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| 1 | Comparison of high-resolution ultrasound and MR-enterography in patients with inflammatory bowel disease显示文摘AIM:To compare the results of high-resolution ultrasound(HR-US) and magnetic resonance enterography(MRE) examinations in patients with inflammatory bowel disease(IBD).METHODS:The reports of 250 consecutive cases with known IBD,who had an MRE and HR-US examination,were retrospectively analyzed.Using a patient-based approach we evaluated morphological disease features such as affected bowel wall,stenosis,abscess and fistula.The comparison between the two modalities was based on the hypothesis,that any pathological change described in any imaging modality was a true finding,as no further standard of reference was available for complete assessment.RESULTS:Two hundred and fifty examinations representing 207 different patients were evaluated.Both modalities assessed similar bowel wall changes in 65% of the examinations,with more US findings in 11% and more MRE findings in 15%.When the reports were analyzed with regard to 'bowel wall inflammation',US reported more findings in 2%,while MRE reported more findings in 53%.Stenoses were assessed to be identical in 8%,while US found more in 3% and MRE in 29%(P < 0.01).For abscess detection,US showed more findings in 2%(n = 4) while MRE detected more in 6%(n = 16).US detected more fistulas in 1%(n = 2),while MRE detected more in 13%(n = 32)(P < 0.001).The most common reason for no detected pathology by US was a difficult to assess anatomical region(lesser pelvis,n = 72).CONCLUSION:US can miss clinically relevant pathological changes in patients with IBD mostly due to difficulty in assessing certain anatomical regions. | Andreas G Schreyer Cynthia Menzel Chris Friedrich Florian Poschenrieder Lukas Egger Christian Dornia Gabriela Schill Lena M Dendl Doris Schacherer Christl Girlich Ernst-Michael Jung | 2011 | World Journal of Gastroenterology2011，17，8： | 7 |
| 2 | Dynamic magnetic resonance defecography in 10 asymptomatic volunteers显示文摘AIM: Evaluation of the wide range of normal findings in asymptomatic women undergoing dynamic magnetic resonance (MR) defecography. METHODS: MR defecography of 10 healthy female volunteers (median age: 31 years) without previous pregnancies or history of surgery were evaluated. The rectum was filled with 180 mL gadolinium ultrasound gel mixture. MR defecography was performed in the supine position. The pelvic floor was visualized with a dynamic T2-weighted sagittal plane where all relevant pelvic floor organs were acquired during defecation. The volunteers were instructed to relax and then to perform straining maneuvers to empty the rectum. The pubococcygeal line (PCGL) was used as the line of reference. The movement of pelvic floor organs was measured as the vertical distance to this reference line. Data were recorded in the resting position as well as during the defecation process with maximal straining. Examinations were performed and evaluated by two experienced abdominal radiologists without knowledge of patient history. RESULTS: Average position of the anorectal junction was located at -5.3 mm at rest and -29.9 mm during straining. The anorectal angle widened significantly from 93° at rest to 109° during defecation. A rectocele was diagnosed in eight out of 10 volunteers showing an average diameter of 25.9 mm. The bladder base was located at a position of +23 mm at rest and descended to -8.1 mm during defecation in relation to the PCGL. The bladder base moved below the PCGL in six out of 10 volunteers, which was formally defined as a cystocele. The uterocervical junction was located at an average level of +43.1 mm at rest and at +7.9 mm during straining. The uterocervical junction of three volunteers fell below the PCGL; described formally as uterocervical prolapse. CONCLUSION: Based on the range of standard values in asymptomatic volunteers, MR defecography values for pathological changes have to be re-evaluated. | Andreas G Schreyer Christian Paetzel Alois Fürst Lena M Dendl Elisabeth Hutzel René Müller-Wille Philipp Wiggermann Stephan Schleder Christian Stroszczynski Patrick Hoffstetter | 2012 | World Journal of Gastroenterology2012，18，46： | 7 |
| 3 | Central nervous system cavernomas in children显示文摘 | Lena G Temier J Paz-Paredes A | 2007 | Neurochirurgie2007，53，232： | 1 |
| 4 | Lung macrophages and dendritic cells express HLA - G molecules in pulmonary diseases 显示文摘 | Pangault C Le Friec G Caulet - Maugendre S Lena H Amiot L Guilloux V Onno M Fauchet R | 2002 | Hum Immunol2002，63，2： | 1 |
| 5 | Investigating the factors affecting blood donation among Israelis显示文摘 | Merav B N Lena G | 2011 | Int Emerg Nuts2011，，19： | 1 |
| 6 | Chromatin remodelling during develop- ment 显示文摘 | Lena H Crabtree G R | 2010 | Nature2010，463，7280： | 1 |
| 7 | MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines显示文摘 | Viticchie G Lena AM Latina A | 2011 | Cell Cycle2011，10，7： | 1 |
