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| 1 | Hepatoprotective activity of Hepax-A polyherbal formulation显示文摘Objective:To evaluate the hepatoprotective potential of Hepax,a polyherbal formulation,against three experimentally induced hepatotoxicity models in rats.Methods:Hepatoprotective activity of Hepax was studied against three experimentally induced hepatotoxicity models,namely, carbon tetrachloride(CCl_4),paracetamol and thiocetamide induced hepatotoxicity in rats. Results:Administration of hepatotoxins(CCl_4,paracetamol and thiocetamide) showed significant morphological,biochemical and histological deteriorations in the liver of experimental animals. Pretreatment with Hepax had significant protection against hepatic damage by maintaining the morphological parameters(liver weight and liver weight to organ weight ratio) within normal range and normalizing the elevated levels of biochemical parameters(SGPT,SCOT,ALP and total bilirubin),which were evidently showed in histopathological study.Conclusions:The Hepax has highly significant hepatoprotective effect at 100 and 200 mg/kg,p.o.on the liver of all the three experimental animal models. | VC Devaraj B Gopala Krishna GL Viswanatha Jagadish V Kamath Sanjay Kumar | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，2： | 4 |
| 2 | Continuing episodes of pain in recurrent acute pancreatitis: Prospective follow up on a standardised protocol with drugs and pancreatic endotherapy显示文摘AIM To assess the outcomes of drug therapy(DT)followed by pancreatic endotherapy for continuing painful episodes in recurrent acute pancreatitis.METHODS DT comprised of pancreatic enzymes and antioxidants failing which,endotherapy(ET;pancreatic sphincterotomy and stent placement)was done.The frequency of pain,its visual analogue score(VAS),quality of life(Qo L),serum C peptide and faecal elastase were compared between baseline and after 1 year of follow up in all patients and in the two subgroups on DT and ET.Response was defined as at least 50%reduction in the severity of pain to below a score of 5.RESULTS Of the thirty nine patients analysed,21(53.9%)responded to DT and 18(46.1%)underwent ET.The VAS for pain(7.0±2.0 vs 1.3±2.5,P<0.001)and the number of days with pain per month decreased[1.0(1.0,2.0)vs 1.0(0.0,1.0),P<0.001],and the Qo L scores[55.0(44.0,66.0)vs 38.0(32.00,51.00),P<0.01]improved significantly during follow up.Similar significant improvements were seen in patients in the subgroups of DT and ET except for Qo L in ET.The serum C-peptide(P=0.001)and FE(P<0.001)levels improved significantly in the entire group and in the two subgroups of patients except for the C peptide levels in patients on DT.CONCLUSION A standardised protocol of DT,followed by ET decreased the intensity and frequency of pain in recurrent acute pancreatitis,enhanced Qo L and improved pancreatic function. | C Ganesh Pai M Ganesh Kamath Mamatha V Shetty Annamma Kurien | 2017 | World Journal of Gastroenterology2017，23，19： | 2 |
| 3 | The BuddChiari syndrome显示文摘 | Menon K V Shah V Kamath P S | 2004 | N Engl J Med2004，350，6： | 1 |
| 4 | Risk factors assessment of the difficult intubation using intubation difficulty scale (IDS)显示文摘 | K Nasa V S Kamath S | 2014 | J Clin Diagn Res2014，8，7： | 1 |
| 5 | On the performance of stabilized a-nickel hydroxide as a nickel-positive electrode in alkaline storage batteries 显示文摘 | KUMAR V G MUNICHANDRAIAH N KAMATH P V SHUKLA A K | 1995 | Journal of Power Sources1995，56，： | 1 |
| 6 | Production of high solids acrylic coating resin with t - amyl peroxides: a new way to meet VOC requirements 显示文摘 | V R Kamath J D Sargent Jr | 1987 | Journal of Coatings Technology1987，59，746： | 1 |
| 7 | Nitric oxide in liver transplantation: pathobiology and clinical implications 显示文摘 | Shah V Kamath PS | 2003 | Liver Transpl2003，9，1： | 1 |
| 8 | 显示文摘 | Ramesh T N Jayashree R S Kamath P V | 2002 | J Power Sources2002，104，2： | 1 |
| 9 | Desvenlafaxine succinate for ma- jor depressive disorder a critical review of the evidence显示文摘 | KAMATH J HANDRATTA V | 2008 | Ex- pert Rev Neurother2008，8，12： | 1 |
| 10 | Clinical evaluation of hip joint in sagittal plane using pelvifemoral angle 显示文摘 | Kamath BJ Saraswati V Bansal A | 2013 | J Clin Orthopaed Trauma2013，4，4： | 1 |
| 11 | Electrochemical deposition of Cu2O on stainless steel substrates:Promotion and suppression of oriented crystallization显示文摘 | JOSEPH S KAMATH P V | 2008 | Solid State Sci2008，10，： | 1 |
| 12 | Nitric oxide in liver transplantation : Patho- biology and clinical implications 显示文摘 | Shah V Kamath PS | 2003 | Liver Transpl2003，9，： | 1 |
| 13 | Aging of trivalent metal hydroxide/oxide gels in divalent metal salt solutions: Mechanism of formation of layered double hydroxides (LDHs)显示文摘 | A V Radha P Vishnu Kamath | 2003 | Bulletin of Materials Science2003，，7： | 1 |
| 14 | Biomeehanical comparison of interfragmentary compression in transverse fractures of the olee- ranon 显示文摘 | Wilson J Bajwa A Kamath V | 2011 | J Bone Joint Surg Br2011，93，2： | 1 |
| 15 | lso-C3D navigation assisted pedicle screw placement in deformities of the cervical and thoracic spine 显示文摘 | V Rajan V Kamath V Shetty AP | 2010 | Indian J Orthop2010，44，2： | 1 |
| 16 | Study of asp Halt/asphaltene precipitation during addition of solvents to West Sak crude显示文摘 | Jiang J C Patil S L Kamath V A | 1990 | Preprints Div Petrol Chem ACS1990，17，3： | 1 |
| 17 | On the relationship between c~ -nickel hydroxide and the basic salts of nickel 显示文摘 | Rajamathi M Kamath P V | 1998 | J Power Sources1998，70，： | 1 |
| 18 | Maternal milk and serum vitamin B12, folic acid, and protein levels in Indian subjects 显示文摘 | JATHAR V S KAMATH S A PARIKH M N | 1970 | Arch Dis Child1970，45，240： | 1 |
| 19 | Production of high solidsacrylic coating resins with t - amyl peroxides : a new way tomeet VOC requirements 显示文摘 | KAMATH V R SARGENT J D | 1987 | Journal of Coating Technolo-gy1987，59，746： | 1 |
| 20 | Transforming growth factor-betal and TGF-beta2 act synergisti- cally in the fibrotic pathway in oral submucous fibrosis: an im- munohistochemical observation显示文摘 | KAMATH V V KRISHNAMURTHY S SATELUR K P | 2015 | Indian J Med Paediatr Oncol2015，36，2： | 1 |
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