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| 1 | Conceptualizing and Measuring Economic Resilience of Resource-based Cities: Case Study of Northeast China显示文摘This paper develops a conceptual model and an indicator system for measuring economic resilience of resource-based cities based on the theory of evolutionary resilience and the related concepts of persistence, adaptation, and transformation. Nineteen resource-based cities in Northeast China were analyzed using the indicator system. The results showed that Liaoning and Jilin provinces had higher economic resilience than Heilongjiang Province. Panjin, Benxi, and Anshan in Liaoning Province were the top three cities, while Shuangyashan and other coal-based cities in Heilongjiang Province ranked last. Metals-and petroleum-based cities had significantly higher resilience than coal-based cities. The differences in persistence, adaptability, transformation, and resilience among resource-based cities decreased since the introduction of the Northeast Revitalization Strategy in 2003. Forestry-based cities improved the most in terms of resilience, followed by metals-based and multiple-resource cities; however, resilience dropped for coal-based cities, and petroleum-based cities falling the most. The findings illustrate the importance and the way to develop a differentiated approach to improve resilience among resource-based cities. | TAN Juntao ZHANG Pingyu LO Kevin LI Jing LIU Shiwei | 2017 | Chinese Geographical Science2017，27，3： | 27 |
| 2 | Estimating liver weight of adults by body weight and gender显示文摘瞄准:为了为估计接枝的足够估计标准肝重量,为癌症在主要肝切除术在实时施主肝移植和残余肝缩放。方法:在这研究,体重和身高的人体测量的数据在 159 个实时的肝施主为与肝重量的关联被测试包括中间的肝的静脉经历了施主权利肝切除术。肝重量从在背表格获得的正确脑叶接枝重量被计算,在计算断层摄影术上由正确脑叶的比例划分了。结果:这些题目,所有汉语,有 35.8+/-10.5 年,和女性的吝啬的年龄到 118:41 的男比率。正确脑叶的吝啬的体积是 710.14+/-131.46 mL 并且在计算断层摄影术上占据了整个肝的 64.55%+/-4.47% 。正确脑叶称了 598.90+/-117.39 g,估计的肝重量是 927.54+/-168.78 g。当体重和身高受到多重逐步的线性回归分析时,身高被发现不足道。一样的体重的女性有稍微更低的肝重量。一个公式基于体重和性被导出:估计的标准肝重量(g)= 218 + BW (kg ) x 12.3 + 性 x 51 (R2 = 0.48 )( 女 = 0,男 = 1 ) 。基于这 159 个题目,的人体测量的数据肝重量用在白种人,日语,朝鲜语,和汉语上从研究导出的以前出版的公式被计算。所有公式与这个公式相比过高估计肝重量。日本公式为成年人过高估计估计的标准肝重量(ESLW ) 不到 60 kg。结论:对中国男性和女性适用的一个公式是可得到的。为单个赛跑的一个公式显得必要。 | See Ching Chan Chi Leung Liu Chung Mau Lo Banny K Lam Evelyn W Lee Yik Wong Sheung Tat Fan | 2006 | World Journal of Gastroenterology2006，12，14： | 22 |
| 3 | Analyzing Industrial Structure Evolution of Old Industrial Cities Using Evolutionary Resilience Theory:A Case Study in Shenyang of China显示文摘The recession and revitalization of old industrial cities concerns urban industrial evolution and its characteristics. Based on the theory of evolutionary resilience, we developed an analytical framework for the industrial structure evolution of old industrial cities, and applied the framework to a case study in Shenyang. The following conclusions are drawn. First, since 1978, Shenyang's industrial growth capacity has shown fluctuation between ‘contraction-expansion'. As the secondary industry has a much stronger expansionary and contractionary capacity for growth, this results in lacking stability leading to industrial structure transformation. Second, since 1999, the orientation towards a high-end manufacturing industry in Shenyang has weakened, and the evolution of the new and old growth path is characterized by low-end orientation. Third, since 2007, Shenyang's industrial innovation output capacity has dropped sharply which has been significantly affected by scientific and technological personnel and enterprise-owed science and technology institutions and to a less extent by R&D expenditure. We applied the resilience theory to study the industrial evolution of an old industrial city, explored new study perspectives on industrial evolution and verified the applicability of the resilience theory. This paper provides a scientific reference for understanding the recent deceleration in economic growth in the Northeast old industrial base, and for exploring new paths toward revitalization. | GUAN Haoming LIU Wenxin ZHANG Pingyu LO Kevin LI Jing LI Liangang | 2018 | Chinese Geographical Science2018，28，3： | 12 |
