|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Cardiovascular magnetic resonance imaging assessment of outcomes in acute myocardial infarction显示文摘Cardiovascular magnetic resonance(CMR) imaging uniquely characterizes myocardial and microvascular injury in acute myocardial infarction(AMI), providing powerful surrogate markers of outcomes. The last 10 years have seen an exponential increase in AMI studies utilizing CMR based endpoints. This article provides a contemporary, comprehensive review of the powerful role of CMR imaging in the assessment of outcomes in AMI. The theory, assessment techniques, chronology, importance in predicting left ventricular function and remodelling, and prognostic value of each CMR surrogate marker is described in detail. Major studies illustrating the importance of the markers are summarized, providing an up to date review of the literature base in CMR imaging in AMI. | Jamal N Khan Gerry P McCann | 2017 | World Journal of Cardiology2017，9，2： | 16 |
| 2 | Prospective validation of %p2PSA and the Prostate Health Index, in prostate cancer detection in initial prostate biopsies of Asian men, with total PSA 4-10 ng ml-1显示文摘尽管有它为屏蔽的前列腺癌症的普遍使用,低特性使 PSA 成为非最优的 biomarker,特别在 4-10 ng ml 1 的诊断灰色的地区。假积极与伴随的病态导致不必要的活体检视。这在与在 4.0 和 10 ng ml 1 之间的全部的 PSA 介绍的亚洲人是 % p2PSA 和前列腺健康索引(PHI ) 的第一未来的确认研究。我们学习了在 50 和 75 岁之间的 157 个亚洲人,与每直肠的前列腺考试的正常,经历他们的第一前列腺活体检视,用一个标准化活体检视协议,为 4-10 ng ml 1 的 PSA 层次。(19.1%) 三十被发现在活体检视上有前列腺癌症。有或没有前列腺癌症的病人之间的统计上重要的差别被作出对有利的裁决全部的 PSA, p2PSA, % p2PSA,和 PHI。在为全部的 PSA, % fPSA, % p2PSA,和 PHI 操作典型曲线的接收装置的曲线下面的区域分别地是 0.479, 0.420, 0.695,和 0.794。PHI 最好预言 prostatic 活体检视结果。在 90% 的敏感, PHI 的特性(95% CI ) 是 58.3% ,多于在 17.3% 点使全部的 PSA 的特性增加两倍,潜在地避免 77 (49%) 不必要的活体检视。类似于研究在主要白种人人口,我们有希望地证明了 % p2PSA 和 PHI 极大地超过总数并且释放总计 PSA 比率,在前列腺癌症的察觉起初活体检视。更高的 PHI 层次也对应于增加检测 GS 7 癌症的风险。我们验证了 PHI 的使用与在 4 和 10 ng ml 1 之间的浆液 PSA 在亚洲人关于前列腺活体检视帮助决策。 | Lincoln GL Tan Yung Khan Tan Bee Choo Tai Karen ML Tan Vineet Gauhar Ho Yee Tiong Robert CW Hawkins Thomas P Thamboo Felicia SK Hong Edmund Chiong | 2017 | Asian Journal of Andrology2017，19，3： | 13 |
| 3 | Effects of the nitrification inhibitor nitrapyrin and the plant growth regulator gibberellic acid on yield-scale nitrous oxide emission in maize fields under hot climatic conditions显示文摘Nitrification inhibitors are widely used in agriculture to mitigate nitrous oxide(N_(2)O)emission and increase crop yield.However,no concrete information on their mitigation of N_(2)O emission is available under soil and environmental conditions as in Pakistan.A field experiment was established using a silt clay loam soil from Peshawar,Pakistan,to study the effect of urea applied in combination with a nitrification inhibitor,nitrapyrin(2-chloro-6-tri-chloromethyl pyridine),and/or a plant growth regulator,gibberellic acid(GA_3),on N_(2)O emission and the nitrogen(N)uptake efficiency of maize.The experimental design was a randomized complete block with five treatments in four replicates:control with no N(CK),urea(200 kg N ha^(-1))alone,urea in combination with nitrapyrin(700 g ha^(-1)),urea in combination with GA_3(60 g ha^(-1)),and urea in combination with nitrapyrin and GA_3.The N_(2)O emission,yield,N response efficiency,and total N uptake were measured during the experimental period.The treatment with urea and nitrapyrin reduced total N_(2)O emission by 