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| 1 | Subcycle control of terahertz waveform polarization using all-optically induced transient metamaterials显示文摘Coherent radiation with frequencies ranging from 0.3 to 30 THz has recently become accessible using femtosecond laser technology.These terahertz(THz)waves have already been applied in spectroscopy and imaging and can be manipulated using static optical elements such as lenses,polarizers and filters.However,ultrafast modulation of THz radiation is required as well,for instance,in short-range wireless communication or for preparing shaped THz transients for the coherent control of numerous material excitations.Here,we demonstrate an all-optically created transient metamaterial that allows us to manipulate the polarization of THz waveforms with subcycle switch-on times.The polarization-modulated pulses are potentially interesting for controlling elementary motions such as the vibration of crystal lattices,the rotation of molecules and the precession of spins. | N Kamaraju Andrea Rubano Linke Jian Surajit Saha T Venkatesan Jan Notzold R Kramer Campen Martin Wolf Tobias Kampfrath | 2014 | Light(Science & Applications)2014，3，1： | 5 |
| 2 | Strong prognostic value of nodal and bone marrow micro-involvement in patients with pancreatic ductal carcinoma receiving no adjuvant chemotherapy显示文摘AIM: To study the prognostic value of adjuvant chemo-therapy in patients with pancreatic, ductal adenocar-cinoma.METHODS: Lymph nodes from 106 patients with resectable pancreatic ductal adenocarcinoma were systematically sampled. A total of 318 lymph nodes classified histopathologically as tumor-free were examined using sensitive immunohistochemical assays. Forty-three (41%) of the 106 patients were staged as pT1/2, 63 (59%) as pT3/4, 51 (48%) as pN0, and 55 (52%) as pN1. The study population included 59 (56%) patients exhibiting G1/2, and 47 (44%) patients with G3 tumors. Patients received no adjuvant chemo- or radiation therapy and were followed up for a median of 12 (range: 3.5 to 139) mo.RESULTS: Immunostaining with Ber-EP4 revealed nodal microinvolvement in lymph nodes classified as “tumor free” by conventional histopathology in 73 (69%) out of the 106 patients. Twenty-nine (57%)of 51 patients staged histopathologically as pN0 had nodal microinvolvement. The five-year survival probability for pN0-patients was 54% for those without nodal microinvolvement and 0% for those with nodal microinvolvement. Cox-regression modeling revealed the independent prognostic effect of nodal microinvolvement on recurrence-free (relative risk 2.92, P = 0.005) and overall (relative risk 2.49, P = 0.009) survival.CONCLUSION: The study reveals strong and independent prognostic significance of nodal microinvolvement in patients with pancreatic ductal adenocarcinoma who have received no adjuvant therapy. The addition of immunohistochemical findings to histopathology reports may help to improve risk stratification of patients with pancreatic cancer. | Emre F Yekebas Dean Bogoevski Michael Bubenheim Bjrn-Christian Link Jussuf T Kaifi Robin Wachowiak Oliver Mann Asad Kutup Guellue Cataldegirmen Lars Wolfram Andreas Erbersdobler Christoph Klein Klaus Pantel Jakob R Izbicki | 2006 | World Journal of Gastroenterology2006，12，40： | 3 |
| 3 | Antibody-positive paraneoplastic neurologic syndromes: value of CT and PET for tu- mor diagnosis显示文摘 | Linke R Schroeder M Helmberger T | 2004 | Neurology2004，63，2： | 1 |
| 4 | Antibody-positive paraneo- plastie neurologie syndromes :value of CT and PET for tumor diagnosis 显示文摘 | Linke R Schroeder M Helmberger T | 2004 | Neurology2004，63，2： | 1 |
| 5 | Cartilage imaging: motivation, techniques, current and future significance显示文摘 | Link T M Stah| R Woertler K | 2007 | Eur Radiol2007，17，5： | 1 |
| 6 | The influence of nitrogen and potassiumfertilization on the yield,quality and chemical composition ofburley tobacco显示文摘 | Link K A Terrill T R | 1982 | Tobacco Science1982，26，： | 1 |
| 7 | Progress towards glucagon receptor antagonist therapy for type 2 diabetes 显示文摘 | KURUKULASURIYA R LINK J T | 2005 | Expert Opin Ther Pat2005，15，12： | 1 |
| 8 | Dynamic MR pancreatography after secretin administration: image quality and diagnostic accuracy 显示文摘 | Hellerhoff K J Helmberger H Rosch T Settles M R Link T M Rummeny E J | 2002 | Am J Radiol2002，179，： | 1 |
| 9 | The clinical relevance of assessing advanced glycation endproducts accumulation in diabetes显示文摘 | MEERWALDT R LINKS T ZEEBREGTS C | 2008 | Cardiovasc Diabetol2008，77，： | 1 |
| 10 | Dry beneficiationof slovakian coal 显示文摘 | Soong Y Link T A Schofftall M R | | Fuel Processing Technology0，72，3： | 1 |
| 11 | Biomolecular screening with encoded porous-silicon photonic crystals显示文摘 | Cunin F Schmedake T A Link J R | 2002 | Na- ture Materials2002，1，1： | 1 |
| 12 | Pedicle screw instrumentation of the thoracic spine in idiopathic scoliosis显示文摘 | Liljenqvist U R Halm H F H Link T M | 1997 | Spine1997，22，19： | 1 |
| 13 | The clinical relevance of as-sessingadvanced glycation endproducts accumulation in diabetes显示文摘 | Meerwaldt R Links T Zeebregts C | | 0，，： | 1 |
| 14 | Six minute walking distance in helthy elderly subjects显示文摘 | Troosters T Gosse link R Decramer M | 1999 | Eur Respir J1999，14，2： | 1 |
| 15 | Morphometrie analysis of thoracic and lumbar vertebrae in idiopathic seoliosis显示文摘 | Liljenqvist U R Link T M Halm H F | 2000 | Spine2000，25，65： | 1 |
| 16 | Enhanced nonlinear optical conversion from a periodically nanostructured metal film显示文摘 | Nahata A Linke R A lshi T | 2003 | Opt Lett2003，28，： | 1 |
| 17 | Hfq structure, function and ligand binding 显示文摘 | Brennan R G Link T M | 2007 | Curr Opin Microbiol2007，10，2： | 1 |
| 18 | Dry beneficiation of Slovakian coal 显示文摘 | Soong Y Link T A Schoffstall M R Gray M L Fauth D J Knoer J P Jones J R Gamwo I K | 2001 | FuelProcessing Technology2001，72，3： | 1 |
| 19 | Biomoleeular sereening with encoded porous-silicon photonie crystals 显示文摘 | Cunin F Sehmedake T A Link J R | 2002 | Nature Mater2002，1，1： | 1 |
| 20 | Pedicle screw instrumentation of the thoracic spine in idiopathic scoliosis显示文摘 | Liljenqvist U R Halm H F Link T M | 1997 | Spine1997，22，： | 1 |
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