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| 1 | Surgical outcomes of mini-open Wiltse approach and conventional open approach in patients with single-segment thoracolumbar fractures without neurologic injury显示文摘This study aimed to introduce a novel mini-open pedicle screw fixation technique via Wiltse approach,and compared it with the traditional posterior open method.A total of 72 cases of single-segment thoracolumbar fractures without neurologic injury underwent pedicle screw fixation via two different approaches.Among them,37 patients were treated using posterior open surgery,and 35 patients received mini-open operation via Wiltse approach.Crew placement accuracy rate,operative time,blood loss,postoperative drainage,postoperative hospitalization time,radiation exposure time,postoperative improvement in R value,Cobb's angle and visual analog scale(VAS)scores of the two methods were compared.There were no significant differences in the accuracy rate of pedicle screw placement,radiation exposure and postoperative R value and Cobb's angle improvement between the two groups.However,the mini-open method had obvious advantages over the conventional open method in operative time,blood loss,postoperative drainage,postoperative hospitalization time,and postoperative improvement in VAS.The mini-open pedicle screw technique could be applied in treatment of single-segment thoracolumbar fracture without neurologic injury and had advantages of less tissue trauma,short operative and rehabilitative time on the premise of guaranteed accuracy rate and no increased radiation exposure. | Haijun Li Lei Yang Hao Xie Lipeng Yu Haifeng Wei Xiaojian Cao | 2015 | The Journal of Biomedical Research2015，29，1： | 43 |
| 2 | Parameters optimum matching of pure electric vehicle dual-mode coupling drive system显示文摘As an important development direction of pure electric vehicle drive system,the distributed drive system has the advantages of compact structure,high transmission efficiency,and flexible control,but there are some serious problems such as high performance requirements to the drive motors,complex control strategies,and poor reliability.To solve these problems,a two motors dual-mode coupling drive system has been developed at first,which not only has the capacity of two-speed gear shifting,but also can automatically switch between the distributed drive and the centralized drive by means of modes change control.So,the performance requirements to the drive motors can be reduced,the problem of abnormal running caused by the fault of unilateral distributed drive systems also can be resolved by replacing the drive mode with centralized drive.Then,the system parameters primary and the optimum matching under the principle of efficiency optimization have been carried out,which makes the drive system achieve predetermined functions and meet the actual demands of different operating statuses.At last,the economic comparison of a pure electric vehicle installation with a dual-mode coupling drive sytem,a single-motor centralized drive system or a dual-motor distributed drive system in the simulation conditions has been completed.Compared with other systems,the driving range of the electric vehicle driven by the designed system is significantly increased,which proves the better efficiency and application value of the system. | ZHANG LiPeng LI Liang QI BingNan WANG Chong ZHANG YaHui SONG Jian | 2014 | Science China(Technological Sciences)2014，57，11： | 22 |
| 3 | Electromechanical coupling driving control for single-shaft parallel hybrid powertrain显示文摘The single-shaft parallel hybrid powertrain with the automatic mechanical transmission(AMT)is an efficient hybrid driving system in the hybrid electric bus(HEB),while the electromechanical coupling driving control becomes a complicated question to find a transient optimal control method to distribute the power between the engine and the electric machine(EM).This paper proposes an innovative control method to deal with the complicated transient coupling driving process of the electromechanical coupling driving system,considering the accelerating condition and the cruising condition mostly in the city driving cycle of HEB.The EM might be operated at driving mode or generating mode to assist the diesel engine to work in its high-efficiency area.Therefore,the adaptive torque tracking controller has been brought forward to ensure that the EM implements the demand torque as well as compensate the torque fluctuation of diesel engine.The d?q axis mathematical model and back stepping method are employed to deduce the adaptive controller and its adaptive laws.Simulation results demonstrate that the proposed control scheme can make the output torque of two power sources respond rapidly to the demand torque from the powertrain in the given driving condition.The proposed method could be adopted in the real control of HEB to improve the efficiency of the hybrid driving system. | YANG Chao JIAO XiaoHong LI Liang ZHANG YaHui ZHANG LiPeng SONG Jian | 2014 | Science China(Technological Sciences)2014，57，3： | 17 |
