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| 1 | ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophages显示文摘到巨噬细胞的不同类型的区别决定他们的不同功能。联系肿瘤的巨噬细胞(TAM ) 由于他们的 proangiogenic 和类似于那些的免疫者镇压的功能支持 tumorigenesis 或者激活(M2 ) 巨噬细胞。我们报导那反应的氧种类(ROS ) 生产为巨噬细胞区别和 superoxide 的那抑制是批评的(O 2−) 生产明确地堵住 M2 巨噬细胞的区别。我们发现当单核白血球被触发区分时, O 2− 为 biphasic 英皇家空军之阶级最低之兵激活被产生并且被需要,它为巨噬细胞区别是批评的。我们证明由 butylated hydroxyanisole (BHA ) 和另外的 ROS 禁止者的那 ROS 消除堵住巨噬细胞区别。然而,当房间被极化到时,巨噬细胞区别上的 ROS 消除的禁止的效果被克服古典主义地激活(M1 ) ,然而并非 M2,巨噬细胞。更重要地, ROS 禁止者 BHA 的连续管理高效地堵住了 TAM 的出现并且显著地在老鼠癌症模型压制了 tumorigenesis。由堵住 ROS 指向 TAM 能是为癌症治疗的一个潜在地有效的方法。 | Yan Zhang Swati Choksi Kun Chen Yelena Pobezinskaya Ilona Linnoila Zheng-Gang Liu | 2013 | Cell Research2013，23，7： | 12 |
| 2 | A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies:TTF-1 is expressed in both round and surface cells,suggesting an origin from primitive respiratory epithelium显示文摘 | Devouassoux-shisheboran M Hayashi T Linnoila RI | 2000 | Am J Surg Pathol2000，24，7： | 1 |
| 3 | A clinicopathologic study of 100 cases of puhnonary sclerosing bemangioma with immunohistochemical studies: TTF - 1 is expressed in both round and surface cells, Suggesting an orgin from primitive respiratory epithelium 显示文摘 | Devouassou - Shisheoran M Hayashi T Linnoila RI | 2000 | Am J Surg Pathol2000，24，： | 1 |
| 4 | A clinicopathologic study of 100 cases pulmonary sclerosing hemangioma with immunohistochemical studies显示文摘 | Devouassoux SM Hayashi T Linnoila RI | | 0，，： | 1 |
| 5 | A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies:TTF-1 is expressed in both round and surface cells,suggesting an origin from primitive respiratory epithelium显示文摘 | Hayashi T Linnoila RI | 2000 | Am J Surg Pathol2000，24，7： | 1 |
| 6 | An achaete-scute hom-ologue essential for neuroendocrine differentiation in the lung显示文摘 | Borges M Linnoila RI van de Velde HJ | 1997 | Na-ture1997，386，6627： | 1 |
| 7 | A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies:TTF-1 is expressed in both round and surface cells,suggesting an origin from primitive respiratory epithelium显示文摘 | Devouassoux-Shisheboran M Hayashi T Linnoila RI | 2000 | Am J Surg Pathol2000，24，7： | 1 |
| 8 | Tobacco carcinogen-induced cellular transformation increases activation of the phosphatidylinositol 3'-kinase/Akt pathway in vitro and in vivo显示文摘 | West KA Linnoila IR Belinsky SA | 2004 | Cancer Res2004，64，2： | 1 |
| 9 | The role of CC10 in Pulmonary carcinogenesis: From a marker to tumor suppression显示文摘 | Linnoila RI Szabo E Demayo F | 2000 | Ann N Y Acad sci2000，923，： | 1 |
| 10 | Two naturally occurring amino acid substitutions in the human 5-HT1A receptor:glycine 22 to serine 22 and isoleucine 28 to valine 28显示文摘 | Nakhai B Nielsen DA Linnoila M Goldman D | | 0，，： | 1 |
| 11 | Evidence for neural origin and PAS-positive variants of the malignant small cell tumor of thoracopulmonary region ( ' Askin tumor')显示文摘 | Linnoila RI Tsokos M Triche TJ | 1986 | Am J Surg Pathol1986，10，： | 1 |
| 12 | A clinicopathologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies: TF-1 is expressed in both round and surface cells, suggesting an origin from primitive respiratory epithelium显示文摘 | Devouassoux-Shisheboran M H ayashi T Linnoila RI | 2000 | Am J Surg Pathol2000，24，7： | 1 |
| 13 | A clinicopatbologic study of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies: TTF-1 is expressed in both round and surface cells, suggesting an origin from primitive respiratory epithelium 显示文摘 | Devouassoux-Shishehoran M Hayashi T Linnoila R I | 2000 | Am J Surg Pathol2000，24，7： | 1 |
| 14 | Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells 显示文摘 | West KA Brognard J Clark AS Linnoila IR Yang X Swain SM | 2003 | JClinlnvest2003，111，1： | 1 |
| 15 | A clinicopathologic study of 100cases of pulmonary sclerosing hemangioma with immunohistochemical studies: TTF-1 isexpressed in both round and surface cells, suggesting an origin from primitive respiratoryepithelium显示文摘 | Devouassoux-Shisheboran M Hayashi T Linnoila RI | 2000 | American Journal of Surgical Pathology2000，24，7： | 1 |
| 16 | A clinicopathologic studies of 100 cases of pulmonary sclerosing hemangioma with immunohistochemical studies 显示文摘 | Devouassoux-Shisheboran M Hayashi T Linnoila R I | 2000 | Am J Surg Pathol2000，24，： | 1 |
| 17 | Low cerebrospinal fluid 5-hydroxyindoleacetic acid concentration differentiates impulsive from nonimpulsive violent behaviour显示文摘 | Linnoila M Virkkunen M Scheinin M | 1983 | Life Sci1983，33，： | 1 |
| 18 | A clinicopathologic studies of 100 cases of pulmonary sclerosing hemangioma with immunohisto-chemical studies显示文摘 | Devouassoux-Shisheboran M Hayashi T Linnoila RI | 2000 | Am J SurgPathol2000，24，7： | 1 |
| 19 | Impact of neuroendocrine differentiation in non-small-cell lung cancer:the LCSG experience显示文摘 | Linnoila RI Piantadosi S Ruckdeschel JC | 1994 | Chest1994，106，6： | 1 |
| 20 | Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model显示文摘 | MEUWISSEN R LINN S C LINNOILA R I | 2003 | Cancer Cell2003，4，3： | 1 |
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