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| 1 | Retrieval of global terrestrial solar-induced chlorophyll fluorescence from TanSat satellite显示文摘The first Chinese Carbon Dioxide Observation Satellite Mission(TanSat), which was launched on December 21, 2016, is intended to measure atmospheric CO_2 concentration.The high spectral resolution(0.044 nm) and high SNR(360 at 15.2 mW m^(-1) sr^(-1) nm^(-1)) measurements in the region of the O_2-A band of the Atmospheric Carbon dioxide Grating Spectroradiometer(AGCS) module onboard TanSat make it possible to retrieve solar-induced chlorophyll fluorescence(SIF) from TanSat observations at the global scale.This paper aims to explore the potential of the TanSat data for global SIF retrieval.A singular vector decomposition(SVD) statistical method was employed to retrieve SIF using radiance over a micro spectral window(~2 nm) around the Fe Fraunhofer lines(centered at 758.8 nm).The global SIF at 758.8 nm was successfully retrieved with a low residual error of 0.03 mW m^(-1) sr^(-1) nm^(-1).The results show that the spatial and temporal patterns of the retrieved SIF agree well with the global terrestrial vegetation pattern.The monthly SIF products retrieved from the TanSat data were compared with other remote sensing datasets, including OCO-2 SIF, MODIS NDVI, EVI and GPP.The overall consistency between TanSat and OCO-2 SIF products(R^2= 0.86) and the consistency of the spatial patterns and temporal variations between the TanSat SIF and MODIS vegetation indices and GPP enhance our confidence in the potential and feasibility of TanSat data for SIF retrieval.TanSat, therefore, provides a new opportunity for global sampling of SIF at fine spatial resolution(2 km × 2 km), thus improving photosynthesis observations from space. | Shanshan Du Liangyun Liu Xinjie Liu Xiao Zhang Xingying Zhang Yanmeng Bi Lianchong Zhang | 2018 | Science Bulletin2018，63，22： | 29 |
| 2 | Drug resistance mechanisms and novel drug targets for tuberculosis therapy显示文摘Drug-resistant tuberculosis(TB) poses a significant challenge to the successful treatment and control of TB worldwide.Resistance to anti-TB drugs has existed since the beginning of the chemotherapy era.New insights into the resistant mechanisms of anti-TB drugs have been provided.Better understanding of drug resistance mechanisms helps in the development of new tools for the rapid diagnosis of drugresistant TB.There is also a pressing need in the development of new drugs with novel targets to improve the current treatment of TB and to prevent the emergence of drug resistance in Mycobacterium tuberculosis.This review summarizes the anti-TB drug resistance mechanisms,furnishes some possible novel drug targets in the development of new agents for TB therapy and discusses the usefulness using known targets to develop new anti-TB drugs.Whole genome sequencing is currently an advanced technology to uncover drug resistance mechanisms in M.tuberculosis.However,further research is required to unravel the significance of some newly discovered gene mutations in their contribution to drug resistance. | Md Mahmudul Islam H.M. Adnan Hameed Julius Mugweru Chiranjibi Chhotaray Changwei Wang Yaoju Tan Jianxiong Liu Xinjie Li Shouyong Tan Iwao Ojima Wing Wai Yew Eric Nuermberger Gyanu Lamichhane Tianyu Zhang | 2017 | Journal of Genetics and Genomics2017，44，1： | 15 |
| 3 | Folate receptor-mediated boron-10 containing carbon nanoparticles as potential delivery vehicles for boron neutron capture therapy of nonfunctional pituitary adenomas显示文摘Invasive nonfunctional pituitary adenomas(NFPAs) are difficult to completely resect and often develop tumor recurrence after initial surgery.Currently,no medications are clinically effective in the control of NFPA.Although radiation therapy and radiosurgery are useful to prevent tumor regrowth,they are frequently withheld because of severe complications.Boron neutron capture therapy(BNCT) is a binary radiotherapy that selectively and maximally damages tumor cells without harming the surrounding normal tissue.Folate receptor(FR)-targeted boron-10 containing carbon nanoparticles is a novel boron