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| 1 | Mobilization of hematopoietic progenitor cells in patients with liver cirrhosis显示文摘AIM:To test the hypothesis that liver cirrhosis is associated with mobilization of hematopoietic progenitor cells. METHODS:Peripheral blood samples from 72 patients with liver cirrhosis of varying etiology were analyzed by flow cytometry.Identified progenitor cell subsets were immunoselected and used for functional assays in vitro. Plasma levels of stromal cell-derived factor-1(SDF-1) were measured using an enzyme linked immunosorbent assay.RESULTS:Progenitor cells with a CD133 + /CD45 + CD14 + phenotype were observed in 61%of th patients.Between 1%and 26%of the peripheral bloo mononuclear cells(MNCs)displayed this phenotype Furthermore,a distinct population of c-kit + progenito cells(between 1%and 38%of the MNCs)could b detected in 91%of the patients.Additionally,18% of the patients showed a population of progenito cells(between 1%and 68%of the MNCs)that wa characterized by expression of breast cancer resistanc protein-1.Further phenotypic analysis disclosed tha the circulating precursors expressed CXC chemokin receptor 4,the receptor for SDF-1.In line with thi finding,elevated plasma levels of SDF-1 were presen in all patients and were found to correlate with th number of mobilized CD133 + progenitor cells. | Ursula M Gehling Marc Willems Kathleen Schlagner Ralf A Benndorf Maura Dandri Jrg Petersen Martina Sterneck Joerg-Matthias Pollok Dieter K Hossfeld Xavier Rogiers | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 2 | Prediction of delayed graft function using different scoring algorithms: A single-center experience显示文摘AIM To compare the performance of 3 published delayed graftfunction(DGF) calculators that compute the theoretical risk of DGF for each patient.METHODS This single-center,retrospective study included 247 consecutive kidney transplants from a deceased donor.These kidney transplantations were performed at our institution between January 2003 and December 2012.We compared the occurrence of observed DGF in our cohort with the predicted DGF according to three different published calculators. The accuracy of the calculators was evaluated by means of the c-index(receiver operating characteristic curve).RESULTS DGF occurred in 15.3% of the transplants under study.The c index of the Irish calculator provided an area under the curve(AUC) of 0.69 indicating an acceptable level of prediction,in contrast to the poor performance of the Jeldres nomogram(AUC = 0.54) and the Chapal nomogram(AUC = 0.51). With the Irish algorithm the predicted DGF risk and the observed DGF probabilities were close. The mean calculated DGF risk was significantly different between DGF-positive and DGF-negative subjects(P < 0.0001). However,at the level of the individual patient the calculated risk of DGF overlapped very widely with ranges from 10% to 51% for recipients with DGF and from 4% to 56% for those without DGF.The sensitivity,specificity and positive predictive value of a calculated DGF risk ≥ 30% with the Irish nomogram were 32%,91% and 38%. CONCLUSION Predictive models for DGF after kidney transplantation are performant in the population in which they were derived,but less so in external validations. | Magda Michalak Kristien Wouters Erik Fransen Rachel Hellemans Amaryllis H Van Craenenbroeck Marie M Couttenye Bart Bracke Dirk K Ysebaert Vera Hartman Kathleen De Greef Thiery Chapelle Geert Roeyen Gerda Van Beeumen Marie-Paule Emonds Daniel Abramowicz Jean-Louis Bosmans | 2017 | World Journal of Transplantation2017，7，5： | 3 |