| 4 | Epac2-deficiency leads to more severe retinal swelling, glial reactivity and oxidative stress in transient middle cerebral artery occlusion induced ischemic retinopathy显示文摘Ischemia occurs in diabetic retinopathy with neuronal loss, edema, glial cell reactivity and oxidative stress. Epacs, consisting of Epac1 and Epac2, are c AMP mediators playing important roles in maintenance of endothelial barrier and neuronal functions. To investigate the roles of Epacs in the pathogenesis of ischemic retinopathy, transient middle cerebral artery occlusion(t MCAO) was performed on Epac1-deficient(Epac1-/-) mice, Epac2-deficient(Epac2-/-) mice, and their wild type counterparts(Epac1+/+ and Epac2+/+). Two-hour occlusion and 22-hour reperfusion were conducted to induce ischemia/reperfusion injury to the retina. After t MCAO, the contralateral retinae displayed similar morphology between different genotypes. Neuronal loss, retinal edema and increase in immunoreactivity for aquaporin 4(AQP4), glial fibrillary acidic protein(GFAP), peroxiredoxin 6(Prx6) were observed in ipsilateral retinae. Epac2-/- ipsilateral retinae showed more neuronal loss in retinal ganglion cell layer, increased retinal thickness and stronger immunostaining of AQP4, GFAP, and Prx6 than those of Epac2+/+. However, Epac1-/- ipsilateral retinae displayed similar pathology as those in Epac1+/+ mice. Our observations suggest that Epac2-deficiency led to more severe ischemic retinopathy after retinal ischemia/reperfusion injury. | LIU Jin YEUNG Patrick Ka Kit CHENG Lu LO Amy Cheuk Yin CHUNG Stephen Sum Man CHUNG Sookja Kim | 2015 | Science China(Life Sciences)2015，58，6： | 12 |
| 5 | Alumina-coated Ag nanocrystal monolayers as surfaceenhanced Raman spectroscopy platforms for the direct spectroscopic detection of water splitting reaction intermediates显示文摘 | Xing Yi Ling Ruoxue Yan Sylvia Lo Dat Tien Hoang Chong Liu Melissa A. Fardy Sher Bahadar Khan Abdullah M. Asiri Salem M. Bawaked Peidong Yang | 2014 | Nano Research2014，7，1： | 8 |
| 6 | Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma显示文摘 | Chung-Mau Lo Henry Ngan Wai-Kuen Tso Chi-Leung Liu Chi-Ming Lam Ronnie Tung-Ping Poon Sheung-Tat Fan John Wong | 2002 | Hepatology2002，，5： | 7 |
| 7 | Capsaicin-induced cell death in a human gastric adenocarcinoma cell line显示文摘AIM: Capsaicin, a pungent ingredient found in red pepper,has long been used in spices, food additives, and drugs.Cell death induced by the binding of capsaicin was examined in a human gastric adenocarcinoma cell line (AGS cells).METHODS: By using XTT-based cytotoxicityassay, flow cytometry using the TUNEL method, and quantitation of DNA fragmentation, both cell death and DNA fragmentation were detected in AGS cells treated with capsaicin. By using Western blotting methods, capsaicin reduced the expression of Bcl-2, the antiapoptotic protein, in AGS cells in a concentration-dependent manner.RESULTS: After incubation of AGS cells with capsaicin for 24 h, cell viability decreased significantly in a dose-dependent manner. After incubation of AGS cells with capsaicin for 24 h, apoptotic bodies also significantly increased, and were again correlated with the dose of capsaicin. When the concentration of capsaicin was 1 mmol/L, the amount of DNA fragments also increased. Similar results werealso in the lower traces.CONCLUSION: These results suggest that capsaicininduced cell death might be via a Bcl-2 sensitive apoptotic pathway. Therefore, capsaicin might induce protection from gastric cancer. | Yi-Ching Lo Yuan-Chieh Yang I-Chen Wu Fu-Chen Kuo Chi-Ming Liu Hao-Wei Wang Chao-Hung Kuo Jeng-Yi Wu Deng-Chyang Wu | 2005 | World Journal of Gastroenterology2005，11，40： | 7 |