delivery agent that can be selectively taken up by FR-expressing cells via FR-mediated endocytosis.In this study,FR-targeted boron-10 containing carbon nanoparticles were selectively taken up by NFPAs cells expressing FR but not other types of non-FR expressing pituitary adenomas.After incubation with boron-10 containing carbon nanoparticles and following irradiation with thermal neutrons,the cell viability of NFPAs was significantly decreased,while apoptotic cells were simultaneously increased.However,cells administered the same dose of FR-targeted boron-10 containing carbon nanoparticles without neutron irradiation or received the same neutron irradiation alone did not show significant decrease in cell viability or increase in apoptotic cells.The expression of Bcl-2 was down-regulated and the expression of Bax was up-regulated in NFPAs after treatment with FR-mediated BNCT.In conclusion,FR-targeted boron-10 containing carbon nanoparticles may be an ideal delivery system of boron to NFPAs cells for BNCT.Furthermore,our study also provides a novel insight into therapeutic strategies for invasive NFPA refractory to conventional therapy,while exploring these new applications of BNCT for tumors,especially benign tumors. | DAI CongXin CAI Feng HWANG Kuo Chu ZHOU YongMao ZHANG ZiZhu LIU XiaoHai MA SiHai YANG YaKun YAO Yong FENG Ming BAO XinJie LI GuiLin WEI JunJi JIAO YongHui WEI ZhenQing MA WenBin WANG RenZhi | 2013 | Science China(Life Sciences)2013，56，2： | 8 |
| 4 | Cloning and characterization of the gene encoding β-amyrin synthase in the glycyrrhizic acid biosynthetic pathway in Glycyrrhiza uralensis显示文摘Glycyrrhiza uralensis is considered to be one of the most important herbs in traditional Chinese medicine due to its numerous pharmacological effects particularly its ability to relieve cough and act as a mucolytic.Based on previous research,these effects are mediated by a number of active ingredients,especially glycyrrhizic acid(GA).In the present study,a gene encodingβ-amyrin synthase(β-AS)involved in GA biosynthesis in G.uralensis has been cloned and expressed in Saccharomyces cerevisiae.The cloned enzyme showed similar activity to native enzymes isolated from other Glycyrrhiza species to catalyze the conversion of 2,3-oxidosqualene intoβ-amyrin.In fact theβ-AS gene is particularly important in the GA biosynthetic pathway in G.uralensis.The complete sequence of the enzyme was determined and a phylogenetic tree based on theβ-AS gene of G.uralensis and 20 other species was created.This showed that Glycyrrhiza glabra had the closest kinship with G.uralensis.The results of this work will be useful in determining how to improve the efficacy of G.uralensis by improving its GA content and in exploring the biosynthesis of GA in vitro. | Honghao Chen Ying Liu Xiaoqin Zhang Xinjie Zhan Chunsheng Liu | 2013 | Acta Pharmaceutica Sinica B2013，3，6： | 5 |
| 5 | Electropolishing of NiTi for Improving Biocompatibility显示文摘A modified electrolyte (CH_3COOH-HClO_4-A-B) for electropolishing (EP) of NiTi was presented for improving the corrosion resistance and biocompatibility of the alloy.Using the proposed parameters,a homogeneous and uniform surface was obtained.Atomic force microscopy (AFM) revealed that the surface roughness (Ra) for EP sample (23.21 nm) was close to mechanical polishing (MP) sample (19.36 nm).Analysis by X-ray photoelectron spectroscopy (XPS) showed that Ti/Ni ratio increased from 3.1 for MP sample to 27.6 for EP sample.Measurements using potentiodynamic polarization in Hanks' solution showed that no pitting occurred for EP sample even though the applied potential increased up to 1500 mV (vs SCE),while the MP sample was broken down at 650 mV.The present study indicates that electropolishing NiTi with this modified electrolyte contributes to the improved biocompatibility of NiTi. | Wei WU Xinjie LIU Huimin HAN Dazhi YANG Shoudong LU | 2008 | Journal of Materials Science & Technology2008，24，6： | 4 |
