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| 1 | 基于网络信息的暂态稳定性定量分析——支路势能法显示文摘基于结构保持的多机电力系统拓扑暂态能量函数,分析了故障后暂态势能在网络中的分布变化特点,提取出基于网络信息的系统失去稳定时的关键特征量,以构建仅依赖网络信息的以支路势能分析为基础的可定性且可定量评价系统暂态稳定性的方法一支路势能法。该方法建立于电力系统网络信息的动态响应轨迹的基础上,指标的计算简单方便,不仅可用于第一摆、且可应用于多摆的稳定性评价,同时还可用于系统失稳模式、脆弱输电环节的识别,且具有在线应用的潜力。NEW ENGL,AND 10机系统的仿真算例验证了该方法的有效性。 | 蔡国伟 穆钢 K W Chan 卢芳 | 2004 | 中国电机工程学报2004，24，5： | 71 |
| 2 | 长期保护性耕种方式对农田表层土壤性质的影响显示文摘研究了不同耕种方式对澳大利亚同一地区3种土壤表层(0-5cm)理化性质的作用,以揭示保护性耕作对土壤质量恢复的影响。结果表明:免耕穴播/保留残茬(DD/SR)、多年生人工草地(PP)和自然草地(NP)表层土壤的〉2mm水稳性团聚体含量、全氮、有机碳含量、田间持水量均显著高于其相应对照传统耕作/秸秆焚烧(CC/SB)、人工草地/作物轮作(PPC)和耕作(CT)的;土壤全氮含量、田间持水量分别与有机碳含量之间有极显著的正相关关系(r=0.994**,r=0.996**,n=6),而受土壤质地等因素的影响较小;在同一类型的土壤上,土壤有机碳含量与水稳定性团聚体含量之间存在显著的相关性;在不同试验区,耕作措施对表层土壤容重和孑L隙分布的影响存在较大差异;秸秆焚烧和施用石膏对表层土壤的pH及交换性阳离子含量有较大的影响。研究表明长期保护性耕作、草田轮作或多年生草地有利于提高表层土壤有机碳含量和结构稳定性,从而改善土壤的供肥供水能力。 | 张国盛 K Y Chan G D Li D P Heenan | 2008 | 生态学报2008，28，6： | 45 |
| 3 | Management Recommendations on Sleep Disturbance o Patients with Parkinson's Disease显示文摘INTRODUCTION Sleep disturbance is one of the most common nonmotor symptoms in Parkinson's disease (PD).Sleep disturbance affects 40-98% of PD patients in the world. In China, the prevalence of PD patients with sleep disturbance ranges from 47.66% to 89.10%. Sleep disturbance usually has adverse impact on the quality of life of PD patients. Apossible pathogenesis of PD with sleep disturbance include thalamocortical pathway degeneration and changes of neurotransmitter systems. The etiology of sleep disturbance is multifactorial,involving degeneration of areas regulating sleep,sleep structure affected by drugs,sleep disturbance induced by drug,and sleep fragmentation by multiple factors. | Chun-Feng Liu Tao Wang Shu-Qin Zhan De-Qin Geng Jian Wang Jun Liu Hui-Fang Shang Li-Juan Wang Piu Chan Hai-Bo Chen Sheng-Di Chen Yu-Ping Wang Zhong-Xin Zhao K Ray Chaudhuri | 2018 | Chinese Medical Journal2018，，24： | 26 |
| 4 | Estimating liver weight of adults by body weight and gender显示文摘瞄准:为了为估计接枝的足够估计标准肝重量,为癌症在主要肝切除术在实时施主肝移植和残余肝缩放。方法:在这研究,体重和身高的人体测量的数据在 159 个实时的肝施主为与肝重量的关联被测试包括中间的肝的静脉经历了施主权利肝切除术。肝重量从在背表格获得的正确脑叶接枝重量被计算,在计算断层摄影术上由正确脑叶的比例划分了。结果:这些题目,所有汉语,有 35.8+/-10.5 年,和女性的吝啬的年龄到 118:41 的男比率。正确脑叶的吝啬的体积是 710.14+/-131.46 mL 并且在计算断层摄影术上占据了整个肝的 64.55%+/-4.47% 。正确脑叶称了 598.90+/-117.39 g,估计的肝重量是 927.54+/-168.78 g。当体重和身高受到多重逐步的线性回归分析时,身高被发现不足道。一样的体重的女性有稍微更低的肝重量。一个公式基于体重和性被导出:估计的标准肝重量(g)= 218 + BW (kg ) x 12.3 + 性 x 51 (R2 = 0.48 )( 女 = 0,男 = 1 ) 。基于这 159 个题目,的人体测量的数据肝重量用在白种人,日语,朝鲜语,和汉语上从研究导出的以前出版的公式被计算。所有公式与这个公式相比过高估计肝重量。日本公式为成年人过高估计估计的标准肝重量(ESLW ) 不到 60 kg。结论:对中国男性和女性适用的一个公式是可得到的。为单个赛跑的一个公式显得必要。 | See Ching Chan Chi Leung Liu Chung Mau Lo Banny K Lam Evelyn W Lee Yik Wong Sheung Tat Fan | 2006 | World Journal of Gastroenterology2006，12，14： | 22 |
| 5 | Effect of oral erythromycin on gastric and small bowel transit time of capsule endoscopy显示文摘AIM: To determine the effect of oral erythromycin on gastric and small bowel transit time of capsule endoscopy.METHODS: Consecutive patients who underwent capsule endoscopy du ring the 16-mo study period were either given 250 mg oral erythromycin, 1 h prior to swallowing the capsule endoscope or nothing. The gastric and small bowel transit time, and the small bowel image quality were compared.RESULTS: Twenty-four patients received oral erythromycin whereas 14 patients were not given any prokinetic agent.Patients who received erythromycin had a significantly lower gastric transit time than control (16 min vs70 min, P= 0.005),whereas the small bowel transit time was comparable between the two groups (227 min vs183 min, P = 0.18).Incomplete small bowel examination was found in three patients of the control group and in one patient of the erythromycin group. There was no significant difference in the overall quality of small bowel images between the two groups. A marked reduction in gastric transit time was noted in two patients who had repeat capsule endoscopy after oral erythromycin.CONCLUSION: Use of oral erythromycin significantly reduces the gastric transit time of capsule endoscopy. | Wai K Leung Francis KL Chan Sara SL Fung Mei-Yin Wong Joseph JY Sung | 2005 | World Journal of Gastroenterology2005，11，31： | 16 |
