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| 1 | Endoscopic stenting for inoperable malignant biliary obstruction: A systematic review and meta-analysis显示文摘AIM: To analyze through meta-analyses the benefits of two types of stents in the inoperable malignant biliary obstruction.METHODS: A systematic review of randomized clinical trials(RCT) was conducted, with the last update on March 2015, using EMBASE, CINAHL(EBSCO), MEDLINE, LILACS/CENTRAL(BVS), SCOPUS, CAPES(Brazil), and gray literature. Information of the selected studies was extracted in sight of six outcomes: primarily regarding dysfunction, complication and reintervention rates; and secondarily costs, survival, and patency time. The data about characteristics of trial participants, inclusion and exclusion criteria and types of stents were also extracted. The bias was mainly assessed through the JADAD scale. This meta-analysis was registered in the PROSPERO database by the number CRD42014015078. The analysis of the absolute risk of the outcomes was performed using the software Rev Man, by computing risk differences(RD) of dichotomous variables and mean differences(MD) of continuous variables. Data on RD and MD for each primary outcome were calculated using the MantelHaenszel test and inconsistency was qualified and reported in χ2 and the Higgins method(I2). Sensitivity analysis was performed when heterogeneity was higher than 50%, a subsequent assay was done and other findings were compiled. Student's t-test was used for the comparison of weighted arithmetic means regarding secondary outcomes.RESULTS: Initial searching identified 3660 studies; 3539 were excluded through title, repetition, and/or abstract, while 121 studies were fully assessed and were excluded mainly because they did not compare self-expanding metal stents(SEMS) and plastic stents(PS), leading to thirteen RCT selected, with 13 articles and 1133 subjects meta-analyzed. The mean age was 69.5 years old, that were affected mostly by bile duct(proximal) and pancreatic tumors(distal). The preferred SEMS diameter used was the 10 mm(30 Fr) and the preferred PS diameter used was 10 Fr. In the metaanalysis, SEMS had lower overall stent dysfunction compared to PS(21.6% vs 46.8%, P < 0.00001) and fewer re-interventions(21.6% vs 56.6%, P < 0.00001), with no difference in complications(13.7% vs 15.9%, P = 0.16). In the secondary analysis, the mean survival rate was higher in the SEMS group(182 d vs 150 d, P < 0.0001), with a higher patency period(250 d vs 124 d, P < 0.0001) and a lower cost per patient(4193.98 vs 4728.65 Euros, P < 0.0985).CONCLUSION: SEMS are associated with lower stent dysfunction, lower re-intervention rates, better survival, and higher patency time. Complications and costs showed no difference. | Leonardo Zorrón Pu Eduardo Guimaraes Hourneaux de Moura Wanderley Marques Bernardo Felipe Iankelevich Baracat Ernesto Quaresma Mendonca AndréKondo Gustavo Oliveira Luz Carlos Kiyoshi Furuya Júnior Everson Luiz de Almeida Artifon | 2015 | World Journal of Gastroenterology2015，21，47： | 10 |
| 2 | Creatine supplementation improves muscular perform- ance in older women 显示文摘 | Gotshalk LA Kraemer W J Mendonca MA | 2008 | Eur J Appl Physiol2008，102，： | 1 |
| 3 | Impacts of embanking on the soil-vagetation relationships in a floodplain ecosystem of a pre-alpine river 显示文摘 | MENDONCA SANTOS M L GUENAT C THEVOZ C BUREAU F VEDY J C | 1997 | Global Ecology and Biogeography Letters1997，6，： | 1 |
| 4 | Creatine supplementation improves muscular perform- ance in older women 显示文摘 | Gotshalk LA Kraemer W J Mendonca MA | 2008 | Eur J Appl Physiol2008，102，： | 1 |
| 5 | Modeling of droplet dynamic and thermal behavior during spray deposition 显示文摘 | MAHESH N S MENDONCA J MURALIDHARA M K | 2003 | Indian Academy of Sciences2003，26，3： | 1 |
| 6 | Isolation and characteri-zation of four microsatellite loci in the tidewater goby(Eu- cyclogobius newberryi)显示文摘 | Mendonca H Smith J Brinegar C | 2001 | Marine Biotechnology2001，3，： | 1 |
| 7 | An elasto-static FEM/BEM analysis of vertically loaded raft and piled raft foundation显示文摘 | Mendonca A V Paiva J B | 2003 | Engineering Analysis with Boundary Elements2003，27，9： | 1 |
| 8 | When social issues become strategic 显示文摘 | BONINI S MENDONCA L OPPENHEIM J | 2006 | The Mckinsey Quarterly2006，，2： | 1 |
| 9 | Acute renal failure in the ICU:risk factors and outcome evaluation by SOFA score显示文摘 | Mendonca A Vincent J L Suter P M | 2000 | Intensive Care Med2000，26，： | 1 |
| 10 | A comparative eval- uation of methodologies for water content determination in green coffee显示文摘 | Mendonca J C F Franca A S Oliveira L S | 2007 | LWT Food Science and Technology2007，40，7： | 1 |
| 11 | Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units:results of a multicentric,prospective study显示文摘 | VINCENT J L De MENDONCA A CANTRAINE F | 1998 | Crit Care Med1998，26，： | 1 |
| 12 | Impact of large scale wind power integration on small signal stability显示文摘 | Mendonca A Lopes J A P | 2005 | Future Power Systems2005，，10： | 1 |
| 13 | Effect of irradiation on the quality of turkey ham during storage显示文摘 | ZHU M J LEE E J MENDONCA A | 2003 | Meat Science2003，66，1： | 1 |
| 14 | Shear capacity of short anchor bolts and welded studs: a literature review显示文摘 | Klingner R E Mendonca J A | 1982 | ACI Journal1982，79，5： | 1 |
| 15 | Client-side selection of replicated web Services:An empirical assessment显示文摘 | Mendonca N C Silva J A F Anido R O | 2008 | The Journal of Systems and Software2008，81，8： | 1 |
| 16 | The essential role of zinc in growth显示文摘 | BRAND-NETO J STEFAN V MENDONCA B B | 1995 | Nutrition Research1995，15，3： | 1 |
| 17 | An elastostatic FEM/BEM analysis of vertically loaded raft and piled raftfoundation显示文摘 | MENDONCA A V PAIVA J B | 2003 | Engineering Analysis with BoundaryElements2003，27，9： | 1 |
| 18 | Treatment of textile wastewater by heterogeneous Fenton process using a new composite Fe2O3/carbon 显示文摘 | Dantas T L P Mendonca V P Jose H J | 2006 | Chemical Engineering Journal2006，118，5： | 1 |
| 19 | Effect of vitam in E and selenium on resistance to oxidative stress in chicken superficial pectoralis muscle显示文摘 | Avanzo J Mendonca J C Pugine S | 2001 | Com-parative Biochemistry and Physiology Part C2001，129，16： | 1 |
| 20 | Effect of calcium intake on urinary oxalate excretion in calcium stone-forming patients显示文摘 | NISHIURA J L MARTINI L A MENDONCA C O G | 2002 | Brazilian J Med Bio Res2002，35，： | 1 |
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