|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Mnk kinase pathway: Cellular functions and biological outcomes显示文摘The mitogen-activated protein kinase(MAPK) interacting protein kinases 1 and 2(Mnk1 and Mnk2) play important roles in controlling signals involved in mRNA translation. In addition to the MAPKs(p38 or Erk), multiple studies suggest that the Mnk kinases can be regulated by other known kinases such as Pak2 and/or other unidentified kinases by phosphorylation of residues distinct from the sites phosphorylated by the MAPKs. Several studies have established multiple Mnk protein targets, including PSF, heterogenous nuclear ribonucleoprotein A1, Sprouty 2 and have lead to the identification of distinct biological functions and substrate specificity for the Mnk kinases. In this review we discuss the pathways regulating the Mnk kinases, their known substrates as well as the functional consequences of engagement of pathways controlled by Mnk kinases. These kinases play an important role in mRNA translation via their regulation of eukaryotic initiation factor 4E(eIF4E) and their functions have important implications in tumor biology as well as the regulation of drug resistance to anti-oncogenic therapies. Other studies have identified a role for the Mnk kinases in cap-independent mRNA translation, suggesting that the Mnk kinases can exert important functional effects independently of the phosphorylation of eIF4 E. The role of Mnk kinases in inflammation and inflammationinduced malignancies is also discussed. | Sonali Joshi Leonidas C Platanias | 2014 | World Journal of Biological Chemistry2014，5，3： | 16 |
| 2 | 印度农业推广改革现状:战略重点和政策选择显示文摘独立以来,虽然印度农业推广经历了翻天覆地的变化,但是小农农民和其他弱势群体仍未参与到公共推广体系之中。许多组织性能问题妨碍了公共推广体系的效率和效果。这些问题包括人员的匮乏,较低的合作伙伴关系以及继续自上而下的线性推广方式。本文回顾了印度农业推广改革的现状,并基于比哈尔、喜马偕尔邦、马哈拉施特拉邦和泰米尔纳德邦等4个邦的实地调研,分析并进一步细化了当前的改革进程,在此基础上,提出了促进农业公共推广体系有序发展和运行的优先政策和战略选择。 | Suresh C Babu P K Joshi Claire J.Glendenning Kwadwo Asenso-Okyere Rasheed Sulaiman V 蔡彦虹(翻译) | 2017 | 世界农业2017，，7： | 2 |
| 3 | Change in pore size distribution due to consolidation of clays显示文摘 | Griffiths F J Joshi R C | 1989 | Gèotechnique1989，39，1： | 2 |
| 4 | 基于离散滑模控制的通信网络拥塞控制(英文)显示文摘最近30年来,离散滑模控制(DSMC)被加以研究.在现有离散滑模控制的文献中,不但有完善的理论,并且有应用的实例.计算机通信网络(涵盖有线和无线情形)的发展给控制专家提出了具有挑战性的问题.此类系统的响应很快,因此要求控制器必须能快速反应.同时,此类系统中的数据包和路由采用固有的切换方式.因此,在该网络系统中采用与其固有切换类似的滑动模态控制成为一个有趣的问题.本文应用离散滑模控制方法来解决通信网络的拥塞控制问题.在过去几年中,许多反馈控制方法被用来解决通信网络的许多问题,如流量控制,拥塞控制和功率控制.本文提出了一种新的应用滑动模态控制来实现通信网络拥塞控制的方法.由于计算机通信网络处理的是数字数据且在本质上是离散的,因此其是一类离散时间系统,因而可应用离散滑模控制.在该系统中,比特率保持恒定不变,通过调整缓冲区的长度来控制拥塞.出于模拟与分析的目的,缓冲区的最大长度被设为250bit.本文展示了离散滑模控制能够实现通讯网络不同特性的控制. | Rutvij C Joshi Vishvjit K Thakar | 2012 | 中国科学技术大学学报2012，42，7： | 2 |
| 5 | Structural and electrical characteristics of rapid thermally processed ferroelectric Bi4Ti3O12 thin films prepared by metalorganic solution deposition technique显示文摘 | JOSHI P C DESU S B | 1996 | J Appl Phys1996，80，4： | 2 |
| 6 | Xanthanolides from Xanthium indicum显示文摘 | Bohlmann F Singh P Joshi K C | 1982 | Phytochemistry1982，21，6： | 1 |
| 7 | Organization Knowledge Resources显示文摘 | Holsapple C W Joshi K D | 2001 | Decision Support Systems2001，，31： | 1 |
| 8 | A new species of Rhizoucor显示文摘 | Joshi M C | 1982 | Sydowia1982，35，： | 1 |
| 9 | Genomics of cellulose biosynthesis in poplars 显示文摘 | Joshi C P Bhandari S Ranjan P | 2004 | New Phytol2004，164，： | 1 |
| 10 | Building many-core processor to DRAM networks with monolithic CMOS silicon photonics显示文摘 | Batten C Joshi A Orcutt J | 2009 | IEEE Micro2009，29，4： | 1 |
| 11 | Facile synthesis noval fluorine containning pyrazole based thiazole derivatives and evaluation of antimicrobial activity 显示文摘 | Desai N C Joshi K M Rajpara H V | 2012 | Journal of Fluorine Chemistry2012，142，： | 1 |
| 12 | Image restoration by ma-tching gradient distributions显示文摘 | Cho T S Zitnick C L Joshi N | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，4： | 1 |
| 13 | Reproducible,ultra highthroughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates显示文摘 | Ungrin MD Joshi C Nica A | 2008 | PLoS One2008，3，2： | 1 |
| 14 | An investigation of factors that influence the management of knowledge in organizations 显示文摘 | Holsapple C W Joshi K D | 2000 | Jouma of Strategic Information Systems2000，9，23： | 1 |
| 15 | The influence of Mg doping on the materials properties of Ba1-xSrxTiO3 thin films for tunable device applications 显示文摘 | Cole M W Joshi P C Ervin M H | 2000 | Thin Solid Films2000，374，： | 1 |
| 16 | The formation of ultrasonic bonds between metals显示文摘 | Joshi K C | 1971 | Welding1971，50，： | 1 |
| 17 | Solid state interfacial reactions of Ti3Al with Si3N4 and SiC显示文摘 | Chou T C Joshi A | 1992 | J Mater Res1992，7，： | 1 |
| 18 | Change in pore size distribution due to consolidation of clays 显示文摘 | Grifiths J Joshi R C | 1989 | Geotechnique1989，39，1： | 1 |
| 19 | Interaction of the primary anti-symmetric Lamb mode (A0) with sym- metric delaminations: numerical and experimental studies 显示文摘 | Ramadas C Balasubramaniam K Joshi M | 2009 | Smart Materials and Structures2009，18，8： | 1 |
| 20 | Preparation of Ce3+ -activated UV-emitting fluoride phosphors显示文摘 | Belsare P D Joshi C P Moharil S V | 2009 | RadiationEffects & Defects in Solids2009，164，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员