| 4 | Numerical study of corner separation in a linear compressor cascade using various turbulence models显示文摘Three-dimensional corner separation is a common phenomenon that significantly affects compressor performance.Turbulence model is still a weakness for RANS method on predicting corner separation flow accurately.In the present study,numerical study of corner separation in a linear highly loaded prescribed velocity distribution(PVD) compressor cascade has been investigated using seven frequently used turbulence models.The seven turbulence models include Spalart–Allmaras model,standard k–e model,realizable k–e model,standard k–x model,shear stress transport k–x model,v^2–f model and Reynolds stress model.The results of these turbulence models have been compared and analyzed in detail with available experimental data.It is found the standard k–e model,realizable k–e model,v^2–f model and Reynolds stress model can provide reasonable results for predicting three dimensional corner separation in the compressor cascade.The Spalart–Allmaras model,standard k–x model and shear stress transport k–x model overestimate corner separation region at incidence of 0°.The turbulence characteristics are discussed and turbulence anisotropy is observed to be stronger in the corner separating region. | Liu Yangwei Yan Hao Liu Yingjie Lu Lipeng Li Qiushi | 2016 | Chinese Journal of Aeronautics2016，29，3： | 11 |
| 5 | Plate subduction, oxygen fugacity, and mineralization显示文摘Plate subduction is the largest natural factory that processes elements,which controls recycling and mineralization of a variety of elements.There are three major ore deposit belts in the world:the circumPacific,the centralAsian,and the Tethys belts.All the three belts are closely associated with plate subductions,the mechanism remains obscure.We approached this problem from systematic studies on the behaviours of elements during geologic processes.This contribution summaries the recent progress of our research group.Our results suggest that porphyry Cu deposits form through partial melting of subducted young oceanic crust under oxygen fugacities higher than AFMQ^+1.5,which is promoted after the elevation of atmospheric oxygen at ca.550 Ma.Tin deposits are associated with reducing magmatic rocks formed as a consequence of slab rollback.The Neo-Tethys tectonic regime hosts more than 60%of the world's total Sn reserves.This is due to the reducing environment formed during the subduction of organic rich sediments.For the same reason,porphyry Cu deposits formed in the late stages during the closure of the Neo-Tethys Ocean.Tungsten deposits are also controlled by slab rollback,but is not so sensitive to oxygen fugacity.Subduction related W/Sn deposits are mostly accompanied by abundant accessory fluorites due to the breakdown of phengite and apatite.Decomposition of phengite is also significant for hard rock lithium deposits,whereas orogenic belt resulted from plate subduction promote the formation of Li brine deposits.Cretaceous red bed basins near the Nanling region are favorable for Li brines.Both Mo and Re are enriched in the oxidationreduction cycle during surface processes,and may get further enriched once Mo-,Re-enriched sediments are subducted and involved in magmatism.During plate subduction,Mo and Re fractionate from each other.Molybdenum is mainly hosted in porphyry Mo deposits and to a less extent,porphyry Cu-Mo deposits,whereas Re is predominantly hosted in porphyry Cu-Mo deposits and sedimentary sulfide deposits. | LIU He LIAO Renqiang ZHANG Lipeng LI Congying SUN Weidong | 2020 | Journal of Oceanology and Limnology2020，38，1： | 10 |
