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| 1 | Open versus laparoscopic surgery for mid or low rectal cancer after neoadjuvant chemoradiotherapy (COREAN trial): short-term outcomes of an open-label randomised controlled trial显示文摘 | Sung-Bum Kang Ji Won Park Seung-Yong Jeong Byung Ho Nam Hyo Seong Choi Duck-Woo Kim Seok-Byung Lim Taek-Gu Lee Dae Yong Kim Jae-Sung Kim Hee Jin Chang Hye-Seung Lee Sun Young Kim Kyung Hae Jung Yong Sang Hong Jee Hyun Kim Dae Kyung Sohn Dae-Hyun Kim Jae H | 2010 | Lancet Oncology2010，，7： | 5 |
| 2 | Features of extrahepatic metastasis after radiofrequency ablation for hepatocellular carcinoma显示文摘BACKGROUND Extrahepatic metastasis(EHM)of hepatocellular carcinoma(HCC)is associated with poor outcomes.However,the clinical features and risk factors of EHM of HCC after radiofrequency ablation(RFA)remain unclear.AIM To elucidate the characteristics and risk factors of EHM after RFA for HCC.METHODS From January 2008 to December 2017,we retrospectively enrolled 661 patients who underwent RFA as first-line treatment for HCC at 2 tertiary hospitals.The inclusion criteria were age≥18 years,a diagnosis of HCC,and treatment-naivety.Abdominal computed tomography(CT)or magnetic resonance imaging(MRI)and alpha-fetoprotein measurements were routinely performed at 1 mo after RFA and followed-up at intervals of 3-6 mo.Univariate analyses were performed using the chi-squared test or Student’s t-test,and univariate and multivariate analyses were performed via logistic regression,as appropriate.RESULTS EHM was diagnosed in 44 patients(6.7%)during a median follow-up period of 1204 days.The 10-year cumulative rate of HCC recurrence and EHM was 92.7%and 33.7%,respectively.Initial recurrence was most often intrahepatic,and the rate of extrahepatic recurrence at initial recurrence was only 1.2%.The median time to the diagnosis of EHM was 2.68 years,and 68.2%of patients developed EHM within 2 years of the first recurrence,regardless of recurrence-free survival and 75.0%of patients developed EHM within 5 years after first recurrence.EHM was mostly diagnosed via abdominal CT/MRI in 33(75.0%)and 38 of 44 patients(86.4%)with EHM had either positive abdominal CT scan results or serum AFP level elevation.In multivariate analysis,recurrence-free survival<2 years,ablation zone/tumor size<2,and alpha-fetoprotein level>400 IU/mL were associated with a high EHM risk.CONCLUSION EHM occurs following multiple intrahepatic recurrences after RFA and combined contrast-enhanced abdominal CT and serum AFP were useful for surveillance.Patients especially with high-risk factors require close follow-up for EHM. | Jae H Yoon Young J Goo Chae-Jun Lim Sung K Choi Sung B Cho Sang S Shin Chung H Jun | 2020 | World Journal of Gastroenterology2020，26，32： | 3 |
| 3 | Combination of corticosteroids and 5-aminosalicylates or corticosteroids alone for patients with moderate-severe active ulcerative colitis:A global survey of physicians'practice显示文摘AIM To examine treatment decisions of gastroenterologists regarding the choice of prescribing 5-aminosalycilates(5ASA) with corticosteroids(CS) versus corticosteroids alone for patients with active ulcerative colitis(UC). METHODS A cross-sectional questionnaire exploring physicians' attitude toward 5ASA + CS combination therapy vs CS alone was developed and validated. The questionnaire was distributed to gastroenterology experts in twelve countries in five continents. Respondents' agreement with stated treatment choices were assessed by standardized Likert scale. Background professional characteristics of respondents were analyzed for correlation with responses. RESULTS Six hundred and sixty-four questionnaires were distributed and 349 received(52.6% response rate). Of 340 eligible respondents, 221(65%) would continue 5ASA in a patient hospitalized for intravenous CS treatment due to a moderate-severe UC flare, while 108(32%) would stop the 5ASA(P < 0.001), and 11(3%) are undecided. Similarly, 62% would continue 5ASA in an out-patient starting oral CS. However, only 140/340(41%) would proactively start 5ASA in a hospitalized patient not receiving 5ASA before