| 8 | MieroRNA-203 eontri- bules to skin re-epithelialization 显示文摘 | Vitieehi G Lena AM Cianfarani F el al | 2012 | Cell Death Dis2012，3，： | 1 |
| 9 | Craniopharyngioma in children:marseille experience显示文摘 | Lena G Paz Paredes A Scavarda D | 2005 | Childs Nerv Syst2005，21，8： | 1 |
| 10 | Evaluation of 138 fractures of the cervical spine during a recent 5 - year- period( 1979-983 ) : therapentic approaches显示文摘 | Reynier Y Lena G Vazqnez P | 1985 | Nearo - chirargic1985，31，2： | 1 |
| 11 | Brainstem tumors 显示文摘 | Choux M Lena G Do L | 2000 | Pediatric Neurosurgery2000，33，： | 1 |
| 12 | Phase I and preliminary phase Ⅱ evaluation of adriamycin 显示文摘 | Bonadonna G Monfardin S Lena MD | 1970 | Cancer Res1970，30，11： | 1 |
| 13 | MiR-203 controlsproliferation, migration and invasive potential of prostatecancer cell lines 显示文摘 | Viticchie G Lena AM Latina A | 2011 | Cell Cycle2011，10，7： | 1 |
| 14 | MiR-203 controls prolifera-tion,migration and invasive potential of prostate cancer cell lines显示文摘 | ViticchièG Lena AM Latina A | 2011 | Cell Cycle2011，10，7： | 1 |
| 15 | The surgery of occult spinal dysraphism显示文摘 | Choux M Lena G Genitori L | 1994 | Adv Tech Stand Neurosurg1994，21，： | 1 |
| 16 | Growth,nutritional quality and safety of oysters(Crassostrea gigas)cultured in the lagoon of Venice(Italy)显示文摘 | Orban E Di Lena G Masci M Nevigato T Casini I Caproni R | | 0，，： | 1 |
| 17 | Organic acid mediated P mobilization in the rhizosphere and uptake by maize roo ts显示文摘 | Lena S Andrew G O Douglas L G | 2002 | Soil Biology Biochemistry2002，34，5： | 1 |
| 18 | Outcomes following liver transplantation in intensive care unit patients显示文摘AIM:To determine feasibility of liver transplantation in patients from the intensive care unit (ICU) by estimating graft and patient survival.METHODS:This single center retrospective study included 39 patients who had their first liver transplant directly from the intensive care unit and 927 non-ICU patients who were transplanted from hospital ward or home between January 2005 and December 2010.RESULTS:In comparison to non-ICU patients,ICU patients had a higher model for end-stage liver disease (MELD) at transplant (median:37 vs 20,P < 0.001).Fourteen out of 39 patients (36%) required vasopressor support immediately prior to liver transplantation (LT) with 6 patients (15%) requiring both vasopressin and norepinephrine.Sixteen ICU patients (41%) were ventilator dependent immediately prior to LT with 9 patients undergoing percutaneous tracheostomy prior to transplantation.Twenty-five ICU patients (64%) required dialysis preoperatively.At 1,3 and 5 years after LT,graft survival was 76%,68% and 62% in ICU patients vs 90%,81% and 75% in non-ICU patients.Patient survival at 1,3 and 5 years after LT was 78%,70% and 65% in ICU patients vs 94%,85% and 79% in non-ICU patients.When formally comparing graft survival and patient survival between ICU and nonICU patients using Cox proportional hazards regression models,both graft survival [relative risk (RR):1.94,95%CI:1.09-3.48,P=0.026] and patient survival (RR:2.32,95%CI:1.26-4.27,P=0.007) were lower in ICU patients vs non-ICU patients in single variable analysis.These findings were consistent in multivariable analysis.Although not statistically significant,graft survival was worse in both patients with cryptogenic cirrhosis (RR:3.29,P=0.056) and patients who received donor after cardiac death (DCD) grafts (RR:3.38,P=0.060).These findings reached statistical significance when considering patient survival,which was worse for patients with cryptogenic cirrhosis (RR:3.97,P=0.031) and patients who were transplanted with DCD livers (RR:4.19,P=0.033).Graft survival and patient survival were not significantly worse for patients on mechanical ventilation (RR:0.91,P=0.88 in graft loss;RR:0.69,P=0.56 in death) or patients on vasopressors (RR:1.06,P=0.93 in graft loss;RR:1.24,P=0.74 in death) immediately prior to LT.Trends toward lower graft survival and patient survival were observed for patients on dialysis immediately before LT,however these findings did not approach statistical significance (RR:1.70,P=0.43 in graft loss;RR:1.46,P=0.58 in death).CONCLUSION:Although ICU patients when compared to non-ICU patients have lower survivals,outcomes are still acceptable.Pre-transplant ventilation,hemodialysis,and vasopressors were not associated with adverse outcomes. | Lena Sibulesky Michael G Heckman C Burcin Taner Juan M Canabal Nancy N Diehl Dana K Perry Darren L Willingham Surakit Pungpapong Barry G Rosser David J Kramer Justin H Nguyen | 2013 | World Journal of Hepatology2013，5，1： | 1 |
| 19 | Starvation response of Saccharomyces cerevisiae grown in anaerobic nitrogen-or carbon- limited Chemostat Cultures显示文摘 | Elisabeth T Lena G Christer L | 2005 | Applied And Environmental Microbiology2005，，7： | 1 |
| 20 | Seasonal changes in meat content, condition index and chemical composition of mussels (Mytilus galloprovincialis) cultured in two different Italian sites显示文摘 | ORBAN E di LENA G NEVIGATO T | 2002 | Food Chemistry2002，77，1： | 1 |
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