| 6 | A study on turbulence transportation and modification of Spalart–Allmaras model for shock-wave/turbulent boundary layer interaction flow显示文摘It is of great significance to improve the accuracy of turbulence models in shock-wave/ boundary layer interaction flow. The relationship between the pressure gradient, as well as the shear layer, and the development of turbulent kinetic energy in impinging shock-wave/turbulent boundary layer interaction flow at Mach 2.25 is analyzed based on the data of direct numerical simulation(DNS). It is found that the turbulent kinetic energy is amplified by strong shear in the separation zone and the adverse pressure gradient near the separation point. The pressure gradient was non-dimensionalised with local density, velocity, and viscosity. Spalart–Allmaras(S–A) model is modified by introducing the non-dimensional pressure gradient into the production term of the eddy viscosity transportation equation. Simulation results show that the production and dissipation of eddy viscosity are strongly enhanced by the modification of S–A model. Compared with DNS and experimental data, the wall pressure and the wall skin friction coefficient as well as the velocity profile of the modified S–A model are obviously improved. Thus it can be concluded that the modification of S–A model with the pressure gradient can improve the predictive accuracy for simulating the shock-wave/turbulent boundary layer interaction. | Ma Li Lu Lipeng Fang Jian Wang Qiuhui | 2014 | Chinese Journal of Aeronautics2014，27，2： | 9 |
| 7 | Large-eddy simulation of shock-wave/turbulent boundary layer interaction with and without Spark Jet control显示文摘The efficiency and mechanism of an active control device ‘‘Spark Jet' and its application in shock-induced separation control are studied using large-eddy simulation in this paper.The base flow is the interaction of an oblique shock-wave generated by 8° wedge and a spatially-developing Ma = 2.3 turbulent boundary layer.The Reynolds number based on the incoming flow property and the boundary layer displacement thickness at the impinging point without shock-wave is20000.The detailed numerical approaches were presented.The inflow turbulence was generated using the digital filter method to avoid artificial temporal or streamwise periodicity.The numerical results including velocity profile,Reynolds stress profile,skin friction,and wall pressure were systematically validated against the available wind tunnel particle image velocimetry(PIV) measurements of the same flow condition.Further study on the control of flow separation due to the strong shock-viscous interaction using an active control actuator ‘‘Spark Jet' was conducted.The single-pulsed characteristic of the device was obtained and compared with the experiment.Both instantaneous and time-averaged flow fields have shown that the jet flow issuing from the actuator cavity enhances the flow mixing inside the boundary layer,making the boundary layer more resistant to flow separation.Skin friction coefficient distribution shows that the separation bubble length is reduced by about 35% with control exerted. | Yang Guang Yao Yufeng Fang Jian Gan Tian Li Qiushi Lu Lipeng | 2016 | Chinese Journal of Aeronautics2016，29，3： | 8 |
| 8 | A new free-hand pedicle screw placement technique with reference to the supraspinal ligament显示文摘We sought to compare the safety and accuracy of a new free-hand pedicle screw placement technique to that of the conventional technique.One hundred fifty-three consecutive adult patients with simple fracture in the thoracic or/and lumbar spine were alternately assigned to either the new free-hand or the conventional group.In the new free-hand technique group,preoperative computerized tomography(CT) images were used to calculate the targeted medial-lateral angle of each pedicle trajectory and the pedicle screw was inserted perpendicular to the corresponding supraspinal ligament.In the conventional technique group,the medial-lateral and cranial-caudal angle of each pedicle trajectory was determined by intraoperatively under fluoroscopic guidance.The accuracy rate of pedicle screw placement,the time of intraoperative fluoroscopy,the operating time and the amount of blood loss during operation were respectively compared.All screws were analyzed by using intraoperative radiographs,intraoperative triggered electromyography(EMG) monitoring data,postoperative CT data and clinical outcomes.The accuracy rate of pedicle screw placement in the new free-hand technique group and the conventional technique group was 96.3% and 