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| 1 | Role of quorum sensing in bacterial infections显示文摘Quorum sensing(QS) is cell communication that is widely used by bacterial pathogens to coordinate the expression of several collective traits, including the production of multiple virulence factors, biofilm formation, and swarming motility once a population threshold is reached. Several lines of evidence indicate that QS enhances virulence of bacterial pathogens in animal models as well as in human infections; however, its relative importance for bacterial pathogenesis is still incomplete. In this review, we discuss the present evidence from in vitro and in vivo experiments in animal models, as well as from clinical studies, that link QS systems with human infections. We focus on two major QS bacterial models, the opportunistic Gram negative bacteria Pseudomonas aeruginosa and the Gram positive Staphylococcus aureus, which are also two of the main agents responsible of nosocomial and wound infections. In addition, QS communication systems in other bacterial, eukaryotic pathogens, and even immune and cancer cells are also reviewed, and finally, the new approaches proposed to combat bacterial infections by the attenuation of their QS communication systems and virulence are also discussed. | Israel Castillo-Juárez Toshinari Maeda Edna Ayerim Mandujano-Tinoco María Tomás Berenice Pérez-Eretza Silvia Julieta García-Contreras Thomas K Wood Rodolfo García-Contreras | 2015 | World Journal of Clinical Cases2015，3，7： | 15 |
| 2 | Genetic and phenological variation of tocochromanol(vitamin E)content in wild(Daucus carota L.var.carota)and domesticated carrot(D.carota L.var.sativa)显示文摘Carrot roots(Daucus carota L.var.sativa)produce tocochromanol compounds,collectively known as vitamin E.However,little is known about their types and amounts.Here we determined the range and variation in types and amounts of tocochromanols in a variety of cultivated carrot accessions throughout carrot postharvest storage and reproductive stages and in wild-type roots(Daucus carota L.var.carota).Of eight possible tocochromanol compounds,we detected and quantified α-,and the combined peak for β-and γ-forms of tocopherols and tocotrienols.Significant variation in amounts of tocochromanol compounds was observed across accessions and over time.Large increases in a-tocopherol were noted during both reproductive growth and the postharvest stages.The variation of tocochromanols in carrot root tissue provides useful information for future research seeking to understand the role of these compounds in carrot root tissue or to breed varieties with increased levels of these compounds. | Claire H Luby Hiroshi A Maeda Irwin L Goldman | 2014 | Horticulture Research2014，1，1： | 6 |
| 3 | Rapid detection and identification of two lineages of influenza B strains with monoclonal antibody显示文摘 | Nakagawa N Maeda A Kase T | 1999 | J Virol Methods1999，79，： | 2 |
| 4 | Plasma brain natriuretic peptde level as a biochemical marker of morbidity and mortality in patienst with asymptomatic or minimally symptomatic left ventficular dysfunction 显示文摘 | TASUTAMOTO T WADA A MAEDA K | 1999 | Eur Heart J1999，20，24： | 1 |
| 5 | Plasma brain natriuretic peptide as biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction显示文摘 | Maeda K Tsutamoto T Wada A | 1998 | Am Heart J1998，135，51： | 1 |
| 6 | Open trial of topical tacalcitol and solar irradiation for vitiligo vulgaris: upregulation of c-Kit mRNA by cultured melanocytes 显示文摘 | Ashida M Maeda A | 2003 | Eur J Dermatol2003，13，4： | 1 |
| 7 | Study of the role of the carbohydrate and protein moieties of soy soluble polysaccharides in their emulsifying properties显示文摘 | Nakamura A Yoshida R Maeda H | 2004 | Journal of Agriculture and Food Chemistry2004，52，17： | 1 |
| 8 | Enhanced sensor capability of juxtaposed fi-eyclodextrin rings in TiO2 ultrathin matrix as determined by cyclic surface-polarization impedance measurement 显示文摘 | Yang DH Ju M J Maeda A | 2008 | Sensors and Materials2008，20，4： | 1 |
| 9 | The relationship of preoperative magnetic resonance imaging findings and closed sestem drainage in the recurrence of chronic subdural hematoma显示文摘 | TSUTSUMI K MAEDA K LIJIMA A | 1997 | J Neurosurg1997，87，6： | 1 |
| 10 | Triple Primary Intracranial Tumors of Diffierent Cell Types:a Case Report显示文摘 | Miyagi A Maeda K Sugawara T | 1995 | No Shinkei Geka Neurological Surgery1995，23，6： | 1 |
| 11 | Identification of calponin as a novel substrate of Rho-kinase显示文摘 | Kaneko T Amano M Maeda A | 2000 | Biochem Biophys Res Commun2000，273，： | 1 |
| 12 | Plasma brain natriuretic peptide as a biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction显示文摘 | Maeda K Tsutamoto T Wada A | 1998 | Am Heart J1998，135，5： | 1 |
| 13 | 3D-CT evaluation of facial asymmetry显示文摘 | Katsumata A Fujishita M Maeda M | 2005 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2005，99，2： | 1 |
| 14 | Roles of the Ras-MEK- mitogen-activated protein kinase and phosphatidylinositol 3- kinase Akt-mTOR pathways in jaagsiekte sheep retrovirus- induced transformation of rodent fibroblast and epithelial cell lines 显示文摘 | MAEDA N FU W ORTIN A | 2005 | J Virol2005，79，7： | 1 |
| 15 | Partial laryngospasms during general anesthesia with a laryngeal mask airway for dental treatment:a report of 5 cases显示文摘 | Jinzenji A Maeda S Higuchi H | | 0，，10： | 1 |
| 16 | A met- al-free polymeric photocatalyst for hydrogen produc- tion from water under visible light显示文摘 | WANG X C MAEDA K THOMAS A | 2009 | Nature materi- als2009，，8： | 1 |
| 17 | Induction of osteoblast differentiation indices by statins in MC3T3-E1 cells显示文摘 | Maeda T Matsunuma A Kurahashi I | 2004 | J Cell Bioehem2004，92，3： | 1 |
| 18 | Angiotensin 2 type 1 receptor antagonist decrease plas ma levels of tumor necrosis factor alpha, interleckin 6 and stuble adhesion molecules in patients with chronic heart failure 显示文摘 | Tsutamoto T Wada A Maeda K | 2000 | JAm Coll Cardio2000，35，： | 1 |
| 19 | Improvement of selectivity in 3-ketocellobiose production from cellobiose by Agrobacterium tumefaciens显示文摘 | Adachi S Matsuno R | 2001 | J Biol Chem2001，8，3： | 1 |
| 20 | Isolation of Iron-Oxidizing Bacteria Corroded of Sewage Treatment Plants显示文摘 | Maeda T Negishi A Komodo H | 1999 | Journal of Bioscience and Bioengineering1999，88，3： | 1 |
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