|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Bedside index for severity in acute pancreatitis:comparison with other scoring systems in predicting severity and organ failure显示文摘BACKGROUND:The early identification of severe acute pancreatitis is important for the management and for improving outcomes.The bedside index for severity in acute pancreatitis(BISAP)has been considered as an accurate method for risk stratification in patients with acute pancreatitis.This study aimed to evaluate the comparative usefulness of the BISAP.METHODS:We retrospectively analyzed 303 patients with acute pancreatitis diagnosed at our hospital from March 2007to December 2010.BISAP,APACHE-II,Ranson criteria,and CT severity index(CTSI)of all patients were calculated.We stratified the number of patiants with severe pancreatitis,pancreatic necrosis,and organ failure as well as the number of deaths by BISAP score.We used the area under the receiveroperating curve(AUC)to compare BISAP with other scoring systems,C-reactive protein(CRP),hematocrit,and body mass index(BMI)with regard to prediction of severe acute pancreatitis,necrosis,organ failure,and death.RESULTS:Of the 303 patiants,31(10.2%)were classified as having severe acute pancreatitis.Organ failure occurred in 23(7.6%)patients,pancreatic necrosis in 40(13.2%),and death in6(2.0%).A BISAP score of 2 was a statistically significant cutoff value for the diagnosis of severe acute pancreatitis,organ failure,and mortality.AUCs for BISAP predicting severe pancreatitis and death were 0.80 and 0.86,respectively,which were similar to those for APACHE-II(0.80,0.87)and Ranson criteria(0.74,0.74)and greater than AUCs for CTSI(0.67,0.42).The AUC for organ failure predicted by BISAP,APACHE-II,Ranson criteria,and CTSI was 0.93,0.95,0.84 and 0.57,respectively.AUCs for BISAP predicting severity,organ failure,and death were greater than those for CRP(0.69,0.80,0.72),hematocrit(0.45,0.35,0.14),and BMI(0.41,0.47,0.17).CONCLUSION:The BISAP predicts severity,death,and especially organ failure in acute pancreatitis as well as APACHE-II does and better than Ranson criteria,CTSI,CRP,hematocrit,and BMI. | Ji Young Park Tae Joo Jeon Tae Hwan Ha Jin Tae Hwang Dong Hyun Sinn Tae-Hoon Oh Won Chang Shin Won-Choong | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，6： | 33 |
| 2 | Long-term follow up of endoscopic resection for type 3 gastric NET显示文摘AIM:To clarify the short and long-term results and to prove the usefulness of endoscopic resection in type 3gastric neuroendocrine tumors(NETs).METHODS:Of the 119 type 3 gastric NETs diagnosed from January 1996 to September 2011,50 patients treated with endoscopic resection were enrolled in this study.For endoscopic resection,endoscopic mucosal resection(EMR)or endoscopic submucosal dissection(ESD)was used.Therapeutic efficacy,complications,and follow-up results were evaluated retrospectively.RESULTS:EMR was performed in 41 cases and ESD in 9 cases.Pathologically complete resection was performed in 40 cases(80.0%)and incomplete resection specimens were observed in 10 cases(7 vs 3 patients in the EMR vs ESD group,P=0.249).Upon analysis of the incomplete resection group,lateral or vertical margin invasion was found in six cases(14.6%)in the EMR group and in one case in the ESD group(11.1%).Lymphovascular invasions were observed in two cases(22.2%)in the ESD group and in one case(2.4%)in the EMR group(P=0.080).During the follow-up period(43.73;13-60 mo),there was no evidence of tumor recurrence in either the pathologically complete resection group or the incomplete resection group.No recurrence was reported during follow-up.In addition,no mortality was reported in either the complete resection group or the incomplete resection group for the duration of the follow-up period.CONCLUSION:Less than 2 cm sized confined submucosal layer type 3 gastric NET with no evidence of lymphovascular invasion,endoscopic treatment could be considered at initial treatment. | Yong Hwan Kwon Seong Woo Jeon Gwang Ha Kim Jin Il Kim Il-Kwun Chung Sam Ryong Jee Heung Up Kim Geom Seog Seo Gwang Ho Baik Kee Don Choi Jeong Seop Moon | 2013 | World Journal of Gastroenterology2013，19，46： | 14 |