94.2%(P < 0.05),respectively.The intraoperative fluoroscopy time of the new technique group was less than that of the conventional technique group(5.37 seconds vs.8.79 seconds,P < 0.05).However,there was no statistical difference in the operating time and the amount of blood loss during operation(P > 0.05).Pedicle screw placement with the free-hand technique which keeps the screw perpendicular to the supraspinal ligament is an accurate,reliable and safe technique to treat simple fracture in the thoracic or lumbar spine. | Juming Li Hong Zhao Hao Xie Lipeng Yu Jifu Wei Min Zong Feng Chen Ziqiang Zhu Ning Zhang Xiaojian Cao | 2014 | The Journal of Biomedical Research2014，28，1： | 7 |
| 9 | Plate convergence in the Indo-Pacific region显示文摘The Indo-Pacific convergence region is the best target to solve the teo remaining challenges of the plate tectonics theory,i.e.,subduction initiation and the driving force of plate tectonics.Recent studies proposed that the Izu-Bonin subduction initiation belongs to spontaneous initiation,which implies that it started from extension,followed by low angle subduction.Numerical geodynamic modeling suggests that the initiation of plate subduction likely occurred along a transform fault,which put the young spreading ridge in direct contact with old oceanic crust.This,however,does not explain the simultaneous subduction initiation in the west Pacific region in the Cenozoic.Namely,the subduction initiations in the Izu-BoninMariana,the Aleutian,and the Tonga-Kermadec trenches are associated with oceanic crusts of different ages,yet they occurred at roughly the same time,suggesting that they were all triggered by a maj or change in the Pacific plate.Moreover,low angle subduction induces compression rather than extension,which requires external compression forces.Given that the famous Hawaiian-Emperor bending occurred roughly at the same time with the onset of westward subductions in the west Pacific,we propose that these Cenozoic subductions were initiated by the steering of the Pacific plate,which are classified as induced initiation.Induced subduction initiation usually occurs in young ocean basins,forming single-track subduction.The closure s of Neo-Tethys Oceans were likely triggered by plume s in the south,forming northward subductions.Interestingly,the Indian plate kept on moving northward more than 50 Ma after the collision between the Indian and Eurasian continents and the break-off of the subducted oceanic slab attached to it.This strongly suggests that slab pull is not the main driving force of plate tectonics,whereas slab sliding is. | SUN Weidong ZHANG Lipeng LIAO Renqiang SUN Saijun LI Congying LIU He | 2020 | Journal of Oceanology and Limnology2020，38，4： | 4 |
| 10 | Numerical analysis of dynamic response of vehicle–bridge coupled system on long-span continuous girder bridge显示文摘To systematically study the vehicle–bridge coupled dynamic response and its change rule with different parameters, a vehicle model with seven degrees of freedom was built and the total potential energy of vehicle space vibration system was deduced. Considering the stimulation of road roughness, the dynamic response equation of vehicle–bridge coupled system was established in accordance with the elastic system principle of total potential energy with stationary value and the ‘‘set-in-right-position'' rule. On the basis of the self-compiled Fortran program and bridge engineering, the dynamic response of longspan continuous girder bridge under vehicle load was studied. This study also included the calculation of vehicle impact coefficient, evaluation of vibration comfort, and analysis of dynamic response parameters.Results show the impact coefficient changes with lane number and is larger than the value calculated by the ‘‘general code for design of highway bridges and culverts(China)''. The Dieckmann index of bridge vibration is also related to lane number, and the vibration comfort evaluation is good in normal conditions.The relevant conclusions from parametric analyses have practical significance to dynamic design and daily operation of long-span continuous girder bridges in expressways. Safety and comfort are expected to improve significantly with further control of the vibration of vehicle–bridge system. | Lipeng An Dejian Li Peng Yu Peng Yuan | 2016 | Theoretical & Applied Mechanics Letters2016，6，4： | 4 |