| 6 | Combined resection and radiofrequency ablation for multifocal hepatocellular carcinoma: Prognosis and outcomes显示文摘AIM: To analyze the combined treatment of resection and intraoperative radiofrequency ablation (RFA) for multifocal hepatocellular carcinoma in terms of prognosis and surgical outcomes.METHODS: This study was a retrospective case comparison study using prospectively collected data. The study covered the period from April 2001 to December 2006. The data of 200 patients with histologically confirmed hepatocellular carcinoma were reviewed. Nineteen patients (17 men and 2 women) having received resection in combination with RFA were chosen as subjects of the study (the combination group). Fiftyfour patients (43 men and 11 women) having received resection alone were selected for comparison (the resection group). The two groups matched tumor number and tumor size, and all the patients in the two groups displayed no tumor rupture, major vascular involvement and distant metastasis. Their demographics, preoperative assessment, disease recurrence patterns, overall survival and diseasefree survival were compared.RESULTS: In the combination group, the medianage was 65 years (range, 3477 years), the median tumor number was 3 (range, 29), and the median tumor size was 6 cm (range, 1.214 cm). In the resection group, the median age was 51.5 years (range, 2780 years, P = 0.003), the median tumor number was 3 (range, 29, P = 0.574), and the median tumor size was 6 cm (range, 114 cm, P = 0.782). The two groups were similar in characteristics of tumors and comorbidities, and had comparable results in preoperative liver function tests. All patients had ChildPugh class A status. Bilobar involvement occurred in 14 patients (73.6%) in the combination group and 3 patients (5.5%) in the resection group (P = 0.04). Six patients (32%) in the combination group and 35 patients (65%) in the resection group underwent major hepatectomy. Thirteen patients (68%) in the combination group and 19 patients (35%) in the resection group underwent minor hepatectomy (P = 0.012). The combination group had fewer major resections (32% vs 65%, P = 0.012), less blood loss (400 vs 657 mL, P = 0.007), shorter operation time (270 vs 400 min, P = 0.001), and shorter hospital stay (7 vs 8.5 d, P = 0.042). The two groups displayed no major differences in surgical complications (15.8% vs 31.5%, P = 0.24), disease recurrence (63.2% vs 50%, P = 0.673), hospital mortality (5.3% vs 5.6%, P = 1), and overall survival (53 vs 44.5 mo, P = 0.496).CONCLUSION: Safe and effective for selected patients with multifocal hepatocellular carcinoma, the combination of resection and intraoperative RFA widens the applicability of surgical intervention for the disease. | Tan To Cheung Kelvin K Ng Kenneth S Chok See Ching Chan Ronnie T Poon Chung Mau Lo Sheung Tat Fan | 2010 | World Journal of Gastroenterology2010，16，24： | 14 |
| 7 | 绕正方形排列的顺排的四个圆柱的流动研究显示文摘本文通过采用激光诱导荧关技术(LIF),对按正方形排列、边长间距比为4的顺排的四个圆柱的层流绕流进行了流动可视化研究;同时,在Re=200的情况下,对该流场进行了PIV流场测量,两种实验结果吻合良好,显示的都是只在下游圆柱的后面才有漩涡脱落。可是,采用两维有限体积法离散N-S方程计算该流场与实验结果完全不符合,原因尚不清楚。 | 李景银 K Lam K T Chan R M C So | 2004 | 工程热物理学报2004，25，1： | 14 |