| 8 | Wide-steering-angle high-resolution optical phased array显示文摘Optical phased array(OPA)technology is considered a promising solution for solid-state beam steering to supersede the traditional mechanical beam steering.As a key component of the LIDAR system for long-range detection,OPAs featuring a wide steering angle and high resolution without beam aliasing are highly desired.However,a wide steering range requires a waveguide pitch less than half of the wavelength,which is easily subjected to cross talk.Besides,high resolution requires a large aperture,and it is normally achieved by a high count number of waveguides,which complicates the control system.To solve the mentioned issues,we design two high-performance 128-channel OPAs fabricated on a multilayered SiN-on-SOI platform.Attributed to the nonuniform antenna pitch,only 128 waveguides are used to achieve a 4 mm wide aperture.Besides,by virtue of innovative dual-level silicon nitride(Si_(3)N_(4))waveguide grating antennas,the fishbone antenna OPA achieves a 100°×19.4°field of view(FOV)with divergence of 0.021°×0.029°,and the chain antenna OPA realizes a 140°×19.23°FOV with divergence of 0.021°×0.1°.To our best knowledge,140°is the widest lateral steering range in two-dimensional OPA,and 0.029°is the smallest longitudinal divergence.Finally,we embed the OPA into a frequency-modulated continuous-wave system to achieve 100 m distance measurement.The reflected signal from 100 m distance is well detected with 26 dBm input transmitter power,which proves that OPA serves as a promising candidate for transceiving optical signal in a LIDAR system. | YINGZHI LI BAISONG CHEN QUANXIN NA QIJIE XIE MIN TAO LANXUAN ZHANG ZIHAO ZHI YUXUAN LI XIAOBIN LIU XIANSHU LUO GUOQIANG LO FENGLI GAO XUEYAN LI JUNFENG SONG | 2021 | Photonics Research2021，9，12： | 7 |
| 9 | Hepatocyte growth factor gene therapy prevents radiation-induced liver damage显示文摘AIM: To transfer human HGF gene into the liver of rats by direct electroporation as a means to prevent radiationinduced liver damage.METHODS: Rat whole liver irradiation model was accomplished by intra-operative approach. HGF plasmid was injected into liver and transferred by electroporation using a pulse generator. Control rats (n = 8) received electrogene therapy (EGT) vehicle plasmid and another 8rats received HGF-EGT 100 μg 48 h before WLIR.Expression of HGF in liver was examined by RT-PCR and ELISA methods. Apoptosis was determined by TUNEL assay. Histopathology was evaluated 10 wk after whole liver irradiation.RESULTS: Marked decrease of apoptotic cells and downregulation of transforming growth factor-beta 1 (TGF-β1)mRNA were observed in the HGF-EGT group 2 d after liver irradiation compared to control animals. Less evidence of radiation-induced liver damage was observed morphologically in liver specimen 10 wk after liver irradiation and longer median survival time was observed from HGF-EGT group (14 wk) compared to control rats (5 wk). (P = 0.031).CONCLUSION: For the first time it has been demonstrated that HGF-EGT would prevent liver from radiation-induced liver damage by preventing apoptosis and down-regulation of TGF-β1. | Chau-Hua Chi I-Li Liu Wei-Yu Lo Bor-Song Liaw Yu-Shan Wang Kwan-Hwa Chi | 2005 | World Journal of Gastroenterology2005，11，10： | 6 |
| 10 | Environmental heavy metals and cardiovascular diseases:Status and future direction显示文摘Cardiovascular disease(CVD)and environmental degradation are leading global health problems of our time.Recent studies have linked exposure to heavy metals to the risks of CVD and diabetes,particularly in populations from low-and middle-income countries,where concomitant rapid development occurs.In this review,we 1)assessed the totality,quantity,and consistency of the available epidemiological studies,linking heavy metal exposures to the risk of CVD(including stroke and coronary heart disease);2)discussed the potential biological mechanisms underlying some tantalizing observations in humans;and 3)identified gaps in