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| 1 | Effects of resveratrol and methylprednisolone on biochemical,neurobehavioral and histopathological recovery after experimental spinal cord injury显示文摘瞄准:在损害(SCI ) 在老鼠建模的试验性的脊髓调查 resveratrol 的 neuroprotective 效果。方法:男 Wistar 白鼠称 200-250 g 被使随机化进六个组。重量落下损伤为 SCI 被执行。组 1 独自经历了椎板切除术。组 2 经历了 SCI 跟随的椎板切除术。3, 4, 5,和 6 经历了的组 SCI 跟随并且收到了 resveratrol (100 mg/kg ) 的椎板切除术,甲基氢化尼松(MP )(30 mg/kg ) ,加 MP (30 mg/kg ) 的 resveratrol (100 mg/kg ) ,和乙醇(2%) 分别地。老鼠为生物化学的分析被划分成二亚群(在外科以后在 24 点杀死了 h ) 并且为 neurobehavioral 和组织病理学说的评估(在外科以后在 6 点杀死了星期) 。在外科以后的 Posttraumatic 神经病学的恢复每周被记录。结果:3 和 5 揭示了的组显著地比组织 4 降低 malon-dialdehyde,氮的氧化物,黄嘌呤氧化酶,和更高的谷胱甘肽层次(P<0.05 ) 。神经病学的恢复率显著地更好在比组织 4 组织 3 和 5 (P<0.05 ) 。当针的损伤尺寸比率被比较时,在治疗组之间没有有效差量。结论:Resveratrol 处理比 MP 处理在损伤的尖锐阶段揭示了更好生物化学的恢复。尽管 resveratrol 和联合处理比 MP 处理揭示了更好的 neurobehavioral 恢复;resveratrol, MP,和联合处理形式在实验的最后的阶段在一样的水平改进了组织病理学说的恢复。当每药有行动的不同抗氧化的机制,与 MP 包含 resveratrol 和不同剂量联合的不同剂量的未来研究能答应更好的结果。 | Ozkan ARIES Suleyman CAYLI Eyup ALTINOZ Iclal GURSES Neslihan YUCEL Ayhan KOCAK Saim YOLOGLU Yusuf TURKOZ | 2006 | Acta Pharmacologica Sinica2006，27，10： | 18 |
| 2 | Endovascular treatment of carotid cavernous sinus fistula: A systematic review显示文摘Carotid cavernous sinus fistulas are abnormal communications between the carotid system and the cavernous sinus. Several classification schemes have described carotid cavernous sinus fistulas according to etiology, hemodynamic features, or the angiographic arterial architecture. Increased pressure within the cavernous sinus appears to be the main factor in pathophysiology. The clinical features are related to size, exact location, and duration of the fistula, adequacy and route of venous drainage and the presence of arterial/venous collaterals. Noninvasive imaging (computed tomography, magnetic resonance, computed tomography angiography, magnetic resonance angiography, Doppler) is often used in the initial workup of a possible carotid cavernous sinus fistulas. Cerebral angiography is the gold standard for the definitive diagnosis, classification, and planning of treatment for these lesions. The endovascular approach has evolved as the mainstay therapy for definitive treatment in situations including clinical emergencies. Conservative treatment, surgery and radiosurgery constitute other management options for these lesions. | Bora Korkmazer Burak Kocak Ercan Tureci Civan Islak Naci Kocer Osman Kizilkilics | 2013 | World Journal of Radiology2013，5，4： | 14 |
| 3 | Endovascular treatment of extracranial vertebral artery stenosis显示文摘Percutaneous angioplasty and stenting for the treatment of extracranial vertebral artery(VA) stenosis seems a safe,effective and useful technique for resolving symptoms and improving blood flow to the posterior circulation,with a low complication rate and good long-term results.In patients with severe tortuosity of the vessel,stent placement is a real challenge.The new coronary balloon-expandable stents may be preferred.A large variability of restenosis rates has been reported.Drug-eluting stents may be the solution.After a comprehensive review of the literature,it can be concluded that percutaneous angioplasty and stenting of extracranial VA stenosis is technically feasible,but there is insufficient evidence from randomized trials to demonstrate that endovascular management is superior to best medical management. | Burak Kocak Bora Korkmazer Civan Islak Naci Kocer Osman Kizilkilic | 2012 | World Journal of Radiology2012，4，9： | 13 |