| 3 | New magnifying endoscopic classification for superficial esophageal squamous cell carcinoma显示文摘AIM To assess the accuracy of a new magnifying endoscopy(ME)classification for predicting depth of invasion of superficial esophageal squamous cell carcinoma(SESCC).METHODS This study included a total of 70 lesions in 69 patients with SESCC who underwent ME with narrow-band imaging(ME-NBI)before resection from August 2010 to July 2016.Accuracy of ME-NBI for predicting depth of invasion of SESCC was analyzed by using a new ME classification proposed by the Japan Esophageal Society(JES),and interobserver agreement was assessed.RESULTS Overall accuracy of ME-NBI for estimating depth of invasion of SESCC was 78.6%.Sensitivity and specificity of type B1 for tumors limited to the epithelial layer(m1)or invading into the lamina propria(m2)were 71.4%and 100%,respectively.Sensitivity and specificity of type B2 for tumors invading into the muscularis mucosa(m3)or superficial submucosa(≤200μm,sm1)were94.4%and 73.1%,respectively,while those of type B3for tumors invading into the deep submucosa(>200μm,sm2)were 75.0%and 97.8%,respectively.Interobserver agreement was excellent(κ=0.86,95%CI:0.76-0.95).CONCLUSION The recently developed JES ME classification is useful for predicting depth of invasion of SESCC,with reliable interobserver agreement. | Su Jin Kim Gwang Ha Kim Moon Won Lee Hye Kyung Jeon Dong Hoon Baek Bong Eun Lee Geun Am Song | 2017 | World Journal of Gastroenterology2017，23，24： | 13 |
| 4 | Unveiling lymph node metastasis in early gastric cancer显示文摘With respect to gastric cancer treatment,improvements in endoscopic techniques and novel therapeutic modalities[such as endoscopic mucosal resection(EMR)and endoscopic submucosal dissection(ESD)]have been developed.Currently,EMR/ESD procedures are widely accepted treatment modalities for early gastric cancer(EGC).These procedures are most widely accepted in Asia,including in Korea and Japan.In the present era of endoscopic resection,accurate prediction of lymph node(LN)metastasis is a critical component of selecting suitable patients for EMR/ESD.Generally,indications for EMR/ESD are based on large Japanese datasets,which indicate that there is almost no risk of LN metastasis in the subgroup of EGC cases.However,there is some controversy among investigators regarding the validity of these criteria.Further,there are currently no accurate methods to predict LN metastasis in gastric cancer(for example,radiologic methods or methods based on molecular biomarkers).We recommend the use of a 2-step method for the management of early gastric cancer using endoscopic resection.The first step is the selection of suitable patients for endoscopic resection,based on endoscopic and histopathologic findings.After endoscopic resection,additional surgical intervention could be determined on the basis of a comprehensive review of the endoscopic mucosal resection/endoscopic submucosal dissection specimen,including lymphovascular tumor emboli,tumor size,histologic type,and depth of invasion.However,evaluation of clinical application data is essential for validating this recommendation.Moreover,gastroenterologists,surgeons,and pathologists should closely collaborate and communicate during these decisionmaking processes. | Nari Shin Tae-Yong Jeon Gwang Ha Kim Do Youn Park | 2014 | World Journal of Gastroenterology2014，20，18： | 10 |
