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| 1 | Is autoimmune hepatitis a frequent finding among HCV patients with intense interface hepatitis?显示文摘AIM:To evaluate the overlap of autoimmune hepatitis in hepatitis C virus(HCV)-infected patients with intense interface hepatitis.METHODS:Among 1759 patients with hepatitis C submitted to liver biopsy,92(5.2%) presented intense interface hepatitis.These patients were evaluated regarding the presence of antinuclear antibody(ANA),anti-smooth muscle antibody(SMA) and anti-liver/kidney microsomal antibody(LKM-1),levels of γ-globulin and histological findings related to autoimmune hepatitis(plasma cell infiltrate and presence of rosettes).RESULTS:Among patients with hepatitis C and intense interface hepatitis there was a low prevalence of autoantibodies(ANA=12%,SMA=5%,LKM-1=0%) and the median γ-globulin level was within the normal range.Typical histological findings of autoimmune disease were observed in only two cases(2%).After applying the score for diagnosis of autoimmune hepatitis,only one patient was classified with a definitive diagnosis of autoimmune hepatitis.Since overlap with autoimmune hepatitis was not the explanation for the intense necroinflammatory activity in patients with chronic hepatitis C we sought to identify the variables associated with this finding.The presence of intense interface hepatitis was associated with more advanced age,both at the time of infection and at the time of the biopsy,and higher prevalence of blood transfusion and alcohol abuse.CONCLUSION:Although possible,overlap with autoimmune hepatitis is a very rare association in HCV-infected patients with intense interface hepatitis,an unusual presentation which seems to be related to other host variables. | Rosilene G Badiani Vitória Becker Renata M Perez Carla AL Matos Lara B Lemos Valéria P Lanzoni Luis Eduardo C Andrade Alessandra Dellavance Antonio Eduardo B Silva Maria Lucia G Ferraz | 2010 | World Journal of Gastroenterology2010，16，29： | 7 |
| 2 | Formulation of three-dimensional distinct element model, Part Ⅱ, Mechanical calculation of a system composed of many polyhedral blocks 显示文摘 | Hart R Cundall P A Lemos J | 1988 | Int J Rock Mech Min Sci & Geomech Abstr1988，25，3： | 2 |
| 3 | Formulation of a three-dimensional distinct element model--part II: mechanical calculations显示文摘 | HART R D CUNDALL P A LEMOS J V | 1988 | International Journal of Rock Mechanics and Mining Sciences and Geomechanics Abstracts1988，25，3： | 1 |
| 4 | Soluble CD40L:Risk prediction after acute coronary syndromes 显示文摘 | Varo N de Lemos JA Libby P | 2003 | Circulation2003，108，9： | 1 |
| 5 | Formulation of a three- dimensional distinct element model,Part II:Mechanical calculations for motion and interaction of a system composed of many polyhedral blocks显示文摘 | HART R CUNDALL P A LEMOS J | 1988 | International Journal of Rock Mechanics and Mining & Geomechanics1988，25，3： | 1 |
| 6 | Complex quartz growth histories in granite revealed by scanning cathodoluminescence techniques 显示文摘 | D'Lemos R S Kearsley A T Pembroke J W Watt G R Wright P | 1997 | Geology1997，134，4： | 1 |
| 7 | Advances in enhanced biological phosphorus removal: from micro to macro scale 显示文摘 | OEHMEN A LEMOS P C CARVALHO G | 2007 | Water Research2007，41，11： | 1 |
| 8 | Advances in enhanced biological phosphorus removal:from micro to macro scale显示文摘 | Oehmen A Lemos P C Carvalho G | 2007 | Water Research2007，41，11： | 1 |
| 9 | Responses of Stylosanthes humilis (Fabaceae) populations to saline stress显示文摘 | Lovato M B De Lemos Filho J P Martins P S | 1999 | Environmental and Experimental Botany1999，41，： | 1 |
| 10 | 显示文摘 | Dzikh I P Lopes J M Lemos F | 1999 | Appl Catal A1999，176，2： | 1 |
| 11 | Natriuretic peptide hormone measurement in acute coronary syndromes 显示文摘 | Maewal P Lemos J A | 2003 | Heart Fail Rev2003，8，7： | 1 |
| 12 | Migratory and lymphoid-resident dendritic cells cooperate to efficiently prime naive CD4 T cells显示文摘 | Allenspach E J Lemos M P Porrett P M | 2008 | Immunity2008，29，5： | 1 |
| 13 | Scalar, electromagnetic, and Weyl perturbations of BTZ black holes: Quasinormal modes显示文摘 | CARDOSO V LEMOS J P S | 2001 | Phys Rev D2001，63，12： | 1 |
| 14 | 显示文摘 | Dzikh I P Lopes J M Lemos F | 2001 | Catal Today2001，65，24： | 1 |
| 15 | Advances in enhanced biological phosphorus removal:from micro to macro scale显示文摘 | Oehmen A Lemos P C Carvalho G Yuan Z Kelley J Blackall L L Reis M A M | 2007 | Water Research2007，41，11： | 1 |
| 16 | Short-and long-term clinical benefit of sirolimus-eluting stnets compared to conventional bare stents for patients with acute myocardial infarction显示文摘 | SAIA F HOFMA S H | 2004 | J Am Coll Cardiol2004，43，4： | 1 |
| 17 | Elective sirolimus-eluting stent implantation for left main coronary artery disease:six-month angiographic follow-up and 1-year clinical outcome 显示文摘 | ARAMPATZIS C A LEMOS P A HOYE A | 2004 | Catheter Cardiovasc Interv2004，62，3： | 1 |
| 18 | Characterization of specific antibodies against cytomegalovirus(CMV)-encoded interleukin 10 produced by 28%of CMV seropositive blood donors显示文摘 | de Lemos Rieper C Galle P Pedersen B K | 2011 | Journal of Gene Virology2011，92，7： | 1 |
| 19 | Advances in enhanced biological phosphorus removal: from micro to macro scale 显示文摘 | Oehmen A Lemos P C Carvalho G | 2007 | Water Res2007，41，11： | 1 |
| 20 | Soluble CD40L: risk prediction after acute coronary syndromes 显示文摘 | Varo N de Lemos J Libby P | 2003 | Circulation2003，108，9： | 1 |
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