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| 1 | Role of the HLA-DQ locus in the development of chronic gastritis and gastric carcinoma in Mexican patients显示文摘AIM: To determine the HLA-DQ locus in Mexican patients with Chronic gastritis and gastric adenocarcinoma. METHODS: Oligotyping for HLA-DQ locus was performed in 45 Mexican patients with chronic gastritis and 13 Mexican patients with diffuse-type gastric adenocarcinoma, and was then compared with 99 clinically healthy unrelated individuals. H pylori infection and CagA status were assessed in patients by enzyme-linked immunosor-bent assay (ELISA) method. RESULTS: We found a significant increased frequency of HLA-DQB1*0401 allele in H pylori-positive patients with chronic gastritis when compared with healthy subjects [19 vs 0%, P= 1 × 10-7, odds ratio (OR) = 4.96; 95% confidence interval (95% CI), 3.87-6.35]. We also found a significant increased frequency of HLA-DQB1*0501 in patients with diffuse-type gastric carcinoma in comparison with healthy individuals (P = 1 × 10-6, OR = 13.07; 95% CI, 2.82-85.14). CONCLUSION: HLA-DQ locus may play a different role in the development of H pylori-related chronic gastritis and diffuse-type gastric adenocarcinoma in the Mexican Mestizo population. | Roberto Herrera-Goepfert Jesús K Yamamoto-Furusho Luis F Oate-Ocaa Margarita Camorlinga-Ponce Leopoldo Muoz Jorge A Ruiz-Morales Gilberto Vargas-Alarcón Julio Granados Cellular Biology Section | 2006 | World Journal of Gastroenterology2006，12，48： | 4 |
| 2 | A family study of endophenotypes for psychosis within an early intervention programme in Hong Kong: Rationale and preliminary findings显示文摘The study of endophenotypes may be a viable strategy to tackle the genetic complexity and phenotypic heterogeneity of psychosis, but this research direction is relatively under-developed in China as compared to Western countries. We have recently initiated one of the first family studies of endophenotypes for psychosis in China. Patients entering an established early psychosis intervention service are recruited into this research project for phenotyping, endophenotyping and genotyping. At the endophenotypic level, four domains (neurological soft signs, neurocognition of prospective memory, social cognition of facial emotion recognition, and affective cognition of anticipatory and consummatory pleasure) are studied in the sample of patients with psychosis and their unaffected siblings. This article illustrates the benefit of a research-oriented clinical programme and its findings based on the data collected as of early 2011. | LUI Simon S Y SHAM Pak CHAN Raymond C K CHEUNG Eric F C | 2011 | Chinese Science Bulletin2011，56，32： | 2 |
| 3 | 4-and 5-level anterior fusions of the cervical spine:review of literature and clinical results显示文摘 | Heiko K Axel H Luis F | 2007 | Eurp Spine2007，16，12： | 1 |
| 4 | Clinical and genetic heterogeneity in mexican patients with ulcerative colitis显示文摘 | Jesus K Yamamoto F Luis F | 2003 | Human Immunology2003，64，1： | 1 |
| 5 | Semi-defi- nite Programming Algorithms for Sensor Network Node Localization with Uncertainties in Anchor Positions and/ or Propagation Speed 显示文摘 | Lui K W K Ma W K So H C Chan F K W | 2009 | IEEE Transactions on Signal Processing2009，57，2： | 1 |
| 6 | Establishment of a metastatic model of human hepatocellular carcinoma in nude mice via orthotopic implantation of histologically intact tissues显示文摘 | Tang Z Lui K | 1996 | Int J Cancer1996，66，2： | 1 |
| 7 | Establishment of a metastatic model of human hepatocllular carcinoma in nude mice via orthotopic implantation of histologically intact tissues显示文摘 | Sun F X Tang Z Y Lui K D | 1996 | Int J Cancer1996，66，2： | 1 |
| 8 | An analysis of the possible factors contributing to the delayed return of gastric emptying after gastro-jejunostomy 显示文摘 | Kung S P Lui W Y Peng F K | 1995 | Surg Today1995，25，10： | 1 |
| 9 | Thermal response, catalytic activity, and color change of the first hybrid ' vanadate cohtaining bpe guest molecules 显示文摘 | Luis R F Urtiaga M K Mesa j L | 2013 | inorg Chem2013，，52： | 1 |
| 10 | Hysteretic modelsthat incorporate strength and stiffness deterioration显示文摘 | Luis F I Ricardo A M Helmut K | 2005 | Earthquake Engineering and Structural Dynamics2005，34，12： | 1 |
| 11 | Observation of an electrical tunable band gap in trilayer graphene显示文摘 | Lui C Li Z Mak K F | 2011 | Nat Phys2011，7，12： | 1 |
| 12 | Factors associated with sleep disorders in Chinese patients on continuous ambulatory peritoneal dialysis显示文摘 | Lui S L Ng F Lo W K | 2002 | Perit Dial Int2002，22，6： | 1 |
| 13 | Lower uterine segment involvement as a predictor for lymph node spread in endometrial eareinoma显示文摘 | L M Madom A K Brown F Lui | 2007 | Gynecologic Ontology2007，107，： | 1 |
| 14 | Hop-by-hop routing in wireless mesh networks with bandwidth guarantees 显示文摘 | Hou R Lui K S Baker F | 2012 | IEEE Transactions on Mobile Computing2012，11，2： | 1 |
| 15 | Semidefinite programming approachfor range-difference based source localization显示文摘 | Lui K W K1Chan F K W So H C | 2009 | IEEE Transactionson Signal Processing2009，57，4： | 1 |
| 16 | Uhraflat graphene 显示文摘 | LUI C H LIU L MAK K F | 2009 | Nature2009，462，7271： | 1 |
| 17 | All-optical clock recovery using erbium-doped fiber laser incorporating an electroabsorption modulator and a linear optical amplifier显示文摘 | Lui L F K Xu L X Lee C C | 2007 | IEEE Photonics Technology Letters2007，19，10： | 1 |
| 18 | The status of mas- sive transfusion protocols in United States trauma centers: mas- sive transfusion or massive confusion 显示文摘 | Schuster M Davis K A Lui F Y | 2010 | Transfusion2010，50，7： | 1 |
| 19 | Clinical and Genetic Heterogeneity in Mexican Patients With Ulcerative Colitis显示文摘 | JesfJs K Y Luis F U Gilberto Vargas AlarcOn | 2003 | Human hninunology2003，64，1： | 1 |
| 20 | Evaluation of a rapid screening test for micro albuminuria with a spot meusurement of uriaealbumin-creatinine ratio 显示文摘 | Ng W Lui K F Thai A | 2000 | Diabet Med2000，17，1： | 1 |
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