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789篇 您的检索式：作者名="Karl R"

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	题名	作者	年代	出处	被引量
1	Noninvasive detection and evaluation of atherosclerotic coronary plaques with multislice computed tomography 1 1 This study was performed without additional financial support.显示文摘	Stephen Schroeder Andreas F Kopp Andreas Baumbach Christoph Meisner Axel Kuettner Christian Georg Bernd Ohnesorge Christian Herdeg Claus D Claussen Karl R Karsch	2001	Journal of the American College of Cardiology2001，，5：	3
2	Towards a new tuberculosis drug: pyridomycin – nature’s isoniazid显示文摘	Ruben C. Hartkoorn Claudia Sala Jo?o Neres Florence Pojer Sophie Magnet Raju Mukherjee Swapna Uplekar Stefanie Boy‐R?ttger Karl‐Heinz Altmann Stewart T. Cole	2012	EMBO Mol Med2012，，：	2
3	The oral commensal Streptococcus mitis activates the aryl hydrocarbon receptor in human oral epithelial cells显示文摘Streptococcus mitis(S. mitis) is a pioneer commensal bacterial species colonizing many of the surfaces of the oral cavity in healthy individuals. Yet, not much information is available regarding its interaction with the host. We used examination of its transcriptional regulation in oral keratinocytes to elucidate some of its potential roles in the oral cavity. Transcription factor analysis of oral keratinocytes predicted S. mitis-mediated activation of aryl hydrocarbon receptor(Ah R). Activation and functionality of Ah R was confirmed through nuclear translocation determined by immunofluorescence microscopy and real-time polymerase chain reaction with reverse transcription analysis of CYP1A1, the hallmark gene for Ah R activation. Addition of Streptococcus mutans or Streptococcus gordonii did not induce CYP1A1 transcription in the keratinocyte cultures. Introduction of an Ah R-specific inhibitor revealed that S. mitis-mediated transcription of CXCL2 and CXCL8 was regulated by Ah R. Elevated levels of prostaglandin E2(enzyme-linked immunosorbent assay) in supernatants from S. mitis-treated oral epithelial cells were also attenuated by inhibition of Ah R activity. The observed Ah R-regulated activities point to a contribution of S. mitis in the regulation of inflammatory responses and thereby to wound healing in the oral cavity. The concept that the oral commensal microbiota can induce Ah R activation is important, also in view of the role that Ah R has in modulation of T-cell differentiation and as an anti-inflammatory factor in macrophages.	stian a engen gro h rørvik olav schreurs inger js blix karl schenck	2017	International Journal of Oral Science2017，9，3：	2
4	Pancreatic cancer cells surviving gemcitabine treatment express markersof stem cell differentiation and epithelial-mesenchymal transition显示文摘	Karl Quint Manuel Tonigold Pietro Di Fazio Roberta Montalbano Susanne Lingelbach Felix Rückert Beate Alinger Matthias Ocker Daniel Neureiter	2012	International Journal of Oncology2012，，6：	2
5	Peroral Endoscopic Myotomy for the Treatment of Achalasia: An International Prospective Multicenter Study显示文摘	Daniel Von Renteln Karl–Hermann Fuchs Paul Fockens Peter Bauerfeind Melina C. Vassiliou Yuki B. Werner Gerald Fried Wolfram Breithaupt Henriette Heinrich Albert J. Bredenoord Jan F. Kersten Tessa Verlaan Michael Trevisonno Thomas R?sch	2013	Gastroenterology2013，，2：	2
6	A new perspective on recent global warming:A symmetric trends of daily maximum and minimum temperature显示文摘	Thomas R Karl Richord W Knight Kevin P Callo	1993	Bulletin of the American Meteorological Society1993，74，6：	2
7	Influence of heart rate on vessel visibility in noninvasive coronary angiography using new multislice computed tomography显示文摘	Stephen Schroeder Andreas F Kopp Axel Kuettner Christof Burgstahler Christian Herdeg Martin Heuschmid Andreas Baumbach Claus D Claussen Karl R Karsch Ludger Seipel	2002	Clinical Imaging2002，，2：	2
8	Rheumatoid factor revisited显示文摘	Thomas D?rner Karl Egerer Eugen Feist Gerd R Burmester	2004	Current Opinion in Rheumatology2004，，3：	2
9	The pathophysiology and treatment of sepsis显示文摘	Hotchkiss R S Karl I E	2003	New England Journal of Medicine2003，348，2：	1
10	Comparison of synthetic surfactants and biosurfactants in enhancing biodegradation of polycyclic aromatic hydrocarbons显示文摘	RANDHIR S M KARL J R	2003	Envionmental Toxicology and Chemical2003，22，10：	1
11	A new perspec-tive on recent global warming:Asymmetric of dailymaximum and minimum temperature显示文摘	Karl T RJ ones P D Knight R We t al	1993	Bulletin of theAmerican Meteorological Society1993，74，6：	1
12	An introduction to trends in extreme weather and climate events: observations, socio-economic impacts, terrestrial ecological impacts, and model projections显示文摘	Meehl G A Karl T Easterling D R	2000	Bulletin of the American Mathematical Society2000，81，3：	1
13	Efflux of dietary flavonoid quercetin 4'-β-glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistanceassociated protein2显示文摘	Richard A W Karl J R George E L	2000	J Pharm Exp Ther2000，294，3：	1
14	Absolute atomic oxygen density profiles in the discharge core of a microscale atmospheric pressure plasma jet显示文摘	Nikolas K Karl N Stephan R	2008	Applied Physics Letters2008，93，13：	1
15	Climate extremes:Selected review and future research directions显示文摘	KARL T R EASTERLING D R	1999	Climatic change1999，42，1：	1
16	The role of nitrogen fixation in biogeochemical cycling in the subtropical North Pacific Ocean显示文摘	Karl D Letelier R Tupas L	1997	Nature1997，388，：	1
17	The pathophysiology and treatment ofsepsis显示文摘	Hotchkiss R S Karl I E	2003	N Engl J Med2003，348，2：	1
18	Ultrasound biomicroscopy in chronic ocular hypotony:its impact on diagnosis and management显示文摘	Sigrid R Peter S Bert E Karl BS Gunter K	2002	Retina2002，22，5：	1
19	The use of a vegetation index for assessment of the urban heat island effect 显示文摘	Gallo K P L Mcnab A Karl T R	1993	Int J Remote Serving1993，14，11：	1
20	Littoral periphyton responses to nitrogen and phosphorus: an experimental study in a subtropical lake显示文摘	Karl E Therese L E Andrew J R	1999	Aquatic Botany1999，，63：	1

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