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| 1 | Vleiotic recombination and male infertility: from basic science to clinical reality?显示文摘 | Michael Chann Patricio E Lau Helen G Tempest | 2011 | Asian Journal of Andrology2011，13，2： | 6 |
| 2 | Tumor necrosis factor-α-induced protein 1 and immunity to hepatitis B virus显示文摘AIM: To compare the gene expression profile in a pair of HBV-infected twins.METHODS: The gene expression profile was compared in a pair of HBV-infected twins.RESULTS: The twins displayed different disease outcomes. One acquired natural immunity against HBV,whereas the other became a chronic HBV carrier. Eightyeight and forty-six genes were found to be up- or downregulated in their PBMCs, respectively. Tumor necrosis factor-alpha-induced protein 1 (TNF-αIP1) that expressed at a higher level in the HBV-immune twins was identified and four pairs of siblings with HBV immunity by RTPCR. However, upon HBV core antigen stimulation,TNF-αIP1 was downregulated in PBMCs from subjects with immunity, whereas it was slightly upregulated in HBV carriers. Bioinformatics analysis revealed a K+channel tetramerization domain in TNF-αIP1 that shares a significant homology with some human, mouse, and C elegan proteins.CONCLUSION: TNF-αIP1 may play a role in the innate immunity against HBV. | Marie C Lin Nikki P Lee Ning Zheng Pai-Hao Yang Oscar G Wong Hsiang-Fu Kung Chee-Kin Hui John M Luk George Ka-Kit Lau | 2005 | World Journal of Gastroenterology2005，11，48： | 3 |
| 3 | Acute appendicitis–advances and controversies显示文摘Being one of the most common causes of the acute abdomen,acute appendicitis(AA)forms the bread and butter of any general surgeon’s practice.With the recent advancements in AA’s management,much controversy in diagnostic algorithms,possible differential diagnoses,and weighing the management options has been generated,with no absolute consensus in the literature.Since Alvarado described his eponymous clinical scoring system in 1986 to stratify AA risk,there has been a burgeoning of additional scores for guiding downstream management and mortality assessment.Furthermore,advancing literature on the role of antibiotics,variations in appendicectomy,and its adjuncts have expanded the surgeon’s repertoire of management options.Owing to the varied presentation,diagnostic tools,and management of AA have also been proposed in special groups such as pregnant patients,the elderly,and the immunocompromised.This article seeks to raise the critical debates about what is currently known about the above aspects of AA and explore the latest controversies in the field.Considering the ever-evolving coronavirus disease 2019 situation worldwide,we also discuss the pandemic’s repercussions on patients and how surgeons’practices have evolved in the context of AA. | Thomas Zheng Jie Teng Xuan Rong Thong Kai Yuan Lau Sunder Balasubramaniam Vishal G Shelat | 2021 | World Journal of Gastrointestinal Surgery2021，13，11： | 2 |
| 4 | Global Nanoteehnology Research Literature Overview显示文摘 | Kostoff R N Koytcheff R G Lau C G Y | 2007 | Current Science2007，，11： | 1 |
| 5 | High level expression of hepatitis B viral antigens in fibrosing cholestatic hepatitis 显示文摘 | Lau J Y N Davis GL Bain V G | 1992 | Gastroenterology1992，102，： | 1 |
| 6 | EASL International Consensus Conference on Hepatitis B 显示文摘 | De Franehis R Hadengue A Lau G | 2003 | J Hepatol2003，39，： | 1 |
| 7 | Enhancement of nearband-edge photoluminescence from ZnO films by face-to-face annealing显示文摘 | Wang Y G Lau S P Zhang X H | 2003 | J Crystal Gruth2003，259，： | 1 |
| 8 | Hot-wire chemical vapor deposition (HWCVD) of fluorocarbon and organosilicon thin films显示文摘 | Lau K K S Lewis H G P Limb S J | 2001 | Thin Solid Films2001，395，12： | 1 |
| 9 | Polycrystalline ZnO thin films on Si (100) deposited by filtered cathodic vacuum arc 显示文摘 | XU X L LAU S P CHEN J S CHEN G Y TAY B K | 2001 | Journal of Crystal Growth2001，223，12： | 1 |
| 10 | The antile-ukemia effect of HLA - matched NK and NK - T cells in chronicmyelogenous leukemia involves NKG2D - target - cell interactions显示文摘 | SCONOCCHIA G LAU M PROVENZANO M | 2005 | Blood2005，106，10： | 1 |
| 11 | Melt strength ofpolypropylene : its relevance to thermoforming 显示文摘 | LAU H C BHATACHARYA S N FIELD G J | 1998 | PolymerEngineering Science1998，38，11： | 1 |
| 12 | lInterleukin-10 treatment reduces fibrosis inpatients with chronic hepatitis C:A pilottrail of interferon nonresponders显示文摘 | Nelson D R Lauwers G Y Lau J Y | 2000 | Gas-troenterology2000，118，4： | 1 |
| 13 | Characterization of monoclonal antibody against SARS coronavirus nulceocapsid antigen and development of an antigen capture ELISA显示文摘 | He Q G Du Q Y Lau S L | 2005 | J Virol Meth2005，127，： | 1 |
| 14 | Chaos game representation of protein sequences based on the detailed HP model and their muhifractal and correlation analyses 显示文摘 | YU Z G Anh V Lau K S | 2004 | Journal of Theoretical Biology2004，226，： | 1 |
| 15 | Consumers' trust in a brand and the link to brand loyalty 显示文摘 | LAU G T LEE S H | 1999 | Journal of Market-Focused Management1999，4，4： | 1 |
| 16 | Ionic liquids: Current developments, potential and drawbacks for industrial applications显示文摘 | LAUS G BENTIVOGLIO G SCHOTTENBERGER H KAHLENBERG V KOPACKA H RODER T SIXTA H | 2005 | Lenzinger Berichte2005，84，： | 1 |
| 17 | Dextrocardia-value of segmental analysis in its categorization 显示文摘 | CALCATERRA G ANDERSON R H LAU K C | 1979 | Br Heart J1979，42，： | 1 |
| 18 | Structural,electrical and optical properties of Al-doped ZnO thin films prepared by filtered catholic vacuum are technique显示文摘 | LEE H W LAU S P WANG Y G | 2004 | Journal of Crystal Growth2004，268，34： | 1 |
| 19 | Photoluminescence study of ZnO films prepared by thermal oxidation of Zn metallic films in air显示文摘 | Wang Y G Lau S P Lee H W | | Journal of Applied Physics0，94，1： | 1 |
| 20 | An abundant class of tinyRNAs with probable regulatory roles in Caenorhabditis elegans显示文摘 | LAU N C LIM L P WEINSTEIN E G | 2001 | ScienceSignaling2001，294，5543： | 1 |
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