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| 1 | The role of endoscopy in the management of hereditary diffuse gastric cancer syndrome显示文摘Hereditary diffuse gastric cancer(HDGC) syndrome is an inherited cancer risk syndrome associated with path-ogenic germline CDH1 variants. Given the high risk for developing diffuse gastric cancer, CDH1 carriers are recommended to undergo prophylactic total gastrectomy for cancer risk reduction. Current guidelines recommend upper endoscopy in CDH1 carriers prior to surgery and then annually for individuals deferring prophylactic total gastrectomy.Management of individuals from HDGC families without CDH1 pathogenic variants remains less clear, and management of families with CDH1 pathogenic variants in the absence of a family history of gastric cancer is particularly problematic at present. Despite adherence to surveillance protocols, endoscopic detection of cancer foci in HDGC is suboptimal and imperfect for facilitating decision-making. Alternative endoscopic modalities, such as chromoendoscopy,endoscopic ultrasound, and other non-white light methods have been utilized,but are of limited utility to further improve cancer detection and risk stratification in HDGC. Herein, we review what is known and what remains unclear about endoscopic surveillance for HDGC, among individuals with and without germline CDH1 pathogenic variants. Ultimately, the use of endoscopy in the management of HDGC remains a challenging arena, but one in which further research to improve surveillance is crucial. | Shria Kumar Jessica M Long Gregory G Ginsberg Bryson W Katona | 2019 | World Journal of Gastroenterology2019，25，23： | 2 |
| 2 | Successful knowledge management projects显示文摘 | Davenport T T De Long D W Beers M C | 1998 | Sloan Management Review1998，，11： | 2 |
| 3 | The effect of early to mid-gestational nutrient restrietion on female offspring fertility and hypothalamic-pituitary-adrenal axis response to stress 显示文摘 | Long N M Nijland M J Nathanielsz P W | 2010 | J Anim Sci2010，88，6： | 1 |
| 4 | Multiclass linear dimension reduction by weighted Pairwise Fisher criteria显示文摘 | Long M Duin R P W Haeb- Umbach R | 2001 | IEEE Transactions on Pattern Analysis and Machine Intelligence2001，23，7： | 1 |
| 5 | Origin of genes显示文摘 | Gilbert W De Souza S Long M | 1997 | Proc NatlAcad Sci USA1997，94，： | 1 |
| 6 | Isolation and characterization endophytic bacteria from Sedum alfredii Hance and their potential to promote phytoextraction of zinc polluted soil 显示文摘 | LONG X X CHEN X M CHEN Y G WONG J W WEI Z B WU Q T | 2010 | World Journal Microbiology Biotechnology2010，27，： | 1 |
| 7 | Experimental Investigation and Mathematical Modeling of Clearance Brush Seals显示文摘 | TURNER M T CHEW J W LONG C A | | 0，，120： | 1 |
| 8 | Kondo Resonance in a Single-molecule Transistor显示文摘 | LIANG W SHORES M P BOCKRATH M LONG J R PARK H | 2002 | Nature (London)2002，417，： | 1 |
| 9 | Genome shuffling of Megasphaera elsdenii for improving acid-tolerance and propionate production显示文摘 | Long M Li P Zhang W K etal | 2012 | African Journal of Microbi- ology Research2012，6，18： | 1 |
| 10 | Experimental investigation and mathematical modeling of clearance brush seals 显示文摘 | TURNER M T CHEW J W LONG C A | 1998 | Journal of Engineering for Gas Turbines and Power1998，120，： | 1 |
| 11 | The maize epicuticular wax layer provides UV protection显示文摘 | Long L M Patel H P Cory W C | 2002 | Functional Plant Biology2002，30，1： | 1 |
| 12 | Adsorption of 5-Sodiosulfoisophthalic Acids from Aqueous Solution onto Poly(2-vinylpyridine) Resin显示文摘 | Tao W H Li A M Long C | 2010 | Journal of Hazardous materials2010，175，1： | 1 |
| 13 | Efficient photocatalytic degradation of phenol over CO3O4/BiVO4 composite under visible light irradiation 显示文摘 | Long M C Cai W M Cai J | 2006 | J Phys Chem B2006，110，20： | 1 |
| 14 | Optical,structural and thermalcharacteristics of CU-C11AI2O4 hybrids deposited in anodicaluminum oxide as selective solar absorber 显示文摘 | Ding D Cai W Long M | 2010 | Solar EnergyMaterials and Solar Cells2010，94，10： | 1 |
| 15 | Effects of Ga addition on miernstnleture and properties of Sn-Ag-Cu/Cu solder joints显示文摘 | Zhang Q K Long W M | 2015 | Journal of Alloys and Compounds2015，，622： | 1 |
| 16 | Modeling of retention characteristics for metal and semiconductor nanocrystalmemories 显示文摘 | GUAN W H LONG S B LIU M | 2007 | Solid-State Electronics2007，51，5： | 1 |
| 17 | Synthesis of visible-light re- sponsive graphene oxide/TiO2 composites with p/n heterojune- tion显示文摘 | Chen C Cai W M Long M C | 2010 | ACS Nano2010，4，11： | 1 |
| 18 | Thymic epithelial tumours, a population-based study of the incidence, diagnostic procedures and therapy]显示文摘 | de long W K Blaauwgeers 1 L Schaapveld M | 2008 | Eur 1 Cancer2008，44，1： | 1 |
| 19 | Controlled growth of spinel CUAI2O4/Cu hybrid nanorods array by electrodeposition in porousaluminum oxide template显示文摘 | Ding D Cai W Long M | 2012 | Journal of Alloys and Compounds2012，545，： | 1 |
| 20 | The origin of new genes: glimpses from the young and old显示文摘 | Long M Betran E Thornton K Wang W | 2003 | Nature Reviews Genetics2003，4，11： | 1 |
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