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| 1 | Upper-gastrointestinal bleeding secondary to peptic ulcer disease:Incidence and outcomes显示文摘AIM:To evaluate the incidence,surgery,mortality,and readmission of upper gastrointestinal bleeding(UGIB)secondary to peptic ulcer disease(PUD).METHODS:Administrative databases identified all hospitalizations for UGIB secondary to PUD in Alberta,Canada from 2004 to 2010(n=7079)using the International Classification of Diseases Codes(ICD-10).A subset of the data was validated using endoscopy reports.Positive predictive value and sensitivity with 95%confidence intervals(CI)were calculated.Incidence of UGIB secondary to PUD was calculated.Logistic regression was used to evaluate surgery,in-hospital mortality,and 30-d readmission to hospital with recurrent UGIB secondary to PUD.Co-variants accounted for in our logistic regression model included:age,sex,area of residence(i.e.,urban vs rural),number of Charlson comorbidities,presence of perforated PUD,undergoing upper endoscopy,year of admission,and interventional radiological attempt at controlling bleeding.A subgroup analysis(n=6356)compared outcomes of patients with gastric ulcers to those with duodenal ulcers.Adjusted estimates are presented as odds ratios(OR)with95%CI.RESULTS:The positive predictive value and sensitivity of ICD-10 coding for UGIB secondary to PUD were85.2%(95%CI:80.2%-90.2%)and 77.1%(95%CI:69.1%-85.2%),respectively.The annual incidence between 2004 and 2010 ranged from 35.4 to 41.2 per100000.Overall risk of surgery,in-hospital mortality,and 30-d readmission to hospital for UGIB secondary to PUD were 4.3%,8.5%,and 4.7%,respectively.Interventional radiology to control bleeding was performed in 0.6%of patients and 76%of these patients avoided surgical intervention.Thirty-day readmission significantly increased from 3.1%in 2004 to 5.2%in 2010(OR=1.07;95%CI:1.01-1.14).Rural residents(OR rural vs urban:2.35;95%CI:1.83-3.01)and older individuals(OR≥65 vs<65:1.57;95%CI:1.21-2.04)were at higher odds of being readmitted to hospital.Patients with duodenal ulcers had higher odds of dying(OR=1.27;95%CI:1.05-1.53),requiring surgery(OR=1.73;95%CI:1.34-2.23),and being readmitted to hospital(OR=1.54;95%CI:1.19-1.99)when compared to gastric ulcers.CONCLUSION:UGIB secondary to PUD,particularly duodenal ulcers,was associated with significant morbidity and mortality.Early readmissions increased over time and occurred more commonly in rural areas. | Samuel Quan Alexandra Frolkis Kaylee Milne Natalie Molodecky Hong Yang Elijah Dixon Chad G Ball Robert P Myers Subrata Ghosh Robert Hilsden Sander Veldhuyzen van Zanten Gilaad G Kaplan | 2014 | World Journal of Gastroenterology2014，20，46： | 21 |
| 2 | 人类血压测量方法:美国心脏协会科学声明显示文摘准确的血压测量对高血压诊断与治疗至关重要。该文是美国心脏协会关于人类血压测量的最新科学声明。业已证实,在诊室许多电子血压计可以准确测量血压,同时减少与听诊法有关的人为误差。即使没有一个观察者在场,全自动电子血压计也可以通过多次测量提供较听诊法更准确的血压测量值。研究表明诊室外所测血压与诊室血压比较存在实质性差别。目前认为动态血压监测是诊室外血压评估的参考标准,当动态血压监测不可行或患者不能耐受时,家庭血压监测则是一个替代方法。 | 赵狄(摘译) 练桂丽(审校) Muntner P Shimbo D Carey RM Charleston JB Gaillard T Misra S Myers MG Ogedegbe G Schwartz JE Townsend RR Urbina EM Viera AJ White WB Wright JT Jr | 2019 | 中华高血压杂志2019，27，6： | 16 |
| 3 | Silicon carbide resonant tuning fork for microsensing applications in high-temperature and high G-shock environments显示文摘We present the fabrication and testing of a silicon carbide(SiC)balanced mass double-ended tuning fork that survives harsh environments without compromising the device strain sensitivity and resolution bandwidth.The device features a material stack that survives corrosive environments and enables high-temperature operation.To perform high-temperature testing,a specialized setup was constructed that allows the tuning fork to be characterized using traditional silicon electronics.The