| 4 | Ischemic stroke due to carbon monoxide intoxication: Two case reports显示文摘Dear editor,Following its entrance into the human body through inhalation,carbon monoxide(CO)forms carboxyhemoglobin(COHb)by binding to hemoglobin(Hb)within the blood.Massive ischemic tissue necrosis occurs in 0.5%–1% of cases with CO poisoning.^([1])The affinity of CO to Hb is 200–250 times more | Atif Bayramoglu Abdullah Osman Kocak Esra Kadioglu | 2018 | World Journal of Emergency Medicine2018，9，1： | 11 |
| 5 | TiAl/IN718合金过渡液相连接显示文摘采用过渡液相TLP(TransientLiquidPhase)连接技术 ,以金属Ti,Cu ,Ni箔构成复合焊料连接TiAl和IN71 8合金 .研究了保温时间对接头界面结构的影响 .实验结果表明 :采用Ti Cu ,Ti Ni复合焊料可以制备无缺陷的接头 ,但 2种焊料形成液相的过程和机理不同 .由于在等温凝固过程中 ,从IN71 8合金中扩散过来的合金元素可在焊缝区聚集 ,从而在接头中形成亚层结构 .通过对接头焊缝区的组织分析和硬度测试表明 ,在实验条件下Ti Ni焊料的等温凝固过程持续时间比Ti | 段辉平 罗俊 张涛 Mustafa Kocak | 2004 | 北京航空航天大学学报2004，30，10： | 8 |
| 6 | Evaluation of systemic risk factors in different optical coherence tomographic patterns of diabetic macular edema显示文摘● AIM: To elucidate the relationship between systemic risk factors and different patterns of diabetic macular edema(DME) determined with optical coherence tomography(OCT).● METHODS: In this cross-sectional study, DME was classified by OCT as diffuse retinal thickness(DRT), cystoid macular edema(CME) and serous retinal detachment(SRD) and the relationship between the systemic risk factors and DME patterns was evaluated.● RESULTS: Of the 57 patients with DME, 21(36.8%) had DRT, 24(42.1%) had CME and 12(21.0%) had SRD. Microor macro-albuminuria was significantly higher in the DRT pattern(61.9%) compared with the SRD(50.0%) and CME patterns(25.0%; P=0.040). Hemoglobin A1 c(Hb A1 c) level was significantly higher and patients were younger in the DRT pattern group(P=0.034, P=0.032). Best corrected visual acuity was the worst and central macular thickness was the thickest in the CME pattern group.● CONCLUSION: Micro-or macro-albuminuria may be more frequent and Hb A1 c level may be higher in patients with DRT. These patients are also seen to be younger than patients with non-DRT. | Durgul Acan Eyyup Karahan Nilufer Kocak Suleyman Kaynak | 2018 | International Journal of Ophthalmology(English edition)2018，11，7： | 5 |