39%–43%and decreased yield-scaled N_(2)O emission by 47%–52%,relative to the treatment with urea alone.The maize plant biomass,grain yield,and total N uptake increased significantly by 23%,17%,and 15%,respectively,in the treatment with urea and nitrapyrin,relative to the treatment with urea alone,which was possibly due to N saving,lower N loss,and increased N uptake in the form of ammonium;they were further enhanced in the treatment with urea,nitrapyrin,and GA_3 by 27%,36%,and 25%,respectively,probably because of the stimulating effect of GA_3 on plant growth and development and the reduction in biotic and abiotic stresses.These results suggest that applying urea in combination with nitrapyrin and GA_3 has the potential to mitigate N_(2)O emission,improve N response efficiency,and increase maize yield. | Khadim DAWAR Kamil SARDAR Mohammad ZAMAN Christoph MÜLLER Alberto SANZ-COBENA Aamir KHAN Azam BORZOUEI Ana Gabriela PÉREZ-CASTILLO | 2021 | Pedosphere2021，31，2： | 2 |
| 4 | 经验证的多基因风险评分对中青年人冠状动脉粥样硬化性心脏病长期风险的预测作用显示文摘本文旨在了解先前获得的多基因风险评分(polygenic risk scores, PRS)对冠状动脉粥样硬化性心脏病(冠心病)长期风险的预测效用及其超越传统危险因素的附加价值,为预防策略提供信息。方法:纳入Framingham后代研究(Framingham offspring study, FOS)和社区动脉粥样硬化风险(atherosclerosis risk in communities, ARIC)研究中年龄20~59岁无冠心病的成年人数据进行分析。 | Khan SS Page C Wojdyla DM Schwartz YY Greenland P Pencina MJ 刘青(译) 郑武洪(审校) | 2022 | 中华高血压杂志2022，30，12： | 2 |
| 5 | Locally transplanted enteric glia improve functional and structural recovery in a rat model of spinal cord injury显示文摘<正>BACKGROUND:We have previously reported that adult enteric glia(EG) facilitate the growth of transected dorsal root axons into the uninjured spinal cord to form functional connections with their targets. OBJECTIVE:The present study investigated the effects of EG on spinal cord function,tissue injury, and axonal regeneration following transplantation into injured rat spinal cords,according to histological and functional outcomes. DESIGN,TIME AND SETTING:A randomized controlled animal experiment was performed at McMaster University,Canada from January 2006 to March 2008. MATERIALS:EG were isolated from rat intestine. METHODS:One week following spinal cord crush,female Wistar rats were injected with an EG suspension(2μL,1×10~5/μL,n=10) or with the same volume of fresh culture medium alone(control animals,n=11).The third group did not receive any injection following laminectomy and served as the sham-operated controls(n=5). MAIN OUTCOME MEASURES:Behavior was tested prior to transplantation and weekly following transplantation,with nine behavioral examinations in total.Open field,hind limb placement response, foot orientation response,and inclined plane test were utilized.Immediately following the final behavioral examination,spinal cord T_9 to L_1 segments were harvested for immunohistochemical and hematoxylin-eosin staining to determine astroglial scarring,axonal regeneration and spinal cord lesion size. RESULTS:Rats with EG transplantation exhibited significantly better locomotor function with reduced tissue damage,compared with the control rats.Cystic cavities were present 2 months after injury in spinal cords from both control groups.In contrast,rats injected with EG did not present with cystic lesions.In addition,the injury site consisted of cellular material and nerve fibers,and axonal regeneration was apparent,with dense