| 5 | Risk of lymph node metastasis in mixed-type early gastric cancer determined by the extent of the poorly differentiated component显示文摘AIM: To predict the rate of lymph node(LN) metastasis in diffuse- and mixed-type early gastric cancers(EGC) for guidelines of the treatment.METHODS: We reviewed 550 cases of EGC withdiffuse- and mixed-type histology. We investigated the clinicopathological factors and histopathological components that influence the probability of LN metastasis, including sex, age, site, gross type, presence of ulceration, tumour size, depth of invasion, perineural invasion, lymphovascular invasion, and LN metastasis status. We reviewed all slides and estimated the proportions of each tumour component; pure diffuse type, mixed-predominantly diffuse type(diffuse > intestinal type), mixed-predominantly intestinal type(intestinal > diffuse type), and mixed diffuse = intestinal type. We calculated the extents of the respective components.RESULTS: LN metastasis was observed in 12.9%(71/550) of early gastric cancers cases [15/288 mucosal EGCs(5.2%) and 56/262 submucosal EGCs(21.4%)]. Of 550 cases, 302 were diffuse-type and 248 were mixed-type EGCs. Of 248 mixed-type EGCs, 163 were mixed-predominantly diffuse type, 82 were mixed-predominantly intestinal type, and 3 were mixed diffuse = intestinal type. Mixed-type cases with predominantly diffuse type histology showed a higher frequency of LN metastasis(20.2%) than cases of pure diffuse type(9.3%) and predominantly intestinal type(12.2%) histology. We measured the dimensions of each component(intestinal and diffuse type) to determine the association of the extent of each component with LN metastasis in mixed-type gastric carcinoma. The total tumour size and the extent of poorly differentiated components was associated with LN metastasis, while that of signet ring cell components was not.CONCLUSION: We recommend careful identification and quantitative evaluation of mixed-type early gastric cancer components after endoscopic resection to determine the intensity of the treatment. | Chung-Su Hwang Sangjeong Ahn Bong-Eun Lee So-Jeong Lee Ahrong Kim Chang In Choi Dae Hwan Kim Tae-Yong Jeon Gwang Ha Kim Geum Am Song Do Youn Park | 2016 | World Journal of Gastroenterology2016，22，15： | 8 |
| 6 | Glehnia fittoralis Extract Promotes Neurogenesis in the Hippocampal Dentate Gyrus of the Adult Mouse through Increasing Expressions of Brain-Derived Neurotrophic Factor and Tropomyosin-Related Kinase B显示文摘 | Joon Ha Park Bich Na Shin Ji Hyeon Ahn Jeong Hwi Cho Tae-Kyeong Lee Jae-Chul Lee Yong Hwan Jeon II Jun Kang Ki-Yeon Yoo In Koo Hwang Choong Hyun Lee Yoo Hun Noh Sung-Su Kim Moo-Ho Won Jong Dai Kim | 2018 | Chinese Medical Journal2018，，6： | 6 |
| 7 | Chicken soup for teaching and learning ESD显示文摘Endoscopic submucosal dissection(ESD) is becoming a popular procedure for the diagnosis and treatment of superficial mucosal lesions,and has the advantage of en bloc resection which yields a higher complete resection and remission rate compared to endoscopic mucosal resection(EMR).However,the learning process of this advanced endoscopic procedure requires a lengthy training period and considerable experience to be proficient.A well framed training protocol which is safe,effective,easily reproducible and cost-effective is desirable to teach ESD.In addition,the training course may need to be tailored around settings such as ethnicity,culture,workload,and disease incidence.In Asian countries with a large volume of early gastric lesions which need endoscopic treatment,endoscopists would be able to learn ESD expanding their skills from EMR to ESD under the supervision of experts.Whereas,in Western countries due to the low incidence of superficial gastric tumors,trials have utilized simulator models to improve learning.In Korea,the Korean Society of Gastrointestinal Endoscopy(KSGE) is playing an important role in training many gastroenterologists who have shown an interest in performing ESD by providing an annual live demonstration and a nationwide tutoring program.The purpose of this article is to introduce our ESD tutoring experience,review the published papers related to this topic,and propose several suggestions for future directions in teaching and learning ESD. | Eun Young Kim Seong Woo Jeon Gwang Ha Kim | 2011 | World Journal of Gastroenterology2011，17，21： | 3 |
