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| 1 | Leptin levels in the differential diagnosis between benign and malignant ascites显示文摘AIM: To evaluate the role of leptin levels in the differential diagnosis of ascites. METHODS: Ascitic leptin, TNFα and serum leptin levels were measured in 77 patients with ascites (35 with malignancies, 30 cirrhosis and 12 tuberculosis). Control serum samples were obtained from 20 healthy subjects. Leptin and TNFα levels were measured by ELISA. Body mass index (BMI) and percentage of body fat (BFM) by skin fold measurement were calculated for all patients and control groups. Peritoneal biopsy, ascites cytology and cultures or biochemical values were used for the diagnosis of patients. RESULTS: In patients with malignancies, the mean serum and ascites leptin levels and their ratios were significantly decreased compared to the other patient groups and controls. In tuberculosis peritonitis, ascitic fluid TNFα levels were significantly higher than malignant ascites and cirrhotic sterile ascites. BMI and BFM values did not distinguish between patients and controls. CONCLUSION: In patients with malignant ascites, levels of leptin and TNFα were significantly lower than in patients with tuberculous ascites. | Mehmet Buyukberber Mehmet Koruk M Cemil Savas Murat T Gulsen Yavuz Pehlivan Rukiye Deveci Alper Sevinc Serdar Gergerlioglu | 2007 | World Journal of Gastroenterology2007，13，3： | 7 |
| 2 | Rhabdomyolysis with different etiologies in childhood显示文摘AIM To investigate different etiologies and management of the rhabdomyolysis in children.METHODS Eight pediatric rhabdomyolysis cases who applied to the Dokuz Eylul University Faculty of Medicine Department of Pediatric Nephrology with different etiologies between January 2004 and January 2012 were evaluated in terms of age, gender, admission symptoms, physical examination findings, factors provoking rhabdomyolysis, number of rhabdomyolysis attacks, laboratory results, family history and the final diagnosis received after the treatment. RESULTS Average diagnosis ages of eight cases were 129(24-192) ± 75.5 mo and five of them were girls. All of them had applied with the complaint of muscle pain, calf pain, and dark color urination. Infection(pneumonia) and excessive physical activity were the most important provocative factors and excessive licorice consumption was observed in one case. In 5 cases, acute kidney injury was determined and two cases needed hemodialysis. As a result of the further examinations; the cases had received diagnoses of rhabdomyolysis associated with mycoplasma pneumoniae, sepsis associated rhabdomyolysis, licorice-induced hypokalemic rhabdomyolysis, carnitine palmitoyltransferase Ⅱ deficiency, very long-chain acyl-CoA dehydrogenase deficiency, congenital muscular dystrophy and idiopathic paroxysmal rhabdomyolysis(Meyer-Betz syndrome).CONCLUSION It is important to distinguish the sporadic and recurrent rhabdomyolysis cases from each other. Recurrent rhabdomyolysis cases should follow up more regardful and attentive. | Demet Alaygut Meral Torun Bayram Belde Kasap Alper Soylu Mehmet Türkmen Salih Kavukcu | 2017 | World Journal of Clinical Pediatrics2017，6，4： | 5 |
| 3 | Therapeutic effect of caffeic acid phenethyl ester on cerulein-induced acute pancreatitis显示文摘AIM: To evaluate the therapeutic role of caffeic acid phenethyl ester (CAPE) in a rat model of ceruleaninduced acute pancreatitis (AP).METHODS: Seventy male Wistar albino rats were divided into seven groups. Acute edematous pancreatitis was induced by subcutaneous cerulein injection (20 μg/kg) four times at 1-h intervals. CAPE (30 mg/kg) was given by subcutaneous injection at the beginning (CAPE 1 group) and 12 h after the last cerulein injection (CAPE 2 group). Serum amylase, lipase, white blood cell count, and tumor necrosis factor (TNF)-α levels were measured, and pancreatic histopathology was assessed. RESULTS: In the AP group, amylase and lipase levels were found to be elevated and the histopathological evaluation showed massive edema and inflammation of the pancreas, with less fatty necrosis when compared with sham and control groups. Amylase and lipase levels and edema formation decreased signif icantly in the CAPE therapy groups (P < 0001); especially in the CAPE 2 group, edema was improved nearly completely (P = 0001). Inflammation and fatty necrosis were partially recovered by CAPE treatment. The pathologicalresults and amylase level in the placebo groups were similar to those in the AP group. White blood cell count and TNF-α concentration was nearly the same in the CAPE and placebo groups.CONCLUSION: CAPE may be useful agent in treatment of AP but more experimental and clinical studies are needed to support our observation of benef icial effects of CAPE before clinical usage of this agent. | Mehmet Buyukberber M Cemil Savas Cahit Bagci Mehmet Koruk Murat T Gulsen Ediz Tutar Tugba Bilgic Nurdan Ceylan | 2009 | World Journal of Gastroenterology2009，15，41： | 4 |
