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| 1 | MicroRNAs as possible biomarkers for diagnosis and prognosis of hepatitis b- and c-related-hepatocellularcarcinoma显示文摘Aim of the present review is to summarize the current knowledge about the potential relationship between mi RNAs and hepatitis B virus(HBV)-hepatitis C virus(HCV) related liver diseases. A systematic computerbased search of published articles, according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis Statement, was performed to identify relevant studies on usefulness of serum/plasma/urine mi RNAs, as noninvasive biomarkers for early detection of HBV and HCV-induced hepatocellular carcinoma(HCC) development, as well as for its prognostic evaluation. The used Medical Subject Headings terms and keywords were: 'HBV', 'HCV', 'hepatocellular carcinoma', 'micro RNAs', 'mi RNAs', 'diagnosis', 'prognosis', 'therapy', 'treatment'. Some serum/plasma mi RNAs, including mi R-21, mi R-122, mi-125a/b, mi R-199a/b, mi R-221, mi R-222, mi R-223, mi R-224 might serve as biomarkers for early diagnosis/prognosis of HCC, but, to date, not definitive results or well-defined panels of mi RNAs have been obtained. More well-designed studies, focusing on populations of different geographical areas and involving larger series of patients, should be carried out to improve our knowledge on the potential role of mi RNAs for HCC early detection and prognosis. | Sirio Fiorino Maria Letizia Bacchi-Reggiani Michela Visani Giorgia Acquaviva Adele Fornelli Michele Masetti Andrea Tura Fabio Grizzi Matteo Zanello Laura Mastrangelo Raffaele Lombardi Luca Di Tommaso Arrigo Bondi Sergio Sabbatani Andrea Domanico Carlo Fabbri Paolo Leandri Annalisa Pession Elio Jovine Dario de Biase | 2016 | World Journal of Gastroenterology2016，22，15： | 25 |
| 2 | Metabolism of tissue macrophages in homeostasis and pathology显示文摘Cellular metabolism orchestrates the intricate use of tissue fuels for catabolism and anabolism to generate cellular energy and structural components.The emerging field of immunometabolism highlights the importance of cellular metabolism for the maintenance and activities of immune cells.Macrophages are embryo-or adult bone marrow-derived leukocytes that are key for healthy tissue homeostasis but can also contribute to pathologies such as metabolic syndrome,atherosclerosis,fibrosis or cancer.Macrophage metabolism has largely been studied in vitro.However,different organs contain diverse macrophage populations that specialize in distinct and often tissue-specific functions.This context specificity creates diverging metabolic challenges for tissue macrophage populations to fulfill their homeostatic roles in their particular microenvironment and conditions their response in pathological conditions.Here,we outline current knowledge on the metabolic requirements and adaptations of macrophages located in tissues during homeostasis and selected diseases. | Stefanie K.Wculek Gillian Dunphy Ignacio Heras-Murillo Annalaura Mastrangelo David Sancho | 2022 | Cellular & Molecular Immunology2022，19，3： | 9 |
| 3 | Occupational exposure to vinyl chloride and liver diseases显示文摘Portal hypertension,liver fibrosis,and angiosarcoma of the liver(ASL)have been reported among workers exposed to vinyl chloride monomer(VCM)since the 1970s.In 2007,the International Agency for Research on Cancer established the association of VCM with hepatocellular carcinoma(HCC),though only on the basis of the few cases available.Thereafter,recent reports from the United States cohort and a European sub-cohort of vinyl chloride workers provided compelling evidence of a strong association between cumulative VCM exposure and HCC risk.Further areas of research include the risk of liver cancer at lower levels of exposure and different patterns of risk of ASL and HCC with the time since