| 8 | Photochemical smog in China:scientific challenges and implications for air-quality policies显示文摘INTRODUCTION Severe air-pollution events in many parts of China pose a major threat to health and ecosystems[1].China’s air pollution is concentrated to economically developed areas,such as Beijing–Tianjin–Hebei(BTH)and Pearl–River–Delta(PRD)[2,3].The situation has received considerable attention in | Mattias Hallquist John Munthe Min Hu Tao Wang Chak K Chan Jian Gao Johan Boman Song Guo Asa M Hallquist Johan Mellqvist Jana Moldanova Ravi K Pathak Jan BC Pettersson Hakan Pleijel David Simpson Marie Thynell | 2016 | National Science Review2016，3，4： | 8 |
| 9 | 膳食中钠(盐)与血压的关系及其他膳食因素可能的调节作用显示文摘现有资料表明,膳食钠(盐)与血压直接相关。以往大多数研究结果来自缺乏膳食数据的研究;因此,这种钠-血压关系是否受其他膳食因素调节尚不清楚。国际宏量/微量营养素和血压研究(international study on macro/micronutrients and blood pressure,INTERMAP)结果显示,在控制多种非膳食因素情况下,年龄40~59岁的男性和女性4680人(中国、日本、英国和美国的17个人口样本)的血压与24h尿钠排泄和尿钠/钾直接相关。 | 刘莉 叶鹏 Stamler J Chan Q Daviglus ML Dyer AR Van Horn L Garside DB Miura K Wu Y Ueshima H Zhao L Elliott P INTERMAP Research Group | 2018 | 中华高血压杂志2018，26，4： | 8 |
| 10 | A review on human influenza A H5N1 infections in Hong Kong显示文摘Avian influenza A H5N1 remains the most threatening virus that may cause another devastating pandemic in the foreseeable future. In 1997, Hong Kong was the first place to detect human infections due to this virus originated from birds. The experience and lessons learnt provide important information for controlling further outbreaks caused by avian influenza viruses. | CHAN Paul K S | 2009 | Science China(Life Sciences)2009，52，5： | 7 |
| 11 | Inflammatory bowel disease in Asia: A systematic review显示文摘 | Lani Prideaux Michael A Kamm Peter P De Cruz Francis K L Chan Siew C Ng | 2012 | Journal of Gastroenterology and Hepatology2012，，8： | 5 |
| 12 | 基于网络局部暂态能量的TCSC控制策略的研究显示文摘大扰动下可控硅串联补偿装置控制策略的易实现性、对系统运行方式、故障状态、网络结构的适应性等问题是可控硅串联补偿装置能否实用化的关键。基于结构保持的多机系统的拓扑能量函数,在探索了系统故障后暂态势能在网络中的分布变化特点基础上,提出大扰动下仅依赖于本地输入信号的TCSC(可控硅控制串联补偿)的控制规律,不仅控制规律简单易行,而且在实际系统中的仿真结果表明了该控制规律的有效性。 | 蔡国伟 程浩忠 K W Chan | 2003 | 中国电力2003，36，4： | 4 |
| 13 | 机器人在头颈外科中的应用--香港中文大学经验显示文摘目的:机器人手术目前已在头颈部多个区域得到了应用,本文探讨香港中文大学头颈外科机器人手术的经验。方法:回顾性分析2015年1月以来在香港中文大学耳鼻咽喉头颈外科开展的所有机器人头颈外科手术病例资料。结果:24例患者采用达芬奇S或达芬奇Xi系统进行了手术,21例患者使用新型柔性机器人达芬奇SP系统行了手术。均无二次手术等严重不良事件。已经发表的达芬奇SP系统手术的7例患者早期结果表明,通过达芬奇SP系统可以到达鼻咽、口咽部、下咽部、喉部和咽后淋巴结完成手术,不需中途改变手术方式,没有发生与使用该系统有关的严重不良事件或不良事件。结论:通过我们在香港中文大学的经验,我们认为采用达芬奇机器人系统进行经口手术或经耳后入路颈部手术是安全有效的。 | 陈英权 王维杨 梁发雅 黄晓明 Jason Y K Chan Eddy W Y Wong | 2018 | 临床耳鼻咽喉头颈外科杂志2018，32，14： | 4 |
| 14 | Diagnosing gastrointestinal illnesses using fecal headspacevolatile organic compounds显示文摘Volatile organic compounds(VOCs) emitted from stool are the components of the smell of stool representing the end products of microbial activity and metabolism that can be used to diagnose disease. Despite the abundance of hydrogen, carbon dioxide, and methane that have already been identified in human flatus, the small portion of trace gases making up the VOCs emitted from stool include organic acids, alcohols, esters, heterocyclic compounds, aldehydes, ketones, and alkanes, among others. These are the gases that vary among individuals in sickness and in health, in dietary changes, and in gut microbial activity. Electronic nose devices are analytical and pattern recognition platforms that can utilize mass spectrometry or electrochemical sensors to detect these VOCs in gas samples. When paired with machine-learning and pattern recognition algorithms, this can identify patterns of VOCs, and thus patterns of smell, that can be used to identify disease states. In this review, we provide a clinical background of VOC identification, electronic nose development, and review gastroenterology applications toward diagnosing disease by the volatile headspace analysis of stool. | Daniel K Chan Cadman L Leggett Kenneth K Wang | 2016 | World Journal of Gastroenterology2016，22，4： | 4 |