| 4 | Delaying surgery after neoadjuvant chemoradiotherapy improves prognosis of rectal cancer显示文摘AIM To investigate the prognostic effect of a delayed interval between neoadjuvant chemoradiotherapy(CRT) and surgery in locally advanced rectal cancer.METHODS We evaluated 87 patients with locally advanced mid-or distal rectal cancer undergoing total mesorectal excision following an interval period after neoadjuvant CRT at ?i?li Hamidiye Etfal Training and Research Hospital,Istanbul between January 2009 and January 2014.Patients were divided into two groups according to the intervalbefore surgery: < 8 wk(group Ⅰ) and ≥ 8 wk(group Ⅱ).Data related to patients,cancer characteristics and pathological examination were collected and analyzed.RESULTS When the distribution of timing between group Ⅰ(n = 45) and group Ⅱ(n = 42) was viewed,comparison of interval periods(median ± SD) of groups showed a significant difference of as 5 ± 1.28 wk in group Ⅰ and 10.1 ± 2.2 wk in group Ⅱ(P < 0.001).The median follow-up period for all patients was 34.5(9.9-81) mo.group Ⅱ had significantly higher rates of pathological complete response(p CR) than group Ⅰ had(19% vs 8.9%,P = 0.002).Rate of tumor regression grade(TRG) poor response was 44.4% in group Ⅰ and 9.5% in group Ⅱ(P < 0.002).A poor pathological response was associated with worse disease-free survival(P = 0.009).The interval time did not show any association with local recurrence(P = 0.79).CONCLUSION Delaying the neoadjuvant CRT-surgery interval may provide nodal down-staging,improve p CR rate,and decrease the rate of TRG poor response. | Mehmet Mihmanli Esin Kabul Gürbulak Ismail Ethem Akgün Mustafa Fevzi Celayir Pinar Yazici Deniz Tuncel Tuba Tülin Bek Ayhan Oz Sinan Omeroglu | 2016 | World Journal of Gastrointestinal Oncology2016，8，9： | 3 |
| 5 | Frequency tunable microstrip patch antenna using RF MEMS technology显示文摘 | EMRE E KAGAN T MEHMET U | 2007 | IEEE Transactions on Antennas and Propagation2007，55，4： | 1 |
| 6 | Effects of oral fat and glucose tolerance test on serum lipid profde, apolipoprotein, and CRP concentration, and insulin resistance in patients with polycystic ovary syndrome 显示文摘 | Mithat B Mehmet A Alpaslan T | | Fertil Steri0，87，6： | 1 |
| 7 | 3 dB显示文摘 | M Mehmet S Ast T Eberle : Squeezed light at 1550 nm with a quantum noise reduction of 12 | 2011 | Opt Lett2011，19，25： | 1 |
| 8 | Programmed cell death in plants显示文摘 | NARCIN P U ELIF D B MEHMET A T | 2005 | Journal of Cell and Molecular Biology2005，4，： | 1 |
| 9 | Decreased plasma concentrations of adiponectin in patients with slow coronary flow显示文摘 | Hatice S Mehmet Ts Ahmet T | 2009 | Heart Vessels2009，24，1： | 1 |
| 10 | Investigation of knitting architecture on the impact behavior of glass/epoxy composites显示文摘 | Alaattin A Mevlut T Mehmet A | 2013 | Composites: Part B2013，46，： | 1 |
| 11 | Determination of selected polychlorinated biphenyls in soil by miniaturised ultrasonic solvent extraction and gas chromatography-mass-selective detection显示文摘 | MEHMET E A ALI T SENAR O | 2006 | Anal Chim Acta2006，577，2： | 1 |
| 12 | Determination of selected polychlorinated biphenyls in soil by miniaturised ultrasonic solven textraction and gas chromatography mass selective detection显示文摘 | Mehmet E A Ali T Senar O | 2006 | Analytica Chmiica Acta2006，577，： | 1 |
| 13 | Occurrence and biodegradability studies of selected pharmaceuticals and personal care products in sewage effluent显示文摘 | JIM T Y EDWARD J B MEHMET C | 2006 | Agricultural Water Management2006，86，1： | 1 |
| 14 | Pancreatic adenocarcinoma: MDCT versus MRI in the detection and assessment of locoregional extension 显示文摘 | Mehmet Erturk S Ichikawa T Sou H | 2006 | J Cornput Assist Tomogr2006，30，58： | 1 |
| 15 | Heavy Metal Cation Retention by Unconventional Sorbents(Red Muds and Fly Ashes)显示文摘 | Resat Apak Esma Tütem Mehmet Hügül | 1998 | Wat Res1998，32，2： | 1 |
| 16 | Quantification and simulation of particle kinematics and local strains in granular materials using X-ray tomography imaging and discrete-element method 显示文摘 | Fu Yanrong Wang Linbing Tumay Mehmet T | 2008 | Journal of Engineering Mechanics2008，134，2： | 1 |
| 17 | A surface-based method for detection of coronary vessel boundaries in poor quality X-ray angiogram images显示文摘 | Temel K Ali G Mehmet T | 2002 | Pattern Recognition Letters2002，23，： | 1 |
| 18 | Application of Ultrasound-assisted Emulsification-micro-extraction for the Analysis of Organochlorine Pesticides in Waters 显示文摘 | SENAR O ALI T MEHMET E A | 2009 | Water Research2009，43，17： | 1 |
| 19 | Kinetics and mechanism of removal of methylene blue by adsorption onto perlite显示文摘 | MEHMET D MAHIR A AYDM T | 2004 | Journal of Hazardous Materials2004，，109： | 1 |
| 20 | Molecular and physiological changes in maize(Zea mays) induced by exoge- nous NAA, ABA AND MeJa during cold stress显示文摘 | PEYAMI B MEHMET E E MUSA T | 2008 | Annals Botanici Fennici2008，45，： | 1 |
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