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| 1 | 静脉血栓栓塞症的抗血栓治疗:美国《胸科学》杂志指南显示文摘包括深静脉血栓和肺栓塞在内的静脉血栓栓塞症是癌症患者的主要并发症,发生率为4%~20%,并且是常见的潜在致命性急症。本文介绍了美国《胸科学》杂志指南中VET的抗血栓治疗的部分内容,其以第9版《美国胸内科医师学会循证临床实践指南》中的《静脉血栓栓塞症的抗血栓治疗:抗血栓治疗和阻止血栓形成》一文为参照,基于静脉血栓栓塞症治疗的Ⅲ期试验的发表年份,对口服抗凝剂(达比加群、利伐沙班、阿哌沙班、依度沙班)进行先后阐述(但是这一排序并不是指南专家组对药剂的优劣排序),以为临床医生提供参考。 | Kearon C Akl EA Ornelas J Blaivas A Jimenez D Bounameaux H Huisman M King CS MorrisT Sood N Stevens SM Vintch JRE Wells P Woller SC Moores CL 本刊编辑部 | 2016 | 中国全科医学2016，19，9： | 10 |
| 2 | 四川汶川Ms 8.0级地震的同震位移量显示文摘2008年5月12日四川汶川映秀发生了旷世罕见的8.0级大地震。这次强震发生在青藏高原东部与四川盆地之间的龙门山断裂带,其主震震级之大、余震次数之多令世人震惊。大震后2个多月发生余震1.8万余次,其中最强的余震震级达6.4级。 | 刘宇平 张清志 唐文清 陈智梁 赵济湘 潘忠习 R W King B C Burchfiel | 2008 | 地质通报2008，27，12： | 5 |
| 3 | SLC26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct显示文摘Pendred syndrome(PS) is characterized by autosomal recessive inheritance of goiter associated with a defect of iodide organification, hearing loss, enlargement of the vestibular aqueduct(EVA), and mutations of the SLC26A4 gene. However, not all EVA patients have PSor SLC26A4 mutations. Two mutant alleles of SLC26A4 are detected in 1/4 of North American or European EVA populations, one mutant allele is detected in another 1/4 of patient populations, and no mutations are detected in the other 1/2. The presence of two mutant alleles of SLC26A4 is associated with abnormal iodide organification, increased thyroid gland volume, increased severity of hearing loss, and bilateral EVA. The presence of a single mutant allele of SLC26A4 is associated with normal iodide organification, normal thyroid gland volume, less severe hearing loss and either bilateral or unilateral EVA. When other underlying correlations are accounted for, the presence of a cochlear malformation or the size of EVA does not have an effect on hearing thresholds. This is consistent with observations of an Slc26a4 mutant mouse model of EVA in which hearing loss is independent of endolymphatic hydrops or inner ear malformations. Segregation analyses of EVA in families suggest that the patients carrying one mutant allele of SLC26A4 have a second, undetected mutant allele of SLC26A4, and the probability of a sibling having EVA is consistent with its segregation as an autosomal recessive trait. Patients without any mutations are an etiologically heterogeneous group in which siblings have a lower probability of having EVA. SLC26A4 mutation testing can provide prognostic information to guide clinical surveillance and management, as well as the probability of EVA affecting a sibling. | Taku Ito Julie Muskett Parna Chattaraj Byung Yoon Choi Kyu Yup Lee Christopher K Zalewski Kelly A King Xiangming Li Philine Wangemann Thomas Shawker Carmen C Brewer Seth L Alper Andrew J Griffith | 2013 | World Journal of Otorhinolaryngology2013，3，2： | 2 |
| 4 | Stability of fruit quality traits in diverse watermelon cultivars tested in multiple environments显示文摘Lycopene is a naturally occurring red carotenoid compound that is found in watermelon.Lycopene has antioxidant properties.Lycopene content,sugar content and hollowheart resistance are subject to significant genotype×environment interaction(G×E),which makes breeding for these fruit quality traits difficult.The objectives of this study were to(i)evaluate the influence of years and locations on lycopene content,sugar content and hollowheart resistance for a set of watermelon genotypes,and(ii)identify genotypes with high stability for lycopene,sugar,and hollowheart resistance.A diverse set of 40 genotypes was tested over 3 years and 8 locations across the southern United States in replicated,multi-harvest trials.Lycopene was tested in a subset of 10 genotypes.Data were analyzed using univariate and multivariate stability statistics(BLUP-GGE biplot)using SASGxE and RGxE programs.There were strong effects of environment as well as G×E interaction on watermelon quality