| 7 | Comparison of Densiron 68 and 1 000 cSt silicone oil in the management of rhegmatogenous retinal detachment with inferior breaks显示文摘AIM:To compare success rates and complications of Densiron 68 and 1000cSt silicone oil (SO) in the management of rhegmatogenous retinal detachment (RRD) with inferior breaks (IBs). METHODS:Totally 61 eyes of 61 consecutive patients with RRD with IBs were assigned to pars plana vitrectomy (PPV) with Densiron (n =31) or PPV with SO (n=30) in order of presentation. SO and Densiron removal was performed 3 months after initial surgery. Follow up visits were terminated 6 months after SO removal. ·RESULTS:With a single operation, the Densiron group showed 84% and SO 74% reattachment. With further surgery, both groups showed 90% reattachment. Complications such as cataract, raised intraocular pressure (IOP), inflammatory reaction, macular epiretinal membranes, and emulsification of SO were seen in both groups. CONCLUSION:Densiron and SO are found to have similar success rates and complications. | Ibrahim Kocak Haci Koc | 2013 | International Journal of Ophthalmology(English edition)2013，6，1： | 4 |
| 8 | Short-term effects of intravitreal triamcinolone acetonide injection on ocular blood flow evaluated with color Doppler ultrasonography显示文摘AIM:To evaluate the changes in ocular blood flow with color Doppler ultrasonography(CDU) after intravitreal triamcinolone acetonide(IVTA) injection.METHODS:A total of 46 patients who underwent IVTA(4 mg/0.1 mL) injection for diabetic macular edema(DME)(n =22), central retinal vein occlusion(CRVO)(n =12) and choroidal neovascular membrane(CNVM)(n =12) were included in the study. Peak systolic velocity(PSV), end diastolic velocity(EDV) and resistivity index(RI) were measured from the ophthalmic artery(OA), the central retinal artery(CRA) and the posterior ciliary artery(PCA)of each patient with CDU before, at the end of the first week and at the end of the first month following IVTA injection.RESULTS:In the DME group, PSV of OA at the first of the first month(mean ±SD)(37.48 ±10.87 cm/s) increased compared to pre-injection value(31.39 ±10.84 cm/s)(P =0.048). There was a statistically significant decrease(P =0.049) in PSV of CRA at the end of the first month(7.97±2.67 cm/s) compared to the pre-injection(9.47±3.37 cm/s).There was not any statistically significant difference onthe other parameters in the DME group. Also, there was not any statistically significant difference on the ocular blood flow values in the CRVO and CNVM groups.CONCLUSION:We observed that 4 mg/0.1 mL IVTA increased PSV of OA and decreased PSV of CRA in DME patients and did not have any effect on ocular blood flow values of CRVO and CNVM patients. | Mustafa Alpaslan Anayol Yasin Toklu Elif Asik Kamberoglu Sabri Raza Hasan Basri Arifoglu Huseyin Simavli Ayse Gul Kocak Altintas Saban Simsek | 2014 | International Journal of Ophthalmology(English edition)2014，7，5： | 4 |
| 9 | 比较标准超声波测量仪和新型光学生物测量仪计算人工晶状体屈光度的准确性(英文)显示文摘目的:比较超乳手术时应用新型光学生物测量仪和标准超声波测量仪计算人工晶状体的屈光度及屈光结果。方法:前瞻性研究。研究包含37例37眼白内障患者接受白内障超声乳化联合人工晶状体植入术。同一测量人员分别使用新型光学生物测量仪(Aladdin)与标准超声波测量仪(Sonomed AB 5500)对白内障患者进行检测。通过这两种设备记录生物测定参数,包括眼轴长度、角膜曲率、前房深度及人工晶状体屈光度数。分析术后实际屈光不正与两台设备根据SRK/T公式计算的误差,比较两台设备检查结果的平均估计误差(EE)、平均绝对估计误差(AEE)及生物测定参数。结果:Aladdin测量仪(23.45±0.73 mm)较超声波测量仪(23.2±0.75 mm)检测出的眼轴显著较长(P=0.01)。Aladdin测量仪的EE与AEE均明显小于超声波测量仪(P=0.0006与0.03)。应用Aladdin测量的大多数眼与目标屈光度相差在±0.5(67%)及±1.00(97%)以内。结论:Aladdin光学生物测量仪较超声波测量仪更精确,屈光结果更准确。 | Faruk Kaya Ibrahim Kocak Ali Aydin Hakan Baybora Koray Karadayi | 2016 | 国际眼科杂志2016，16，5： | 3 |
