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| 1 | Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis显示文摘Background Stroke is a major cause of death or long-term disability worldwide.Many patients with stroke receive integrative therapy consisting of Western medicine(WM)and routine rehabilitation in conjunction with Chinese medicine(CM),such as acupuncture and Chinese herbal medicine.However,there is no available evidence on the effectiveness of the combined use of WM and CM interventions in stroke rehabilitation.Aims The purpose of this meta-analysis is to evaluate the results of all individual studies to assess the combined use of CM and WM in stroke rehabilitation compared with WM only.Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines were followed.MEDLINE,EMBASE,Cochrane and China National Knowledge Infrastructure(CNKI)were searched.The included outcomes were dependency,motor function,depression and swallowing function.Subgroup analysis was performed,and publication bias was assessed using funnel plots.Summary of review 58 studies and 6339 patients were included in the meta-analysis.Subgroup analysis revealed that combined therapy comprising both acupuncture and WM had a superior effect on improving dependency and swallowing function compared with standard WM therapy alone.Potential superiority of combined therapy comprising CM and WM in improving depression compared with standard WM therapy was also found.Conclusions Our results indicate that the combined use of CM and WM could be more efficacious in stroke rehabilitation compared with the use of WM therapy alone.However,most studies were short in duration(2 to 4 weeks)and prone to different types of biases,which prevents making any conclusion regarding the long-term effects and raises concerns regarding true efficacy in context of high likelihood of Hawthorn bias.So,more randomised controlled trials with more rigorous design and longer duration of treatment and follow-up need to be conducted to compare WM alone versus WM and CM combined. | Linda LD Zhong Ya Zheng Alexander Y Lau Norman Wong Liang Yao Xingyao Wu Tengteng Shao Zhenxing Lu Huijuan Li Chun Sum Yuen Jianwen Guo Suzanne Lo Janita Chau Kam Wa Chan Bacon Fung Leung Ng Zhaoxiang Bian Edwin Chau-leung Yu | 2022 | Stroke & Vascular Neurology2022，7，1： | 7 |
| 2 | Alveolar type Ⅱ cell growth on a pulmonary endothelial extracellular matrix 显示文摘 | Linda Y | 1996 | Am J Physiol1996，270，14： | 1 |
| 3 | The formulation of aptamer-coated paclitaxel-polylactide nanoconjugates and their targeting to cancer cells 显示文摘 | Rong T Linda Y Timothy M F | 2010 | Biomaterials2010，31，： | 1 |
| 4 | Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial显示文摘 | George L Bakris Pantelis A Sarafidis Matthew R Weir Bj?rn Dahl?f Bertram Pitt Kenneth Jamerson Eric J Velazquez Linda Staikos-Byrne Roxzana Y Kelly Victor Shi Yann-Tong Chiang Michael A Weber | 2010 | The Lancet2010，，9721： | 1 |
| 5 | Antimicrobial activities of cinnamon oil and cinnamaldehyde from the Chinese medici- nal herb cinnamorrum cassia blume 显示文摘 | Linda S M O Li Y L Kam S L | 2006 | The American Jour- nal of Chinese Medicine2006，34，3： | 1 |
| 6 | Endothelin-1 regulates proliferative responses, both alone and synergistically with PDGF, in rat tracheal smooth muscle cells 显示文摘 | Linda Y Annie V Hector V-C | 2006 | Cell Physiol Biochem2006，17，12： | 1 |
| 7 | Mutations in FIE,a WD polycomb group gene,allow endosperm developmen with fertilization显示文摘 | NIR O RAMIN Y LINDA M | 1999 | Plant Cell1999，11，： | 1 |
| 8 | Report of the counciL on scientific affairs biohazardous waste management: What the physician needs to know 显示文摘 | Linda C Scott D D DonaLd C Y | 2001 | ARCH FAM MED2001，，9： | 1 |
| 9 | Mapping struc- tual to function damage in glaucoma with standard automated perimetry and confocal scanning laser ophthalmoscopy显示文摘 | ALFONSO A NORIKO Y LINDA Z | 1998 | Am J Opthalmol1998，125，： | 1 |
| 10 | An algorithm for vector quantizer design 显示文摘 | Linda Y Buzo A Gray R M | 1980 | IEEE Transactions on Communications1980，28，1： | 1 |
| 11 | Intrathecal triple therapy decreases central nervous system reeapse but fails to improve enent-free survival when compared with intrathecal methotrexate:results of the Children's Cancer Group(CCG)1952 study for standardrisk acute lymphoblastic leukemia,reported by the Children's Oncology Group显示文摘 | MATLOUB Y LINDEMULDER S Linda C S | 2006 | Blood2006，108，6： | 1 |
| 12 | Using the Roy Adaptation Model to develop an antenatal assessment instrument显示文摘 | Linda L Alan Y Ka Fai W | 2011 | Nursing Science Quarterly2011，24，4： | 1 |
| 13 | Echovirus type 11:outbreak of hand-foot-and-mouth disease in a Thai hospital nursery显示文摘 | Apisamthanarak K Kitphati R Pongsuwann Y Tacharoenmueng R Linda M | 2005 | Clin Infect Dis2005，41，9： | 1 |
| 14 | Increasing hydrophobicity of sol-gel hard coating by chemical and morphological modifications显示文摘 | Wu Linda Y L Soutar A M Zeng X T | 2005 | Surface and Coatings Technology2005，198，： | 1 |
| 15 | Recent developments in forward osmosis: Opportunities and challenges显示文摘 | Shuaifei Zhao Linda Zou Chuyang Y Tang | | Joumal of Membrane Scienec0，396，： | 1 |
| 16 | Mapping structural to function damage in glaucoma with standard automated perimetry and confocal scanning laser ophthalmoscopy显示文摘 | Alfonso A Noriko Y Linda Z | 1998 | Am J Ophthalmol1998，125，： | 1 |
| 17 | Patent Laws and Innovation in China显示文摘 | Linda Y | | 0，，09： | 1 |
| 18 | Decision mode,information and network attachment in theinternationalization of SMEs:A configurational and contingency analysis显示文摘 | JOHN CHILD LINDA H Y HSIEH | 2014 | Journal of World Business2014，，1： | 1 |
| 19 | Thymosin alphat 显示文摘 | David CA Jerry P Linda Y | 2001 | Am J Health Syst Pharm2001，58，15： | 1 |
| 20 | Vascular endothelial growth inhibitor (VEGI), an endogenous negative regu- lator of angiogenesis显示文摘 | Metheny-Barlow Linda J Li L Y | 2006 | Semin Ophthalmol2006，21，1： | 1 |
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