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304篇 您的检索式:作者名="Leach D"
    题名 作者 年代 出处 被引量
1Pancreatic cancer显示文摘Theresa Pluth Yeo Ralph H Hruban Steven D Leach Robb E Wilentz Taylor A Sohn Scott E Kern Christine A Iacobuzio-Donahue Anirban Maitra Michael Goggins Marcia I Canto Ross A Abrams Daniel Laheru Elizabeth M Jaffee Manuel Hidalgo Charles J Yeo 2002Current Problems in Cancer2002,,4:2
2向在人的察觉到钙的受体的 allosteric 药的结构的理解显示文摘allosterically 指向人的察觉到钙的受体(CaSR ) 的药有实质的治疗学的潜力,但是当前被限制。给 CaSR 的高分辨率的结构的缺席,我们把 mutagenesis 与一条新奇分析途径并且开发 “ 的分子的建模相结合; enriched”为在 Ca 2+ 在 CaSRs 7 transmembrane (7TM ) 以内的 o 和 allosteric 调节的人领域。修改多重有约束力的地点以适应在结构上的一个扩大的洞多样的 ligands 被识别。Phenylalkylamines 绑在与通常认为的 Ca 2+ o -binding 地点并且向一个细胞外的门厅延长。相反,在结构上和 pharmacologically 不同的 AC-265347 在 7TM 领域以内更深绑。而且,不同氨基酸网络被发现调停由不同调节的人的 cooperativity。这些调查结果可以与不同、潜在地偏导小径的药理学效果便于 allosteric 调节的人的合理设计。Katie Leach Karen J Gregory Irina Kufareva Elham Khajehali Anna E Cook Ruben Abagyan Arthur D Conigrave Patrick M Sexton Arthur Christopoulos 2016Cell Research2016,26,5:2
3Differential scanning calorimetric studies of muscle and its constituent proteins 显示文摘Wright D J Leach I B Wilding P 1977Journal of the Science of Food and Agriculture1977,28,:1
4Modelling high level system design and unit commitment for a microgrid 显示文摘HAWKES A D LEACH M A 2009Applied Energy2009,86,17:1
5Stability of food allergensto digestion in vitro显示文摘Astwood J D Leach J N Fuchs R L 1996Nat Biotechnol1996,14,:1
6In vitro Cytotoxicity of Australian Tea Tree Oil Using Human Cell Lines显示文摘HAYES A J LEACH D N MARKHAM J L 1997Journal Essential Oil Research1997,9,5:1
7Antioxidant activity of 45 Chinese herbs and the relationship with their TCM characteristics 显示文摘Liao H Banbury L K Leach D N 2003AdvAcc Public2003,85,:1
8Natural variation in the essential oil content of Melaleuca alternifolia Cheel (Myrtaceae)显示文摘Homer L E Leach D N Lea D 2000Biochemical Systematics and Ecology2000,28,:1
9The growth performance,carcass characteristics,and meat quality of halothane carrier and negative pigs显示文摘Leach L M Ellis M Sutton D S 1996Journal of Animal Science1996,74,:1
10A repetitive DNA sequence common to the different B chromosomes of the genus B rachycome显示文摘HOUBEN A Leach C R Verlin D 1997Chromosoma1997,106,:1
11Modelling high level system design and unit commitment for a microgrid显示文摘HAWKES A D LEACH M A 0,,7:1
12Upward So- cial Comparison and Self-concept:Inspiration and Inferiori- ty among Art Student in An Advanced Programme 显示文摘Burleson K C W Leach C W Harrington D M 2005The British Journal of Social Psychology2005,44,1:1
13Mississippi Valley Type Lead-Zinc Deposit through Geolog- ical Time: Implication from Recent Age-dating Research 显示文摘Leach D L 2003Minerali- um Deposita2003,36,:1
14Sulfur-containing compounds in the aroma volatiles of melons ( Cucumis mellon )显示文摘Wyllie S G Leach D H 1992J Agric Food Chem1992,40,:1
15In vitro cytotoxicity of Australian tea tree oil using human cell lines显示文摘 Leach D N Markham J L 1997JEOR1997,9,5:1
16Cadmium and the food chain:The effect of dietary cadmium on tissue composition in chicks and laying hens显示文摘LEACH R WANG K W BAKER D E 1979Nutrition1979,109,:1
17Probe-compensated near-field measurements on a cylinder 显示文摘Leach W M Paris D T 1973IEEE Transactions on Antennas Propagation1973,21,4:1
18Acaricidal and cytotoxic activities of extract from selected genera of Australian Lamiaceae显示文摘Rasikari H L Leach D N Waterman P G 2005Horticultural Entomology2005,98,4:1
19Mississippi valley-type lead-zinc deposits through geological time: implications from recent age-dating research显示文摘Leach D L Bradley D Lewchuk M T 2001Mineralium Deposita2001,36,:1
20Sulfur-containing compounds in the aroma volatiles of melons( Cucumis melo) 显示文摘Wyllie S G Leach D N 1992J Ag- tic Food Chem1992,40,2:1
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