labeling of neurofilament-positive axons within the injury site. Moreover,regenerating axons were intimately associated with transplanted EG CONCLUSION:These data indicated that EG enhanced functional improvement,which was associated with reduced tissue damage and axonal regeneration following transplantation into injured spinal cords. | Shucui Jiang Mohammad I. Khan James R. Bain Cai Jiang Christopher R. Hansebout Zesheng Yu Yuqing Liu Michel P, Rathbone | 2009 | Neural Regeneration Research2009，4，9： | 2 |
| 6 | GABAA receptor subunit expression changes in the rat cerebellum and cerebral cortex during aging显示文摘 | Gutierrez A Khan Z U Miralles C P | 1997 | Mol Brain Res1997，45，1： | 1 |
| 7 | Intermittent cyclic process for enhanced biological nutrient removal treating combined chemical laboratory wastewater 显示文摘 | Tanwar P Nandy T Khan R | 2007 | Bioresour Techno12007，98，13： | 1 |
| 8 | Crosslinkable fumed silica-based nanocomposite electrolytes:role of methacrylate mono-mer in formation of crosslinked silica network显示文摘 | Yerian J A Khan S A Fedkiw P S | 2004 | J PowerSources2004，135，12： | 1 |
| 9 | Influence of plant age, whitefly population and cultivar resistance on infection of cotton plants by cotton leaf curl virus(CLCuV) in Pakistan 显示文摘 | Akhtar K P Hussain M Khan A I | 2004 | Field Crops Research2004，86，1： | 1 |
| 10 | A Molecular linkage map of tomato displaying chromosomal locations resistance gene analogs based on a Lycopersicon esculentum× Lycopersicon hirsutum cross显示文摘 | Zhang L P Khan A Nino-Liu D | 2002 | Genome2002，45，1： | 1 |
| 11 | Flow of ductile iron through ceramic filters and the effects on the dross and fatigue properties显示文摘 | Khan P R Su W M | 1987 | AFS Transactions1987，，95： | 1 |
| 12 | Large volume ' mammotome' biopsy may reduce the need for diagnostic surgery in papillary lesions of the breast显示文摘 | CARDER P J KHAN T BURROWS P | 2008 | J Clin Pathol2008，61，8： | 1 |
| 13 | Down-regulation of survivin byoxaliplatin diminishes radioresistance of head and neck squamouscarcinoma cells显示文摘 | Khan Z Khan N Tiwari R P | 2010 | Radiother Oncol2010，96，2： | 1 |
| 14 | Cemented or uncemented hemiarthroplasty for displaced intracapsular femoral neck fractures显示文摘 | Khan RJ MacDowell A Crossman P | | 0，，： | 1 |
| 15 | Current understanding and importance of histone phosphorylation in regulating chromatin biology显示文摘 | Pérez-Cadahía B Drobic B Khan P | | 0，，05： | 1 |
| 16 | Utilisation of wild gramineous plants for management of cereal stemborers in Africa显示文摘 | Khan Z R Chiliswa P Ampong-Nyarko K | 1997 | International Journal of Tropical Insect Science1997，17，1： | 1 |
| 17 | Cleavage mecha- noluminescence in crystals 显示文摘 | Chandra B P Khan M S Ansari M H | 1988 | Crystal Research and Tech- nology1988，33，2： | 1 |
| 18 | Biomass combustion in fluidized bed boilers:potential problems and remedies显示文摘 | Khan A A Jong W Jansens P J | 2009 | Fuel Processing Technology2009，90，1： | 1 |
| 19 | Molecular structures and metabolic characteristics of protein in brown and yellow flaxseed with altered nutrient traits显示文摘 | KHAN N A BOOKER H YU P | 2014 | J Agric Food Chem2014，62，28： | 1 |
| 20 | Improvement in creep strength in a nickel-base single crystal superalloy by heat treatment 显示文摘 | CARON P KHAN T | 1983 | Mater Sci Eng1983，61，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员