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| 1 | Metadoxine improves the three- and six-month survival rates in patients with severe alcoholic hepatitis显示文摘AIM:To evaluate the impact of metadoxine(MTD) on the 3- and 6-mo survival of patients with severe alcoholic hepatitis(AH).METHODS:This study was an open-label clinical trial,performed at the'Hospital General de México,Dr.Eduardo Liceaga'.We randomized 135 patients who met the criteria for severe AH into the following groups:35 patients received prednisone(PDN)40 mg/d,35patients received PDN+MTD 500 mg three times daily,33 patients received pentoxifylline(PTX)400 mg three times daily,and 32 patients received PTX+MTD 500 mg three times daily.The duration of the treatment for all of the groups was 30 d.RESULTS:In the groups treated with the MTD,thesurvival rate was higher at 3 mo(PTX+MTD 59.4%vs PTX 33.3%,P=0.04;PDN+MTD 68.6%vs PDN20%,P=0.0001)and at 6 mo(PTX+MTD 50%vs PTX18.2%,P=0.01;PDN+MTD 48.6%vs PDN 20%,P=0.003)than in the groups not treated with MTD.A relapse in alcohol intake was the primary independent factor predicting mortality at 6 mo.The patients receiving MTD maintained greater abstinence than those who did not receive it(74.5%vs 59.4%,P=0.02).CONCLUSION:MTD improves the 3-and 6-mo survival rates in patients with severe AH.Alcohol abstinence is a key factor for survival in these patients.The patients who received the combination therapy with MTD were more likely to maintain abstinence than those who received monotherapy with either PDN or PTX. | Fátima Higuera-de la Tijera Alfredo I Servín-Caamano Aurora E Serralde-Zúniga Javier Cruz-Herrera Eduardo Pérez-Torres Juan M Abdo-Francis Francisco Salas-Gordillo JoséL Pérez-Hernández | 2015 | World Journal of Gastroenterology2015，21，16： | 8 |
| 2 | Mapping aboveground biomass by integrating geospatial and forest inventory data through a k-nearest neighbor strategy in North Central Mexico显示文摘As climate change negotiations progress,monitoring biomass and carbon stocks is becoming an important part of the current forest research.Therefore,national governments are interested in developing forest-monitoring strategies using geospatial technology.Among statistical methods for mapping biomass,there is a nonparametric approach called k-nearest neighbor(kNN).We compared four variations of distance metrics of the kNN for the spatially-explicit estimation of aboveground biomass in a portion of the Mexican north border of the intertropical zone.Satellite derived,climatic,and topographic predictor variables were combined with the Mexican National Forest Inventory(NFI)data to accomplish the purpose.Performance of distance metrics applied into the kNN algorithm was evaluated using a cross validation leave-one-out technique.The results indicate that the Most Similar Neighbor(MSN)approach maximizes the correlation between predictor and response variables(r=0.9).Our results are in agreement with those reported in the literature.These findings confirm the predictive potential of the MSN approach for mapping forest variables at pixel level under the policy of Reducing Emission from Deforestation and Forest Degradation(REDD+). | Carlos A AGUIRRE-SALADO Eduardo J TREVIO-GARZA Oscar A AGUIRRE-CALDERóN Javier JIMNEZ-PREZ Marco A GONZLEZ-TAGLE José R VALDZ-LAZALDE Guillermo SNCHEZ-DíAZ Reija HAAPANEN Alejandro I AGUIRRE-SALADO Liliana MIRANDA-ARAGóN | 2014 | Journal of Arid Land2014，6，1： | 3 |
| 3 | Barredo, etc, Monitoring landslides from optical remotely sensed imagery, eomorphology显示文摘 | Javier Hervás José I | 2003 | 54(2003)63-752003，54，： | 1 |