admission. Most(94%) physicians consider the safety profile of 5ASA as very good. Only 52% consider them inexpensive, 35% perceive them to be expensive and 12% are undecided. On multi-variable analysis, less years of practice and perception of a plausible additive mechanistic effect of 5ASA + CS were positively associated with the decision to continue 5ASA with CS. CONCLUSION Despite the absence of data supporting its benefit, most gastroenterologists endorse combination of 5ASA + CS for patients with active moderate-to-severe UC. Randomized controlled trials are needed to assess if 5ASA confer any benefit for these patients. | Shomron Ben-Horin Jane M Andrews Konstantinos H Katsanos Florian Rieder Flavio Steinwurz Konstantinos Karmiris Jae Hee Cheon Gordon William Moran Monica Cesarini Christian D Stone Doron Schwartz Marijana Protic Xavier Roblin Giulia Roda Min-Hu Chen Ofir Har-Noy Charles N Bernstein | 2017 | World Journal of Gastroenterology2017，23，16： | 3 |
| 4 | Fine Root Biomass, Production and Turnover in a Fertilized Larixin leptolepis Plantation in Central Korea显示文摘 | Son Y Jae H H | 2003 | Ecological Research2003，18，： | 1 |
| 5 | Critical velocity and burning rate in pool fire during longitudinal ventilation显示文摘 | JAE S R HING S R DONG H K | 2007 | Tunnelling and Underground Space Technology2007，，22： | 1 |
| 6 | Transduction of human catalase mediated by an HIV-1 tat protein basic domain and arginine-rich peptides into mammalian cells 显示文摘 | LI H J JAE H B WON S E | 2001 | Free Radical Biology & Medicine2001，31，11： | 1 |
| 7 | Enhancement of optical re- mote sensing images by subband-decomposed multi- scale Retinex with hybrid intensity transfer Function 显示文摘 | Jae H J Sung D K Jong B | 2011 | IEEE Geoscience and Remote Sensing Letters2011，8，5： | 1 |
| 8 | A study on die wear model considering thermal softening ( Ⅱ ): Application of the suggested wear model显示文摘 | Kang J H Park I W Jae J S | 1999 | Journal of Materials Processing Technology1999，94，23： | 1 |
| 9 | Targeted delivery of low moleculardrugs using chitosan and its derivatives显示文摘 | Jae H P Gurusamy S Kwangmeyung K | 2010 | Advanced Drug Delivery Revie-ws2010，62，： | 1 |
| 10 | Effect of apple pomace on the liver damage in bromobenzene-treated rats显示文摘 | Shin K C Kyeok K Jae H L | 2001 | Food Science and Biotechnology2001，10，3： | 1 |
| 11 | Evidence that pro- tease-activated receptor-2 mediate trypsin-induced reversal of stellation in cultured rat astrocytes 显示文摘 | Gyu H P Jae R R Shin Ch Y | 2006 | Neuroscience Research2006，，54： | 1 |
| 12 | Atomic scale investigation on the distribution of boron in medium carbon steels by atom probe tomography and EELS显示文摘 | JAE B S GIL H G NAMS L | 2010 | Ultramicroscopy2010，110，7： | 1 |
| 13 | Laser clad Ni-base alloy added nano- and micron-size CeO2 composites显示文摘 | Zhang S H Li M X Tong Yul Cho Jae Hong Yoon Chan Gyu Lee and He Y Z | 2008 | Optics & Laser Technology2008，40，5： | 1 |
| 14 | Identification of Epithelial Cell Adhesion Molecule Autoantibody inpatients with Ovarian Cancer显示文摘 | Jae K Dorethee H Kwong K | 2003 | Clinical Cancer Research2003，9，： | 1 |
| 15 | Transcatheter arterial embolization of nonvariceal upper gastrointestinal bleeding with N-butyl cyanoacrylate显示文摘 | Jae H J Chung JW Jung AY | 2007 | Korean J Radiol2007，8，： | 1 |
| 16 | MR imaging of hypertropic Cardiomyopathy显示文摘 | Kin Ym Chung JW | 1992 | Radiology1992，185，： | 1 |
| 17 | Generalization of linear discriminant analysis using Lp-norm 显示文摘 | JAE H O NOJUN K | 2013 | Pattern Recognition Letters2013，34，6： | 1 |
| 18 | Current status and per- spectives of biopharmaceutical drugs 显示文摘 | JAE K R HYO S K DOO H N | 2012 | Biotechnology and Bioprocess Engineering2012，17，： | 1 |
| 19 | The relationship between cytokines and HPV - 16 ,HPV - 16 E6,E7 and high - risk HPV viral load in the uterine cervix显示文摘 | Seung H S Jae K L O ye S S | 2007 | Gynecol O ncol2007，104，3： | 1 |
| 20 | An Overview of Peak-to-average Power Ratio Reduction Techniques for Multicarrier Transmission显示文摘 | SEUNG H H JAE H L | 2005 | IEEE Wireless Communications2005，12，02： | 1 |
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