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357篇 您的检索式:作者名="Mark R W"
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1Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: An association study in New Zealand Caucasians and meta-analysis显示文摘AIM:To investigate the association of macrophage migration inhibitory factor(MIF)promoter polymorphisms with inflammatory bowel disease(IBD)risk.METHODS:One thousand and six New Zealand Caucasian cases and 540 Caucasian controls were genotyped for the MIF SNP-173G>C(rs755622)and the repeat polymorphism CATT5-8(rs5844572)using a predesigned TaqMan SNP assay and capillary electrophoresis,respectively.Data were analysed for single site and haplotype association with IBD risk and phenotype.Meta-analysis was employed,to assess cumulative evidence of association of MIF-173G>C with IBD.All published genotype data for MIF-173G>C in IBD were identified using PubMed and subsequently searching the references of all PubMed-identified studies.Imputed genotypes for MIF-173G>C were generated from the Wellcome Trust Case Control Consortium(and National Institute of Diabetes and Digestive and Kidney Diseases).Separate meta-analyses were performed on Caucasian Crohn’s disease(CD)(3863 patients,6031controls),Caucasian ulcerative colitis(UC)(1260 patients,1987 controls),and East Asian UC(416 patients and 789 controls)datasets using the Mantel-Haenszel method.The New Zealand dataset had 93%power,and the meta-analyses had 100%power to detect an effect size of OR=1.40 atα=0.05,respectively.RESULTS:In our New Zealand dataset,single-site analysis found no evidence of association of MIF polymorphisms with overall risk of CD,UC,and IBD or disease phenotype(all P values>0.05).Haplotype analysis found the CATT5/-173C haplotype occurred at a higher frequency in New Zealand controls compared to IBD patients(0.6 vs 0.01;P=0.03,OR=0.22;95%CI:0.05-0.99),but this association did not survive bonferroni correction.Meta-analysis of our New Zealand MIF-173G>C data with data from seven additional Caucasian datasets using a random effects model found no association of MIF polymorphisms with CD,UC,or overall IBD.Similarly,meta-analysis of all published MIF-173G>C data from East Asian datasets(416UC patients,789 controls)found no association of this promoter polymorphism with UC.James D Falvey Robert W Bentley Tony R Merriman Mark B Hampton Murray L Barclay Richard B Gearry Rebecca L Roberts 2013World Journal of Gastroenterology2013,19,39:9
2Acute liver failure due to natural killer-like T-cell leukemia/ lymphoma: A case report and review of the Literature显示文摘尖锐的肝失败(ALF ) 是为肝移植要求立即的评估的一种医药紧急情况。我们描述与腹水,黄疸,和脑病介绍了并且被发现由于象 T 房间白血病 / 淋巴瘤一样的生来的杀手(NK ) 有 ALF 的一个病人的一个不平常的盒子。关键免疫显型是 CD2+ , CD3+ , CD7+ , CD56+ 。这诊断,在外部血和腹水基于调查结果,与肝活体检视被证实,并且是到肝移植的禁止徵候。hematologic 恶意是暴发性的肝的失败的一个不平常的原因的文学表演的评论,和那个象 NK 一样 T 房间白血病 / 淋巴瘤是一最近相对表示特性地认出了是的实体 CD3+ 和 CD56+ 。这个盒子证明那肝活体检视在与淋巴瘤 / 白血病能引起尖锐的肝失败的象 NK 一样 T 房间诊断肝的尖锐的肝失败,和那渗入的不平常的原因是必要的。Evan S Dellon Shannon R Morris Wozhan Tang Cherie H Dunphy Mark W Russo 2006World Journal of Gastroenterology2006,12,25:5
3Current state of endohepatology: Diagnosis and treatment of portal hypertension and its complications with endoscopic ultrasound显示文摘The diagnosis and management of cirrhosis and portal hypertension(PH)with its complications including variceal hemorrhage,ascites,and hepatic encephalopathy continues to evolve.Although there are established“standards of care”in liver biopsy and measurement of PH,gastric varices remain an area without a universally accepted therapeutic approach.The concept of“Endo Hepatology”has been used to describe of the applications of endoscopic ultrasound(EUS)to these challenges.EUS-liver biopsy(EUS-LB)offers an alternative to percutaneous and transjuglar liver biopsy without compromising safety or efficacy,and with added advantages including the potential to reduce sampling