| 10 | Effectivity of intraoperative adjustable suture technique in horizontal strabismus显示文摘AIM:To compare the long-term effectivity of intraoperative adjustable suture technique with traditional non-adjustable strabismus surgery.·METHODS:Two hundred and thirty-three patients,who underwent strabismus surgery either with traditional procedures or one-stage intraoperative adjustable suture technique,were included in our long-term follow-up study.One hundred and eighteen patients were evaluated in traditional surgery group(TSG) and 115 who underwent adjustable suture were in the one-stage intraoperative adjustable surgery group(ASG).In this group 9 patients had paralytic strabismus and 16 had reoperations,2 patients had restrictive strabismus related to thyroid eye disease.The mean follow up in the TSG was 26.2 months and it was 24.8 months in the ASG group.·RESULTS:In patients with exotropia(XT) the mean correction of deviation for near fixation in ASG(32.4 ±13.2PD) and in TSG(26.4±8.2PD) were similar(P =0.112).The correction for distant fixation in ASG(33.2±11.4PD)and TSG(30.9±7.2PD) were not significantly different(P =0.321).In patients with esotropia(ET) even the mean correction of deviation for both near(31 ±12PD) and distant(30.6±12.8PD) fixations were higher in ASG thanin TSG,for both near(28.27±14.2PD) and distant(28.9±12.9PD) fixations,the differences were not significant(P =0.346,0.824 respectively).The overall success rate of XT patient was 78.9% in TSG and 78.78% in ASG,the difference was not significant(P =0.629).The success rates were 78.75% in TSG and 75.51% in ASG in ET patient,which was also not significantly different(P =0.821).·CONCLUSION:Although patients in ASG had more complex deviation such as paralysis,reoperations and restrictive strabismus,success rates of this tecnique was as high as TSG which did not contain complicated deviation.One-stage intraoperative adjustable suture technique is a safe and effective method for cooperative patient who has complex deviation. | Ayse Gul Kocak Altintas Hasan Basri Arifoglu Inci Kocak Midillioglu Elif Damar Gungor Saban Simsek | 2013 | International Journal of Ophthalmology(English edition)2013，6，4： | 3 |
| 11 | 初级运动皮质:健康志愿者被动成像的fMRI效用的初步结果显示文摘目的采用BOLD—fMRI评价肢体主动和被动运动时初级运动皮质激活的一致性。方法本研究得到了当地伦理委员会的批准,所有参加本研究的志愿者均签署知情同意书。在11名健康志愿者(4名女性,7名男性,年龄范围24~42岁)手、肘、肩、踝、膝及髋进行主动和被动运动过程中进行fMRI检查。采集的数据叠加到三维解剖影像上。采用交叉相关分析,阈值在0.4水平(P〈0.01)的基础上分析激活的容积。根据解剖学标准,感兴趣区放置在中央前后回。 | M. Kocak J.L. Ulmer M. Sahin Ugurel W. Gaggl R. W. Prost 夏爽(译) 祁吉(校) | 2009 | 国际医学放射学杂志2009，32，4： | 3 |
| 12 | Progress in joining of advanced materials显示文摘 | Cam G Kocak M | 1998 | International Materials Reviews1998，43，1： | 2 |
