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| 1 | Associations of sense of coherence with psychological distress and quality of life in inflammatory bowel disease显示文摘AIM:To investigate the relationship between sense of coherence,psychological distress and health related quality of life in inflammatory bowel disease(IBD).METHODS:This cross-sectional study enrolled a consecutive sample of 147 IBD(aged 45.1 ± 14.1 years; 57.1% female) patients recruited from a tertiary gastroenterology service.Sixty-four participants met diagnostic criteria for Crohn's disease,while eightythree patients had ulcerative colitis.Socio-demographic data(education,age,race,gender,gross monthly income and marital status),disease-related variables(illness activity,relapse rate in past 2 years,history of surgery and time since diagnosis),sense of coherence(Antonovsky's SOC scale),psychological distress symptoms(Hospital Anxiety and Depression Scale) and health-related quality of life(HRQo L; WHOQOLBref) were assessed.Hierarchical multiple regression analyses were performed to identify factors that are independently associated with psychological distress and HRQo L in patients with IBD and to provide indications for possible moderating or mediating effects.In addition,formal moderation and mediation analyses(Sobel tests) were performed to confirm potential moderators/mediators of the relationship between SOC,psychological distress symptoms and HRQoL.RESULTS:Lower SOC scores(std beta=-0.504; P < 0.001),female gender(std beta = 0.176; P = 0.021) and White race(std beta = 0.164; P = 0.033) were independently associated with higher levels of depressive symptoms,while lower levels of SOC(std beta =-0.438; P < 0.001) and higher relapse rate(std beta = 0.161; P = 0.033) were independently associated with more severe anxiety symptoms.A significant interaction between time since diagnosis and SOC was found with regard to the severity of depressive or anxiety symptoms,as the interaction term(time since diagnosis X SOC) had beta coefficients of-0.191(P = 0.009) and-0.172(P = 0.026),respectively.Lower levels of anxiety symptoms(std beta =-0.369; P < 0.001),higher levels of SOC(std beta = 0.231; P = 0.016) and non-White race(std beta =-0.229; P = 0.006),i.e.,mixed-race,which represented the reference category,were independently associated with higher levels of overall HRQoL.Anxiety symptoms were the most potent independent correlate of most aspects of HRQoL.In addition,anxiety mediated the association between SOC and satisfaction with health,as well as its relationship with physical,mental,and social relations HRQo L.Depressive symptoms also mediated the association between SOC and mental HRQoL.CONCLUSION:Our data indicated that SOC is an important construct,as it influences psychological distress and has significant albeit indirect effects on several HRQoL domains in IBD. | Thiago H Freitas Elias Andreoulakis Gilberto S Alves Hesley LL Miranda Lúcia LBC Braga Thomas Hyphantis André F Carvalho | 2015 | World Journal of Gastroenterology2015，21，21： | 10 |
| 2 | Partial sequencing of 5' non-coding region of 7 HGV strains isolated from different areas of China显示文摘 | WANG Xing-Tai ZHUANG Hui SONG Hai-Bo Ll He-Min ZHANG Hua-Yuan and YU Yang(National Institute for the Control of bormceutical and BiologicalPriducts, Beijing 100050, China)(Department of Microbiology, Beijing Medical University, Beijing100083, China)(L | 1999 | World Journal of Gastroenterology1999，5，5： | 7 |