| 3 | Cellular location of transforming growth factor β1 expression in bleomycin-induced pulmonary fibrosis显示文摘 | Kathleen C Flander S | 1995 | Am J Pathol1995，147，： | 1 |
| 4 | Factors associated with death or hospitalization due to pandemic 2009 inlfuenza a (H1N1) infectionin california显示文摘 | Janice K Louie Meileen Acosta Kathleen Winter | | 0，，17： | 1 |
| 5 | The effect of phytosterol concentration on oxidative stability and thermal polymerization of heated oils显示文摘 | WINKLER J K KATHLEEN W | 2008 | Eur J Lipid Sci Technol2008，110，： | 1 |
| 6 | Glucose Metabolism in 105 Children and Adolescents After Pancreatectomy for Congenital Hyperinsulinism显示文摘 | Beltrand Jacques Caquard Marylène Arnoux Jean-Baptiste Laborde Kathleen Velho Gilberto Verkarre Virginie Rahier Jacques Brunelle Francis Nihoul-Fékété Claire Saudubray Jean-Marie Robert Jean-Jacques de Lonlay Pascale | 2012 | Diabetes Care2012，，2： | 1 |
| 7 | Identification and characterization of proteins involved in rice urea and arginine catabolism显示文摘 | Feng-Qiu Cao Andrea K W Kathleen D | 2010 | Plant Physiology2010，154，： | 1 |
| 8 | Identification of overexpression of orphan G protein-coupled receptor GPR49in human colon and ovarian primary tumors显示文摘 | McClanahan T Sandra K Kathleen S | 2006 | Cancer Biol2006，5，4： | 1 |
| 9 | Clinical Teaching Effectiveness Described in Relation to Learning Outcomes of Baccalaureate Nursing Students显示文摘 | Kathleen K | 1994 | Journal of Nursing Education1994，33，7： | 1 |
| 10 | Performance monitoring and stop signal inhibition in abstinent patients with cocaine dependence显示文摘 | Chiang-shan Ray L Verica M Kathleen K | 2006 | Drug Alcohol Depend2006，，85： | 1 |
| 11 | Theoretical and experimental considerations for interpretationof amide I bands in tissue 显示文摘 | KATHLEEN M G LSAN T MARZENA Z K | 2011 | Vibrational Spectroscopy2011，53，1： | 1 |
| 12 | The Use of Tympanometry and Pneumatic Otoscopy for Predicting Middle Ear Disease显示文摘 | Paula K Kathleen M Joseph J | 2005 | Am J Audiol2005，14，6： | 1 |
| 13 | Long-term safety and once-daily niacin/lovastatin formulation for patients with dyslipidemia 显示文摘 | Moti L K Mark E M Kathleen B | 2002 | Am J Cardiol2002，89，6： | 1 |
| 14 | Cost-effectiveness of rosuvastatinin comparison withgeneric atorvastatin and simvastatin in a Swedish popu-lationat high risk of cardiovascular events显示文摘 | Sanjay K Gandhi Marie M Jensen Kathleen M Fox? etal | 2012 | Clinico-Economics and Outcomes Research ?2012 ?4:1-112012，4，： | 1 |
| 15 | Reduction of Epidural Fibrosis in Lumbar Surgery with Oxiplex Adhesion Bar-riers of Carboxymethylcellulose and Polyethylene Oxide显示文摘 | Rodgers K E Kathleen E Robertson J T | 2003 | The Spine Journal2003，3，4： | 1 |
| 16 | Antifungal activity of redox-active benzaldehydes that target cellular antioxidation显示文摘 | Jong H K Kathleen L C Noreen M | 2011 | Ann Clin Microbiol Antimicrob2011，10，： | 1 |
| 17 | Influence of fiber surface characteristics on the flax/polypropylene interface 显示文摘 | KATHLEEN V V PAUL K | 2011 | Journal of Thermoplastic Composite Materials2011，14，： | 1 |
| 18 | Immuneregulation of a chronic bacteria infectionand consequences forpathogen transmission显示文摘 | ASHUTOSH K P KATHLEEN EC JACOB RW | 2010 | BMC Microbiology2010，10，： | 1 |
| 19 | The effects of obesity and body fat distribution on lipids and lipoproteins in nondiabetic American Indians:the strong heart study显示文摘 | Dongsheng Hu Kathleen A Joblonski Thomas K Welty | 2000 | Obesity Research2000，8，6： | 1 |
| 20 | 17 β-estradiol acts directly on the clonal osteoblastic cell line UMR 106显示文摘 | GRAY T K TIMOTHY C F KATHLEEN M G | 1987 | Proc Natl Acad Sci1987，84，17： | 1 |
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