| 15 | 多机组空调系统部分负荷下的节能策略研究显示文摘针对冷水机组大部分时间都是在部分负荷下运行的现状,提出了一种多机组空调系统并联的节能策略.运用模型仿真和试验验证手段研究节能优化运行策略对机组性能改善效果.试验结果表明:当机组由100%负荷降为50%负荷时,机组的冷凝温度由47.2℃下降到42.5℃,蒸发温度由2.2℃上升到3.5℃,COP值提高9.5%.从而表明该节能策略对多机组空调系统在部分负荷下的性能改善具有较大潜力.同时针对试验结果与仿真结果存在的差距,分析了产生的原因并提出了进一步的改进措施. | 梁彩华 张小松 徐国英 Chan K T | 2008 | 应用基础与工程科学学报2008，16，5： | 3 |
| 16 | Consortium for the Human Information and Neurocognitive Endophenotype (CHINE) in China's Mainland: An example from neurological soft signs for neuropsychiatric disorders显示文摘Increasing efforts to identify alternate expressions of neuropsychiatric disorders that are broader than the DSM or ICD diagnostic criteria needed to diagnose them reflects a growing consensus that multidimensional expressions of neuropsychiatric disorders may advance the search for underlying etiological or modulatory factors. Endophenotypic research can be considered to be one of the most promising strategies to bridge the gap between genomic complexity and the phenotypic heterogeneity observed in neuropsychiatric disorders. However, the majority of endophenotype studies were limited to our western counterparts, very little has been done and initiated by scholars in China's Mainland. In this paper, we urge the need to establish a potential central consortium for endophenotypes to study neuropsychiatric disorders in China's Mainland. In particular, we illustrate a potential example of neurological soft signs in following the steps for building the consortium. | CHAN Raymond C K | 2011 | Chinese Science Bulletin2011，56，32： | 3 |
| 17 | Effects of nanotopography on stem cell phenotypes显示文摘Stem cells are unspecialized cells that can self renew indefinitely and differentiate into several somatic cells given the correct environmental cues.In the stem cell niche,stem cell-extracellular matrix(ECM)interactions are crucial for different cellular functions,such as adhesion,proliferation,and differentiation.Recently, in addition to chemical surface modifications,the importance of nanometric scale surface topography and roughness of biomaterials has increasingly becoming recognized as a crucial factor for cell survival and host tissue acceptance in synthetic ECMs.This review describes the influence of nanotopography on stem cell phenotypes. | Rajeswari Ravichandran Clarisse CH Ng Casey K Chan Michael Raghunath Seeram Ramakrishna | 2009 | World Journal of Stem Cells2009，1，1： | 3 |
| 18 | Th1 cytokines promote T-cell binding to antigen-presenting cells via enhanced hyaluronan production and accumulation at the immune synapse显示文摘Hyaluronan(HA)production by dendritic cells(DCs)is known to promote antigen presentation and to augment T-cell activation and proliferation.We hypothesized that pericellular HA can function as intercellular‘glue’directly mediating T cell–DC binding.Using primary human cells,we observed HA-dependent binding between T cells and DCs,which was abrogated upon pre-treatment of the DCs with 4-methylumbelliferone(4-MU),an agent which blocks HA synthesis.Furthermore,T cells regulate HA production by DCs via T cell-derived cytokines in a T helper(Th)subset-specific manner,as demonstrated by the observation that cell-culture supernatants from Th1 but not Th2 clones promote HA production.Similar effects were seen upon