| 11 | Evaluation of Surface Relative Humidity in China from the CRA-40 and Current Reanalyses显示文摘Recently,the China Meteorological Administration(CMA)released a new Global Atmospheric Reanalysis(CRA-40)dataset for the period 1979−2018.In this study,surface relative humidity(RH)from CRA-40 and other current reanalyses(e.g.,CFSR,ERA5,ERA-Interim,JRA-55,and MERRA-2)is comprehensively evaluated against homogenized observations over China.The results suggest that most reanalyses overestimate the observations by 15%−30%(absolute difference)over the Tibetan Plateau but underestimate the observations by 5%−10%over most of northern China.The CRA-40 performs relatively well in describing the long-term change and variance seen in the observed surface RH over China.Most of the reanalyses reproduce the observed surface RH climatology and interannual variations well,while few reanalyses can capture the observed long-term RH trends over China.Among these reanalyses,the CFSR does poorly in describing the interannual changes in the observed RH,especially in Southwest China.An empirical orthogonal function(EOF)analysis also suggests that the CRA-40 performs better than other reanalyses to capture the first two leading EOF modes revealed by the observations.The results of this study are expected to improve understanding of the strengths and weaknesses of the current reanalysis products and thus facilitate their application. | Jingpeng ZHANG Tianbao ZHAO Zhi LI Chunxiang LI Zhen LI Kairan YING Chunxiang SHI Lipeng JIANG Wenyu ZHANG | 2021 | Advances in Atmospheric Sciences2021，38，11： | 4 |
| 12 | Rollover prevention control for a four in-wheel motors drive electric vehicle on an uneven road显示文摘When a four in-wheel motors drive electric vehicle with a specific wheels mass is running on an uneven road and transient steering occurs in the meantime, the joint action of the large unsprung dynamic load and the centrifugal force may cause the vehicle to rollover. To avoid the above accident, a rollover prevention control method based on active distribution of the in-wheel motors driving torques is investigated. First, the rollover evolution process of the four in-wheel motors drive electric vehicle under the described operating condition is analyzed. Next, a multiple degrees of freedom vehicle dynamics model including an uneven road tyre model is established, and the rollover warning threshold is determined according to the load transfer ratio. Then, the hypothesis of the effects of unsprung mass on the vehicle roll stability on a plat road and on an uneven road is verified respectively. Finally, a rollover prevention controller is designed based on the distribution of the four wheels driving torques with sliding mode control,and the control effect is verified by simulations. The conclusion shows that, once the wheels mass does not match road conditions,the large unsprung mass may play a detrimental role on the vehicle roll stability on an uneven road, which is different from the beneficial role of large unsprung mass on the vehicle roll stability on a plat road. With the aforementioned rollover prevention controller, the vehicle rollover, which is caused by the coupling effect between large unsprung dynamic load and suspension potential energy on an uneven road, can be avoided effectively. | ZHANG LiPeng LI Liang QI BingNan | 2018 | Science China(Technological Sciences)2018，61，6： | 4 |
| 13 | A panel of monoclonal antibodies against the prion protein proves that there is no prion protein in human pancreatic ductal epithelial cells显示文摘Prion diseases are a group of neurodegenerative diseases that are fatal. The study of these unique diseases in China is hampered by a lack of resources. Amongst the most important resources for biological study are monoclonal antibodies. Here, we characterize a panel of monoclonal antibodies specific for cellular prion protein by enzyme-linked immunosorbent assay(ELISA), immunofluorescent staining, flow cytometry, and western blotting. We identify several antibodies that can be used for specific applications and we demonstrate that there is no prion protein expression in human pancreatic ductal epithelial cells(HPDC). | Liheng Yang Yan Zhang Lipeng Hu Ying Zhu Man-Sun Sy Chaoyang Li | 2014 | Virologica Sinica2014，29，4： | 3 |