| 13 | Relation of eye dominancy with color vision discrimination performance ability in normal subjects显示文摘AIM:To evaluate the performance of dominant eye(DE) for color vision discrimination ability among the medical students with normal color vision.METHODS:Total of 50 students studying at Baskent University Faculty of Medicine,including 31 males(62%) and 19 females(38%),with visual acuity of 20/20 and without congenital color vision deficiency(CCVD) evaluated by Ishihara pseudoisochromatic plate test(IPPT) were recruited for this prospective comparative study upon their voluntary participation.DE was determined by the Gündogan Method.The color discrimination ability was examined with the FarnsworthMunsell 100 hue(FM100) test.Test was applied by two days interval to all subjects for the three times while two eyes(TE),right eye(RE) and left eye(LE) were seeing for detecting red-green(r/g),blue-yellow(b/y) local color spectral regions error scores.The error scores were evaluated for both in DE and non-dominant(NDE).P values below 0.05 were considered to be statistically significant.RESULTS:The students aged 21.18±2.52 years(mean±SD).Without sex difference the RE and the LE dominancy were found 22(44%) and 28(56%) respectively and FM 100 test total error scores of DE in both r/g-b/y regions were found without gender difference 24.12±14.70,34.68±18.95,respectively.For the NDE in both,r/gb/y regions error scores without gender difference were 32.20±19.21,36.24±17.56,respectively.The difference of total error scores between the DE and NDE was found as 58.80±29.92,68.44±31.46.The statistical differences among the DE and the NDE in r/g local region and total error scores were found significant in both genders(P<0.05,P<0.001). CONCLUSION:The color vision discrimination performance ability was found prominent for DE.This superiority was attributed to higher sensitivity of the r/g local color spectral region.We conclude that DE has priority in r/g color spectral region,probably including inhibition of NDE. | Belkis Koctekin Nimet ünay Gündogan Ays Gül Kocak Altintas Ayse Canan Yazici | 2013 | International Journal of Ophthalmology(English edition)2013，6，5： | 2 |
| 14 | 角膜厚度对三种不同眼压计测量的影响(英文)显示文摘目的:比较采用Goldmann压平眼压计(Goldmann applanation tonometer,GAT)、非接触眼压计(non-contact tonometer,NCT)和Schiotz眼压计(Schiotz tonometer,ST)的眼压(intraoeular pressure,IOP)测量,评估角膜中央厚度(central corneal thickness,CCT)对读数的影响。方法:使用GAT、NCT和ST对所有患者的右眼进行眼压测量。超声角膜厚度测量法测定CCT。所有IOP及CCT测量由同一检查者进行。计算CCT25%(Q1)百分位数和75%(Q3)百分位数值,并通过这种方法将该组分为薄、中、厚角膜亚组。使用Statplus软件进行统计分析。结果:全系列144眼,GAT测量平均IOP为17.4±4.9mmHg,NCT为16.0±5.8mmHg,ST为14.0±4.0mmHg(Friedman方差分析P<0.01)。IOP水平和CCT之间的相关系数NCT为0.787(P<0.01),GAT为0.630(P<0.01),ST为0.565(P<0.01)。ST测量中,纠正的IOP误差和CCT之间的相关性在厚角膜明显弱(r=0.381,P=0.022)。结论:NCT是最易受不同CCT影响的设备。ST读数似乎比GAT和NCT读数受CCT的影响小。特别是在厚角膜,与NCT和GAT相比,ST可以被认为是一个更可靠的仪器。 | Ibrahim Kocak Faruk Kaya | 2012 | 国际眼科杂志2012，12，1： | 2 |
| 15 | Evaluation of bacterial contamination rate of the anterior chamber during phacoemulsification surgery using an automated microbial detection system显示文摘·AIM: To assess the incidence of anterior chamber bacterial contamination during phacoemulsification surgery using an automated microbial detection system(BacT/Alert).