exposure.The evidence of interaction between VCM exposure and other known liver carcinogens such as alcohol and chronic viral infection provides clues for the health surveillance of exposed workers.Notably,also the risk of VCM-associated chronic liver disease is modulated by alcohol consumption,viral infection,and genetic polymorphism.A counter-intuitive finding from cohort studies of exposed workers is the lower mortality from liver cirrhosis with respect to the general population;this can be attributed to the healthy worker effect and to the selection of liver cancer as the cause of death in the presence of concomitant chronic liver disease.Studies designed to overcome these intricacies confirmed an association between cumulative VCM exposure and the risk of liver cirrhosis. | Ugo Fedeli Paolo Girardi Giuseppe Mastrangelo | 2019 | World Journal of Gastroenterology2019，25，33： | 2 |
| 4 | Some statistical process control methods for autocorrelated data显示文摘 | Montgomery D C Mastrangelo C M | 1991 | Journal of Quality Technology1991，23，： | 1 |
| 5 | Polycyclic aromatic hydr-ocarbons and cancer in man显示文摘 | Mastrangelo G Fadda E Marzia V | 1996 | Environ Health Perspect1996，104，11： | 1 |
| 6 | A new wideband high frequency channel simulation system 显示文摘 | MASTRANGELO John F LEMMON John J VOGLER Lewis E | 1997 | IEEE Transactions on Communications1997，45，1： | 1 |
| 7 | Analysis of end user securi- ty behaviors显示文摘 | Stanton J Stam K Mastrangelo P | 2005 | Computers & Security2005，24，2： | 1 |
| 8 | Physiological and biomechanical analysis of treadmill walking up various gradients in men and women显示文摘 | Kang J Chaloupa E C Mastrangelo M A | 2002 | European Journal of Applied Physiology2002，86，6： | 1 |
| 9 | Recipient outcome following living donor kidney transplantation using kidneys procured laparoscopically显示文摘 | KS Reddy M Mastrangelo T D Johnston | 2003 | Clin Transplant2003，17，9： | 1 |
| 10 | Spontaneous Ruptureof the Stomach in a Healthy Adult Man After Sodium BicarbonateIngestion显示文摘 | Michael R Mastrangelo MD Edward W | 1984 | Ann Intern Med1984，101，5： | 1 |
| 11 | Assessment of nutri- tional status in children with chronic kidney disease and on dialysis 显示文摘 | Mastrangelo A Paglialonga F Edefonti A | 2014 | Pediatr Nephrol2014，29，8： | 1 |
| 12 | Epidemiologic evidence of cancer risk in textile industry workers: a review and update显示文摘 | G Mastrangelo U Fedeli E Fadda | 2002 | Toxicology and industrial health2002，18，4： | 1 |
| 13 | Laparoscopic common bile duct exploration显示文摘 | KaraBeth B Moore Gina L Adrales Michael J Mastrangelo | 2004 | Current Surgery2004，，3： | 1 |
| 14 | Pattern and determinants of hospitalization during heat waves: an ecologic study显示文摘 | Mastrangelo G Fedeli U Visentin C | 2007 | BMC Public Health2007，7，： | 1 |
| 15 | Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases 显示文摘 | Mastrangelo P Mathews P M Chishti MA | 2005 | Proc Natl Acad Sci USA2005，102，25： | 1 |
| 16 | A new wideband high frequency channel simulation system 显示文摘 | MASTRANGELO J F LEMMON J J | 1997 | IEEE Transactions on Communication1997，45，1： | 1 |
| 17 | Systemic therapy in malanoma显示文摘 | Mastrangelo MJ | 1998 | J Surg Oncol1998，14，4： | 1 |
| 18 | Surface Micromachined Paraffin-actuated Microvalve显示文摘 | Carlen E T Mastrangelo C H | 2002 | J Microelectromech Syst2002，11，： | 1 |
| 19 | Bodily self and schizophrenia: The loss of implicit self-body knowledge显示文摘 | Francesca Ferri Francesca Frassinetti Francesca Mastrangelo Anatolia Salone Filippo Maria Ferro Vittorio Gallese | 2012 | Consciousness and Cognition2012，，3： | 1 |
| 20 | Dynamic relocal- ization of histone macroI-I2A1 from centrosomes to inactive X chro- mosomes during X inactivation 显示文摘 | Rasmussen T P Mastrangelo M A Eden A | 2000 | The Journal of Cell Biology2000，150，5： | 1 |
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