| 4 | Numerical investigation of NOx emissions from a tangentially-fired utility boiler under conventional and overfire air operation显示文摘 | LUIS I D CRISTOBAL C JAVIER P | 2007 | Fuel2007，87，7： | 1 |
| 5 | Wheat fiber as a functional ingredient in restructured fish products显示文摘 | SANCHEZ-ALONSO I HAJI-MALEKI R JAVIER BORDERIAS A | 2007 | Food Chemistry2007，100，3： | 1 |
| 6 | Development and characterization of composite edible films based on whey protein isolate and mesquite gum显示文摘 | Javier O Mayra F V Ruth P I | 2009 | Journal of Food Engineering2009，92，1： | 1 |
| 7 | Inhibition of angiotensin converting enzyme (ACE) activity by flavan - 3 - ols and procyanidins 显示文摘 | Lucas Actis -Goretta Javier I Ottaviani Carl L Keen | 2003 | FEBS let- ters2003，555，3： | 1 |
| 8 | Recycled concrete made with different natural coarse aggregates exposed to high temperature 显示文摘 | Zega Claudio Javier Maio Angel Antonio I)i | 2009 | Construction and Building Materials2009，23，5： | 1 |
| 9 | Is plasma 25(OH) D related to adipokines, inflammatory cytokines and insulin resistance in both a healthy and morbidly obese population?显示文摘 | Núria Vilarrasa Joan Vendrell Javier Maravall I?aki Elío Esther Solano Patricia San José Isabel García Núria Virgili Juan Soler José Manuel Gómez | 2010 | Endocrine2010，，2： | 1 |
| 10 | Hyaluronic acid production by Streptococcus zooepidemicus in rnarine by-products media from mussel processing wastewaters and tuna peptone viscera显示文摘 | José A Vázquez María I Montemayor Javier Fraguas | | 0，，09： | 1 |
| 11 | Early effects of rood ulating nuclear factor-kB activation on traumatic spinal cord in jury in rats 显示文摘 | Octavio J C Javier C Antonio I | 2005 | Ann NY Acad Sci2005，1053，7： | 1 |
| 12 | Intergenerational Income Mobility ina Less-Developed,High-Inequality Context:The Caseof Chile显示文摘 | I Javier Nunez Leslie Miranda | | 0，，： | 1 |
| 13 | Chilling of drought-hardened and no-hardened plants of different chilling-sensitive maize lineschanges in water relations and ABA contents显示文摘 | Javier P D Jose I J Manuel S D | 1997 | Plant Sci1997，122，： | 1 |
| 14 | Monitoring landslides from optical remotely sensed imagery: the case history of Tessina landslide, Italy显示文摘 | Javier Hervás José I Barredo Paul L Rosin Alessandro Pasuto Franco Mantovani Sandro Silvano | 2003 | Geomorphology2003，，1： | 1 |
| 15 | Effect of methyl ,jasmonate on properties of intact tomato fruit mo- nitored with destructive and nondestructive tests 显示文摘 | Baltazar A Javier E L Torres I R | 2007 | Journal of Food Engineering2007，，80： | 1 |
| 16 | Xylanase production by a new alkalitolerant isolate of Bacillus显示文摘 | L'opez C Blanco A Javier Pastor F I | 1998 | Biotechnology Letters1998，20，3： | 1 |
| 17 | Chilling of drought-hardened and no-hardened plants of different chilling-sensitive maize lines-changes in water relations and ABA content显示文摘 | Javier P D Jose I J Manuel S D | 1997 | Plant Sciences1997，122，： | 1 |
| 18 | Inhibition of angiotensin converting enzyme activity by flavanol-rich foods显示文摘 | Lucas A G Javier I O Cesar G F | 2006 | Journal of Agricultural and Food Chemistry2006，54，1： | 1 |
| 19 | Tadalafil Enhances the Inhibitory Effects of Tamsulosin on Neurogenic Contractions of Human Prostate and Bladder Neck显示文摘 | Javier Angulo Pedro Cuevas Argentina Fernández José M. La Fuente Antonio Allona Ignacio Moncada I?igo Sáenz de Tejada | 2012 | The Journal of Sexual Medicine2012，，9： | 1 |
| 20 | Auction design in day-ahead electricity markets显示文摘 | Javier C Oscar C Jose I F | 2001 | IEEE Transactions on Power Systems2001，16，1： | 1 |
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