| 8 | Benidipine has effects similar to losartan on the central blood pressure and arterial stiffness in mild to moderate essential hypertension显示文摘 | Sang-Hyun Ihm Hui-Kyung Jeon Shung Chull Chae Do-Sun Lim Kee-Sik Kim Dong-Ju Choi Jong-Won Ha Dong-Soo Kim Kye Hun Kim Myeong-Chan Cho Sang Hong Baek | 2013 | Chinese Medical Journal2013，，11： | 3 |
| 9 | Mucin Expression in Gastric Cancer: Reappraisal of Its Clinicopathologic and Prognostic Significance显示文摘 | Kim Dae Hwan Shin Nari Kim Gwang Ha Song Geum Am Jeon Tae-Yong Kim Dong-Heon Lauwers Gregory Y Park Do Youn | 2013 | Archives of Pathology & Laboratory Medicine2013，，8： | 2 |
| 10 | Analysis of a Triose Phosphate/Phosphate Translocator- Deficient Mutant Reveals a Limited Capacity for Starch Synthesis in Rice Leaves显示文摘Dear Editor, During CO2 assimilation,the reductive pentose phosphate cycle generates triose phosphates (triose-P) at the expense of ATP and NADPH generated by photosynthetic light reactions.Triose-P is retained within chloroplasts to either regenerate the CO2 acceptor ribulose-1,5-bisphosphate or to feed into transitory starch synthesis.Alternatively,triose-P can be exported into the cytosol to produce sucrose.To maintain optimum rates of photosynthesis,the rate of triose-P export from the chloroplast stroma to the cytosol is necessarily adjusted to the demands for photoassimilate export.The triose-P/phosphate (Pi) transiocator (TPT) mediates the export of stromal triose-P into the cytosol in a counter exchange for cytosolic Pi.The rate of triose-P export is primarily regulated by the availability of Pi liberated by cytosolic sucrose synthesis.When sucrose synthesis slows down during the day,the restriction in Pi availability reduces TPT transport activity and redirects assimilated carbon into transitory starch synthesis in the chloroplast (B(o)rnke and Sonnewald,2011). | Sang-Kyu Lee Joon-Seob Eom Lars M. Voll Christian M. Prasch Youn-ll Park Tae-Ryong Hahn Sun-Hwa Ha GynheungAn Jong-Seong Jeon | 2014 | Molecular Plant2014，7，11： | 2 |
| 11 | Validation of Circulating miRNA Biomarkers for Predicting Lymph Node Metastasis in Gastric Cancer显示文摘 | Shine Young Kim Tae Yong Jeon Chang In Choi Dae Hwan Kim Dong Heon Kim Gwang Ha Kim Dong Yup Ryu Bong Eun Lee Hyung Hoi Kim | 2013 | The Journal of Molecular Diagnostics2013，，： | 2 |
| 12 | Spectrum of mucin-producing neoplastic conditions of the abdomen and pelvis:Cross-sectional imaging evaluation显示文摘Various mucin-producing neoplasms originate in different abdominal and pelvic organs.Mucinous neoplasms differ from non-mucinous neoplasms because of the differences in clinical outcome and imaging appearance.Mucinous carcinoma,in which at least 50%of the tumor is composed of large pools of extracellular mucin and columns of malignant cells,is associated with a worse prognosis.Signet ring cell carcinoma is characterized by large intracytoplasmic mucin vacuoles that expand in the malignant cells with the nucleus displaced to the periphery.Its prognosis is also generally poor.In contrast,intraductal papillary mucinous neoplasm of the bile duct and pancreas,which is characterized by proliferation of ductal epithelium and variable mucin production,has a better prognosis than other