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| 1 | Role of live microbial feed supplements with reference to anaerobic fungi in ruminant productivity: A review显示文摘To keep the concept of a safe food supply to the consumers, animal feed industries world over are showing an increasing interest in the direct-fed microbials(DFM) for improved animal performance in terms of growth or productivity. This becomes all the more essential in a situation, where a number of the residues of antibiotics and/or other growth stimulants reach in milk and meat with a number of associated potential risks for the consumers. Hence, in the absence of growth stimulants, a positive manipulation of the rumen microbial ecosystem to enhance the feedstuff utilization for improved production efficiency by ruminants has become of much interest to the researchers and entrepreneurs. A few genera of live microbes(i.e., bacteria, fungi and yeasts in different types of formulations from paste to powder) are infrequently used as DFM for the domestic ruminants. These DFM products are live microbial feed supplements containing naturally occurring microbes in the rumen. Among different DFM possibilities, anaerobic rumen fungi(ARF) based additives have been found to improve ruminant productivity consistently during feeding trials. Administration of ARF during the few trials conducted, led to the increased weight gain, milk production, and total tract digestibility of feed components in ruminants. Anaerobic fungi in the rumen display very strong cell-wall degrading cellulolytic and xylanolytic activities through rhizoid development, resulting in the physical disruption of feed structure paving the way for bacterial action. Significant improvements in the fiber digestibility were found to coincide with increases in ARF in the rumen indicating their role. Most of the researches based on DFM have indicated a positive response in nutrient digestion and methane reducing potential during in vivo and/or in vitro supplementation of ARF as DFM. Therefore, DFM especially ARF will gain popularity but it is necessary that all the strains are thoroughly studied for their beneficial properties to have a confirmed ‘generally regarded as safe' status for ruminants. | Anil K Puniya Abdelfattah Z M Salem Sanjay Kumar Sumit S Dagar Gareth W Griffith Monica Puniya Sreenivas R Ravella Nikhil Kumar Tejpal Dhewa Ravinder Kumar | 2015 | Journal of Integrative Agriculture2015，14，3： | 17 |
| 2 | Efficacy of peroral endoscopic myotomy vs other achalasia treatments in improving esophageal function显示文摘AIM: To assess and compare the esophageal function after peroral endoscopic myotomy(POEM) vs other conventional treatments in achalasia.METHODS: Chart review of all achalasia patients who underwent POEM, laparoscopic Heller myotomy(LHM) or pneumatic dilation(PD) at our institution between January 2012 and March 2015 was performed. Patient demographics, type of achalasia, prior treatments, pre- and post-treatment timed barium swallow(TBE) and high-resolution esophageal manometry(HREM) findings were compared between the three treatment groups. Patients who had both pre- and 2 mo posttreatment TBE or HREM were included in the final analysis. TBE parameters compared were barium column height, width and volume of barium remaining at 1 and 5 min. HREM parameters compared were basal lower esophageal sphincter(LES) pressures and LES-integrated relaxation pressures(IRP). Data are presented as mean ± SD, median [25th, 75 th percentiles] or frequency(percent). Analysis of variance, KruskalWallis test, Pearsons χ~2 test and Fishers Exact tests were used for analysis.RESULTS: A total of 200 achalasia patients were included of which 36 underwent POEM, 22 underwent PD and 142 underwent LHM. POEM patients were older(55.4 ± 16.8 years vs 46.5 ± 15.7 years, P = 0.013) and had higher BMI than LHM(29.1 ± 5.9 kg/m^2 vs 26 ± 5.1 kg/m^2, P = 0.012). More number of patients in POEM and PD groups had undergone prior treatments compared to LHM group(72.2% vs 68.2% vs 44.3% respectively, P = 0.003). At 2 mo post-treatment, all TBE parameters including barium column height, width and volume remaining at 1 and 5 min improved significantly in all three treatment groups(P = 0.01 to P < 0.001) except the column height at 1 min in PD group(P = 0.11). At 2 mo post-treatment, there was significant improvement in basal LES pressure and LES-IRP in both LHM(40.5 mm Hg vs 14.5 mm Hg and 24 mm Hg vs 7.1 mm Hg respectively, P < 0.001) and POEM groups(38.7 mm Hg vs 11.4 mm Hg and 23.6 mm Hg vs 6.6 mm Hg respectively, P < 0.001). However, when the efficacy of three treatments were compared to each other in terms of improvement in TBE or HREM parameters at 2 mo, there was no significant difference(P > 0.05).CONCLUSION: POEM, PD and LHM were all effective in improving esophageal function in achalasia at shortterm. There was no difference in efficacy between the three treatments. | Madhusudhan R Sanaka Umar Hayat Prashanthi N Thota Ramprasad Jegadeesan Monica Ray Scott L Gabbard Neha Wadhwa Rocio Lopez Mark E Baker Sudish Murthy Siva Raja | 2016 | World Journal of Gastroenterology2016，22，20： | 7 |