| 6 | Homoharringtonine synergy with oridonin in treatment of t(8;21) acute myeloid leukemia显示文摘Collaboration of c-KIT mutations with AML1-ETO (AE) has been demonstrated to induce t(8;21) acute myeloid leukemia (AML).Targeted therapies designed to eliminate AE and c-KIT oncoproteins may facilitate effective treatment of t(8;21) AML.Homoharringtonine (HHT) features activity against tumor cells harboring c-KIT mutations,whereas oridonin can induce t(8;21) AML cell apoptosis and AE cleavage.Therefore,studies should explore the efficacy of combination therapy with oridonin and HHT in t(8;21) AML.In this study,we investigated the synergistic effects and mechanism of oridonin combined with HHT in t(8;21) AML cell line and mouse model.The two drugs synergistically inhibited cell viability and induced significant mitochondrial membrane potential loss and apoptosis.Oridonin and HHT induced significant downregulation of c-KIT and its downstream signaling pathways and promoted AE cleavage.HHT increased intracellular oridonin concentration by modulating the expressions of MRP1 and MDR1,thus enhancing the effects of oridonin.The combination of oridonin and HHT prolonged t(8;21) leukemia mouse survival.In conclusion,oridonin and HHT exert synergistic effects against t(8;21) leukemia in vivo and in vitro,thereby indicating that their combination may be an effective therapy for t(8;21) leukemia. | Weina Zhang Ying Lu Tao Zhen Xinjie Chen Ming Zhang Ping Liu Xiangqin Weng Bing Chen Yueying Wang | 2019 | Frontiers of Medicine2019，13，3： | 4 |
| 7 | Prospects for Solar-Induced Chlorophyll Fluorescence Remote Sensing from the SIFIS Payload Onboard the TECIS-1 Satellite显示文摘The importance of solar-induced chlorophyll fluorescence(SIF)to monitoring vegetation photosynthesis has attracted much attention from the ecological and remote sensing research communities.Space-borne SIF products have been obtained owing to the rapid development of atmospheric satellites in recent years.The SIF Imaging Spectrometer(SIFIS)is a payload onboard the upcoming Terrestrial Ecosystem Carbon Inventory Satellite(TECIS-1)that is specifically designed for SIF monitoring.We conducted an in situ experiment to evaluate the performance of SIFIS on spectral measurement and SIF retrieval through comparison to the commercial spectrometer QE Pro.Disregarding the spatiotemporal mismatch between the collected measurements of the two spectrometers,the radiance spectra obtained synchronously by SIFIS and QE Pro showed a high level of consistency.The SIF retrieval,normalized difference vegetation index(NDVI),and near-infrared radiance of vegetation(NIRvR)results for a push-broom image shows consistent spatial distributions over both vegetated and nonvegetated surfaces.A quantitative comparison was conducted by strictly filtering matching pixels.For the far-red band,a high correlation was obtained between the SIF retrieval performances of SIFIS and QE Pro with R^(2)=0:70 and RMSE=0:30mWm^(−2)sr^(−−1)nm^(−1).However,a relatively poor correlation was observed for the red band with an R^(2)value of 0.23 and an RMSE of 0.26 mWm^(−2)sr^(-−1)nm^(−1).Despite the large uncertainties associated with this experiment,the results indicate that TECIS-1 should offer a reliable SIF monitoring performance after its launch. | Shanshan Du Xinjie Liu Jidai Chen Liangyun Liu | 2022 | Journal of Remote Sensing2022，，1： | 3 |
| 8 | Recent Advances in Closed Loop Spray Cooling and its Application in Airborne Systems显示文摘In recent years,the problem of heat dissipation in airborne directed energy weapons has attracted considerable research interest.Spray cooling can be applied to cool airborne directed energy weapons,owing to its several advantages such as a large heat transfer coefficient,absence of boiling hysteresis and uniform surface temperature.To examine the potential of an airborne spray cooling system,the typical high heat flux dissipation methods were compared,and the state of the art research on spray cooling was reviewed.This review was focused on studies related to the spray cooling hydrodynamic mechanism,experimental studies of closed loop spray cooling,numerical simulation studies about spray cooling and the identification of the factors influencing spray cooling systems,and investigations related to the multiple nozzle spray cooling technology and heat transfer correlation predictions.Overall,there is a need for further research to investigate the failure phenomenon after the critical state,matching operation of the total system and microscopic characteristics of airborne specific parameters. | XU Xinjie WANG Yu JIANG Yanlong LIU Jinxiang YUAN Xiaolei | 2021 | Journal of Thermal Science2021，30，1： | 3 |