| 14 | Composition demixing effect on cathodic arc ion plating显示文摘The composition demixing effect has been found often in alloy coatings deposited by cathodic arc ion plating using variousalloy cathode targets. The characteristics of composition demixing phenomena were summarized. Beginning with the ionization zonenear the surface of the cathode target, a physical model in terms of the ions generated in the ionization zone and their movement in theplating room modified by bias electric field was proposed. Based on the concept of electric charge state, the simulation calculation ofthe composition demixing effect was carried out. The percentage of atoms of an element in coating and from the alloy target was de-monstrated by direct comparison. The influences of the composition change of the alloy target and the bias electric field on the compo-sition demixing effect were discussed in detail. It is also proposed that the average charge states of the elements may be used to calcu-late the composition demixing effect and to design the composition of the alloy target. | Jun Zhang Li Li Lipeng Zhang Shilu Zhao Qiang Guo | 2006 | Journal of University of Science and Technology Beijing2006，13，2： | 3 |
| 15 | Comprehensive test stand for high-intensity cyclotron development显示文摘A comprehensive test stand for high-intensity cyclotron development,a 10 MeV 430 μA cyclotron,has been successfully constructed at China Institute of Atomic Energy (CIAE) for the experimental verification of the viability of a 100 MeV high-intensity cyclotron (CYCIAE-100) being constructed at CIAE.The verification includes the overall design technology,detail design and engineering technology for the crucial parts of the machine,e.g.main magnet and beam diagnostics.It will also pave the way for future enhancement of the beam intensity.The test stand consists of a H-ion source,axial injection system,central region,main magnet and coil,RF resonator,stripping extraction,and auxiliary systems,which include the RF power amplifier,high voltage and DC power supplies,electric apparatus,beam diagnostics,control,vacuum,water cooling,pneumatic system,and safety interlock.This paper presents the work regarding the design and sub-system development of the test sand,and the results of the beam commissioning of the machine. | ZHANG TianJue LI ZhenGuo CHU ChengJie XING JianSheng GUAN FengPing ZHONG JunQing JI Bin GE Tao YIN ZhiGuo HOU ShiGang PAN GaoFeng YAO HongJuan LU YinLong WANG ZhenHui WU LongCheng LIN Jun JIA XianLu WEI SuMin WEN LiPeng WANG Feng XIA Le CAI HongRu XIE HuaiDong CHEN RongFan ZHANG Yan ZHANG SuPing LIU GengShou ZOU Jian AN ShiZhong YANG JianJun BI YuanJie YANG Fang | 2011 | Chinese Science Bulletin2011，56，3： | 3 |
| 16 | Neuroprotective effect of early and short-time applying sophoridine in pMCAO rat brain: Down-regulated TRAF6 and up-regulated p-ERK1/2 expression, ameliorated brain infaction and edema显示文摘 | Zongjie Liu Dan He Xiangjian Zhang Yanhua Li Chunhua Zhu Lipeng Dong Xiaolin Zhang Yinxue Xing Chaohui Wang Huimin Qiao Linyu Chen | 2012 | Brain Research Bulletin2012，，4： | 2 |
| 17 | Role ofβ(FeA1)nanoparticles in abnormal grain growth in the annealing of cast Cu-Al-Mn-Fe shape memory alloys显示文摘In this study,the low-cost production of Cu-AI-Mn-Fe shape memory alloy single crystals exceeding 46 mm by abnormal grain growth was realized only through annealing their cast alloys.The results show that the mis-orientation formed during annealing may be responsible for such abnormal grain growth process.It was con-firmed that this misorientation resulted from the dissolution of bec B(FeAI)nanoparticles during heat treatment at a sufficiently temperature of approximately 1173 K.The rate of migration of the abnormal grain boundary was experimentally measured to be approximately9.3 x 10^-m s^-1within 2 min of the commencement of abnormal grain growth.Additionally,the range of composition of the alloys that can lead to abnormal grain growth was determined.When the Cu-13.0AI-6.5Mn-3.2Fe single crystal close to the[100]direction was deformed to a pre-strain of 12%,full shape recovery happened without any residual strain.At that time,the superelastic strain was approximately 9%.Such a superelastic characteristic remained nearly constant over 50 cycles,showing excellent fatigue resistance.The superelastic properties of the present Cu-13.0AI-6.5Mn-3.2Fe single crystal are compared to those of commercial Ni-Ti-based shape memory alloys.Therefore,it can be considered as a new kind of superelastic material having practical applications.The obtained results should be of great significance in the development of Cu based shape memory alloys.Furthermore,it is expected that a similar microstructure can be designed for the production of more metallic single crystals. | Shuiyuan Yang Xinyu Qing Jixun Zhang Lipeng Guo Shen Hong Mingpei Li Jinbin Zhang Cuiping Wang Xingjun Liu | 2020 | Progress in Natural Science:Materials International2020，30，4： | 2 |