tuning fork has been operated at 600 ℃ in the presence of dry steam for short durations.This tuning fork has also been tested to 64 000 G using a hard-launch,soft-catch shock implemented with a light gas gun.However,the device still has a strain sensitivity of 66 Hz/με and strain resolution of 0.045 με in a 10 kHz bandwidth.As such,this balanced-mass double-ended tuning fork can be used to create a variety of different sensors including strain gauges,accelerometers,gyroscopes,and pressure transducers.Given the adaptable fabrication process flow,this device could be useful to micro-electro-mechanical systems(MEMS) designers creating sensors for a variety of different applications. | David R Myers Kan Bun Cheng Babak Jamshidi Robert G Azevedo Debbie G Senesky Li Chen Mehran Mehregany Muthu B J Wijesundara Albert P Pisano | 2012 | Engineering Sciences2012，10，5： | 6 |
| 4 | NICU随访:0到3岁的医疗和发育管理显示文摘近几十年来,随着早产儿发生率的升高和死亡率的下降,NICU出院患儿的数量持续增加.这些患儿出院后仍需相关服务和指导,以满足他们复杂的医疗、社会、发育和用药的需求.NICU随访需要专业的团队,包括儿科医生、家庭医生及一些亚专科人员共同完成.本文对NICU后续相关常见问题的医疗和发育管理提供指导. | 邱辰 王丹华 Andrews B Pellerite M Myers P | 2015 | 中国新生儿科杂志2015，30，1： | 4 |
| 5 | Environmental exposures and gene regulation in disease etiology 显示文摘 | Edwards T M Myers J P | 2007 | Envi Health Pers2007，115，9： | 1 |
| 6 | A cross-scale model for 3D baroclinic circulation in estuary-plume shelf systems: Ⅰ: For mulation and skill assessment 显示文摘 | ZHANG Y BAPTISTA A M MYERS E P | 2004 | Continental Shelf Research2004，24，： | 1 |
| 7 | Inhibition of retroviral pathogenesis by RNA interference显示文摘 | Hu W Y Myers C P Kilzer J M | 2002 | Curr Biol2002，12，： | 1 |
| 8 | Fish lost at sea:the effect of soak time on pelagic longline catches 显示文摘 | WARD P MYERS R A BLANCHARD W | 2004 | Fishery Bulletin2004，102，1： | 1 |
| 9 | Effects of endothelins on collagen turnover in cardiac fibroblasts 显示文摘 | KATAWA L V MYERS P R | 1993 | Cardiovasc Res1993，27，： | 1 |
| 10 | Anti-inflammatory activity of Chinese medicinal vine plants 显示文摘 | Li R W Lin G D Myers S P | 2003 | J Ethnopharmacol2003，85，： | 1 |
| 11 | Thedirect release of nitric oxide by Gypenoside derived from theHerb Gynostemma pentaphyllum显示文摘 | Miles A Tanner Xin Bu J Alan Steimle P R Myers | 1999 | Biology and Chemis-try1999，3，5： | 1 |
| 12 | Anti-inflammatory activity of Chinese medicinal vine plants显示文摘 | Rachel W Li G David Lin Stephen P Myers David N Leach | 2002 | Journal of Ethnopharmacology2002，，1： | 1 |
| 13 | High noFinal blood pressure and prehypertension:the debate continues显示文摘 | Bolli P Hemmelgran B Myers MG | 2007 | Can J Cardiol2007，23，7： | 1 |
| 14 | An abundance of bidirectional promoters in the human genome显示文摘 | TRINKLEIN N D ALDRED S F HARTMAN S J SCHROEDER D I OTILLAR R P MYERS R M | 2004 | Genome Research2004，14，1： | 1 |
| 15 | Gender differences in attitudes impeding colorectal Cancer screening 显示文摘 | Ritvo P Myers RE Paszat L | 2013 | BMC Public Health2013，13，1： | 1 |
| 16 | Tenofovir DF in antiretroviral-experienced patients : results from a 48-week, randomized, double-blind study 显示文摘 | Schooley RT Ruane P Myers RA | 2002 | AIDS2002，16，9： | 1 |
| 17 | Current transport and the role of barrier inhomogeneities at the high barrier n-InP Ⅰ poly (pyrrole) interface显示文摘 | JONES F E WOOD B P MYERS J A | 1999 | J Appl Phys1999，86，11： | 1 |
| 18 | The antioxidant potential of propofol显示文摘 | Murphy P G Myers D S Davies M J | 1992 | Br J Anaesth1992，68，： | 1 |
| 19 | Effects of Endothelins on Collagen Turnover in Cardiac Fibroblasts显示文摘 | Guarda E Katwa L C Myers P R | 1993 | Cardiovasc Res1993，27，： | 1 |
| 20 | Expression of plasma membrane water channel genes under water stress in Nicotiana excelsior 显示文摘 | Yamada S Komory T Myers P M | 1997 | Plant Cell Physiol1997，38，： | 1 |
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