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| 1 | Significant association between ABO blood group and pancreatic cancer显示文摘AIM:To evaluate whether the ABO blood group is related to pancreatic cancer risk in the general population of the United States.METHODS:Using the University of Pittsburgh's clinicalpancreatic cancer registry,the blood donor database from our local blood bank (Central Blood Bank),and the blood product recipient database from the regional transfusion service (Centralized Transfusion Service) in Pittsburgh,Pennsylvania,we identified 274 pancreatic cancer patients with previously determined serological ABO blood group information.The ABO blood group frequency was compared between these patients and 708842 individual,community-based blood donors who had made donations to Pittsburgh's Central Blood Bank between 1979 and 2009.RESULTS:The frequency of blood group A was statistically significantly higher amongst pancreatic cancer patients compared to its frequency amongst the regional blood donors [47.63% vs 39.10%,odds ratio (OR)=1.43,P=0.004].Conversely,the frequency of blood group O was significantly lower amongst pancreatic cancer patients relative to the community blood donors (32.12% vs 43.99%,OR=0.60,P=0.00007).There were limited blood group B (n=38) and AB (n=17) pancreatic cancer patients;the overall P trend value comparing patient to donor blood groups was 0.001.CONCLUSION:The ABO blood group is associated with pancreatic cancer risk.Future studies should examine the mechanism linking pancreatic cancer risk to ABO blood group. | Julia B Greer Mark H Yazer Jay S Raval M Michael Barmada Randall E Brand David C Whitcomb | 2010 | World Journal of Gastroenterology2010，16，44： | 10 |
| 2 | Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis显示文摘 | Katrin M Sjoquist Bryan H Burmeister B Mark Smithers John R Zalcberg R John Simes Andrew Barbour Val Gebski | 2011 | Lancet Oncology2011，，7： | 4 |
| 3 | Tolllike receptor2 m ediates lipopolysaccharides induced cellular signaling显示文摘 | Yan R B Mark M R Gray A | 1998 | Nature1998，395，： | 2 |
| 4 | Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury显示文摘 | Caudrillier Axelle Kessenbrock Kai Gilliss Brian M Nguyen John X Marques Marisa B Monestier Marc Toy Pearl Werb Zena Looney Mark R | 2012 | EN2012，，7： | 2 |
| 5 | Gastroesophageal reflux disease after diagnostic endoscopy in the clinical setting显示文摘AIM: To investigate the outcome of patients with symptoms of gastroesophageal reflux disease (GERD) referred for endoscopy at 2 and 6 mo post endoscopy. METHODS: Consecutive patients referred for upper endoscopy for assessment of GERD symptoms at two large metropolitan hospitals were invited to participate in a 6-mo non-interventional (observational) study.The two institutions are situated in geographically and socially disparate areas. Data collection was by selfcompletion of questionnaires including the patient assessment of upper gastrointestinal disorders symptoms severity and from hospital records. Endoscopic finding using the Los-Angeles classification, symptom severity and it's clinically relevant improvement as change of at least 25%, therapy and socio-demographic factors were assessed. RESULTS: Baseline data were available for 266 patients and 2-mo and 6-mo follow-up data for 128 and 108 patients respectively. At baseline, 128 patients had erosive and 138 non-erosive reflux disease. Allmost all patient had proton pump inhibitor (PPI) therapy in the past. Overall, patients with non-erosive GERD at the index endoscopy had significantly more severe symptoms as compared to patients with erosive or even complicated GERD while there was no difference with regard to medication. After 2 and 6 mo there was a small, but statistically significant improvement in symptom severity (7.02 ± 5.5 vs 5.9 ± 5.4 and 5.5 ± 5.4 respectively); however, the majority of patients continued to have symptoms (i.e. , after 6 mo 81% with GERD symptoms). Advantaged socioeconomic status as well as being unemployed was associated with greater improvement. CONCLUSION: The majority of GORD patients receive PPI therapy before being referred for endoscopy even though many have symptoms that do not sufficiently respond to PPI therapy. | Nora B Zschau Jane M Andrews Richard H Holloway Mark N Schoeman Kylie Lange William CE Tam Gerald J Holtmann | 2013 | World Journal of Gastroenterology2013，19，16： | 2 |
| 6 | J Colloid InterfSci 显示文摘 | Mattson J S Mark H B Malbin M D | 1969 | 31(1): 1161969，31，1： | 1 |
| 7 | Toll-like receptor 2 mediates lipoplysaccharide-induced celluar signalling 显示文摘 | Yang R B Mark M R Gray A | 1998 | Nature1998，395，6699： | 1 |
| 8 | The novel DPP-4 inhibitors linagliptin and BI 14361 reduce infarct size after mvocardial ischemia/reperfusion in rats显示文摘 | Hocher B Sharkovska Y Mark M | 2013 | Int J Cardiol2013，167，： | 1 |
| 9 | C-rective protein:a criti-cal update显示文摘 | Mark B Gideon M | 2003 | Clin Invest2003，111，： | 1 |
| 10 | Good strategy instructors are Constructivists 显示文摘 | PRESSLEY M HARRIA K R MARKS M B | 1992 | Educational Psychology Review1992，4，1： | 1 |
| 11 | Ontology with Human Sub jects Testing: an Empirical Investigation of Geo graphic Categories显示文摘 | Smith B Mark D M | 2001 | International Journal of Geo graphical Information Science2001，15，59： | 1 |
| 12 | Mechanisms of resistance to the cytotoxic effects of oxysterols in human leukemic cells显示文摘 | Claudia C Gregorio-King Tamara Gough Gavin J Van Der Meer Jane B Hosking Caryll M Waugh Janet L McLeod Fiona Mc Collier Mark A Kirkland | 2004 | Journal of Steroid Biochemistry and Molecular Biology2004，，3： | 1 |
| 13 | Prospective study of perceived stress in cardiac patients显示文摘 | Brummett B H Babyak M A Mark D B | 2004 | Ann Behav Med2004，27，1： | 1 |
| 14 | Choice of methodology for assessing genetic impacts of environmental stressors:Polymorphism and reproducibility of RAPD and AFLP fingerprints显示文摘 | Mark J B Susan L A Bernie M 2001 | 2001 | Ecotoxicology2001，10，： | 1 |
| 15 | PTEN in- duced vascular endothelial growth fator secretion in head and neck squamous cell carcinoma显示文摘 | Mark G S Leigh A B Megan M K | 2005 | Biochem Biophys Res Commun2005，331，3： | 1 |
| 16 | Application of the analytical hierarchy process to establish health care waste management systems that minimise infection risks in developing countries 显示文摘 | Alan C Brent David E C Rogers Tsaletseng S M Ramabitsa-Siimane Mark B Rohwer | 2007 | European Journal of Operational Research 1812007，，： | 1 |
| 17 | A school out- break of Norwalk-like virus: evidence for airborne trans- mission显示文摘 | Marks P J Vipond I B Regan F M | 2003 | Epidemiol Infect2003，131，1： | 1 |
| 18 | Natural-language Spatial Relations between Linear and Area Objects:The Topology and Metric of English-language Terms显示文摘 | SHARIFF A R B M EGENHOFER M J MARK D M | 1998 | International Journal of Geographical Information Science1998，12，3： | 1 |
| 19 | Step returns in threshold public goods: A meta -analysis and experimental analysis显示文摘 | Croson R T A M B Marks | 2000 | Experi- mental Economics2000，2，： | 1 |
| 20 | Using plasma transforming growth factor beta-1 during radiotherapy to select patients for dose escalation显示文摘 | Anscher M S Marks L B Shafman T D | | 0，，17： | 1 |
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