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| 1 | Anti-microbial principles of selected remedial plants from Southern India显示文摘Objective:To examine the anti-bacterial activity of leaf extracts of Morus alba L.(Moraceae)and Piper betel L.(Piperaceae),and seed extracts of Bombax ceiba L.(Borabacaceae).Methods:We have partially purified plant extracts by solvent extraction method,and evaluated the effect of individual fractions on bacterial growth using Escherichia coli(E.coli),Pseudomonas aeruginosa(P.aeruginosa) and Staphylococcus aureus(S.aureus) bacterial strains.Results:Compared with Morus and Bombax fractions,Piper fractions showed significant growth inhibition on all the three types of bacteria studied.The EtOAc-hexane fractions of Piper leaves exhibited significant antibacterial activity with minimum inhibitory concentrations(MIC) of 50 μg/mL culture against both gram-positive and gram-negative bacteria.The EtOAc-fractions Ⅰ,Ⅱ,and Ⅳ inhibited bacterial colony formation on soft agar in addition to growth inhibition.A combination treatment of piper fractions with ampicillin resulted in significant growth inhibition in E.coli and P.aeruginosa,and combination with anticancer drug geldanamycin(2 μg/mL) showed selective growth inhibition against P.aeruginosa and S.aureus.Three major compounds,i.e.,eugenol,3-hexene-ol and stigmasterol,were primarily identified from Piper betel leaf extractions.Among the individual compounds,eugenol treatment showed improved growth inhibition compared with stigmasterol and 3-hexene-ol.Conclusions:We are reporting potential anti-bacterial compounds from Piper betel against both gram-positive and gram-negative bacteria either alone or in combination with drug treatment. | Tirupathi Rao G Suresh Babu K J Ujwal Kumar Sujana P A Veerabhadr Raoa Sreedhar AS | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，4： | 5 |
| 2 | IL 28 B genotype is not useful for predicting treatment outcome in A sian chronic hepatitis B patients treated with pegylated interferon‐α显示文摘 | Jacinta A Holmes Tin Nguyen Dilip Ratnam Neel M Heerasing Jane V Tehan Sara Bonanzinga Anouk Dev Sally Bell Stephen Pianko Robert Chen Kumar Visvanathan Rachel Hammond David Iser Ferry Rusli William Sievert Paul V Desmond D Scott Bowden Alexander J Thomps | 2013 | J Gastroenterol Hepatol2013，，5： | 2 |
| 3 | Gastric hyperplastic polyps causing upper gastrointestinal hemorrhage in a young adult显示文摘Here, we report a case of a young man who presented with a significant upper gastrointestinal bleed treated by endoscopic removal of multiple hyperplastic polyps. Gastric hyperplastic polyps are a relatively uncommon cause of overt gastrointestinal bleeding. While most hyperplastic gastric polyps are asymptomatic, they may present with abdominal pain, iron def iciency anemia or gastric outlet obstruction. These polyps are associated with conditions such as Helicobacter pylori gastritis and atrophic autoimmune gastritis, which predispose the epithelium to chronic inf lammation and epithelial repair.The patient presented to Northwestern Memorial Hospital in July 2011. The polyps were resected by clip-assisted snare polypectomy. Histopathologic assessment of the resected polyps demonstrated multiple, nonulcerative hyperplastic polyps measuring 1.3-1.8 cm in size, without evidence of dysplasia or malignancy. This case describes a young adult patient with multiple, large gastric polyps causing overt gastrointestinal bleeding. This is a rare presentation in a young individual, as these polyps are typically identifi ed in patients older than 60 years of age and less commonly, pediatric populations. | Brian J Secemsky Kenika R Robinson Kumar Krishnan Kristina A Matkowskyj Barbara H Jung | 2013 | World Journal of Clinical Cases2013，1，1： | 2 |