| 9 | Derivation and characterization of human embryonic stem cell lines from poor quality embryos显示文摘Poor quality embryos discarded from in vitro fertilization (IVF) laboratories are good sources for deriving human embryonic stem cell (hESC) lines. In this study, 166 poor quality embryos donated from IVF centers on day 3 were cultured in a blastocyst medium for 2 days, and 32 early blastocysts were further cultured in a blastocyst optimum culture medium for additional 2 days so that the inner cell masses (ICMs) could be identified and isolated easily. The ICMs of 17 blastocysts were isolated by a mechanical method, while those of the other 15 blastocysts were isolated by immunosurgery. All isolated ICMs were inoculated onto a feeder layer for subcultivation. The rates of ICM at- tachment, primary ICM colony formation and the efficiency of hESC derivation were similar between the ICMs isolated by the two methods (P>0.05). As a result, four new hESC lines were established. Three cell lines had normal karyotypes and one had an unbalanced Robertsonian translocation. All cell lines showed normal hESC characteristics and had the differentiation ability. In conclusion, we established a stable and effective method for hESC isolation and culture, and it was confirmed that the mechanical isolation was an effective method to isolate ICMs from poor embryos. These results further indicate that hESC lines can be derived from poor quality embryos discarded by IVF laboratories. | Weiqiang Liu, Yifei Yin, Xiaolin Long, Yumei Luo, Yonghua Jiang, Wenhong Zhang, Hongzi Du, Shaoying Li, Yuhong Zheng, Qing Li, Xinjie Chen, Baoping Liao, Guohong Xiao, Weihua Wang, Xiaofang Sun Guangzhou Key Laboratory of Reproductive and Genetics Institute of Gynecology and Obstetrics, The Third Affiliated Hospital of Guangzhou Medical College, Guangzhou 510150, China | 2009 | Journal of Genetics and Genomics2009，36，4： | 3 |
| 10 | Sodium guide star laser generation by single-pass frequency doubling in a periodically poled near-stoichiometric LiTaO_3 crystal显示文摘We report in this work a continuous wave(CW) narrowband 589 nm light generation for the purpose of laser guide assisted adaptive optics.A 39 mm long 1 mm thick periodically poled near stoichiometric LiTaO3 crystal with duty cycle near 50% was fabricated using electrical poling at room temperature and pumped by a Raman fiber amplifier.We tested two temperature control ovens,and a maximum conversion efficiency of about 14.3%,corresponding to 4 W of yellow light with 28 W of fundamental power,and bandwidth less than 0.18 GHz was achieved. | YUAN Ye ZHANG Lei LIU YanHua Lü XinJie ZHAO Gang FENG Yan ZHU ShiNing | 2013 | Science China(Technological Sciences)2013，56，1： | 2 |
| 11 | Heat Transfer Prediction of Supercritical Carbon Dioxide in Vertical Tube Based on Artificial Neural Networks显示文摘Accurate prediction of supercritical CO_(2)(scCO_(2))heat transfer is important for heat exchanger design and safe operation of scCO_(2)power cycles.The main prediction method is empirical correlation.This paper demonstrates an alternative way by artificial neural networks(ANN)model with two hidden layers.To assess widely cited correlations and newly developed ANN model,scCO_(2)heat transfer experiment in vertical tube with pressure up to 20.8 MPa was performed to extend experiment database,which includes 2674 runs.Compared with empirical correlations,the ANN model is promising for following advantages:(1)ANN model has much better prediction accuracy.The mean relative error,mean absolute relative error and the root-mean-square relative error between predicted and measured wall temperatures are eA=0.38%,eR=4.88%and eS=7.29%,respectively.(2)ANN model performs faster computation speed.(3)ANN model can accurately and speedily predict scCO_(2)heat transfer performance for both normal heat transfer and heat transfer deterioration modes.The trained ANN program is provided with this paper,which is a useful tool and can be directly applied in engineering of scCO_(2)heat transfer. | ZHU Bingguo ZHU Xinjie XIE Jian XU Jinliang LIU Huan | 2021 | Journal of Thermal Science2021，30，5： | 2 |