| 3 | The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches显示文摘 | Antonella De Luca Monica R Maiello Amelia D’Alessio Maria Pergameno Nicola Normanno | 2012 | Expert Opinion on Therapeutic Targets2012，，2： | 2 |
| 4 | Leptospirosis: a zoonotic disease of global importance显示文摘 | Ajay R Bharti Jarlath E Nally Jessica N Ricaldi Michael A Matthias Monica M Diaz Michael A Lovett Paul N Levett Robert H Gilman Michael R Willig Eduardo Gotuzzo Joseph M Vinetz | 2003 | The Lancet Infectious Diseases2003，，12： | 2 |
| 5 | Mixed-genome microarrays reveal multiple serotype and LineageSpecific Differences among Strains of Listeria monocytogene 显示文摘 | DOUGLAS R CALL MONICA K BORUCKI THOMAS E BESSER | 2003 | J Clin Microbiol2003，41，2： | 1 |
| 6 | Suspension microarray with deudrimer signal amplification allows direct and high-throuhput subtyping of Listeria monocytogenes from genomic DNA显示文摘 | MONICA K BORUCKI JAMES REYNOLDS DOUGLAS R Call | 2005 | J Clin Microbiol2005，43，7： | 1 |
| 7 | Growth of human melanoma xenografts is suppressed by systemic angiostatin gene therapy显示文摘 | Monica R Enrica M Soldati S | 2001 | Cancer Gene Therapy2001，，8： | 1 |
| 8 | Requirement for IGF-I in Epidermal Growth Factor-Mediated Cell Cycle Progression of Mammary Epithelial Cells显示文摘 | MALINDA A S MONICA M R AIMEE V L | 2002 | Endocrinology2002，143，5： | 1 |
| 9 | AutoantIb0dies to GPI in rheumatoid arthritis;linkage between an animal model and human disease显示文摘 | Monica S Dennis R B Henrik J D | 2001 | Nat Immunol2001，2，1： | 1 |
| 10 | The Insulin-Like Growth Factors (IGFs) and IGF binding proteins in postnatal development of murine mammary glands显示文摘 | TERESA L W MONICA M R MALINDA A S | 2000 | Journal of Mammary Gland Biology and Neoplasia2000，5，1： | 1 |
| 11 | Cardiac troponin T in chest pain unit patients without ischemic electrocardiographic changes: angiographic correlates and long-term clinical outcomes显示文摘 | Christopher R deFilippi Monica Tocchi Rohit J Parmar Salvatore Rosanio Gerard Abreo Marjorie A Potter Marschall S Runge Barry F Uretsky | 2000 | Journal of the American College of Cardiology2000，，7： | 1 |
| 12 | The Insulin-Like Growth Factors (IGF) and IGF type Ⅰ receptor during postnatal growth of the murine mammary gland: sites of messenger ribonucleic acid expression and potential functions显示文摘 | MONICA M R TERESA L W | 1999 | Endocrinology1999，140，1： | 1 |
| 13 | Pyrene degradation by yeasts and filamentous fungi显示文摘 | Cristina R M Monica L S Cecilia C M | 2002 | Environmental Pollution2002，117，： | 1 |
| 14 | Increased genetic diver- sity of BVDV-I: reeent findings and implications thereof显示文摘 | Monica G Letizia C Elisabetta R | 2015 | Virus Genes2015，50，： | 1 |
| 15 | Efficiency and capacity of antioxidant rich foods in trapping peroxyl radicals:A full evaluation of radical scavenging activity显示文摘 | Paola V Monica R Veronica de M | 2011 | Food research International2011，44，1： | 1 |
| 16 | Integrated analysis of gene expression by association rules discovery显示文摘 | PEDRO CS MONICA C ANDRES R | 2006 | BMC Bioinformatics2006，7，： | 1 |
| 17 | Effect of human chorionic gonadctrophin supplementation during different culture periods on in viro maturation of canine oocytes显示文摘 | Monica D R Johanna D L Pedro M | 2005 | Theriogenology2005，64，： | 1 |
| 18 | Autoantibodies to GPI in rheumatoid arthritis:linkage between an animal model and human disease 显示文摘 | Monica S Dennis R B Henrik J D | 2001 | Nat Immunol2001，2，： | 1 |
| 19 | Multiresidue determination of tetracyclines,sulphonamides and chloramphenicol in bovine milk using HPLC-DAD显示文摘 | Monica C V M Felix GRR Sunsanne R | 2009 | Food Chemistry2009，117，3： | 1 |
| 20 | Visual performance result after Tetraftex accommodating intraocular lens implantation 显示文摘 | Donald R Monica L | 2007 | Ophthalmology2007，114，： | 1 |
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