| 3 | Microscopic colitis: A retrospective study of clinical presentation in 53 patients显示文摘AIM: To evaluate the relationship between symptoms and microscopic colitis (MC) subtypes: to test whether collagenous colitis (CC) and/or lymphocytic colitis (LC)might be related to both constipation and diarrhea.METHODS: A cohort of patients with independently confirmed typical histopathological changes was investigated. Fifty-three patients with histologically proved MC (46 with CC, 7 with LC) were included. The existence of diarrhea or constipation and the co-existence of autoimmune diseases were also investigated and all data were retrospectively analyzed.RESULTS: Twenty-three (43.39%) of MC patients had chronic constipation (20 in CC, 3 in LC patients). Twentyfour(45.28%) of MC patients had autoimmune disease and the diagnosis of autoimmune disease was always prior to MC. Sjogren's syndrome was associated only with the constipation subgroup.CONCLUSION: The Janus face of MC resembles the subgroups of irritable bowel syndrome. The co-existence of autoimmune diseases and MC is confirmed in both the constipation and diarrhea subgroups. | Zsolt Barta Gabriella Mekkel István Csíp(o|') László Tóth Szabolcs Szakáll Gábor G.Szabó Gyula Bakó Gyula Szegedi Margit Zeher | 2005 | World Journal of Gastroenterology2005，11，9： | 3 |
| 4 | Effect of inorganic versus organic selenium on hen production and egg selenium eoncentration显示文摘 | Lavergne T K Southern LL | 2005 | Pouh Science2005，84，2： | 1 |
| 5 | Recombinant E1~deleted adenovirus mediated gene therapy for cancer efficacy studies with p53 tumor suppressor gene and liver histology in tumor xenograft models显示文摘 | Nielsen LL Gurnani M Syed L | 1998 | Human gene therapy1998，9，： | 1 |
| 6 | Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus 显示文摘 | Koherman OG Kim DD Shen L Ruggles JA Nielsen LL Fineman MS | 2005 | Am J Health Syst Pharm2005，62，2： | 1 |
| 7 | A Method for Quantifying Vulnerability, Applied to the Agricultural System of the YaquiValley, Mexico 显示文摘 | Amy LL David B L Leonard S S | 2003 | Global Environmental Change2003，13，： | 1 |
| 8 | Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes显示文摘 | P. V. H?jberg T. Vilsb?ll R. Rab?l F. K. Knop M. Bache T. Krarup J. J. Holst S. Madsbad | 2009 | Diabetologia2009，，2： | 1 |
| 9 | Features of airway re- modeling in different types of Chinese chronic rhinosinus- itis are associated with inflammation patterns显示文摘 | Shi LL Xiong P Zhang L | 2013 | Aller- gy2013，68，1： | 1 |
| 10 | Vasomotor symptoms among Japanese-America-n and European-American women living in Hilo,Hawaii显示文摘 | Sievert LL Morrison L Brown DE | 2007 | Menopause2007，14，： | 1 |
| 11 | Distance Between Density Operators:Application to the Jaynes-Cummings Model显示文摘 | KNLL L OROWSKI A | 1995 | Phys Rev A1995，51，2： | 1 |
| 12 | Carrier Densities in InAs/Ga(Al)Sb(As) Quantum Wells显示文摘 | Munekata H Esaki L Chang LL | 1987 | Journal of Vacuum Science and Technology B1987，5，3： | 1 |
| 13 | The human Cyr61 gene is a transcriptional target of transforming growth factor beta in cancer cells显示文摘 | Bartholin L Wessner LL Chirgwin JM | 2007 | Cancer Lett2007，246，2： | 1 |
| 14 | Nitricoxide sythaseactivity in human breast cancer显示文摘 | Thomsen LL Miles DW Happerfield L | 1995 | Br J Cancer1995，72，： | 1 |
| 15 | Pyrrolizidine alkaloid clivofine inhibits human normal liver L-02 cells growth and activates p38 mitogen-activated protein klnase in L-02 cells 显示文摘 | Ji LL Zhao XG Chen L | 2002 | Toxices2002，40，12： | 1 |
| 16 | A genome - wide association study of type 2 diabetes in Finns detects multiple sus- ceptibility variants显示文摘 | Scott L/ Mohlke KL Bonnycastle LL | 2007 | Science2007，316，： | 1 |
| 17 | Anterior cruciate ligament tear: indirect signs at MRimaging显示文摘 | Gentili A Seeger LL Yao L | 1994 | Radiology1994，193，3： | 1 |
| 18 | Acute and chronic animal models for exeessive dermal scarring: quantitative studies 显示文摘 | Morris DE Wu L Zhao LL | 1997 | Plast Reconstr Surg1997，100，3： | 1 |
| 19 | Diagnostic potential of serum proteomic patterns in prostate cancer显示文摘 | Banez LL Prasanna P Sun L | | 0，，： | 1 |
| 20 | An epididymis-specific beta-defensin is important for the initiation of sperm maturation显示文摘 | Zhou CX Zhang YL Xiao L Zheng M Leung KM Chan MY Lo PS Tsang LL Wong HY Ho LS | | 0，，05： | 1 |
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