| 12 | Designing heterostructured FeP–CoP for oxygen evolution reaction:Interface engineering to enhance electrocatalytic performance显示文摘It is significant to develop highly efficient electrocatalysts for energy conversion systems.Interface engineering is one of the most feasible approaches to effectively enhance the electrocatalytic activity.Herein,the density functional theory(DFT)calculations predict that the potential barriers of Fe sites at the interface of FeP–CoP heterostructures are lower than that of Fe sites in FeP nanoparticles(NPs),Co sites in CoP NPs,or Co sites in heterostructures.Motivated by the DFT calculation results,FeP–CoP heterostructures have been designed and synthesized by a metal–organic frameworks(MOFs)confined-phosphorization method.The FeP–CoP exhibits the lowest overpotential of 230 mV at the current density of 10 mA·cm^(−2)for oxygen evolution reaction(OER),compared with FeP(470 mV)and CoP(340 mV),which outperforms most of transition metal-based catalysts.The Tafel analysis of FeP–CoP heterostructures shows an improved reaction kinetic pathway with the smallest slope of 90.3 mV·dec^(−1),as compared to the Tafel slopes of FeP NPs(137 mV·dec^(−1))and CoP NPs(114 mV·dec^(−1)).And the FeP–CoP shows extraordinary long-term stability over 24 h.The excellent activity and long-term stability of FeP–CoP derive from the synergistic effect between FeP and CoP. | Shuang Hou Ansai Zhang Qi Zhou Yingjie Wen Sixie Zhang Linfeng Su Xinjie Huang Tian Wang Kun Rui Cheng Wang Huiling Liu Zhiyi Lu Peilei He | 2023 | Nano Research2023，16，5： | 2 |
| 13 | Advances in the development of molecular genetic tools for Mycobacterium tuberculosis显示文摘Mycobacterium tuberculosis, a Gram-positive bacterium of great clinical relevance, is a lethal pathogen owing to its complex physiological characteristics and development of drug resistance. Several molecular genetic tools have been developed in the past few decades to study this microorganism. These tools have been instrumental in understanding how M. tuberculosis became a successful pathogen. Advanced molecular genetic tools have played a significant role in exploring the complex pathways involved in M. tuberculosis pathogenesis. Here, we review various molecular genetic tools used in the study of M. tuberculosis. Further, we discuss the applications of clustered regularly interspaced short palindromic repeat interference(CRISPRi), a novel technology recently applied in M. tuberculosis research to study target gene functions. Finally, prospective outcomes of the applications of molecular techniques in the field of M. tuberculosis genetic research are also discussed. | Chiranjibi Chhotaray Yaoju Tan Julius Mugweru Md Mahmudul Islam H.M.Adnan Hameed Shuai Wang Zhili Lu Changwei Wang Xinjie Li Shouyong Tan Jianxiong Liu Tianyu Zhang | 2018 | Journal of Genetics and Genomics2018，45，6： | 2 |
| 14 | Texture evolution and slip mode of a Ti-5.5Mo-7.2Al-4.5Zr-2.6Sn-2.1Cr dual-phase alloy during cold rolling based on multiscale crystal plasticity finite element model显示文摘The complex micromechanical response among grains remains a persistent challenge to understand the deformation mechanism of titanium alloys during cold rolling.Therefore,in this work,a multiscale crystal plasticity finite element method of dual-phase alloy was proposed and secondarily developed based on LS-DYNA software.Afterward,the texture evolution and slip mode of a Ti-5.5Mo-7.2Al-4.5Zr-2.6Sn-2.1Cr alloy,based on the realistic 3D microstructure,during cold rolling(20%thickness reduction)were systematically investigated.The relative activity of the■slip system in theαphase gradually increased,and then served as the main slip mode at lower Schmid factor(<0.2).In contrast,the contribution of the■slip system to the overall