the addition of exogenous Th1 cytokines,IL-2,interferon c(IFN-c)and tumor necrosis factor a(TNF-a).The critical factors which determined the extent of DC–T cell binding in this system were the nature of the pre-treatment the DCs received and their capacity to synthesize HA,as T-cell clones which were pre-treated with monensin,added to block cytokine secretion,bound equivalently irrespective of their Th subset.These data support the existence of a feedforward loop wherein T-cell cytokines influence DC production of HA,which in turn affects the extent of DC–T cell binding.We also document the presence of focal deposits of HA at the immune synapse between T-cells and APC and on dendritic processes thought to be important in antigen presentation.These data point to a pivotal role for HA in DC–T cell interactions at the IS. | Paul L Bollyky Stephen P Evanko Rebecca P Wu Susan Potter-Perigo S Alice Long Brian Kinsella Helena Reijonen Kelly Guebtner Brandon Teng Christina K Chan Kathy R Braun John A Gebe Gerald T Nepom Thomas N Wight | 2010 | Cellular & Molecular Immunology2010，7，3： | 3 |
| 19 | Novel role of STAT3 in microglia-dependent neuroinflammation after experimental subarachnoid haemorrhage显示文摘Background and purpose Signal transducer and activator of transcription 3(STAT3)may contribute to the proinflammation in the central nervous system diseases by modulating the microglial responses.Thus,this study was intended to investigate the effect of STAT3 on microglia-dependent neuroinflammation and functional outcome after experimental subarachnoid haemorrhage(SAH).Methods The SAH model was established by endovascular perforation in the mouse.Real-time PCR(RtPCR)and western blot were used to examine the dynamic STAT3 signalling pathway responses after SAH.To clarify the role of the STAT3 signalling pathway in the microglia-dependent neuroinflammation after SAH,the microglia-specific STAT3 knockout(KO)mice were generated by the Cre-LoxP system.The neurological functions were assessed by Catwalk and Morris water maze tests.Neuronal loss after SAH was determined by immunohistochemistry staining.Microglial polarisation status after STAT3 KO was then examined by RtPCR and immunofluorescence.Results The STAT3 and Janus kinase-signal transducer 2 activated immediately with the upregulation and phosphorylation after SAH.Downstream factors and related mediators altered dynamically and accordingly.Microglial STAT3 deletion ameliorated the neurological impairment and alleviated the early neuronal loss after SAH.To investigate the underlying mechanism,we examined the microglial reaction after STAT3 KO.STAT3 deletion reversed the increase of microglia after SAH.Loss of STAT3 triggered the early morphological changes of microglia and primed microglia from M1 to M2 polarisation.Functionally,microglial STAT3 deletion suppressed the SAH-induced proinflammation and promoted the anti-inflammation in the early phase.Conclusions STAT3 is closely related to the microglial polarisation transition and modulation of microglia-dependent neuroinflammation.Microglial STAT3 deletion improved neurological function and neuronal survival probably through promoting M2 polarisation and anti-inflammatory responses after SAH.STAT3 may serve as a promising therapeutic target to alleviate early brain injury after SAH. | Zhiyuan Vera Zheng Junfan Chen Hao Lyu Sin Yu Erica Lam Gang Lu Wai Yee Chan George K C Wong | 2022 | Stroke & Vascular Neurology2022，7，1： | 3 |
| 20 | 伴有浆细胞分化的套细胞淋巴瘤显示文摘 | Young K H Chan W C Fu K 黄文斌(摘译) | 2006 | 临床与实验病理学杂志2006，22，5： | 2 |
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