·METHODS: Sixty-nine eyes of 60 patients who had uneventful phacoemulsification surgery, enrolled in this prospective study. No prophylactic topical or systemic antibiotics were used before surgery. After antisepsis with povidone-iodine, two intraoperative anterior chamber aqueous samples were obtained, the first whilst entering anterior chamber, and the second at the end of surgery. BacT/Alert culture system was used to detect bacterial contamination in the aqueous samples.·RESULTS: Neither aqueous samples obtained at the beginning nor conclusion of the surgery was positive for microorganisms on BacT/Alert culture system. The rate of bacterial contamination during surgery was 0%. None of the eyes developed acute-onset endophthalmitis after surgery.· CONCLUSION: In this study, no bacterial contamination of anterior chamber was observed during cataract surgery. This result shows that meticulous surgical preparation and technique can prevent anterior chamber contamination during phacoemulsification cataract surgery. | Ibrahim Kocak Funda Kocak Bahri Teker Ali Aydin Faruk Kaya Hakan Baybora | 2014 | International Journal of Ophthalmology(English edition)2014，7，4： | 2 |
| 16 | 白内障超声乳化术后前房膜形成的危险因素(英文)显示文摘目的:探讨白内障超声乳化术后前房膜形成的危险因素。方法:对1356例行白内障超声乳化+单片式PMMA人工晶体植入术患者进行前瞻性研究。假性囊膜剥脱综合症,核硬度,瞳孔大小,超声时间,实际超声时间,系统性疾病,术中并发症(囊膜撕裂,悬韧带断裂,后囊破裂伴玻璃体丢失),IOL植入位置和术后并发症(眼内压变化,粘连形成)作为膜形成的危险因素分析。结果:观察到111例患者(8.1%)术后出现伴有膜形成的纤维素性前葡萄膜炎。膜形成平均时间是术后第2d(术后第1~7d),膜存在持续时间平均为5.2d(1~48d)。在膜形成病例中,+4级核病例占45%,而在无膜形成病例中仅为13.5%,差异具有显著统计学意义(P<0.05)。在膜形成组,平均超声时间为2.4min,平均实际超声时间为32.8s,而无膜形成组分别为1.8min和22.1s。这两项参数在膜形成组均明显较长(P<0.05)。在膜形成组中,出现后囊破裂伴玻璃体丢失和IOL睫状沟植入者占33%,而无膜形成组为11%(P<0.05)。其他危险因素在膜形成组和无膜形成组中的比较无统计学意义。在术后第1d和第7d,平均最佳矫正视力(Snellen视力表)在膜形成组分别为0.2和0.4,无膜形成组为0.4和0.6(P<0.05)。但术后3mo,平均最佳矫正视力在膜形成组和无膜形成组中结果相似(分别为0.8和0.9)。结论:晶状体核硬度较高,较长超声时间和实际超声时间,术中后囊破裂是术后前房纤维膜形成的明显相关性危险因素。 | Ayse Gul Kocak Altintas M. Alpaslan Anayol Saban Simsek | 2006 | 国际眼科杂志2006，6，6： | 2 |
| 17 | 一种新的计算机适应色觉试验(英文)显示文摘目的:提出一种新的计算机适应色觉试验(NCACVT)并且解释它在实际应用中的可靠性和重要性。方法:法-孟二式100色度试验(FM100HT)和Holmgren试验已经被改良并且适应计算机应用。经典的Ishihara假同色法试验方法(IPPT)已被假定是色盲的一个简便的筛选检查工具;因此依照Ishihara试验结果,受试者被分为色觉有缺陷组(第1组)和对照组(第2组)。第1组为色觉有缺陷者13例(男12例,女1例),年龄在19~29(平均21)岁,而第2组为对照组,13个受试者色觉无缺陷(男8例,女5例),年龄在19~28(平均22)岁。为了研究两组人的色觉敏感性,所有的受试者都要进行FM100HT和NCACVT试验。将经典的IPPT,FM100HT和NCACVT的试验结果用统计学方法进行比较。在这两组中NCACVT和FM100HT的误差计分用秩和检验来分析。结果:在误差计分中的差别分别在统计学上是有显著意义的(U=169,P<0.05;U=153P<0.05)。根据NCACVT来诊断色觉缺陷的临界点是通过使用接受机器作特征曲线(ROC)而被发现是23。根据23这个临界点的误差计分,在筛选检查色觉缺陷方面,发现NCACVT具有100%的敏感性和100%的特异性。结论:根据Harper和Reeves,这些特点使得这个试验成为一个可靠的、有创意的眼科实践筛选试验。 | Nimet ünay Gündogan Nezih Durmazlar Aysegül Kocak Altintas Koray Gümüs | 2007 | 国际眼科杂志2007，7，2： | 2 |
| 18 | Protective effect of melatonin on experimental spinal cord ischemia 显示文摘 | Erten SF Kocak A Ozdemir I | 2003 | Spinal Cord2003，41，10： | 1 |
| 19 | Effects of streptozotocin - induced diabetes and pentylenetetrazol - induced seizure on brain cortex ( Ca^2+ ) ATPase activity in rats显示文摘 | Oner P Kocak H Oztas B | 2000 | Int J Neurosci2000，103，14： | 1 |
| 20 | Smart grid technologies: communication technologies and standards显示文摘 | Giingtir V C Sahin D Kocak T | 2011 | IEEE Transactions on Industrial Informatics2011，7，4： | 1 |
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