traits.On the basis of stability measures,genotypes were classified as stable or unstable for each quality trait.'Crimson Sweet'is an inbred line with high quality trait performance as well as trait stability.'Stone Mountain','Tom Watson','Crimson Sweet'and'Minilee'were among the best genotypes for lycopene content,sugar content and hollowheart resistance.We developed a stability chart based on marketable yield and average ranking generated from different stability measures for yield attributes and quality traits.The chart will assist in choosing parents for improvement of watermelon cultivars.See http://gffzz783b6e01a04243c3hnco0bvnquf9q696k.ffgz.tsg.suse.edu.cn/cucurbit/wmelon/wmelonmain.html. | Mahendra Dia Todd C Wehner Penelope Perkins-Veazie Richard Hassell Daniel S Price George E Boyhan Stephen M Olson Stephen R King Angela R Davis Gregory E Tolla Jerome Bernier Benito Juarez | 2016 | Horticulture Research2016，3，1： | 2 |
| 5 | Experimental investigation of stepped tip gap effects on the performance of a transonic axial-flow Compressor Rotor显示文摘 | THOMPSON D W KING P I RABE D C | 1998 | ASME Journal of Turbomachinery1998，120，： | 1 |
| 6 | A double-blind, placebocontrolled trial of sertraline for depressive symptoms in patients with stable,chronic schizophrenis 显示文摘 | Mulholland C Lynch G King D J | 2003 | J Psychopharmacol2003，17，： | 1 |
| 7 | Flight Control Actuation Technology for Next--Generation All-- Electric Aircraft显示文摘 | Botten S L Whitley C R King A D | 2000 | Technology Review Journal-- Millennium Issue2000，，3： | 1 |
| 8 | SchrSdinger cat superposition state of an atom 显示文摘 | Monroe C Meekhof D M King B E | 1996 | Science1996，272，： | 1 |
| 9 | New insights into the differentiation and function of T follicular helper cells显示文摘 | King C | 2009 | Nat Rev Immunol2009，9，11： | 1 |
| 10 | Bow elbow (cubitus varus)显示文摘 | Secor C | 1995 | J Bone Joint Surg Am1995，77，7： | 1 |
| 11 | Local-scale fluxes of carbon dioxide in urban, environments : methodological challenges and results from Chicago 显示文摘 | Gtimmond C S B King T S Cropley F D | 2002 | Environ Poll2002，116，： | 1 |
| 12 | The application of remotesensing data to monitoring and modeling of soil erosion 显示文摘 | King C Baghdadi N Lecomte V | 2005 | CATENA2005，，62： | 1 |
| 13 | Anthocyanin, phenolic composition, colour measurement and sensory analysis of BC commercial red wines显示文摘 | CLIFF M A KING M C SCHLOSSER J | 2007 | Food Research International2007，40，1： | 1 |
| 14 | Evaluation of Newcastle disease virus chimeras expressing the Hemagglutinin-Neuraminidase protein of velogenic strains in the context of a mesogenic recombinant virus backbone显示文摘 | Estevez C King D Seal B Yu Q | 2007 | Virus Res2007，129，2： | 1 |
| 15 | Evaluation of Newcas- tle disease virus chimeras expressing the Hemagglutinin-Neu- raminidase protein of velogenic strains in the context of a meso- genic recombinant virus backbone 显示文摘 | Estevez C King D Yu Qing-zhou | 2007 | Virus Res2007，129，： | 1 |
| 16 | Schematic method of deriving the rate laws for enzyme-catalyzed reactions显示文摘 | King E L Altman C A | 1956 | J Phys Chem1956，60，： | 1 |
| 17 | Assembly of foot-and- mouth disease virus empty capids synthesized by a vaccinia virus expression system显示文摘 | Abrams C C King A M Belsham G J | 1995 | J Gen Virol1995，76，： | 1 |
| 18 | Relation between stillbirth and specific chlorination by-products in public water supplies显示文摘 | WILL D KING LINDA DODDS ALEXANDER C ALLEM | 2000 | Environmental Health Perspectives2000，108，9： | 1 |
| 19 | The growth of geological structures by repeated earthquakes,1,Conceptual framework显示文摘 | king G C Stein R S Rundle J B | 1988 | Journal of Geophysical Research1988，93，13： | 1 |
| 20 | Augmendation of parasites and predators for suppression of arthropod pests 显示文摘 | King E C | 1993 | Proceeding of Beltsville Symposium1993，28，： | 1 |
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