our knowledge base that must be investigated in future work.An accumulating body of evidence from both experimental and obser-vational studies implicates exposure to heavy metals,in a dose-response manner,in the increased risk of CVD.The limitations of most existing studies include insufficient statistical power,lack of comprehensive assessment of exposure,and cross-sectional design.Given the widespread exposure to heavy metals,an urgent need has emerged to investigate these putative associations of environmental exposures,either independently or jointly,with incident CVD outcomes prospectively in well-characterized cohorts of diverse populations,and to determine potential strategies to prevent and control the impacts of heavy metal exposure on the cardiometabolic health outcomes of individuals and populations. | Ai-Min Yang Kenneth Lo Tong-Zhang Zheng Jing-Li Yang Ya-Na Bai Ying-Qing Feng Ning Cheng Si-Min Liu | 2020 | Chronic Diseases and Translational Medicine2020，6，4： | 5 |
| 11 | Secondary metabolites of petri-dish cultured Antrodia camphorata and their hepatoprotective activities against alcohol-induced liver injury in mice显示文摘Antrodia camphorata, a well-known and highly valued edible medicinal mushroom with intriguing activities like liver protection, has been traditionally used for the treatment of alcoholic liver disease. A. camphorata shows highly medicinal and commercial values with the demand far exceeds the available supply. Thus, the petri-dish cultured A. camphorata(PDCA) is expected to develope as a substitute. In this paper, nineteen triterpenes were isolated from PDCA, and thirteen of them were the unique anthroic acids in A. camphorata, including the main content antcin K, which suggested that PDCA produced a large array of the same anthroic acids as the wild one. Furthermore, no obvious acute toxicity was found suggesting the edible safety of PDCA. In mice alcohol-induced liver injury model, triglyceride(TG), aspartate aminotransferase(AST), alanine aminotransferase(ALT), and malondialdehyde(MDA) had been reduced by the PDCA powder as well as the main content antcin K, which indicated that the PDCA could protect alcoholic liver injury in mice model and antcin K could be the effective component responsible for the hepatoprotective activities of PDCA against alcoholic liver diseases. | WU Yu TIAN Wen-Jing GAO Shuo LIAO Zu-Jian WANG Guang-Hui LO Jir-Mehng LIN Pei-Hsin ZENG De-Quan QIU Da-Ren LIU Xiang-Zhong ZHOU Mi LIN Ting CHEN Hai-Feng | 2019 | Chinese Journal of Natural Medicines2019，17，1： | 4 |
| 12 | A new insertion sequence for incremental Delaunay triangulation显示文摘Incremental algorithm is one of the most popular procedures for constructing Delaunay triangulations (DTs). However, the point insertion sequence has a great impact on the amount of work needed for the construction of DTs. It affects the time for both point location and structure update, and hence the overall computational time of the triangulation algorithm. In this paper, a simple deterministic insertion sequence is proposed based on the breadth-first-search on a Kd-tree with some minor modifications for better per- formance. Using parent nodes as search-hints, the proposed insertion sequence proves to be faster and more stable than the Hilbert curve order and biased randomized insertion order (BRIO), especially for non-uniform point distributions over a wide range of benchmark examples. | Jian-Fei Liu Jin-Hui Yan S.-H. Lo | 2013 | Acta Mechanica Sinica2013，29，1： | 4 |
| 13 | Quantifying and mapping spatial variability of Shanghai household carbon footprints显示文摘理解家庭碳排出物的空间可变性为提出持续、低碳的精力政策是必要的。然而,家庭碳排出物上的数据在中国被限制,世界最大的温室气体 emitter。这研究确定并且用全市的家庭调查在上海印射家庭碳排出物。调查结果在家庭碳排出物揭示实质的空间可变性,特别在运输相关的排出物。低排放簇在 Hongkou, Xuhui, Luwan, Jinshan,和 Fengxian 被成立。高排放簇位于 Jiading 和 Pudong。总的来说,在上海的家庭碳排出物的空间模式是塑造甜甜圈的:在城市的核心最低,在包围增加郊外的区域,并且在城市的穗和农村区域再衰退。家庭排出物与很多间住房和社会经济的因素被相关,包括汽车所有权,住所的类型,住所的尺寸,住所的年龄,和收入。调查结果下划线低碳的决策和实现的一条局部性的途径的重要性。 | Shangguang YANG Lin LIU Chunlan WANG Kevin LO Mark WANG | 2015 | Frontiers in Energy2015，9，1： | 3 |
