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| 1 | 光动力疗法治疗非小细胞肺癌显示文摘光动力疗法被越来越多地应用于治疗胸部恶性肿瘤。对于早期非小细胞肺癌(如支气管腔内肺癌)、X线检查阴性或同时性原发癌,光动疗法可作为主要治疗手段进行腔内根治性治疗。作为单一根治疗法,光动力疗法是治疗支气管镜可见≤1 cm且无软骨外浸润的肺部肿瘤的最有效方法。对于晚期非小细胞癌患者,光动力治疗可以作为综合根治疗法的一部分,用于减轻阻塞性支气管内病变,增加可手术性或缩小所需手术范围。本文对现有发表的应用光动力疗法治疗至少10例以上非小细胞肺癌病例的研究文献进行综述,提出了光动力疗法应用的治疗建议并进行了总结。 | Charles B Simone II Joseph S Friedberg Eli Glatstein James P Stevenson Daniel H Sterman Stephen M Hahn Keith A Cengel 袁光金 李金銮 朱宇熹 凌扬 | 2013 | 国际病理科学与临床杂志2013，33，3： | 3 |
| 2 | The treatment of traumatic optic neuropathy显示文摘 | Leonard A Levin Roy W Beck Michael P Joseph Stuart Seiff Raymond Kraker | 1999 | Ophthalmology1999，，7： | 2 |
| 3 | Gamma irradiation of HIV-1显示文摘 | Richard A Smith Jesse Ingels John J Lochemes Joseph P Dutkowsky Linda L Pifer | 2001 | Journal of Orthopaedic Research2001，，5： | 2 |
| 4 | Age at diagnosis of type 2 diabetes and cardiovascular risk factor profile:A pooled analysis显示文摘BACKGROUND The diagnosis of type 2 diabetes(T2D)in younger adults,an increasingly common public health issue,is associated with a higher risk of cardiovascular complications and mortality,which may be due to a more adverse cardiovascular risk profile in individuals diagnosed at a younger age.AIM To investigate the association between age at diagnosis and the cardiovascular risk profile in adults with T2D.METHODS A pooled dataset was used,comprised of data from five previous studies of adults with T2D,including 1409 participants of whom 196 were diagnosed with T2D under the age of 40 years.Anthropometric and blood biomarker measurements included body weight,body mass index(BMI),waist circumference,body fat percentage,glycaemic control(HbA1c),lipid profile and blood pressure.Univariable and multivariable linear regression models,adjusted for diabetes duration,sex,ethnicity and smoking status,were used to investigate the association between age at diagnosis and each cardiovascular risk factor.RESULTS A higher proportion of participants diagnosed with T2D under the age of 40 were female,current smokers and treated with glucose-lowering medications,compared to participants diagnosed later in life.Participants diagnosed with T2D under the age of 40 also had higher body weight,BMI,waist circumference and body fat percentage,in addition to a more adverse lipid profile,compared to participants diagnosed at an older age.Modelling results showed that each one year reduction in age at diagnosis was significantly associated with 0.67 kg higher body weight[95%confidence interval(CI):0.52-0.82 kg],0.18 kg/m^(2) higher BMI(95%CI:0.10-0.25)and 0.32 cm higher waist circumference(95%CI:0.14-0.49),after adjustment for duration of diabetes and other confounders.Younger age at diagnosis was also significantly associated with higher HbA1c,total cholesterol,low-density lipoprotein cholesterol and triglycerides.CONCLUSION The diagnosis of T2D earlier in life is associated with a worse cardiovascular risk factor profile,compared to those diagnosed later in life. | Mary M Barker Francesco Zaccardi Emer M Brady Gaurav S Gulsin Andrew P Hall Joseph Henson Zin ZinHtike Kamlesh Khunti Gerald P McCann Emma L Redman David R Webb Emma G Wilmot Tom Yates Jian Yeo Melanie J Davies Jack A Sargeant | 2022 | World Journal of Diabetes2022，13，3： | 2 |