| 4 | A comparison of seven soil P tests for plant species with different external P requirements grown on soils containing rock phosphate and superphosphate residues 显示文摘 | KUMAR V GILKES R J BOLLAND M D A | 1993 | Fertiliser Research1993，33，： | 1 |
| 5 | Low Complexity Decimation Filters for Multi-standard Digital Receivers显示文摘 | Xihuitl J Kumar A Bayoumi M | 2005 | IEEE International Symposium on Circuits and Systems2005，4，1： | 1 |
| 6 | Differences among H1 Histone Subfractions in Binding to Linear and Superhelical DNA显示文摘 | Alva K S Kumar J Marx K A | 1981 | J Biol Chem1981，256，11： | 1 |
| 7 | On the fundamental tradeoffs between routing table size and network diameter in peer-to-peer networks显示文摘 | J Xu A Kumar | 2004 | IEEE Journal on Selected Areas in Communications (JSAC)2004，22，1： | 1 |
| 8 | 显示文摘 | Singh R Kumar J Kaur A | 2006 | Polymer2006，47，： | 1 |
| 9 | Solvent extraction of Hf(IV) from acidic chloride solutions using Cyanex 302显示文摘 | REDDY B R KUMAR J R RAJA K P REDDY A V | 2004 | Minerals Engineering2004，17，： | 1 |
| 10 | Benzoyl Cyanide: A Mild and Efficient Reagent for Benzoylation of Nucleosides 显示文摘 | PRASAD A K KUMAR V MAITY J | 2005 | Synthetic Communications2005，35，： | 1 |
| 11 | Clinical review : myocardial depres- sion in sepsis and septic shock显示文摘 | Court O Kumar A Parrillo J | 2000 | CritCare2000，6，3： | 1 |
| 12 | Resistance to chemotherapy is associated with fibroblast growth factor receptor 4 up-regulation显示文摘 | Roidl A Berger H J Kumar S | 2009 | Clin Cancer Res2009，15，6： | 1 |
| 13 | Ceria added Sb-V2O5/ TiO2 catalysts for low temperature NH3 SCR: Physico-chemical properties and catalytic activity 显示文摘 | Lee K J Kumar P A Maqbool M S | 2013 | Applied Catalysis B : Environ- mental2013，，： | 1 |
| 14 | High diversity andwidespread occurrence of mitotic spore mats in ectomycorrhizalPezizales显示文摘 | Healy R A Smith M E Bonito G M Pfister D H Ge Z W Guevara G G ’ Williams G Stafford K Kumar L Lee T HobartC Trappe J Vilgalys R McLaughlin D J | 2013 | Molecular Ecology2013，22，： | 1 |
| 15 | Plant retrotransposon显示文摘 | KUMAR A BENNETZEN J L | 1999 | Annu Rev Genet1999，33，： | 1 |
| 16 | Plasticity and reprogramming of differentiated cells in amphibian regeneration显示文摘 | Brockes J P Kumar A | 2002 | Nat Rev Mol Cell Biol2002，，3： | 1 |
| 17 | Innate immune response of corneal epithelial cells to Staphylococcus aureus infection:role of peptidoglycan in stimulating proinflammatory cytokine secretion显示文摘 | Kumar A Zhang J Yu F S | 2004 | Invest Ophthalmol Vis Sci2004，45，10： | 1 |
| 18 | Achieving High Robustness in Supply Distribution Networks by Rewiring 显示文摘 | Zhao K Kumar A Yen J | 2011 | IEEE Transactions on Engineering Management (S0018-9391)2011，58，2： | 1 |
| 19 | Dermatomyositis associated with acute myelocytic leukemia 显示文摘 | Shrivastav A Kumar V Pal J | 2010 | Rheumatol Int2010，30，5： | 1 |
| 20 | Nanoparticles in the Indian environment: known, unknowns and awareness 显示文摘 | KUMAR P KUMAR A LEAD J R | 2012 | Environmental Science & Technology2012，46，： | 1 |
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