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| 1 | MicroRNAs:a new ray of hope for diabetes mellitus显示文摘Diabetes mellitus has become one of the most common chronic diseases,thereby posing a major challenge to global health.Characterized by high levels of blood glucose(hyperglycemia),diabetes usually results from a loss of insulin-producing β-cells in the pancreas,leading to a deficiency of insulin(type 1 diabetes),or loss of insulin sensitivity(type 2 diabetes).Both types of diabetes have serious secondary complications,such as microvascular abnormalities,cardiovascular dysfunction,and kidney failure.Various complex factors,such as genetic and environmental factors,are associated with the pathophysiology of diabetes.Over the past two decades,the role of small,single-stranded noncoding microRNAs in various metabolic disorders,especially diabetes mellitus and its complications,has gained widespread attention in the scientific community.Discovered first as an endogenous regulator of development in the nematode Caenorhabditis elegans,these small RNAs post-transcriptionally suppress mRNA target expression.In this review,we discuss the potential roles of different microRNAs in diabetes and diabetes-related complications. | Munish Kumar Sayantan Nath Himanshu K Prasad G D Sharma Yong Li | 2012 | Protein & Cell2012，3，10： | 14 |
| 2 | Microstructure,mechanical response and fractography of AZ91E/Al_(2)O_(3)_(p) nano composite fabricated by semi solid stir casting method显示文摘The present study confers to the fabrication and its characterization of magnesium alloy(AZ91E)based nano composites with nano Al_(2)O_(3) particulate reinforcements.A novel Semi Solid stir casting technique was adopted for the fabrication of the composite.An average particle size of 50 nm was used as reinforcement to disperse in matrix.The effects of change in weight fraction of reinforcements on the distribution of particles,particle–matrix interfacial reactions,physical as well as mechanical properties were reported.The SEM and EDS analysis has shown the uniform distribution of particles in the composite along with the presence of elements.The mechanical properties of reinforced and unreinforced composite were evaluated and presented.Fractography of tensile specimens was also discussed. | Sameer Kumar D Suman K.N.S Tara Sasanka C Ravindra K Palash Poddar | 2017 | Journal of Magnesium and Alloys2017，5，1： | 4 |
| 3 | Evaluating the effectiveness of marine actinobacterial extract and its mediated titanium dioxide nanoparticles in the degradation of azo dyes显示文摘Aim of the present study was to synthesize titanium dioxide nanoparticles(TiO2 NPs) from marine actinobacteria and to develop an eco-friendly azo-dye degradation method. A total of five actinobacterial isolates were isolated from Chennai marine sediments, Tamilnadu, India and analyzed for the synthesis of TiO2 NPs using titanium hydroxide. Among these, the isolate PSV 3 showed positive results for the synthesis of TiO2 NPs, which was confirmed by UV analysis. Further characterization of the synthesized TiO2 NPs was done using XRD, AFM and FT-IR analysis. Actinobacterial crude extract and synthesized TiO2 NPs was found efficient in degrading azo dye such as Acid Red 79(AR-79) and Acid Red 80(AR-80). Degradation percentage was found to be 81% for AR-79, 83% for AR-80 using actinobacterial crude extract and 84% for AR-79, 85% for AR-80 using TiO2 NPs. Immobilized actinobacterial cells showed 88% for AR-79 and 81% for AR-80, dye degrading capacity. Degraded components were characterized by FT-IR and GC-MS analysis. The phytotoxicity test with 500 μg/mL of untreated dye showed remarkable phenotypic as well as cellular damage to Tagetes erecta plant. Comparatively no such damage was observed on plants by degraded dye components. In biotoxicity assay, treated dyes showed less toxic effect as compared to the untreated dyes. | S Priyaragini S Veena D Swetha L Karthik G Kumar K V Bhaskara Rao | 2014 | Journal of Environmental Sciences2014，26，4： | 4 |
| 4 | The effects of silicon on the properties of tantalum 显示文摘 | Mose K D Chatterjee T K Kumar P | 1989 | J Met1989，41，10： | 1 |
| 5 | Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock显示文摘 | Kumar A Roberts D Wood K E | 2006 | Crit Care Med2006，34，6： | 1 |
| 6 | Efficient and simple colorimetric fluoride ion sensor based on receptors having urea and thiourea binding sites显示文摘 | Jose A D Kumar K D Ganguly B | 2004 | Org Lett2004，6，20： | 1 |
| 7 | Timing, quantification and tectonic modelling of Pliocene-Quartenary movements in the NW Himalaya:evidence from fission track dating显示文摘 | Kumar D Singh S | 2000 | Earth and Planetary Science Letters2000，179，43： | 1 |
| 8 | Experimental and finite element modeling studies on single-layer and multi-layer 1-3 piezocomposite transducers显示文摘 | RAMESH R PRASAD C D VINOD KUMAR T K | 2006 | Ultrasonics2006，44，2006： | 1 |
| 9 | MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods 显示文摘 | Tamura K Peterson D Peterson N Stecher G Nei M Kumar S | 2011 | Molecular Biology and Evolution2011，28，10： | 1 |
| 10 | Finite-time attitude tracking control for spacecraft using terminal sliding model and chebyshev neural network显示文摘 | ZOU A KUMAR K D HOU Z | | 0，，： | 1 |
| 11 | Target- ed abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer 显示文摘 | Shrimali D Shanmugam M K Kumar A P | 2013 | Cancer Letters2013，341，2： | 1 |
| 12 | MEGA5 : Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods 显示文摘 | Tamura K Peterson D Peterson N Stecher G Nei M Kumar S | 2011 | Molecular Biology and Evolution2011，28，： | 1 |
| 13 | Instructional adapta- tion in the management of escape-maintained behavior in a classroom 显示文摘 | Moore D W Anderson A Kumar K | 2005 | Journal of Positive Behavior Interventions2005，，4： | 1 |
| 14 | High diversity andwidespread occurrence of mitotic spore mats in ectomycorrhizalPezizales显示文摘 | Healy R A Smith M E Bonito G M Pfister D H Ge Z W Guevara G G ’ Williams G Stafford K Kumar L Lee T HobartC Trappe J Vilgalys R McLaughlin D J | 2013 | Molecular Ecology2013，22，： | 1 |
| 15 | Performance of Kenics static mixer over a wide range of Reynolds number 显示文摘 | Kumar V Vaibhav Shirke Nigam K D P | 2008 | Chem Eng J2008，139，2： | 1 |
| 16 | Review of dynamics and control of non-electrodynamic tethered satellite systems 显示文摘 | KUMAR K D | 2006 | Journal of Spacecraft and Rockets2006，43，4： | 1 |
| 17 | Characterization of tensile properties of tailor welded IF steel sheets and their formability in stretch forming显示文摘 | PANDA S K KUMAR D R KUMAR H | 2007 | Journal of Materials Processing Technology2007，183，： | 1 |
| 18 | MEGA5: molecular evolutionary genetics analysis using maximumlikelihood, evolutionary distance, and maximum parsimony methods显示文摘 | Tamura K Peterson D Peterson N Stecher G Nei M Kumar S | 2011 | Mol Biol Evol2011，28，： | 1 |
| 19 | Review on dynamics and control of nonelectrodynamic tethered satellite systems 显示文摘 | KUMAR K D | 2006 | J Spacecraft & Rockets2006，43，4： | 1 |
| 20 | Effect of welding pa- rameters on mlcrostructure and mechanical properties of friction stir welded joints of AA7039 aluminum alloy显示文摘 | SHARMA C DWIVEDI D K KUMAR P | 2012 | Materials and Design2012，36，： | 1 |
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