| 14 | Toward Current Standards of Donor Right Hepatectomy for Adult-to-Adult Live Donor Liver Transplantation Through the Experience of 200 Cases显示文摘 | See Ching Chan Sheung Tat Fan Chung Mau Lo Chi Leung Liu John Wong | 2007 | Annals of Surgery2007，，1： | 3 |
| 15 | Biliary Complications during Liver Resection显示文摘 | Chi-Ming Lam Chung-Mau Lo Chi-Leung Liu Sheung-Tat Fan | 2001 | World Journal of Surgery2001，，10： | 3 |
| 16 | Continuous Improvement of Survival Outcomes of Resection of Hepatocellular Carcinoma: A 20-Year Experience显示文摘 | Sheung Tat Fan Chung Mau Lo Ronnie T. P. Poon Chun Yeung Chi Leung Liu Wai Key Yuen Chi Ming Lam Kelvin K. C. Ng See Ching Chan | 2011 | Annals of Surgery2011，，4： | 3 |
| 17 | Graft Injury in Relation to Graft Size in Right Lobe Live Donor Liver Transplantation: A Study of Hepatic Sinusoidal Injury in Correlation With Portal Hemodynamics and Intragraft Gene Expression显示文摘 | Kwan Man Sheung-Tat Fan Chung-Mau Lo Chi-Leung Liu Peter Chin-Wan Fung Ting-Bo Liang Terence Kin-Wah Lee Steven Hung-Teng Tsui Irene Oi-Lin Ng Zhi-Wei Zhang John Wong | 2003 | Annals of Surgery2003，，2： | 3 |
| 18 | Experience of donor right lobe hepatectomy in adult-to-adult live donor liver transplantation: clinical analysis of 89 cases显示文摘Objective: To review the experience of donor selec-tion and right lobe hepatectomy in adult-to-adult livedonor liver transplantation.Methods: From May 1996 to December 2001, 89 livedonor liver transplants using right lobe grafts wereperformed at Queen Mary Hospital, Hong Kong. Alldonors had received psychological counseling beforedonor operations. They were screened by laboratorytests including complete blood cell count, liver andrenal biochemistry, and viral serology studies. Com-puted tomography (CT), CT volumetry and hepaticarteriography were routinely performed. All donorsunderwent the operations using the method designedby us.Results: The median duration of the operations was8.8 hours. The median blood loss recorded 466 ml.The median intensive care unit and hospital stayswere 2 and 10 days, respectively. There was no do-nor mortality. Complications of donor operations in-cluded wound infection, urinary tract infection, bili-ary stricture, cholestasis, subphrenic collection,bowel obstruction and incision hernia, etc. All do-nors have recovered and returned to their previousoccupations.Conclusions: Live donation of right lobe grafts for a-dult-to-adult liver transplantation is safe, providedthat donor selection is strict and utmost care is exer-cised during the operation. | Sheung-Tat Fan Chung-Mau Lo Chi-Leung Liu From the Centre for the Study of Liver Disease and Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China | 2002 | Hepatobiliary & Pancreatic Diseases International2002，1，2： | 3 |
| 19 | Dinosaur-bearing strata and K/T boundary in the Luanchuan-Tantou Basin of western Henan Province,China显示文摘The sequence stratigraphy and geochronology of the terrestrial dinosaur-bearing strata,i.e.,the Qiupa Formation,were poorly studied in the Luanchuan-Tantou Basin in western Henan,China.This study shows that these strata represent a complete succession from the Late Cretaceous to the early Paleogene,including the K/T boundary,in this area.Here we report a detailed study of the K/T boundary,especially its stratigraphic sequence,sedimentary characteristics,integrity,continuity,and geological implications. | JIANG XiaoJun LIU YongQing JI ShuAn ZHANG XingLiao XU Li JIA SongHai LO JunChang YUAN ChongXi LI Ming | 2011 | Science China Earth Sciences2011，54，8： | 3 |
| 20 | Hepatectomy for Hepatocellular Carcinoma: Toward Zero Hospital Deaths显示文摘 | Sheung-Tat Fan Chung-Mau Lo Chi-Leung Liu Chi-Ming Lam Wai-Key Yuen Chun Yeung John Wong | 1999 | Annals of Surgery1999，，3： | 3 |
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