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| 1 | The role of endoscopy in the management of hereditary diffuse gastric cancer syndrome显示文摘Hereditary diffuse gastric cancer(HDGC) syndrome is an inherited cancer risk syndrome associated with path-ogenic germline CDH1 variants. Given the high risk for developing diffuse gastric cancer, CDH1 carriers are recommended to undergo prophylactic total gastrectomy for cancer risk reduction. Current guidelines recommend upper endoscopy in CDH1 carriers prior to surgery and then annually for individuals deferring prophylactic total gastrectomy.Management of individuals from HDGC families without CDH1 pathogenic variants remains less clear, and management of families with CDH1 pathogenic variants in the absence of a family history of gastric cancer is particularly problematic at present. Despite adherence to surveillance protocols, endoscopic detection of cancer foci in HDGC is suboptimal and imperfect for facilitating decision-making. Alternative endoscopic modalities, such as chromoendoscopy,endoscopic ultrasound, and other non-white light methods have been utilized,but are of limited utility to further improve cancer detection and risk stratification in HDGC. Herein, we review what is known and what remains unclear about endoscopic surveillance for HDGC, among individuals with and without germline CDH1 pathogenic variants. Ultimately, the use of endoscopy in the management of HDGC remains a challenging arena, but one in which further research to improve surveillance is crucial. | Shria Kumar Jessica M Long Gregory G Ginsberg Bryson W Katona | 2019 | World Journal of Gastroenterology2019，25，23： | 2 |
| 2 | Three approaches to task-based syllabus design 显示文摘 | Long M & G Grookers | 1992 | TESOL Quarterly1992，192，： | 1 |
| 3 | Isolation and characterization endophytic bacteria from Sedum alfredii Hance and their potential to promote phytoextraction of zinc polluted soil 显示文摘 | LONG X X CHEN X M CHEN Y G WONG J W WEI Z B WU Q T | 2010 | World Journal Microbiology Biotechnology2010，27，： | 1 |
| 4 | CH4-CO2 reforming by plasma-challenges and opportunities显示文摘 | TAO X M BAI M G LI X LONG H L SHANG S Y YIN Y X DAI X Y | | 0，，02： | 1 |
| 5 | Design and performance evaluation of a novel magnetorheological valve with a tunable resistance gap 显示文摘 | HU G LONG M YU L | 2014 | Smart Materials and Structures2014，23，12： | 1 |
| 6 | General scheme for super dense coding between multi-parties 显示文摘 | LIU X S LONG G L TONG D M | 2002 | Phys Rev2002，，02： | 1 |
| 7 | Why peasant's farmers borrow显示文摘 | Long M G | 1968 | American Journal of Agricultural Economics1968，50，4： | 1 |
| 8 | Ethylene inhibits the nod factor signal transduction pathway of Medicago trnncatula显示文摘 | Oldroyd G E D Engstrom E M Long S R | 2001 | Plant Cell2001，13，8： | 1 |
| 9 | Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone(I-34) for 2 years and relevance to human safety显示文摘 | Vahle J L Sato M Long G G | 2002 | Toxicol Pathol2002，30，3： | 1 |
| 10 | More efficient plants:A consequence of rising atmospheric CO2?显示文摘 | Drake B G Gonzalez-Meler M A Long S P | 1997 | Annu Rev Plant Physiol Plant Mol Biol1997，48，： | 1 |
| 11 | Introduction of sense constructs of cinnamate 4-hydroxylase (CYP73A24) in transgenic tomato plants shows opposite effects on flux into stem lignin and fruit flavonoids显示文摘 | Millar D J Long M Donovan G | 2007 | Phytochemistry2007，68，11： | 1 |
| 12 | Introduction of senseconstructs of cinnamate4-hydroxylase (CYP73A24) in transgenic tomato plants shows oppositeeffects on flux into stemlignin and fruitflavonoids显示文摘 | Millar D J Long M Donovan G Fraser P D Boudet A M Danoun S Bramley M and Bolwell G P | | 0，，11： | 1 |
| 13 | Nitrogen-doped ordered mesoporous carbon: synthesis and activesites for electrocatalysis of oxygen reduction reaction 显示文摘 | Wan K Long G F Liu M Y | 2015 | Applied Catalysis B: Environmental2015，165，： | 1 |
| 14 | An Integrative Approach to Assessing the Potential Impacts of Climate Change on the Yunnan Snub - nosed Monkey 显示文摘 | Wong M H G Li R Xu M Long Y | 2013 | Biological Conservation2013，，158： | 1 |
| 15 | Ethylene inhibits the Nod factor signal transduction pathway of Medicago truncatula 显示文摘 | Oldroyd G E D Engstrom E M Long S R | 2001 | The Plant Cell Online2001，13，8： | 1 |
| 16 | Adenovirus-mediated AuroraA shRNA driven by stathmin promoter suppressed tumorgrowth and enhanced paclitaxel chemotherapy sensitivity inhuman breast carcinoma cells 显示文摘 | Long M Yin G Liu L | 2012 | Cancer Gene Ther2012，19，4： | 1 |
| 17 | Fine structure of heating threshold and loudness perception显示文摘 | MAUERMANN M LONG G R KOLLMEIER B | 2004 | Journal of the Acoustical Society of America2004，116，2： | 1 |
| 18 | The political economy of intra-provincial disparities in post-reform China:a case of Jiangsu province显示文摘 | LONG G Y NG M K | 2001 | Geoforum2001，，32： | 1 |
| 19 | More efficient plants: a consequence of rising atmospheric CO2显示文摘 | Drake B G Gonzalez-Meier M A Long S P | 1997 | Annual Reviews of Plant Physiology and Molecular Biology1997，48，： | 1 |
| 20 | Autohydrogenotrophic perehlorate reduction kinetics of a microbial consortium in the presence and absence of nitrate 显示文摘 | London M R de Long S K Strahota M D Katz L E Speitel Jr G E | 2011 | Water Research2011，45，19： | 1 |
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