| 5 | Mode of action of the COR15a gene on the freezing tolerance of Arabidopsis thaliana 显示文摘 | STEPONKUS P L UEMURA M JOSEPH R A | 1998 | Proc Nail Acad Sci USA1998，95，14： | 1 |
| 6 | Classification of remote sensing Images having high spectral resolution显示文摘 | P H Joseph A L David | 1996 | Remote Sensing Environment1996，57，3： | 1 |
| 7 | Cold Acclimation of Arabidopsis Thalian 显示文摘 | M Uemura R A Joseph and P L Steponkus | 1995 | Plant Physiol1995，，109： | 1 |
| 8 | Information-theoretic analysis of information hiding显示文摘 | Moulin P Joseph A O | 2003 | IEEE Transactions on Information Theory2003，49，3： | 1 |
| 9 | Dynamic Mechani-cal Properties of Oil Palm Microfibril-reinforced Natural Rub-ber Composites显示文摘 | Joseph S Sreekumar P A Jose M K | 2010 | Journal of Applied Polymer Science2010，117，3： | 1 |
| 10 | 循证医学 误用漏斗图的案例分析显示文摘本文要点应该使用严格的标准对循证医学中使用的方法进行评价用于检验发表偏倚的漏斗图在系统性文献综述中应用广泛漏斗图的不对称性,无论是直观上看到的或统计学检验发现的。 | Joseph Lau John P A Ioannidis Norma Terrin Christopher H Schmid Ingram Olkin 谢朝晖 | 2007 | 英国医学杂志中文版2007，10，3： | 1 |
| 11 | Wavelet entropy for subband segmentation of EEG during in- jury and recover显示文摘 | Hasan A A Joseph S P Wendy C Z | 2003 | Annals of Biomedical Engineer- ing2003，31，6： | 1 |
| 12 | The social endocrinology of dominance: Basal testosterone predicts cortisol changes and behavior following victory and defeat显示文摘 | MEHTA P H JONES A C JOSEPHS R A | 2008 | Journal of Personality & Social Psychology2008，，94： | 1 |
| 13 | Pituitary adenoma:correlation of half-dose gadolinium-enhanced MR imaging with surgical findings in 26 patients显示文摘 | Davis P C Gokhale K A Joseph G J | 1991 | Radiology1991，180，3： | 1 |
| 14 | Pituitary adenoma:correlation of half-dose gadolinium-enhanced MR imaging with surgical findings in 26 patients显示文摘 | Davis P C Gokhale K A Joseph G J | 1991 | Radiology1991，180，3： | 1 |
| 15 | Occurence of nitrification in ehloraminated distribution systems显示文摘 | WlLCZAK A JOSEPH G JACANGELO J P | 1996 | Ammeriean Water Works Association Journal1996，88，7： | 1 |
| 16 | Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding显示文摘 | Joseph L Kim Kurt A Morgenstern James P Griffith Maureen D Dwyer John A Thomson Mark A Murcko Chao Lin Paul R Caron | 1998 | Structure1998，，1： | 1 |
| 17 | The catalytic valorization of lignin for the production of renewable chemicals显示文摘 | JOSEPH Z BRUIJNINCX P C A JONGERIUS A L | 2010 | Chem Rev2010，110，6： | 1 |
| 18 | Recent advance in techniques for hyperspectral image processing显示文摘 | Antonio P Jon A B Joseph W B Jason B Lorenzo B Gustavo C V Jocelyn C Mathieu F Paolo G Anthony G Mattia M James C T Giovanna T | 2009 | Remote Sensing of Environment2009，113，： | 1 |
| 19 | Synthesis of functionally substituted asymmetric biaryls via a novel double metal catalyzed coupling reaction 显示文摘 | JOSEPH A M ROBERT P F | 1998 | Tetrahedron Lett1998，39，40： | 1 |
| 20 | Cold acclimation of Arabidopsis thaliana:Effect on plasma membrane composition and freezing induced lesions显示文摘 | UEMURA M JOSEPH R A STEPONDUS P L | 1995 | Plant Physiol1995，109，： | 1 |
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