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498篇 您的检索式:作者名="Kopple"
    题名 作者 年代 出处 被引量
1胰岛素样生长因子1对慢性肾功能衰竭大鼠骨骼肌蛋白质代谢的影响显示文摘目的 探讨胰岛素样生长因子1(IGF-1)在慢性肾功能衰竭(CRF)大鼠骨骼肌蛋白质代谢上的作用。方法 用放射免疫分析法测定CRF大鼠和配对喂养的假手术(SO)对照大鼠血清及骨骼肌中IGF-1的含量;计算骨骼肌蛋白质的基础合成率及分解率;评估重组人胰岛素样生长因子-1(rhIGF-1)对骨骼肌蛋白质合成与分解的影响。结果(1)CRF组血清和骨骼肌中IGF-1含量明显低于SO组;(2)CRF组骨骼肌基础蛋白合成率显著低于SO组,基础蛋白分解率显著高于SO组;(3)rhIGF-1对CRF大鼠骨骼肌蛋白质合成的促进作用仅为SO大鼠的25%-44%,对其分解的抑制作用仅为SO大鼠的15%-42%。结论CRF时,血清及骨骼肌的IGF-1含量的减少和骨骼肌对IGF-1促进蛋白质合成代谢作用的抵抗可能是白质合成减少、分解增强,导致营养不良、肌肉萎缩的主要原因。高秀林 Ding Hu Joel D. Kopple 2000中华肾脏病杂志2000,16,6:3
2Risks of chro- nic metabolic acidosis in patients with chronic kidney disease 显示文摘Kopple J D Kalantar-Zadeh K Mehrotra R 2005Kidney Int: Suppl2005,,:1
3The rationale for the use of growth hormone of ins ulin-like grow factor 1 in adult patients with renal failure显示文摘Kopple JD 1992Miner Electro l Metab1992,18,:1
4National kidney foundation K/DOQI clinical practice guidelines for nutrition in chronic renal failure显示文摘Kopple JD 2001Am J Kidney Dis2001,37,2:1
5A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease显示文摘Fouque D Kalantar-Zadeh K Kopple J 2008Kidney Int2008,73,:1
6Some Explanatory Discourse on Metadiscourse显示文摘Vande Kopple College Composition and0,,5:1
7A Malnutrition-Inflammation score is correlated with morbidity and Mortality in Maintenance Hemodialysis patients显示文摘Kamyar KZ Joel D Kopple MD 2001American Journal of Kidney Disease2001,38,6:1
8Causes and prevention of protein-energy wast- ing in chronic kidney failure 显示文摘Dukkipati R Kopple JD 2009Semin Nephrol2009,29,1:1
9Nutritional assessment of continous ambulatory peritoneal dialysis patients:an international study显示文摘Young GA Kopple JD Lindholm B 1991Am J Kidney Dis1991,17,4:1
10Some Exploratory Discourse on Metadiscourse显示文摘Vande Kopple W 1985College Composition and Communication1985,,36:1
11Effect of diabetes mellitus on protein-energy wasting and protein wasting in end-stage renal disease显示文摘Noori N Kopple JD 2010Semin Di- al2010,23,2:1
12A malnutrition-inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients显示文摘KALANTAR ZADEH K KOPPLE J D BLOCK G 2001Am J Kidney Dis2001,38,6:1
13The synthesis of poly-α-amino acids in anhydrous hydrogen fluoride显示文摘Kenneth D Kopple Joseph J Kate 1956J Am Chem Soc1956,78,:1
14Body weight - for - height rela- tionships predict mortalizty in maintenance hemodialysis patients 显示文摘Kopple JD Zhu X Lew NL 1999Kidney Int1999,56,3:1
15A proposed nomenclature and diagnostic criteria for protein-ener- gy wasting in acute and chmni, kidn6y disease显示文摘Fouque D Kalantar-zadeh K Kopple J 2008Kid- ny Int2008,73,4:1
16Relative contributions of nutrition and inflammation to clinical outcome in dialysis patients显示文摘Kalantar-Zadeh K Kopple JD 2001Am J Kidney Dis2001,38,13:1
17A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease 显示文摘Fouqne D Kalantar-Zadeh K Kopple J 2008Kidney Int2008,73,4:1
18Nutritional assess ment of continuous ambulatory peritoneal dialysis patients:an international study显示文摘Young GA Kopple JD Lindholm B 1991Am J Kidney Dis1991,17,:1
19National kidney foundation K/DOQI clinical practice guidelines for nutrition in chronic renal failure显示文摘Kopple JD 2001Am 3 Kidney Dis2001,37,:1
20Energy requirement in chronic renaL fail- ure and hemodialysis patients显示文摘Monteon FJ Kopple JD 1984Abstracts of IX th International Congress of Nephrology1984,316,:1
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