| 18 | Redox-responsive biocompatible nanocarriers based on novel heparosan polysaccharides for intracellular anticancer drug delivery显示文摘Heparosan is a natural precursor of heparin biosynthesis in mammals. It is stable in blood circulation but can be degraded in lysosomes, showing good biocompatibility and long circulation features. So heparosan can be designed as anticancer drug carriers to increase tumor selectivity and improve the therapeutic effect. A novel redox-sensitive heparosancystamine-vitamin E succinate(KSV) micelle system was constructed for intracellular delivery of doxorubicin(DOX). Simultaneously, the redox-insensitive heparosan-adipic acid dihydrazide-vitamin E succinate copolymer(KV) was synthesized as control. DOX-loaded micelles(DOX/KSV) with an average particle size of 90–120 nm had good serum stability and redox-triggered depolymerization. In vitro drug release test showed that DOX/KSV micelles presented obvious redox-triggered release behavior compared with DOX/KV. Cytotoxicity and cell uptake were investigated using MGC80-3 tumor cells and COS7 fibroblast-like cells. The cell survival rate of blank micelles was more than 90%, and the cytotoxicity of DOX/KSV in MGC80-3 cells was higher than in COS7 cells, indicating that the carrier has better biocompatibility and less toxicity side effect. The cytotoxicity of DOX/KSV against MGC80-3 cells was significantly greater than that of free DOX and DOX/KV. Furthermore, compared with DOX/KV in MGC80-3 cells, DOX/KSV micelles uptook more anticancer drugs and then released DOX faster into the cell nucleus. The micelles were endocytosed by multiple pathways, but clathrin-mediated endocytosis was the main pathway. Therefore, heparosan polysaccharide could be a potential option as anticancer carrier for enhancing efficacy and mitigating toxicity. | Lipeng Qiu Lu Ge Miaomiao Long Jing Mao Kamel SAhmed Xiaotian Shan Huijie Zhang Li Qin Guozhong Lv Jinghua Chen | 2020 | Asian Journal of Pharmaceutical Sciences2020，15，1： | 2 |
| 19 | Action mechanisms and research methods of tRNA-derived small RNAs显示文摘tRNA-derived small RNAs(tsRNAs),including tRNA-derived fragments(tRFs)and tRNA halves(tiRNAs),are small regulatory RNAs processed from mature tRNAs or precursor tRNAs.tRFs and tiRNAs play biological roles through a variety of mechanisms by interacting with proteins or mRNA,inhibiting translation,and regulating gene expression,the cell cycle,and chromatin and epigenetic modifications.The establishment and application of research technologies are important in understanding the biological roles of tRFs and tiRNAs.To study the molecular mechanisms of tRFs and tiRNAs,researchers have used a variety of bioinformatics and molecular biology methods,such as microarray analysis,real-time quantitative reverse transcription-polymerase chain reaction(qRT-PCR);Northern blotting;RNA sequencing(RNA-seq);cross-linking,ligation and sequencing of hybrids(CLASH);and photoactivatable-ribonucleoside-enhanced cross-linking and immunoprecipitation(PAR-CLIP).This paper summarizes the classification,action mechanisms,and roles of tRFs and tiRNAs in human diseases and the related signal transduction pathways,targeted therapies,databases,and research methods associated with them. | Yaoyao Xie Lipeng Yao Xiuchong Yu Yao Ruan Zhe Li Junming Guo | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 2 |
| 20 | Advances and perspectives in catalytic oxidation of hydrocarbons in liquid phase显示文摘This review article summarizes recent advances in catalytic oxidation of hydrocarbons,especially presents two strategies for activation of C-H bonds or molecular oxygen.Based on our own research results,the applications of the two methods in the oxidation of cyclohexane,toluene and ethyl benzene,etc.are introduced,and the perspectives of the two methods are also discussed. | Zhou Lipeng Yang Guanyu Zhang Wei Sun Zhiqiang Gao Jin Miao Hong Chen Chen Ma Hong Li Xiaoqiang Zhang Qiaohong Wang Feng Tong Xinli Xu Jie | 2007 | Progress in Natural Science:Materials International2007，17，9： | 2 |
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