiovascular events among- patients treated with statins : A Meta- analysis 显示文摘 | BOEKHOLDT S M ARSENAULT B J MORA M | 2012 | JAMA2012，307，12： | 1 |
| 11 | Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells显示文摘 | Iwata M Eksteen B | 2006 | Science2006，314，： | 1 |
| 12 | Constitutive activation of STAT3 in human prostate tumors and cell lines:direct inhibition of STAT3 signaling induces apoptosis of prostate cancer cells 显示文摘 | Mora L B Buettner R Seigne J | 2002 | Cancer Res2002，62，22： | 1 |
| 13 | Rigorous modeling and simulation of molecular distillators: development of a simulator under conditions of non ideality of the vapor phase显示文摘 | Batistella C B Moraes E B Maciel M R W | 2000 | Computers and Chemicals Engineering2000，24，： | 1 |
| 14 | Clays and oxide minerals as catalysts and nanocatalysts in Fenton- like re- actions-A review显示文摘 | Garrido- Ramirez E G Theng B K G Mora M L | 2010 | Applied Clay Science2010，47，34： | 1 |
| 15 | Segment-constrainedregression tree estimation of forest stand height from very highspatial resolution panchromatic imagery over a boreal environment显示文摘 | MORA B WULDER M A WHITE J C | 2010 | Remote Sensing of Environment2010，114，11： | 1 |
| 16 | Association of LDL chalesteral, non- HDL chalesteral, and apalipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis显示文摘 | BOEKHOLDT SM ARSENAULT B J MORA S | 2012 | JAMA2012，307，12： | 1 |
| 17 | Constitutive activation of STAT3 in human prostate tumors and cell lines:direct inhibition of STAT3 signaling induces apoptosis of prostate cancer cells 显示文摘 | Mora L B Buettner R Seigne J | 2002 | Cancer Res2002，62，22： | 1 |
| 18 | Accuracy of staggered 3-D finite-difference grids for anisotropic wave propagation显示文摘 | Igel H Riollet B Mora P | 1992 | Expanded Abstracts of 62^nd Annual Internat SEG Meeting1992，，： | 1 |
| 19 | Impact of high-dose atorvastatin therapy and clinical risk factors on incident aortic valve stenosis in patients with cardiovascular disease (from TNT, IDEAL, and SPARCL) 显示文摘 | Arsenauh B J Boekholdt SM Mora S | 2014 | Am J Cardiol2014，113，8： | 1 |
| 20 | Aryltetralin lignans inbit plant growth by affecting the formation of mitotic microtubular organizing centers pesticide显示文摘 | Oliva A Moraes R M Watson S B | 2002 | Biochemistry and Physiology2002，72，： | 1 |
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