plastic deformation was relatively limited.For theβphase,the relative activity of the<111>{110}slip system showed an upward tendency,indicating the important role of the critical resolved shear stress relationship in the relative activity evolutions.Furthermore,the abnormally high strain of very fewβgrains was found,which was attributed to their severe rotations compelled by the neighboring pre-deformedαgrains.The calculated pole figures,rotation axes,and compelled rotation behavior exhibited good agreement to the experimental results. | Duoduo Wang Qunbo Fan Xingwang Cheng Yu Zhou Ran Shi Yan Qian Le Wang Xinjie Zhu Haichao Gong Kai Chen Jingjiu Yuan Liu Yang | 2022 | Journal of Materials Science & Technology2022，，16： | 2 |
| 15 | Lactobacillus plantarum CCFM8610 Alleviates Irritable Bowel Syndrome and Prevents Gut Microbiota Dysbiosis:A Randomized,Double-Blind,Placebo-Controlled,Pilot Clinical Trial显示文摘Irritable bowel syndrome with diarrhea(IBS-D)is chronic intestinal dysfunction with diarrhea and othercomplicated clinical symptoms,and it has a great impact on the daily life and mental state of patients.Some studies have reported that ingestion of probiotics can significantly alleviate a variety of intestinaldiseases.The pupose of this study was to investigate the IBS-D-alleviating effects of a probiotic strain,lactobacillus plantarum(L.plantarum)CCFM8610,with multiple health-promoting effects.The studywas a 12-week,randomized,double-blind,placebo-controlled,pilot clinical trial.Seventy-five patientswere randomly assigned to receive the placebo,oligosaccharides,or L.plantarum CCFM8610(1×10^(10) colony-forming units(CFU)per day),with a 2-week run-in period,an 8-week intervention period,anda 2-week follow-up observation period.The patients'clinical symptoms and quality of life were exam-ined by the IBS symptom severity scale(IBS-SsS)and the IlBS quality of life scale(IBS-QOL).Changes ingut microbiota composition and diversity were measured at the end of the intervention period.The oraladministration of L.plantarum CCFM8610 significantly decreased the IBS-SSS and IBS-QOL scores,reduced IBS-D symptom severity,recovered gut microbiota diversity,decreased the relative abundanceof bloating-related genus Methanobrevibacter,and increased the relative abundance of butyric acid-producing genera,including Anaerostipes,Anaerotruncus,Bifidobacterium,Butyricimonas,andOdoribacter.These findings suggest that ingestion of L.plantarum CCFM8610 can significantly alleviate clinical symptoms and gut microbiota dysbiosis in IBS-D patients.The IBS-D-alleviating effect of L.plan-tarum CCFM8610 may be related to theincrease in the relative abundance of butyric acid-producing genera in the intestine. | Yang Liu Xinjie Yu Leilei Yu Fengwei Tian Jianxin Zhao Hao Zhang Long Qian Qun Wang Zhengqing Xue Qixiao Zhai Wei Chen | 2021 | Engineering2021，7，3： | 2 |
| 16 | Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology:Implications for Alzheimer's disease therapy显示文摘Alzheimer's disease(AD),characterized by the accumulation of protein aggregates including phosphorylated Tau aggregates,is the most common neurodegenerative disorder with limited therapeutic agents.Autophagy plays a critical role in the degradation of phosphorylated Tau aggregates,and transcription factor EB(TFEB)is a master regulator of autophagy and lysosomal biogenesis.Thus,small-molecule autophagy enhancers targeting TFEB hold promise for AD therapy.Here,we found that celastrol,an active ingredient isolated from the root extracts of Tripterygium wilfordii(Lei Gong Teng in Chinese)enhanced TFEB-mediated autophagy and lysosomal biogenesis in vitro and in mouse brains.Importantly,celastrol reduced phosphorylated Tau aggregates and attenuated memory dysfunction and cognitive deficits in P301S Tau and 3xTg mice,two commonly used AD animal models.Mechanistical studies suggest that TFEB-mediated autophagy-lysosomal pathway is responsible for phosphorylated Tau degradation in response to celastrol.Overall,our findings indicate that Celastrol is a novel TFEB activator that promotes the degradation of phosphorylated Tau aggregates and improves memory in AD animal models.Therefore,Celastrol shows potential as a novel agent for the treatment and/or prevention of AD and other tauopathies. | Chuanbin Yang Chengfu Su Ashok Iyaswamy Senthil Kumar Krishnamoorthi Zhou Zhu Sichang Yang Benjamin Chunkit Tong Jia Liu Sravan G.Sreenivasmurthy Xinjie Guan Yuxuan Kan Aston Jiaxi Wu Alexis Shiying Huang Jieqiong Tan Kingho Cheung Juxian Song Min Li | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 2 |