error by allowing biopsies in both hepatic lobes.Furthermore,EUS-LB can be performed during the same procedure as EUS-guided portal pressure gradient(PPG)measurements,allowing for the collection of valuable diagnostic and prognostic data.EUS-guided PPG measurements provide an appealing alternative to the transjugular approach,with proposed advantages including the ability to directly measure portal vein pressure.In addition,EUS-guided treatment of gastric varices(GV)offers several possible advantages to current therapies.EUS-guided treatment of GV allows detailed assessment of the vascular anatomy,similar efficacy and safety to current therapies,and allows the evaluation of treatment effect through doppler ultrasound visualization.The appropriate selection of patients for these procedures is paramount to ensuring generation of useful clinical data and patient safety.Sean R Rudnick Jason D Conway Mark W Russo 2021World Journal of Hepatology2021,13,8:4
4A multibit E A modulator in floating-body SOS/SOI CMOS for extreme radiation environments显示文摘CHRISTOPHER F E WILLIAM R W MARK B 1999IEEE J of Solid State Circuits1999,34,7:1
5Characterization of a genetic resource collection for Miscanthua ( Saccharinae,Anddropogoneae, Poaceae) using AFLP and ISSR PCR显示文摘TREVOR R HODKINSON MARK W 2002Annals of Botany2002,89,:1
6Poly- morphous low - grade adenocarcinoma and adenoid cystic carcino- ma: a review and comparison of immunohistochemical markers 显示文摘Mark R Darling Johann W Schneider Vincent M Phillips 2002Oral Oncol2002,7,38:1
7NT-proBNP in heart failure therapydecisions and monitoring显示文摘Mark R Richard W 0,,03:1
8Rainfall patterns observed by digitized radar during the landfall of Hurricane Frederic(1979)显示文摘PARRISH J R BURPEE R W MARKS F D 1982Mon Wea Rev1982,110,12:1
9Anisotropic effects on the strain rate dependence of a wrought magnesium alloy 显示文摘MATTHEW T T MARK F H PHILLIP M G HAITHAM E K WILBURN R W 2009Scripta Materialia2009,60,:1
10The effect of allochthonous salt on the petroleum systems of northern Green Canyon and Ewing Bank (offshore Louisiana),northern Gulf of Mexico显示文摘 Paul W Mark G R 1998AAPG Bulletin1998,82,5:1
11Mitochondrial DNA sequence heteroplasmy in the Grand Duke of Russia Georgij Romanov establishes the authenticity of the remains of Tsar Nicholas II显示文摘Pavel L I Mark J W Rhonda K R 1996Nat Genet1996,12,:1
12Tillage effects on soil hydraulic properties in space and time:State of the science显示文摘Mark W S Timothy R G James C A 2008Soil and Tillage Research2008,99,1:1
13Exploiting Data Preparation to Enhance Mining and Knowledge Discovery 显示文摘Balaji R Mark W I 2005IEEE Transactions on Systems Man and Cybernetics Part C Applications and Reviews2005,31,:1
14Histone deacetylase inhibi- tors : molecular mechanisms of action 显示文摘Xu W S Parmigiani R B Marks P A 2007Oncogene2007,26,37:1
15Metabolic response of juvenile gray snapper (Lutjanus griseus ) to temperature and salinity: Physiological cost of different environments 显示文摘MARK J W AMELIA R J JONATHAN A H 2005Journal of Experimental Marine Biology and Ecology2005,321,2:1
16Microbial resistance to metals in the environment 显示文摘BRUINS MARK R SANJAY KAPIL OEHME FREDERICK W 2000Ecotoxicology and Environmental Safety2000,45,:1
17Ray tracing on programmable graphics hardware显示文摘PURCELL T J BUCK I MARK W R 2002ACM Transactions on Graphics2002,21,3:1
18Collective Excitations of Bose-Einstein-condensed Gases at Finite Temperatures显示文摘DODD R J MARK EDWARDS CHARLES W CLARK 1998Phys Rev A1998,57,:1
19Data Storage and Extraction in Engineering Software Using XML显示文摘Mark E W Consolazio G R Hoit M I 2003Advances in Engineering Software2003,36,1112:1
20Distribution of macroinvertebrates in relation to physical and biological variables in the littoral zone of nine New Zealand lakes 显示文摘MARK A W JAMES M R 2001Hydrobiologia2001,462,13:1
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