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| 1 | Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients. | Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton | 2008 | World Journal of Gastroenterology2008，14，3： | 4 |
| 2 | Evening Primrose Oil and Treatment of Premenstrual Syndrome显示文摘 | Khoo S K Munro C Battistutta D | 1990 | The Medical Journal of Australia1990，153，4： | 1 |
| 3 | Iatrogenic parasitic myomas : unusual late complication of laparoscopic momellation procedures 显示文摘 | Larrain D Rabischong B Khoo CK | 2010 | J Minim Invasive Gynecol2010，17，6： | 1 |
| 4 | Lyotropic liquid crystalline phases formed from glycerate surfactants as sustained release drug delivery systems显示文摘 | Boyd B J Whittaker D V Khoo S M | 2006 | Int J Pharm2006，309，： | 1 |
| 5 | Ki-67 staining is an independent correlate of biochemical failure in prostate cancer treated with radiotherapy 显示文摘 | Cowen D Troncoso P Khoo VS | 2002 | Clin Cancer Res2002，8，5： | 1 |
| 6 | Ink4a/Arf tumor suppressor does notmodulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse 显示文摘 | KHOO C M CARRASCO D R Bosenberg M W | 2007 | Proceedings of the National Academy of Sciences of Untied States of America2007，104，10： | 1 |
| 7 | Iatrogenic parasitic myo- mas:unusual late complication of laparoscopic morcellation procedures 显示文摘 | Larra'n D Rabischong B Khoo CK | 2010 | J Minim Invasive Gyneco12010，17，6： | 1 |
| 8 | Production of bioactive amino-terminal domain of the thyrotropin receptor via insertion in the plasma membrane by a glycosylphosphatidylinositol anchor显示文摘 | Khoo D Vassart G | 1998 | FEBS Lett1998，436，3： | 1 |
| 9 | An immersed interface method for viscous incompressible flows involving rigid and flexible boundaries显示文摘 | Le D V Khoo B C Peraire J | 2006 | Journal of Computational Physics2006，220，1： | 1 |
| 10 | Triple degree of freedom piezoelectric ultrasonic micromotor via flexural-axial coupled vibration 显示文摘 | Khoo T F Dang D H Friend J | 2009 | IEEE Trans Ultrason Ferroelec Freq Contr2009，56，8： | 1 |
| 11 | An immune algorithm approach to the scheduling of a flexible PCB flow shop显示文摘 | Alisantoso D Khoo L P Jiang P Y | 2003 | Advanced Manufacturing Technology2003，22，： | 1 |
| 12 | Magnetic resonance imaging (MRI) : considerations and applications in radiotherapy treatment planning 显示文摘 | KHOO V S DEARNALEY D P FINNIGAN D J | 1997 | Radiother Oncol1997，42，1： | 1 |
| 13 | Interferon-alpha in the treatment of multiple myeloma显示文摘 | Khoo TL Vangsted AJ Joshua D | 2011 | Curr Drug Targets2011，12，3： | 1 |
| 14 | The specif- ic load capacity of Radial-Flux radial magnetic bearings显示文摘 | KHOO W K S GARVEY S D KALITA K | 2007 | IEEE Transaction on Magnetics2007，43，7： | 1 |
| 15 | The effects of problem-basedlearning duringmedical school on physician competency: asystematicreview显示文摘 | Koh GG Khoo HE Wong ML Koh D | 2008 | CMAJ2008，，178： | 1 |
| 16 | Electroless plating of noblemetal nanoparticles for improved performance of silicon pho-todiodes via surface plasmon resonance显示文摘 | BLACKWOOD D J KHOO S M | 2010 | Sol Energ MatSol:C2010，94，7： | 1 |
| 17 | Subclinical varicocele:the effectiveness of varicocelectomy显示文摘 | Moclure RD Khoo D Jarvi K | | 0，，04： | 1 |
| 18 | Pharmacokineties and drug- drug interactions of antiretrovirals: An update 显示文摘 | DICKINSON L KHOO S BACK D | 2010 | Antiviral Res2010，85，1： | 1 |
| 19 | Nanosphere dispersed liquid crystals for tunable negative-zero-positive index of refraction in the optical and terahertz regimes显示文摘 | Khoo I C Werner D H Liang X | 2006 | Opt Lett2006，31，17： | 1 |
| 20 | Liquid crystal clad near-infrared metamaterials with tunable negative-zero-positive refractive indices显示文摘 | Werner D H Do-Hoon Kwon Iam-Choon Khoo | 2007 | Opt Express2007，15，16： | 1 |
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