| 17 | Poaceae Orthologs of Rice OsSGL,DUF1645 Domain-Containing Genes,Positively Regulate Drought Tolerance,Grain Length and Weight in Rice显示文摘Grain yield is a polygenic trait that can be influenced by environmental factors and genetic compositions at all plant growth stages.Currently,the molecular mechanisms behind the coordination of the interaction between grain yield-related traits remain unknown.In this study,we characterized the function of four STRESS_tolerance and GRAIN_LENGTH(Os SGL)Poaceae ortholog genes that are transcribed into DUF1645 domain-containing proteins in relation to the grain length,grain weight,and drought stress-tolerance of rice.The transgenic plants with overexpressing or heterologous high levels of Poaceae OsSGL ortholog genes exhibited longer grain size than the wild type plants.Larger cells were seen in panicles of the four transgenic lines with paraffin sectioning and scanning electron microscopy analyses.In addition,four Poaceae OsSGL ortholog genes positively affected the drought tolerance of rice.Four transgenic plants displayed higher resistance to drought stress at the seedling and vegetative stages.RNA-sequencing and qRT-PCR results indicated that over-or heterologous-expression of four Poaceae OsSGL ortholog genes also affected the transcriptome of rice plants.These genes may play a role in auxin and cytokinin biosynthesis and their transduction pathways.Taken together,these results suggested that the four OsSGL orthologs have a conserved function in the regulation of stress-tolerance and cell growth by modulating hormonal biosynthesis and signaling. | LIU Kai LI Minjuan ZHANG Bin YIN Xuming XIA Xinjie WANG Manling CUI Yanchun | 2022 | Rice science2022，29，3： | 2 |
| 18 | 2 μm optical frequency comb generation via optical parametric oscillation from a lithium niobate optical superlattice box resonator显示文摘Optical parametric oscillators(OPOs) can downconvert the pump laser to longer wavelengths with octave separation via χ^((2)), which is widely used for laser wavelength extension including mid-infrared(MIR) generation.Such a process can be integrated in monolithic resonators, being compact and low in threshold. In this work, we show that the monolithic χ^((2))mini-OPO can also be used for optical frequency comb generation around 2096 nm and enters the boundary of MIR range. A new geometry called an optical superlattice box resonator is developed for this realization with near-material-limited quality factor of 4.0 × 10^(7). Only a continuous-wave near-infrared pump laser is required, with OPO threshold of 80 mW and output power up to 340 mW. Revival temporal profiles are measured at a detectable repetition frequency of 1.426 GHz, and narrow beat note linewidth of less than 10 Hz shows high comb coherence. These results are in good agreement with our simulation for a stable comb generation. Such an OPO-based comb source is useful for carbon dioxide sensing or the mine prospect applications and can be generalized to longer MIR wavelengths for general gas spectroscopy. | Xiaohan Wang Kunpeng Jia Mengwen Chen Shanshan Cheng Xin Ni Jian Guo Yihao Li Huaying Liu Liyun Hao Jian Ning Gang Zhao Xinjie Lv Shu-Wei Huang Zhenda Xie Shi-Ning Zhu | 2022 | Photonics Research2022，10，2： | 1 |
| 19 | Study on the coil design of the reusable linear magnetic flux compressor显示文摘 | Wang Zhanji Li Jun Liu Xinjie | 2003 | IEEE Trans on Magn2003，40，1： | 1 |
| 20 | Recovery and recrystallization in modified 9Cr-1Mo steel weldments after post-weld heat treatment显示文摘 | Qiuzhi Gao Xinjie Di Yongchang Liu Zesheng Yan | 2012 | International Journal of Pressure Vessels and Piping2012，，： | 1 |
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