malignancies in the pancreaticobiliary tree.Imaging modalities play a critical role in differentiating mucinous from non-mucinous neoplasms.Due to high water content,mucin has a similar appearance to water on ultrasound(US) ,computed tomography(CT) ,and magnetic resonance imaging,except when thick and proteinaceous,and then it tends to be hypoechoic with fine internal echoes or have complex echogenicity on US,hyperdense on CT,and hyperintense on T1and hypointense on T2-weighted images,compared to water.Therefore,knowledge of characteristic mucin imaging features is helpful to diagnose various mucinproducing neoplastic conditions and to facilitate appropriate treatment. | Nam Kyung Lee Suk Kim Hyun Sung Kim Tae Yong Jeon Gwang Ha Kim Dong Uk Kim Do Youn Park Tae Un Kim Dae Hwan Kang | 2011 | World Journal of Gastroenterology2011，17，43： | 2 |
| 13 | Functional characteristics of two BKCa channel variants differentially expressed in rat brain tissues显示文摘 | Ha TS Jeong SY Cho SW Jeon HK Roh GS Choi WS Park CS | | 0，，： | 1 |
| 14 | Mechanisms underlying TGFbeta 1-induced expression of VEGF and Flk-1 in mouse macrophages and their implications for angiogenesis显示文摘 | Jeon SH Chae BC Kim HA | 2007 | J Leukoc Biol2007，81，2： | 1 |
| 15 | A Generalized Approach for the Acceleration and Deceleration of Industrial Robots and CNC Machine Tools显示文摘 | Jeon J W Ha Y Y | 2000 | IEEE Transactions on Industrial Electronics2000，47，1： | 1 |
| 16 | Therapeutic effect of DNA vaccines combined with chemotherapy in a latent infection model after aerosol infection of mice with Mycobacterium tuberculosis显示文摘 | HA S J JEON B Y KIM S C | 2003 | Gene Therapy2003，10，18： | 1 |
| 17 | Serum growth arrest-specific protein 6 levels are a reliable biomarker of disease activity in systemic lupus erythematosus显示文摘 | Kim HA Nam JY Jeon JY | 2013 | J Clin Immunol2013，33，： | 1 |
| 18 | C-reactive protein is a more sensitive and specific marker for diagnosing bacterial infections in systemic lupus erythematosus compared to S100AS/A9 and procalcitonin显示文摘 | Kim HA Jeon JY An JM | | 0，，04： | 1 |
| 19 | Suppression of Oxidative Stress of Modified Gongjin-Dan (WSY^1075) in Detrusor Underactivity Rat Model Bladder Outlet Induced by Obstruction显示文摘Objective: To investigate the anti-oxidative stress and preventive effect of modified Gongjin-dan(WSY-1075) in a detrusor underactivity rat model. Methods: Rats were randomly allocated to three groups: shamoperated(control), bladder outlet obstruction-induced detrusor underactivity(BOO-DU), and BOO-DU with WSY-1075(WSY) groups. WSY-1075 was oral y administrated to rats 200 mg daily for 2 weeks prior to the operation and 4 weeks after the operation. Bladder outlet obstruction was surgical y induced in rats by ligation around the urethra avoiding total obstruction. Cystometrography was conducted on rats in each group for examination of bladders. Results: Compared with the control group, bladder outlet obstruction led to a significant increase in oxidative stress with consequent changes to molecular composition, and decrease in maximal detrusor pressure(P<0.05). WSY-1075 treatment significantly suppressed oxidative stress and prevented degenerative and dysfunctional changes in bladder, as compared with BOO-DU group(P<0.05). Conclusion: WSY-1075 had beneficial effect on prevention of BOO-DU. | Jin-Woo Jung Seung Hwan Jeon Woong Jin Bae Su Jin Kim Mun Su Chung Byung II Yoon Sae Woong Choi U Syn Ha Sung Yeoun Hwang Sae Woong Kim | 2018 | Chinese Journal of Integrative Medicine2018，24，9： | 1 |
| 20 | Mechanisms underlying TGF - be- tal -induced expression of VEGF and Flk - 1 in mouse macrophages and their implications for angiogenesis 显示文摘 | Jeon SH Chae BC Kim HA | 2007 | J Leukoc Biol2007，81，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员