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	题名	作者	年代	出处	被引量
1	Relevance of MUC1 mucin variable number of tandem repeats polymorphism in H pylori adhesion to gastric epithelial cells显示文摘AIM:To evaluate the influence of MUC1 mucin variable number of tandem repeats (VNTR) variability on H pylori adhesion to gastric cells. METHODS: Enzyme linked immunosorbent assay (ELISA)-based adhesion assays were performed to measure the adhesion of different H pylori strains (HP26695 and HPTx30a) to gastric carcinoma cell lines (GP202 and MKN45) and GP202 clones expressing recombinant MUC1 with different VNTR lengths. RESULTS: Evaluation of adhesion results shows that H pylori pathogenic strain HP26695 has a significantly higher (P < 0.05) adhesion to all the cell lines and clones tested, when compared to the non-pathogenic strain HPTx30a. Bacteria showed a significantly higher (P < 0.05) adhesion to the GP202 cell line, when compared to the MKN45 cell line. Furthermore, both strains showed a significantly higher (P < 0.05) adhesion to GP202 clones with larger MUC1 VNTR domains. CONCLUSION: This work shows that MUC1 mucin variability conditions H pylori binding to gastric cells. The extent of bacterial adhesion depends on the size of theMUC1 VNTR domain. The adhesion is further dependent on bacterial pathogenicity and the gastric cell line. MUC1 mucin variability may contribute to determine H pylori colonization of the gastric mucosa.	Natália R Costa Nuno Mendes Nuno T Marcos Celso A Reis Thomas Caffrey Michael A Hollingsworth Filipe Santos-Silva	2008	World Journal of Gastroenterology2008，14，9：	4
2	High levels of the onco-Protein GFI-1 accelerate T-cell proliferation and inhihbit Activation induced T-cell death in Jurkat T-cells显示文摘	Karsunky H Mende I Schmidt T	2002	Oncogene2002，21，10：	1
3	MRI finding in Rasmussen's en- cephalitis显示文摘	Mendes D Moreno T Sd G et aI	2012	Acta Med Port2012，25，1：	1
4	Handgrip strength at ad- mission and time to discharge in medical and surgical inpatients 显示文摘	Mendes J Azevedo A Amaral T F	2013	Journal of Parenteral and Enteral Nutrition2013，，：	1
5	Familial hyperc- holesterolemia: Molecular characterization of possible cases from the Azores Islands (Portugal) 显示文摘	Cymbron T Mendes P Ramos A	2014	Meta Gene2014，14，2：	1
6	Osteoradionecrosis of the jaws as a side effect of radiotherapy of head and neck tumour patients-a report of a thirty year retrospective review显示文摘	Reuther T SchustervT Mende U	2003	Int J Oral Maxillofac Surg2003，32，4：	1
7	Osteoradionecrosis of the jaws as a side effect of radiotherapy of head and neck tumour patients--a report of a thirty-year retrospective review 显示文摘	Reuther T Schuster T Mende U	2003	Int J Oral Maxillofac Surg2003，32，3：	1
8	CD133 is a modifier of hematopoietic progenitor frequencies but is dispensable for the maintenance of mouse hematopoietic stem cells显示文摘	Arndt K Grinenko T Mende N		Proc Nat/ Acad Sci U S A0，110，14：	1
9	Load-independent parameters of diastolic and systolic function by speckle tracking and tissue doppler in hemodialysis patients 显示文摘	Mendes L Ribeiras R Adragao T	2008	Rev Port Cardiol2008，27，9：	1
10	Neighborhood topologies in fully-in-formed and best-of-neighborhood particle swarms显示文摘	KENNEDY J MENDES t	2006	IEEE Transactions on Systems Man and Cybernetics:Part C Applications and Reviews2006，36，4：	1
11	From AR to c - Met: androgendeprivation leads to a signaling pathway switch in prostate cancer cells 显示文摘	Liu T Mendes DE Berkman CE	2013	lnt J 0ncol2013，43，4：	1
12	Hand-foot syndrome associated with short infusions of combination chemotherapy with gecitabine and vinorelbine显示文摘	Laack E Mende T Knuffmann C	2001	Ann Oncol2001，12，12：	1
13	Membrane ultrafiltration of crude soybean oil显示文摘	Alicieo T V R Mendes E S	2002	Desalination2002，，148：	1
14	Osteoradionecrosis of the jaws as a side effect of radiotherapy of head and neck tumour pa- tients-a report of a thirty year retrospective review 显示文摘	Reuther T Schuster T Mende U	2003	Int J Oral Maxillofac Surg2003，32，：	1
15	Incidence and risk factors of major toxicity associated to firstline antituberculosis drugs for latent and active tuberculosis during a period of 10 years 显示文摘	CASTRO A T MENDES M FREITAS S	2015	Rev Port Pneumol2015，21，3：	1
16	Current tools for the identification of mi RNA genes and their targets显示文摘	Mendes N D Freitas A T Sagot M F	2009	Nucleic Acids Research2009，37，8：	1
17	The genetic environment of the cfr gene and the presence of other mechanisms account for the very high linezolid resistance of Staphylococcus epidermidis isolate 426-3147L 显示文摘	Lamarre J Mendes RE Szal T	2013	Antimicrob Agents Chemother2013，57，3：	1
18	Involvement of adiponectin and leptin in breast cancer: clinical and in vitro studies显示文摘	Jarde T Caldefie - Chezet F Goncalves - Mendes N	2009	Endocrine - related Cancer2009，16，4：	1
19	Crystallization and toxicology of T34: a major toxin from Florida/s red tide orgnism (Ptychodiscus brevis)显示文摘	Baden D G Mende T J Licher W	1980	Toxicon1980，19，：	1
20	Fear of falling and fall-related efficacy in relationship to functioning among community-living elders显示文摘	TINETTI M E MENDES de LEON C F DOUCETTE J T	1994	J Gerontol1994，49，3：	1

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